慢性疲労症候群患者のTSH値は対照群と同程度だったが、FT3、TT4、TT3は低値を示した。 血中T3の低下は組織レベルでのより深刻なT3不足を示唆する可能性がある。 これは、T4(チラーヂン)単独療法患者の低T3状態と類似しており、CFS病態におけるT3の重要性を示す。 https://t.co/autRvKrhpS
Higher Prevalence of "Low T3 Syndrome" in Patients With Chronic Fatigue Syndrome: A Case-Control Study.
Mentions
Extended reach
Total likes
Video views
Mentions per month
Mar 2018 – Aug 2025Where it's discussed
-
X / Twitter25 posts
-
Facebook23 posts
-
News22 articles
-
Blogs8 articles
-
Reddit6 posts
-
YouTube2 videos
AI synopsis
What people are saying
The discussions demonstrate strong support and deep interest in the research, with examples like references to thyroid dysfunction, allostasis, and metabolic implications, as well as mentions of potential treatments like T3 and niacin. The tone and wording reflect a scientific curiosity and recognition of the study's importance in shifting the perception of CFS towards a more physiological understanding.
Most discussions support the study, emphasizing its significance and aligning with the idea that hormonal and metabolic factors are important in CFS.
Participants are highly engaged, discussing specific thyroid function details, such as low T3 syndrome, and referencing related mechanisms, indicating strong interest.
Many discussions reference research methods and physiological mechanisms, showing a moderate level of deep engagement with the scientific content.
The discussions underscore that the study could influence understanding of CFS as a biological disease, with mentions of potential therapeutic approaches, indicating high perceived impact.
Abstract in brief
- The study found that patients with Chronic Fatigue Syndrome (CFS) had significantly lower levels of free T3 (FT3) and higher reverse T3 (rT3), indicating a higher prevalence of low T3 syndrome compared to healthy controls, suggesting possible thyroid function disturbances in CFS.
- The research suggests that these thyroid alterations in CFS may be linked to chronic low-grade metabolic inflammation, as evidenced by positive correlations between thyroid hormones and inflammatory markers like hsCRP, highlighting a potential role of inflammation in the disease's metabolic dysfunction.
- The findings resemble a mild form of nonthyroidal illness syndrome and low T3 syndrome seen in hypothyroid patients, pointing toward a hypometabolic state in CFS, and indicate the need for further research, potentially exploring therapies like T3 or iodide supplements.
Top posts
Most liked on X and Bluesky血中のFT3がわずかに低下している、あるいはFT3が基準範囲の下限付近にあるという所見は、標的組織における真のT3欠乏の氷山の一角を反映している可能性がある。 https://t.co/autRvKrhpS
@dr_kevinlee @KunstJonas It would fit well. Energy deficiency triggers type 1 allostatic load, leading to low T3 concentration and in severe cases a low central set point of thyroid homeostasis. Indeed, low-T3 syndrome / TACITUS was observed in ME/CFS. https://t.co/5RSEh1rw1h https://t.co/sSsywNhUij
@dr_kevinlee Higher Prevalence of “Low T3 Syndrome” in Patients With Chronic Fatigue Syndrome: A Case–Control Study https://t.co/rici9uIB7u
@dr_kevinlee The presence of a type 1 allostatic response of thyroid function suggests that ME/CFS is a real disease. https://t.co/qY9Wv7V16d
@christina4hope @MECFS_Stuttgart SPINA-GD: https://t.co/sSsywNhUij
All mentions
Understanding Low T3 Syndrome in Chronic Fatigue Patients
Patients with Chronic Fatigue Syndrome have significantly lower free T3 and higher reverse T3 levels, indicating a higher prevalence of low T3 syndrome, which may be linked to metabolic inflammation and hypometabolic…
Thyroid Dysfunction and Chronic Fatigue Syndrome Insights
A new study reveals that chronic fatigue syndrome can be linked to lower thyroid levels, specifically low T3, which may be distinct from thyroid disease. The research highlights potential metabolic and inflammatory…
