Exp Gerontol July 2018 PMID 29704637

Effects of creatine supplementation on cognitive function of healthy individuals: A systematic review of randomized controlled trials.

Konstantinos I Avgerinos, Nikolaos Spyrou, Konstantinos I Bougioukas, Dimitrios Kapogiannis

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Mentions

220

Peak: 13 in Apr 2022

across 6 sources since Jan 2019

Extended reach

3,158,125

potential audience

Total likes

51,782

Video views

2,454,120

Mentions per month

Jan 2019 – Nov 2025

Where it's discussed

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YouTube17 videos
Facebook10 posts
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AI synopsis

What people are saying

The discussions reflect a generally positive outlook, emphasizing the potential cognitive benefits of creatine, especially for vegetarians or under stress, using words like 'benefits,' 'improve,' and 'potential.' Several posts reference scientific studies such as Avgerinos et al. (2018) and mention the nootropic effects, demonstrating active engagement with research, but the tone remains exploratory rather than conclusive. This mix shows a good level of curiosity and recognition of significance but stops short of strong endorsement or behavior change, correlating with the chosen scores.

AgreementModerate agreement

Most discussions acknowledge that the systematic review presents evidence supporting cognitive benefits of creatine, especially for vegetarians and in stress/diet-related contexts.

InterestHigh interest

The group shows high curiosity, with many posts referencing detailed research, potential applications, and asking questions to deepen understanding.

EngagementModerate engagement

Some posts cite specific studies and discuss biological mechanisms, indicating active participation, though most are based on references rather than in-depth independent analysis.

ImpactModerate impact

While some posts advocate for broader use and highlight the significance of findings, the overall shift in perception or widespread behavioral change remains limited, so impact is modest.

Abstract in brief

This systematic review examined whether creatine supplements can improve cognitive functions in healthy people, focusing on randomized controlled trials involving 281 individuals.
The findings suggest that creatine may help enhance short-term memory and reasoning abilities, especially in vegetarians, but its effects on other cognitive areas like long-term memory, attention, or reaction time are inconsistent.
Overall, creatine appears safe and could potentially benefit aging or stressed individuals, but more research with larger groups and tests on people with cognitive impairments, such as dementia, is needed.]

Read the full abstract

All mentions

Effects of Combining Creatine and Whey Protein on Muscle Performance

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Effects of 30 Days of Creatine Supplementation on Muscle and Brain Power

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Creatine's Impact on Lean Body Mass and Cognitive Function Analysis

Creatine supplementation generally increases lean body mass, especially with resistance training, with a notable benefit in men. It also has positive effects on brain performance, regardless of age or exercise type…

Mari Krüger · Jun 28, 2025 133,562 views

Creatine Supplementation Effects on Cognitive Performance

This video explores the effects of creatine supplementation on cognitive performance. A recent study involving 123 participants demonstrated mild benefits in cognitive tasks such as the Backward Digit Span, highlighting…

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Creatine Benefits for Memory and Cognitive Function in Healthy Adults

Exploring how creatine supplementation may improve short-term memory and reasoning, especially in vegetarians, older adults, and those experiencing stress or brain injury. More research is needed to confirm effects on…

Leonardo Alaniz · Dec 20, 2020 32,727 views

Creatine Supplementation for Cognitive Enhancement in Healthy Individuals

This video explains how creatine, an essential brain compound, supports neuronal energy supply and neuroprotection. Oral creatine may improve short-term memory, reasoning, and assist in cognitive recovery, especially in…

Dr Luciano Bruno · Mar 25, 2025 2,108 views

Impact of Creatine Levels on Women’s Health and Performance

Creatine is a vital molecule for energy production in muscles and the brain. On average, women have lower creatine levels than men, which may affect strength and cognitive functions. This video discusses the importance…

Dottor Luca · Oct 8, 2025 411 views

Is Creatine Beneficial for Brain Health and Cognitive Function

This video explores whether creatine truly enhances brain health, reviewing scientific studies. Creatine is considered one of the safest and most researched supplements.

