April 2018 PMID 29703936

Ketogenic diet enhances neurovascular function with altered gut microbiome in young healthy mice.

David Ma, Amy C Wang, Ishita Parikh, Stefan J Green, Jared D Hoffman, George Chlipala, M Paul Murphy, Brent S Sokola, Björn Bauer, Anika M S Hartz, Ai-Ling Lin

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Mentions

44
Peak: 7 in Apr 2019
across 6 sources since Apr 2019

Extended reach

332,444
potential audience

Total likes

42

Video views

104

Mentions per month

Apr 2019 – Apr 2023

Where it's discussed

  • X / Twitter11 posts
  • Facebook11 posts
  • News11 articles
  • Blogs5 articles
  • Reddit4 posts
  • YouTube2 videos

AI synopsis

What people are saying

The overall discussions show a supportive tone with some curiosity, as seen in statements like 'Anti-aging right there' and questions about how the diet shifts gut flora, indicating a moderate level of engagement. The references to specific biological markers, such as mTOR activity and nitric oxide production, highlight that participants are engaging with the scientific details, reflecting both moderate interest and perceived impact.

AgreementModerate agreement

Most discussions seem to acknowledge and support the positive implications of the findings, with phrases like 'Anti-aging right there' indicating agreement.

InterestModerate interest

The posts express moderate curiosity, referencing specific mechanisms like gut flora changes and mTOR activity, suggesting engagement but not deep discussion.

EngagementModerate engagement

Participants refer to specific details such as blood flow, microbiome shifts, and physiological markers, showing active interest and some level of analysis.

ImpactModerate impact

The mention of anti-aging benefits and metabolic changes implies recognition of the research’s potential significance in health and aging.

Abstract in brief

  • The study found that a 16-week ketogenic diet in young healthy mice improved neurovascular functions like cerebral blood flow and blood-brain barrier transport, which are important for cognitive health and may reduce Alzheimer’s disease risk.
  • The ketogenic diet was associated with changes in the gut microbiome, increasing beneficial bacteria like Akkermansia muciniphila and Lactobacillus, while decreasing harmful, pro-inflammatory bacteria such as Desulfovibrio and Turicibacter.
  • Additionally, the diet helped reduce blood glucose and body weight, increased blood ketones, and decreased mTOR protein while boosting eNOS, all of which may contribute to better brain health and lower neurodegeneration risk.

Top posts

Most liked on X and Bluesky
P.D. Mangan Health & Freedom Maximalist
@Mangan150 · X

Ketogenic diet enhances neurovascular function with altered gut microbiome in young healthy mice *reduced mTOR activity *increased nitric oxide production *reduced blood glucose and body weight *altered gut microbiota Anti-aging right there. https://t.co/JDfCBdEfCP

Apr 6, 2019 · 28 likes · 6 shares · 294,723 followers View post →
Mike Lustgarten, PhD
@mike_lustgarten · X

Ketogenic diet enhances neurovascular function with altered gut microbiome in young healthy mice. - PubMed - NCBI https://t.co/JUxzWf9ROY

Oct 22, 2019 · 8 likes · 2 shares · 9,732 followers View post →
CureME~CFS
@Cure_ME_CFS · X

@GemzME I guess LCHF diet shifts gut flora in a way enhancing neurovascular function?? Ketogenic diet enhances neurovascular function with altered gut microbiome in young healthy mice https://t.co/rBapwRfP4c

Sep 12, 2019 · 1 like · 476 followers View post →
DiscoStew
@DiscoStew66 · X

RT @Mangan150: Ketogenic diet enhances neurovascular function with altered gut microbiome in young healthy mice *reduced mTOR activity *in…

Apr 6, 2019 · 6 shares · 10,790 followers View post →
MMA and Boxing Fight Analyst
@kostasfant · X

RT @Mangan150: Ketogenic diet enhances neurovascular function with altered gut microbiome in young healthy mice *reduced mTOR activity *in…

Apr 7, 2019 · 6 shares · 5,832 followers View post →
Larry Diamond
@natureboyrr · X

RT @Mangan150: Ketogenic diet enhances neurovascular function with altered gut microbiome in young healthy mice *reduced mTOR activity *in…

Apr 7, 2019 · 6 shares · 5,613 followers View post →

All mentions

Adi Setyawan MD
@AdiSObGyn · X

RT @mike_lustgarten: Ketogenic diet enhances neurovascular function with altered gut microbiome in young healthy mice. - PubMed - NCBI ht…

Oct 22, 2019 · 2 shares · 353 followers View post →
Mass Migration
@BChinatti · X

RT @mike_lustgarten: Ketogenic diet enhances neurovascular function with altered gut microbiome in young healthy mice. - PubMed - NCBI ht…

Oct 22, 2019 · 2 shares · 1,212 followers View post →
Mike Lustgarten, PhD
@mike_lustgarten · X

Ketogenic diet enhances neurovascular function with altered gut microbiome in young healthy mice. - PubMed - NCBI https://t.co/JUxzWf9ROY

Oct 22, 2019 · 8 likes · 2 shares · 9,732 followers View post →
CureME~CFS
@Cure_ME_CFS · X

@GemzME I guess LCHF diet shifts gut flora in a way enhancing neurovascular function?? Ketogenic diet enhances neurovascular function with altered gut microbiome in young healthy mice https://t.co/rBapwRfP4c

Sep 12, 2019 · 1 like · 476 followers View post →
Larry Diamond
@natureboyrr · X

RT @Mangan150: Ketogenic diet enhances neurovascular function with altered gut microbiome in young healthy mice *reduced mTOR activity *in…

Apr 7, 2019 · 6 shares · 5,613 followers View post →
MMA and Boxing Fight Analyst
@kostasfant · X

RT @Mangan150: Ketogenic diet enhances neurovascular function with altered gut microbiome in young healthy mice *reduced mTOR activity *in…

Apr 7, 2019 · 6 shares · 5,832 followers View post →
Keto-meatheals
@orangebobevil · X

RT @Mangan150: Ketogenic diet enhances neurovascular function with altered gut microbiome in young healthy mice *reduced mTOR activity *in…

Apr 7, 2019 · 6 shares · 1,743 followers View post →
Mass Migration
@BChinatti · X

RT @Mangan150: Ketogenic diet enhances neurovascular function with altered gut microbiome in young healthy mice *reduced mTOR activity *in…

Apr 7, 2019 · 6 shares · 1,212 followers View post →
DiscoStew
@DiscoStew66 · X

RT @Mangan150: Ketogenic diet enhances neurovascular function with altered gut microbiome in young healthy mice *reduced mTOR activity *in…

Apr 6, 2019 · 6 shares · 10,790 followers View post →
Yeow
@Yeow777 · X

RT @Mangan150: Ketogenic diet enhances neurovascular function with altered gut microbiome in young healthy mice *reduced mTOR activity *in…

Apr 6, 2019 · 6 shares · 559 followers View post →
P.D. Mangan Health & Freedom Maximalist
@Mangan150 · X

Ketogenic diet enhances neurovascular function with altered gut microbiome in young healthy mice *reduced mTOR activity *increased nitric oxide production *reduced blood glucose and body weight *altered gut microbiota Anti-aging right there. https://t.co/JDfCBdEfCP

Apr 6, 2019 · 28 likes · 6 shares · 294,723 followers View post →