Acad Emerg Med January 2019 PMID 29869364

Predictors of Oral Antibiotic Treatment Failure for Nonpurulent Skin and Soft Tissue Infections in the Emergency Department.

Krishan Yadav, Kathryn N Suh, Debra Eagles, John MacIsaac, Darmyn Ritchie, Jordan Bernick, Venkatesh Thiruganasambandamoorthy, George Wells, Ian G Stiell

Mentions

57
Peak: 38 in Feb 2019
across 4 sources since Oct 2018

Extended reach

877,921
potential audience

Total likes

84

Video views

186

Mentions per month

Oct 2018 – Jul 2025

Where it's discussed

  • X / Twitter52 posts
  • YouTube2 videos
  • News2 articles
  • Blogs1 articles

AI synopsis

What people are saying

Most comments express agreement with the study's importance, such as calling it a 'great paper' and referencing significant predictors like tachypnea and MRSA history, which shows shared interest and appreciation for the research. The tone varies from neutral acknowledgment to curiosity about applying findings, reflecting moderate engagement and perceived impact on practice and future research.

AgreementModerate agreement

Most discussions acknowledge the significance of the study and agree with its findings, highlighting predictors like tachypnea, ulcers, and MRSA history.

InterestModerate interest

Participants show moderate interest, frequently referencing the study's novel contributions and implications for practice.

EngagementModerate engagement

Discussions involve asking about next steps, practical applications, and details, indicating a moderate level of deep engagement.

ImpactModerate impact

The conversations suggest that the study has some influence on clinical considerations and future research directions in emergency medicine.

Abstract in brief

  • The study examined adults with nonpurulent skin infections treated in emergency departments to identify factors that predict failure of oral antibiotic treatment, which was defined by the need for hospitalization, switching antibiotics, or moving to intravenous therapy after at least 48 hours of oral treatment.
  • Key predictors of treatment failure included tachypnea at triage, chronic ulcers, a history of MRSA colonization or infection, and cellulitis within the past 12 months, with significant odds ratios indicating their strong association.
  • This research is notable as it is the first to specifically identify these predictors for oral antibiotic failure in nonpurulent skin infections in emergency settings, helping guide more effective treatment decisions.]

Top posts

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AEM Journal
@AcademicEmerMed · X

What are predictors for oral antibiotic treatment failure for cellulitis infections in the ED? Find out in @AcademicEmerMed: https://t.co/25Kw7g2L0v FREE ACCESS / #FOAMed Learn more about skin and soft tissue infections from @EMCases - https://t.co/SiXBw3A1Vt https://t.co/g0i0cv63Cf

Feb 4, 2019 · 29 likes · 25 shares · 7,366 followers View post →
AEM Journal
@AcademicEmerMed · X

#AEMJC question for author @GameYadav (and you!): How can EM providers use the risk factors you mentioned in determine disposition? Read more in @AcademicEmerMed: https://t.co/MJJIsjO2Oa FREE ACCESS / #FOAMed https://t.co/ERsNa6HtAA

Feb 5, 2019 · 17 likes · 11 shares · 7,366 followers View post →
Tamara McColl
@TamaraMcColl · X

Which pts more likely to fail PO antibiotics in cellulitis Tx? @GameYadav and colleagues @emergmedottawa provide new evidence that tachypnea at triage, chronic ulcers, MRSA hx & cellulitis in past year are assoc w tx failure. Great paper! @AcademicEmerMed https://t.co/8qpdhop7yH https://t.co/0V6rUTBPxt

Jan 29, 2019 · 11 likes · 8 shares · 1,348 followers View post →
AEM Journal
@AcademicEmerMed · X

Our final #AEMJC question for author @GameYadav: This was the first study of its kind - what are the next steps for your research in this area? Read more in @AcademicEmerMed: https://t.co/MJJIsjO2Oa FREE ACCESS / #FOAMed https://t.co/g7PIUvAOHr

Feb 8, 2019 · 10 likes · 7 shares · 7,366 followers View post →
SAEM
@SAEMonline · X