Doc Niko Blekic · Aug 28, 2025 393 views

Creatine's Impact on Memory and Brain Function in Healthy Adults

Creatine supplementation may improve short-term memory and reasoning abilities, especially in vegetarians, and is generally safe. This review summarizes research on creatine's potential to enhance cognitive functions in…

Nutricionista Gustavo Duarte Pimentel · Jun 4, 2022 330 views

Essential Supplements for a Vegan Diet

What should you supplement if you're vegan? Vitamin B12 and protein are crucial, but important nutrients like L-Carnitine, creatine, omega-3, and nutrient greens may also be necessary. Learn how these supplements can…

Nuture · Mar 25, 2023 278 views

Creatine's Impact on Cognitive Function: Scientific Insights

This video explains the basics of creatine, its benefits for strength, muscle growth, and performance, and explores recent findings on its potential to enhance cognitive functions, especially in healthy individuals and…

The Pump Lab · May 23, 2025 273 views

Creatine and Brain Performance: Effects on Memory and Focus

Creatine isn't just for muscle gains; it can significantly boost brain performance. This video explores how creatine impacts memory, focus, and energy, highlighting its potential benefits for healthy individuals…

Dr. Bisleen Attli, ND · Feb 26, 2025 182 views

Impact of Creatine on Brain Function and Cognitive Health

This systematic review examines whether creatine supplements can improve cognitive functions in healthy individuals, focusing on randomized controlled trials involving 281 people. Creatine may enhance short-term memory…

Spinelli Psicologia · Mar 25, 2025 81 views

Creatine Supplementation and Cognitive Function: What the Research Shows

This systematic review evaluated whether creatine supplements can improve cognitive functions in healthy individuals, focusing on randomized controlled trials involving 281 people. Results suggest potential benefits for…

SoonToBeCardiologist · Sep 12, 2025 78 views

Creatine's Role in Enhancing Brain Function and Cognitive Health

This video explores the brain health benefits of creatine, including its potential to improve short-term memory and reasoning abilities, especially in vegetarians. Creatine is also discussed for its neuroprotective…

eat-healthy · Jul 25, 2023 72 views

Challenges and Benefits of Plant-Based Vegetarian Diets Explained

This video discusses the benefits and potential risks associated with vegetarian diets, including nutritional deficiencies and cognitive effects, with insights from recent research and expert analysis.

DR das Dietas · Aug 28, 2023 68 views

《吃出一點小知識》｜#1吃肌酸不只為了變壯，你的腦也在偷喝？

Open Research · Sep 16, 2025 12 views

Yo Nutricionista

@nutricionjavier · X

establecer recomendaciones definitivas. Fuentes: https://t.co/ZI5K8481GV https://t.co/mYDG43jqUE https://t.co/VHvZP2xye5 https://t.co/wPlSsMcy5T https://t.co/u23OJ2naWE https://t.co/1mB6fQ4r66

Nov 25, 2025 · 2 likes · 67,100 followers View post →

Dan Jagger

@auditorynerves.bsky.social · Bluesky

Open access systematic review: The effects of creatine supplementation on cognitive function in adults: a systematic review & meta-analysis.

Sep 21, 2025 · 5 likes View post →

DAC

@RaggedyAnn2000 · X

@AlphaWolfForce Thoughts on this. Not sure what you are looking for. Effects of creatine supplementation on cognitive function of healthy individuals: A systematic review of randomized controlled trials - PMC

Aug 26, 2025 · 1 like · 2,825 followers View post →

Coalakowski

@coalakowski · X

@emmalsalinas @zhil_arf You think this is real https://t.co/8pJZkKhRXa

Aug 22, 2025 · 384 followers View post →

Science of Fitness

@NoMoreFitLies · X

@fmfclips

Aug 6, 2025 · 1,276 followers View post →

Science of Fitness

@NoMoreFitLies · X

@NoahRyanCo

Aug 6, 2025 · 1 like · 1,276 followers View post →

Ann Currie

@Annpcurrie · X

RT @NoMoreFitLies: @foundmyfitness This study is consistent with many others that show creatine's benefits to brain health and function.…

Jul 4, 2025 · 1 share · 1,832 followers View post →

Science of Fitness

@NoMoreFitLies · X

@foundmyfitness This study is consistent with many others that show creatine's benefits to brain health and function.

