Ann Surg January 2019 PMID 29672405

Necrotizing Soft Tissue Infection: Diagnostic Accuracy of Physical Examination, Imaging, and LRINEC Score: A Systematic Review and Meta-Analysis.

Shannon M Fernando, Alexandre Tran, Wei Cheng, Bram Rochwerg, Kwadwo Kyeremanteng, Andrew J E Seely, Kenji Inaba, Jeffrey J Perry

Mentions

15
Peak: 3 in Feb 2025
across 3 sources since Aug 2020

Extended reach

19,475
potential audience

Total likes

29

Video views

288

Mentions per month

Aug 2020 – Oct 2025

Where it's discussed

  • X / Twitter10 posts
  • Blogs3 articles
  • YouTube2 videos

AI synopsis

What people are saying

The discussions show strong interest in the diagnostic accuracy and clinical implications of the research, with many posts agreeing on the importance of early diagnosis and mentioning specific tests such as the LRINEC score and VSG. The tone is analytical and supportive, emphasizing that the review provides valuable insights for improving patient outcomes and guiding urgent surgical decisions.

AgreementModerate agreement

Most posts acknowledge the value of the systematic review and agree that early diagnosis and appropriate testing are crucial, especially with mentions of the LRINEC score's limitations and the importance of clinical judgment.

InterestHigh interest

The discussions demonstrate high interest, with mentions of specific scores, test characteristics, and clinical implications, indicating engagement with the article's findings.

EngagementModerate engagement

Posts reflect active engagement by referencing diagnostic tools like VSG and LRINEC scores, and citing specific thresholds and clinical practices, showing a thoughtful analysis of the research.

ImpactModerate impact

Participants believe that the findings can influence clinical decision-making, with some noting that the review emphasizes the need for prompt surgical intervention regardless of test results, highlighting a meaningful impact.

Abstract in brief

  • The study reviews how effective physical exams, imaging tests, and the LRINEC score are in diagnosing necrotizing soft tissue infections (NSTI) in adults, emphasizing that quick diagnosis and surgery are crucial due to the high mortality risk.
  • Key findings show that imaging with CT scans is more accurate than plain X-rays, and physical signs like fever, hemorrhagic bullae, and hypotension have variable sensitivity and specificity, meaning they are not always reliable to rule out NSTI.
  • The LRINEC score, especially with higher thresholds, has poor sensitivity and is not recommended for ruling out NSTI; instead, early surgical consultation is advised if NSTI is suspected, regardless of test results.]

Top posts

Most liked on X and Bluesky
Shaúl Navarro
@ShaulNavarro · X

El rendimiento para confirmar diagnóstico mejora con cada punto que se suma. Scores mayores a 8 tienen VPP de 93.4%. Nuestro paciente tuvo 9 puntos. En este punto, los pacientes se benefician de desbridación quirúrgica de urgencia. https://t.co/mFkXQXY173

Aug 17, 2020 · 12 likes · 2 shares · 5,320 followers View post →
@secotsecot
@secotsecot · X

✅b) VSG La fascitis necrotizante es una infección rápidamente progresiva de la piel que suele asociarse a una gran toxicidad sistémica.

Feb 3, 2025 · 11 likes · 3 shares · 6,864 followers View post →
DenverEM
@DenverEMed · X

A systematic review on test characteristics of exam, LRINEC and imaging findings for nec fasc by Fernando et al. for more info: https://t.co/LO0WDnVgla

May 12, 2021 · 2 likes · 1 share · 3,837 followers View post →
Lucas Oliveira J. e Silva (Lucas Silva)
@lucasojesilva12 · X

Really well-done DTA SR/MA Worth reading Necrotizing Soft Tissue Infection: Diagnostic Accuracy of Physical Examination, Imaging, and LRINEC Score: A System… https://t.co/avmSNOjAbR

Dec 1, 2020 · 1,086 followers View post →
Corderito⭐
@babiielamb · X

RT @ShaulNavarro: El rendimiento para confirmar diagnóstico mejora con cada punto que se suma. Scores mayores a 8 tienen VPP de 93.4%. Nues…

Aug 29, 2020 · 2 shares · 630 followers View post →
MED
@MEDTRARAQ · X

RT @secotsecot: ✅b) VSG La fascitis necrotizante es una infección rápidamente progresiva de la piel que suele asociarse a una gran toxicida…

Feb 3, 2025 · 3 shares · 548 followers View post →

All mentions

SYR(スヤァ)/形成外科
@lymphman_SYR · X

壊死性軟部組織感染症の診断に関する体系的レビュー&メタ解析

Oct 17, 2025 · 327 followers View post →
Benjamin C
@BenjaminC668105 · X

RT @secotsecot: ✅b) VSG La fascitis necrotizante es una infección rápidamente progresiva de la piel que suele asociarse a una gran toxicida…

Feb 4, 2025 · 3 shares · 1 followers View post →
MED
@MEDTRARAQ · X

RT @secotsecot: ✅b) VSG La fascitis necrotizante es una infección rápidamente progresiva de la piel que suele asociarse a una gran toxicida…

Feb 3, 2025 · 3 shares · 548 followers View post →
@secotsecot
@secotsecot · X

✅b) VSG La fascitis necrotizante es una infección rápidamente progresiva de la piel que suele asociarse a una gran toxicidad sistémica.

Feb 3, 2025 · 11 likes · 3 shares · 6,864 followers View post →
ふとねこ
@BigFatCat7 · X

メモ Necrotizing Soft Tissue Infection: Diagnostic Accuracy of Physical Examination, Imaging, and LRINEC Score: A Systematic Review and Meta-Analysis LRINECの感度はやっぱり低い https://t.co/tGw923UzGB

Jun 21, 2023 · 319 followers View post →
DenverEM
@DenverEMed · X

A systematic review on test characteristics of exam, LRINEC and imaging findings for nec fasc by Fernando et al. for more info: https://t.co/LO0WDnVgla

May 12, 2021 · 2 likes · 1 share · 3,837 followers View post →
Rohit Patnaik
@luckyrohit · X

RT @BIDMC_IDFellows: 2/ A quick review of necrotizing soft tissue infection and the LRINEC score https://t.co/G1oNRuMqu4 https://t.co/ZX9A…

Feb 17, 2021 · 2 shares · 224 followers View post →
Lucas Oliveira J. e Silva (Lucas Silva)
@lucasojesilva12 · X

Really well-done DTA SR/MA Worth reading Necrotizing Soft Tissue Infection: Diagnostic Accuracy of Physical Examination, Imaging, and LRINEC Score: A System… https://t.co/avmSNOjAbR

Dec 1, 2020 · 1,086 followers View post →
Corderito⭐
@babiielamb · X

RT @ShaulNavarro: El rendimiento para confirmar diagnóstico mejora con cada punto que se suma. Scores mayores a 8 tienen VPP de 93.4%. Nues…

Aug 29, 2020 · 2 shares · 630 followers View post →
Shaúl Navarro
@ShaulNavarro · X

El rendimiento para confirmar diagnóstico mejora con cada punto que se suma. Scores mayores a 8 tienen VPP de 93.4%. Nuestro paciente tuvo 9 puntos. En este punto, los pacientes se benefician de desbridación quirúrgica de urgencia. https://t.co/mFkXQXY173

Aug 17, 2020 · 12 likes · 2 shares · 5,320 followers View post →