GFP系ホモログで、蛍光発さないカラバリがあり、一つの分子を土台に二箇所のアミノ酸のランダム飽和変異でカラバリ創出できてるのめっちゃ面白い Engineering a palette of eukaryotic chromoproteins for bacterial synthetic biology | Journal of Biological Engineering https://t.co/mNqCr41byC
Engineering a palette of eukaryotic chromoproteins for bacterial synthetic biology.
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May 2018 – Oct 2025Where it's discussed
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X / Twitter19 posts
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YouTube2 videos
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Blogs2 articles
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Bluesky1 posts
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What people are saying
Discussions highlight the significance of the chromoprotein palette for bacterial synthetic biology, with examples like individuals purchasing and testing specific proteins (e.g., eforred, purple, blue) and referencing the original article. The tone is enthusiastic and technical, emphasizing utility, stability, and potential applications, which demonstrates active engagement and recognition of the research's importance.
Most discussions acknowledge the study's contribution, with some noting the usefulness of newly tested chromoproteins.
Participants show high interest, sharing their personal purchases, using the chromoproteins, and referencing the research extensively.
Posts involve detailed mentions of practical applications, such as fitness effects and codon optimization, indicating active engagement.
While some posts indicate potential for practical use, most focus on individual experiences or appreciation rather than broad societal impact.
Abstract in brief
- The study focuses on engineering a variety of eukaryotic chromoproteins (CPs) for use in bacterial synthetic biology, highlighting their advantages over fluorescent proteins (FPs) such as ambient visibility and reduced photodamage.
- Researchers optimized and incorporated 14 different CP genes into BioBrick plasmids, examining their expression, color intensity, maturation times, and cellular fitness costs, which varied significantly among the proteins.
- To address fitness and stability issues, the team integrated the CP genes into the bacterial chromosome and engineered versions with distinct colors, providing valuable tools for research and potential field applications in biosensing and genetic marking.
Top posts
Most liked on X and BlueskyNice: a palette of eukaryotic chromoproteins for bacterial synthetic biology (HT @addgene) https://t.co/N4AM47R1Ik https://t.co/k05WBFJCN0 https://t.co/125CKYSOWL
Tested eforred, one of the chromoproteins described here https://t.co/UP3JDKxaAk as a marker. Really cute! Fitness burden, this is 48h, but stable so far. https://t.co/KGP8Ms28PB
@rt022845 Some from here. https://t.co/bsA7SkadWD
@conchoecia @GermJuggler @LABrechaun @NathanShaner Perhaps one from this paper? https://t.co/beZm6caQTx These are codon optimized for E. coli and there's 14 different options. https://t.co/RZbaHOP79K
@yo_se_o_ @shinonome_xx_ 続き)また、GFP系分子の中でも、蛍光をほとんど放出せず、光吸収のみを示す呈色タンパク質も報告されており、これらにおいても、非常にカラフルな分子群が発見・開発されています。リンクの論文なんかは非常に面白い分子改変論文になります(続く https://t.co/mNqCr4jkMK
All mentions
Exploring Colored Proteins in Synthetic Biology
Presenter Ice Cholpisit Kiattiswee from MIT discusses advancements in colored proteins during this SynBioChem mini-lecture. Discover how these proteins can enhance synthetic biology applications and their role as…