Read it online: https://t.co/GnhrW2koz3 First author: Krishan Yadav MD, MSc @AcademicEmerMed - January 2019 issue Please note: you must be an SAEM member and signed in to https://t.co/8B4FRq7Teh in order to view this article. https://t.co/QouMUS8Hp0

Jan 31, 2019 · 6 likes · 3 shares · 15,826 followers View post →
AEM Journal
@AcademicEmerMed · X

#AEMJC question for author @GameYadav (and you!): Besides the risk factors that were significant in your study, are there other factors that you suspect predict failure of outpatient abx? Learn more in @AcademicEmerMed: https://t.co/MJJIsjO2Oa FREE ACCESS / #FOAMed https://t.co/ckuJAjvKfS

Feb 7, 2019 · 5 likes · 6 shares · 7,366 followers View post →

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RT @AcademicEmerMed: Our final #AEMJC question for author @GameYadav: This was the first study of its kind - what are the next steps for y…

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RT @AcademicEmerMed: Our final #AEMJC question for author @GameYadav: This was the first study of its kind - what are the next steps for y…

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Ali S. Raja, MD
@AliRaja_MD · X

RT @AcademicEmerMed: Our final #AEMJC question for author @GameYadav: This was the first study of its kind - what are the next steps for y…

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AEM Journal
@AcademicEmerMed · X

Our final #AEMJC question for author @GameYadav: This was the first study of its kind - what are the next steps for your research in this area? Read more in @AcademicEmerMed: https://t.co/MJJIsjO2Oa FREE ACCESS / #FOAMed https://t.co/g7PIUvAOHr

Feb 8, 2019 · 10 likes · 7 shares · 7,366 followers View post →
ResusMed
@ResusMed · X

RT @AcademicEmerMed: #AEMJC question for author @GameYadav (and you!): Besides the risk factors that were significant in your study, are t…

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EM Ottawa
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RT @AcademicEmerMed: #AEMJC question for author @GameYadav (and you!): Besides the risk factors that were significant in your study, are t…

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Metrek AlMetrek,MD,MPH,PMP,CSO
@MetrekAlMetrek · X

RT @AcademicEmerMed: #AEMJC question for author @GameYadav (and you!): Besides the risk factors that were significant in your study, are t…

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SAEM
@SAEMonline · X

RT @AcademicEmerMed: #AEMJC question for author @GameYadav (and you!): Besides the risk factors that were significant in your study, are t…

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Michael Gottlieb
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RT @AcademicEmerMed: #AEMJC question for author @GameYadav (and you!): Besides the risk factors that were significant in your study, are t…

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James C. Fletcher, MD
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RT @AcademicEmerMed: #AEMJC question for author @GameYadav (and you!): Besides the risk factors that were significant in your study, are t…

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AEM Journal
@AcademicEmerMed · X

#AEMJC question for author @GameYadav (and you!): Besides the risk factors that were significant in your study, are there other factors that you suspect predict failure of outpatient abx? Learn more in @AcademicEmerMed: https://t.co/MJJIsjO2Oa FREE ACCESS / #FOAMed https://t.co/ckuJAjvKfS

Feb 7, 2019 · 5 likes · 6 shares · 7,366 followers View post →
EMCurrents
@emcurrents · X

RT @AcademicEmerMed: #AEMJC question for author @GameYadav (and you!): How can EM providers use the risk factors you mentioned in determin…

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@chernsiwit · X

RT @AcademicEmerMed: #AEMJC question for author @GameYadav (and you!): How can EM providers use the risk factors you mentioned in determin…

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Hans Rosenberg
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RT @AcademicEmerMed: #AEMJC question for author @GameYadav (and you!): How can EM providers use the risk factors you mentioned in determin…

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Eddy Lang
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EM Ottawa
@emergmedottawa · X

RT @AcademicEmerMed: #AEMJC question for author @GameYadav (and you!): How can EM providers use the risk factors you mentioned in determin…

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Michael Gottlieb
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RT @AcademicEmerMed: #AEMJC question for author @GameYadav (and you!): How can EM providers use the risk factors you mentioned in determin…

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RT @AcademicEmerMed: #AEMJC question for author @GameYadav (and you!): How can EM providers use the risk factors you mentioned in determin…

