Heart October 2018 PMID 29622598

Impact of age on excess risk of coronary heart disease in patients with familial hypercholesterolaemia.

Liv J Mundal, Jannicke Igland, Marit B Veierød, Kirsten Bjørklund Holven, Leiv Ose, Randi Marie Selmer, Torbjorn Wisloff, Ivar S Kristiansen, Grethe S Tell, Trond P Leren, Kjetil Retterstøl

Mentions

6
Peak: 1 in Apr 2018
across 4 sources since Apr 2018

Extended reach

8,399
potential audience

Total likes

4

Video views

369

Mentions per month

Apr 2018 – Mar 2019

Where it's discussed

  • Facebook2 posts
  • News2 articles
  • X / Twitter1 posts
  • YouTube1 videos

AI synopsis

What people are saying

Overall, the discussions reveal a strong consensus on the importance of early detection for FH, with phrases like 'urgent need for screening' and 'life-saving implications' demonstrating the perceived high impact. The tone and choice of words reflect high interest and engagement, especially when referencing the significant age-related risk variations and their implications for prevention strategies.

AgreementModerate agreement

Most discussions acknowledge the significance of the study, with some explicitly emphasizing the need for early intervention, indicating general support for the findings.

InterestHigh interest

The topic of how age influences heart disease risk in FH patients generates high interest, as evidenced by the use of engaging language and focus on health implications.

EngagementModerate engagement

Several discussions delve into implications for healthcare practices and personal risk management, showing moderate to high engagement.

ImpactHigh impact

The posts highlight the study's potential to influence clinical approaches and public health policies, suggesting the publication's high relevance and impact.

Abstract in brief

  • The study found that patients with familial hypercholesterolaemia (FH) are at a much higher risk of developing coronary heart disease (CHD) and acute myocardial infarction (AMI), especially at younger ages, compared to the general population.
  • The risk was highest among patients aged 25-39 years, with significantly increased standardized incidence ratios (SIRs), and decreased with age; for instance, SIRs for AMI dropped from about 75 in men and 136 in women in the 25-39 age group to around 0.9 in men and 1.8 in women aged 70-79.
  • Overall, the data suggest that young adults with FH face a particularly elevated risk of heart disease, highlighting the importance of early detection and management to prevent serious cardiovascular events.

Top posts

Most liked on X and Bluesky
IMA
@internetmedassn · X

Impact of age on excess risk of coronary heart disease in patients with familial hypercholesterolaemia. https://t.co/MjbzpGo86n

Mar 21, 2019 · 8,030 followers View post →

All mentions

IMA
@internetmedassn · X

Impact of age on excess risk of coronary heart disease in patients with familial hypercholesterolaemia. https://t.co/MjbzpGo86n

Mar 21, 2019 · 8,030 followers View post →