Jul 4, 2025 · 2 likes · 1 share · 1,276 followers View post →

Science of Fitness

@NoMoreFitLies · X

Jul 1, 2025 · 1 like · 1,276 followers View post →

Matt Parrott

@MatthewParrott · X

@ravensherbert Creatine's promises of neurological benefits are only statistically significant when the control group are vegetarians: https://t.co/ZEa4KbsGi3

May 1, 2025 · 4,944 followers View post →

claude shannon

@catpoopburglar · X

@50percentpawg short term memory, attention, fixing sleep deprivation creatine is part of your brain's energy supply chain just like in muscles, so increasing your creatine consumption can have alot of different benefits there https://t.co/i4wRmZ8LTJ. https://t.co/2cdyVAdgPu.

Apr 29, 2025 · 2 likes · 2,466 followers View post →

Ricardo Palmerola MD

@RickyPal85 · X

Creatine showed small but significant cognitive improvements, especially in tasks involving short-term memory and intelligence: Avgerinos, K. I., et al (2018). Effects of creatine supplementation on cognitive function of healthy individuals: A systematic review of RCTs

Apr 12, 2025 · 2 likes · 59 followers View post →

Brian Decker, LMHC-D

@MendfulBrian · X

Mar 21, 2025 · 14 followers View post →

tokatti

@tokatti_ · X

では効果が見られなかったクレアチンの効果にはかなりの個人差が出た効果が出なかったデータは若者がメインのケースが多い逆に効果が出たデータはベジタリアンがメインのケースが多い https://t.co/RiPz2NMygp #自分用メモ

Mar 15, 2025 · 178 followers View post →

David

@primarycarepac.bsky.social · Bluesky

Xu C, Bi S, Zhang W, Luo L. The effects of creatine supplementation on cognitive function in adults: A systematic review and meta-analysis. Front Nutr. 2024;11:1424972. doi:10.3389/fnut.2024.1424972.

Mar 13, 2025 · 1 share View post →

sкνnxy

@skvnxy · X

@luisjgomez The neurological benefits of low-dose creatine are by-far it's greatest benefit. -- "[S]hort term memory and intelligence/reasoning may be improved by creatine" https://t.co/2SCYiazdCR

Dec 17, 2024 · 435 followers View post →

Andrew Kolasko

@AndrewKolasko · X

RT @AndrewKolasko: @PenelopeFigtree @mackinprof You are correct. A research study published in Experimental Gerontology April 25, 2018 on…

Nov 3, 2024 · 1 share · 43 followers View post →

Andrew Kolasko

@AndrewKolasko · X

@PenelopeFigtree @mackinprof You are correct. A research study published in Experimental Gerontology April 25, 2018 on the "Effects of creatine supplementation on cognitive function of healthy individuals: A systematic review of randomized controlled trials" concluded that "Oral creatine administration

Nov 2, 2024 · 1 share · 43 followers View post →

Emmanuel Sibanda

@Emmoemm · X

People forget that creatine is also a nootropic. https://t.co/bjn3xRribP My ideal supplement stack is; creatine, magnesium, tongkat ali, NAD, NAC, vitamin D, resveratrol, collagen, ginkgo biloba & zinc. It would probably be wise to couple this with blood work to monitor https://t.co/wlWy9inTI2

Sep 28, 2024 · 1 like · 2,206 followers View post →

καλές αποκριές

@mouNikolas · X

@lolalo24 @dstefanos https://t.co/2HkjGRpLAv

Aug 12, 2024 · 153 followers View post →

BowTiedPhys

@BowTiedPhys · X

[1] https://t.co/dCYylHHfoB [2] https://t.co/2WjTCRLb8P [3] https://t.co/BzxVK3V0oB [4] https://t.co/IaHT8LUaIS [5] https://t.co/H0xeGnq4oH [6] https://t.co/P8UNwzmXHT [7] https://t.co/hRWRuKTTIy [8] https://t.co/IVehmOJyxH [9] https://t.co/tFvbhHn5RJ [10] https://t.co/CrUng61kEw

Apr 4, 2024 · 2 likes · 25,415 followers View post →

Joe Ward

@BoxCarLabs · X

Multiple studies suggest creatine could help with memory, focus, and more. Check out this review for a deeper dive into the research. #creatine #brainpower #nootropics https://t.co/qrTEMi8TOw