慢性疲労症候群患者のTSH値は対照群と同程度だったが、FT3、TT4、TT3は低値を示した。 血中T3の低下は組織レベルでのより深刻なT3不足を示唆する可能性がある。 これは、T4(チラーヂン)単独療法患者の低T3状態と類似しており、CFS病態におけるT3の重要性を示す。 https://t.co/autRvKrhpS
血中のFT3がわずかに低下している、あるいはFT3が基準範囲の下限付近にあるという所見は、標的組織における真のT3欠乏の氷山の一角を反映している可能性がある。 https://t.co/autRvKrhpS
@IsabelRamirezRD @lowmegatron Just found this study showing thyroid dysfunction in perhaps 1/5 ‘CFS’ patients https://t.co/i6F5973XJX
@SaraGreathouse1 @EmilyCBrossard @Sabrina_Poirier 3/ https://t.co/n8gyTExy7d
Higher Prevalence of "Low T3 Syndrome" in Patients With Chronic Fatigue Syndrome: A Case-Control Study #MECFS #LowT3 https://t.co/EML8zRmZMZ
Higher Prevalence of “Low T3 Syndrome” in Patients With Chronic Fatigue Syndrome: A Case–Control Study https://t.co/JGpDbalWNq
Higher Prevalence of "Low T3 Syndrome" in Patients With Chronic Fatigue Syndrome: A Case-Control Study https://t.co/mK8TXK4jps
RT @drjwdietrich: @christina4hope @MECFS_Stuttgart SPINA-GD: https://t.co/sSsywNhUij
RT @drjwdietrich: @christina4hope @MECFS_Stuttgart SPINA-GD: https://t.co/sSsywNhUij
@christina4hope @MECFS_Stuttgart SPINA-GD: https://t.co/sSsywNhUij
@DeansKevin @angryhacademic Higher Prevalence of “Low T3 Syndrome” in Patients With Chronic Fatigue Syndrome: A Case–Control Study (2018) https://t.co/kIKTfNlFVV
https://t.co/6m6CCOESSN Schilddrüse-Endokrinologie #MECFS Höhere Prävalenz des "Low-T3-Syndroms" bei Pat. mit MECFS März 2018
@AnneSpaceCoast @quasar9uk @R_tinti @marilyngavrano1 @mecaregiver @oslersweb This was with EV encephalitis https://t.co/Kw1UwwameY
@dr_kevinlee @KunstJonas It would fit well. Energy deficiency triggers type 1 allostatic load, leading to low T3 concentration and in severe cases a low central set point of thyroid homeostasis. Indeed, low-T3 syndrome / TACITUS was observed in ME/CFS. https://t.co/5RSEh1rw1h https://t.co/sSsywNhUij
@schmirl_m @FFyviMECFS Guckt mal hier, sehr interessant, Zusammenhänge Schilddrüse/ Hypophyse/ #MECFS https://t.co/iP16KRzgFA
@iri_naa Es gibt immer mehr Studien, die zeigen, dass ME/CFS nicht eine rein psychische Erkrankung ist, sondern bedeutsame somatische Komponenten hat. Aus endokrinologischer Sicht z. B. diese: https://t.co/qY9Wv7V16d
@FionaPWME @drjwdietrich Higher Prevalence of “Low T3 Syndrome” in Patients With Chronic Fatigue Syndrome: A Case–Control Study #mecfs https://t.co/3ibwA9UW8b https://t.co/7c8CJ9L0Uo
@dr_kevinlee The presence of a type 1 allostatic response of thyroid function suggests that ME/CFS is a real disease. https://t.co/qY9Wv7V16d
RT @drjwdietrich: @dr_kevinlee Higher Prevalence of “Low T3 Syndrome” in Patients With Chronic Fatigue Syndrome: A Case–Control Study https…
RT @drjwdietrich: @dr_kevinlee Higher Prevalence of “Low T3 Syndrome” in Patients With Chronic Fatigue Syndrome: A Case–Control Study https…
@dr_kevinlee Higher Prevalence of “Low T3 Syndrome” in Patients With Chronic Fatigue Syndrome: A Case–Control Study https://t.co/rici9uIB7u
@mummyingandme @Dr_M_Guthridge Thyroid allostasis, being common in CFS, isn't covered. https://t.co/qY9Wv7V16d
Higher Prevalence of “Low T3 Syndrome” in Patients With Chronic Fatigue Syndrome: A Case–Control Study https://t.co/vTc4nefRjL #cfs #mecfs https://t.co/AmV6LcXlpR
@LillyLyle The end of the kynurenine pathway is nicotinic acid (niacin) to make NAD+. Abram Hoffer used high doses of niacin (3 to 6 grams per day) for other conditions. Some people also convert T4 to T3 less efficiently affecting the immune system. https://t.co/JGpDbaCZPq
RT @drjwdietrich: What is the chicken and what the egg? #TACITUS_Syndrome with type 1 #thyroid #allostasis in form of low #T3 syndrome in c…
G
JD
NW
SN
DH
RS
CE
C
MA
MP
ᴇE
WR
DL
M
AS