Engineering Colored Proteins for Synthetic Biology Applications
In this mini-lecture, presenter Ice Cholpisit Kiattiswee from MIT discusses engineering colored proteins for synthetic biology. The lecture is part of the SynBioChem series and highlights techniques and references…
@yo_se_o_ @shinonome_xx_ 続き)また、GFP系分子の中でも、蛍光をほとんど放出せず、光吸収のみを示す呈色タンパク質も報告されており、これらにおいても、非常にカラフルな分子群が発見・開発されています。リンクの論文なんかは非常に面白い分子改変論文になります(続く https://t.co/mNqCr4jkMK
@rt022845 Some from here. https://t.co/bsA7SkadWD
@idogenomics @markowenmartin @profvrr These are not enzymes, they are chromoproteins, a sub-set of fluorescent proteins (some do indeed fluoresce; blue one is a far-red fluorophore). Some of the references here: https://t.co/bsA7SkadWD
Links to the the Addgene page and publication from which these came... https://t.co/vV3yz4ISf5 https://t.co/1j83QjJpJk
RT @rei_nari: GFP系ホモログで、蛍光発さないカラバリがあり、一つの分子を土台に二箇所のアミノ酸のランダム飽和変異でカラバリ創出できてるのめっちゃ面白い Engineering a palette of eukaryotic chromoproteins for…
RT @rei_nari: GFP系ホモログで、蛍光発さないカラバリがあり、一つの分子を土台に二箇所のアミノ酸のランダム飽和変異でカラバリ創出できてるのめっちゃ面白い Engineering a palette of eukaryotic chromoproteins for…
RT @rei_nari: GFP系ホモログで、蛍光発さないカラバリがあり、一つの分子を土台に二箇所のアミノ酸のランダム飽和変異でカラバリ創出できてるのめっちゃ面白い Engineering a palette of eukaryotic chromoproteins for…
RT @rei_nari: GFP系ホモログで、蛍光発さないカラバリがあり、一つの分子を土台に二箇所のアミノ酸のランダム飽和変異でカラバリ創出できてるのめっちゃ面白い Engineering a palette of eukaryotic chromoproteins for…
RT @rei_nari: GFP系ホモログで、蛍光発さないカラバリがあり、一つの分子を土台に二箇所のアミノ酸のランダム飽和変異でカラバリ創出できてるのめっちゃ面白い Engineering a palette of eukaryotic chromoproteins for…
GFP系ホモログで、蛍光発さないカラバリがあり、一つの分子を土台に二箇所のアミノ酸のランダム飽和変異でカラバリ創出できてるのめっちゃ面白い Engineering a palette of eukaryotic chromoproteins for bacterial synthetic biology | Journal of Biological Engineering https://t.co/mNqCr41byC
@PatrickHorve Here are the ones I purchased: gfasPurple aeBlue meffBlue cjBlue amajLime fwYellow scOrange spisPink asPink eforRed meffRed Here is the original article where I learned these were available: https://jbioleng.biome https://t.co/Obid5lRXr8
RT @JStuttmann: Tested eforred, one of the chromoproteins described here https://t.co/UP3JDKxaAk as a marker. Really cute! Fitness burden,…
RT @JStuttmann: Tested eforred, one of the chromoproteins described here https://t.co/UP3JDKxaAk as a marker. Really cute! Fitness burden,…
Tested eforred, one of the chromoproteins described here https://t.co/UP3JDKxaAk as a marker. Really cute! Fitness burden, this is 48h, but stable so far. https://t.co/KGP8Ms28PB
@conchoecia @GermJuggler @LABrechaun @NathanShaner Perhaps one from this paper? https://t.co/beZm6caQTx These are codon optimized for E. coli and there's 14 different options. https://t.co/RZbaHOP79K
RT @joachimgoedhart: Nice: a palette of eukaryotic chromoproteins for bacterial synthetic biology (HT @addgene) https://t.co/N4AM47R1Ik htt…
RT @joachimgoedhart: Nice: a palette of eukaryotic chromoproteins for bacterial synthetic biology (HT @addgene) https://t.co/N4AM47R1Ik htt…
RT @joachimgoedhart: Nice: a palette of eukaryotic chromoproteins for bacterial synthetic biology (HT @addgene) https://t.co/N4AM47R1Ik htt…
Nice: a palette of eukaryotic chromoproteins for bacterial synthetic biology (HT @addgene) https://t.co/N4AM47R1Ik https://t.co/k05WBFJCN0 https://t.co/125CKYSOWL
Engineering a palette of eukaryotic chromoproteins for bacterial synthetic biology. - PubMed - NCBI #SynBio
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