Mar 27, 2024 · 629 followers View post →

psiphi

@psiphi_gavagai · X

@AngelicaOung Look into nootropic doses of creatine monohydrate (about 10mg/ day). It’s not a stimulate but enhances ATP in cells that give more basic metabolic energy. It enhances performance particular when stressed or sleep deprived. https://t.co/MtmTeNdRCf https://t.co/0Y2aaby9la

Mar 17, 2024 · 2 likes · 1,287 followers View post →

CaDe

@CarDen1974 · X

@ThsvndrMr @HZwartemeer Inderdaad bovendien is van creatine, wat van nature in vlees voorkomt maar niet in plantaardig voedsel, goed aangetoond dat het de intelligentie vergroot https://t.co/UbypeB0Qy4.

Mar 15, 2024 · 1 like · 222 followers View post →

Danny

@gainoholic · X

@BasedBeffJezos https://t.co/ksHqGlKysk

Feb 18, 2024 · 18 followers View post →

Dr.MarceloCavalcanti

@mhrc_psiquiatra · X

@FelipeGains https://t.co/5911Kg1dnG

Dec 16, 2023 · 10 followers View post →

Gabe King, CSNC

@gabebikes · X

@Manderville_RD It has some + research re: nootropic effects. https://t.co/Ad4pNEFZ7V

Nov 19, 2023 · 1 like · 125 followers View post →

Hubert Deep Work

@Hub_Deep_Work · X

@arthurdebons Avgerinos, Konstantinos I., Spyridon E. Spyrou, and Christos N. Bougioukas. "Effects of creatine supplementation on cognitive function of healthy individuals: A systematic review of randomized controlled trials." Experimental Gerontology 108 (2018): 166-173.

Oct 8, 2023 · 1 like · 849 followers View post →

doutora Severo

@julianassevero · X

Creatina: parece ter efeito na memória de curto prazo e no raciocínio, mas os estudos na área são poucos. Essa revisão sistemática incluiu apenas 6. Os benefícios parecem ser maiores no envelhecimento e pessoas estressadas. Avgerinos et al. (2018) doi 10.1016/j.exger.2018.04.013

Sep 15, 2023 · 2 likes · 1,786 followers View post →

Supreeth M.S.

@supreethms · X

@theliverdr https://t.co/avqB0Yp9uJ How about this?

Jun 6, 2023 · 223 followers View post →

Marcos

@marcrq11 · X

La cantidad de gente que piensa que la creatina solo se utiliza para rendimiento deportivo es pasmosa. https://t.co/ICV1ySMn9o https://t.co/R4le2AE6os

May 25, 2023 · 444 followers View post →

DrRPalmquist

@DrPalmquist · X

Effects of creatine supplementation on cognitive function of healthy individuals: A systematic review of randomized controlled trials - PubMed https://t.co/AI33moeYc3

Apr 22, 2023 · 1 like · 3,160 followers View post →

Jeremy Stamper

@jeremymstamper · X

Creatine makes you more intelligent. So why isn’t everyone taking it? https://t.co/atCNI4aiIW

Apr 3, 2023 · 32 likes · 17,615 followers View post →

Carlos Ramirez

@Getsbetterlater · X

@WiFiMoneyGuy https://t.co/XGFDMhaj4a

Nov 10, 2022 · 1 like · 490 followers View post →

brennan

@letkma · X

@seconds_0 it's also a mild nootropic if you want slightly better memory and reasoning skills (and weirder dreams) https://t.co/le4p9B7mM9

Aug 31, 2022 · 6 likes · 3,955 followers View post →

Mike Matthews

@muscleforlife · X

@JhonedDuran Gah, meant to link in first tweet. https://t.co/ydBlHI9AIs

Aug 18, 2022 · 104,694 followers View post →

Claus Carlsen

@ClausCarlsen1 · X

@ResearchGuy_org @ScepticalDoctor @BioLayne https://t.co/oLX0bBIv9H

Aug 11, 2022 · 15,688 followers View post →

Andrea de Tu Sano Equilibrio ❊

@TuSanoEquilibri · X

Effects of creatine supplementation on cognitive function of healthy individuals: A systematic review of rct. July 15th 2018. PMID: 29704637

Jun 27, 2022 · 15 likes · 6,004 followers View post →

NEETBurger.fuel

@NEETBurger · X