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Carlos del Pozo
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RT @AcademicEmerMed: #AEMJC question for author @GameYadav (and you!): How can EM providers use the risk factors you mentioned in determin…

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Ali S. Raja, MD
@AliRaja_MD · X

RT @AcademicEmerMed: #AEMJC question for author @GameYadav (and you!): How can EM providers use the risk factors you mentioned in determin…

Feb 5, 2019 · 11 shares · 142,616 followers View post →
AEM Journal
@AcademicEmerMed · X

#AEMJC question for author @GameYadav (and you!): How can EM providers use the risk factors you mentioned in determine disposition? Read more in @AcademicEmerMed: https://t.co/MJJIsjO2Oa FREE ACCESS / #FOAMed https://t.co/ERsNa6HtAA

Feb 5, 2019 · 17 likes · 11 shares · 7,366 followers View post →
Harbor-UCLA Emergency Medicine
@HarborUCLAEM · X

RT @AcademicEmerMed: What are predictors for oral antibiotic treatment failure for cellulitis infections in the ED? Find out in @AcademicE…

Feb 4, 2019 · 25 shares · 3,752 followers View post →
EMCurrents
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RT @AcademicEmerMed: What are predictors for oral antibiotic treatment failure for cellulitis infections in the ED? Find out in @AcademicE…

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Amani Azizalrahman
@who_else19 · X

RT @AcademicEmerMed: What are predictors for oral antibiotic treatment failure for cellulitis infections in the ED? Find out in @AcademicE…

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Hans Rosenberg
@hrosenberg33 · X

RT @AcademicEmerMed: What are predictors for oral antibiotic treatment failure for cellulitis infections in the ED? Find out in @AcademicE…

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Rob Ohle
@robertohle · X

RT @AcademicEmerMed: What are predictors for oral antibiotic treatment failure for cellulitis infections in the ED? Find out in @AcademicE…

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Michael Gottlieb
@MGottliebMD · X

RT @AcademicEmerMed: What are predictors for oral antibiotic treatment failure for cellulitis infections in the ED? Find out in @AcademicE…

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Ali S. Raja, MD
@AliRaja_MD · X

RT @AcademicEmerMed: What are predictors for oral antibiotic treatment failure for cellulitis infections in the ED? Find out in @AcademicE…

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SAEM
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RT @AcademicEmerMed: What are predictors for oral antibiotic treatment failure for cellulitis infections in the ED? Find out in @AcademicE…

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Matt Klein
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RT @AcademicEmerMed: What are predictors for oral antibiotic treatment failure for cellulitis infections in the ED? Find out in @AcademicE…

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AEM Journal
@AcademicEmerMed · X

What are predictors for oral antibiotic treatment failure for cellulitis infections in the ED? Find out in @AcademicEmerMed: https://t.co/25Kw7g2L0v FREE ACCESS / #FOAMed Learn more about skin and soft tissue infections from @EMCases - https://t.co/SiXBw3A1Vt https://t.co/g0i0cv63Cf

Feb 4, 2019 · 29 likes · 25 shares · 7,366 followers View post →
Rob Ohle
@robertohle · X

RT @SAEMonline: Read it online: https://t.co/GnhrW2koz3 First author: Krishan Yadav MD, MSc @AcademicEmerMed - January 2019 issue Please…

Jan 31, 2019 · 3 shares · 432 followers View post →
Ali S. Raja, MD
@AliRaja_MD · X

RT @SAEMonline: Read it online: https://t.co/GnhrW2koz3 First author: Krishan Yadav MD, MSc @AcademicEmerMed - January 2019 issue Please…

Jan 31, 2019 · 3 shares · 142,616 followers View post →
AEM Journal
@AcademicEmerMed · X

RT @SAEMonline: Read it online: https://t.co/GnhrW2koz3 First author: Krishan Yadav MD, MSc @AcademicEmerMed - January 2019 issue Please…

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SAEM
@SAEMonline · X

Read it online: https://t.co/GnhrW2koz3 First author: Krishan Yadav MD, MSc @AcademicEmerMed - January 2019 issue Please note: you must be an SAEM member and signed in to https://t.co/8B4FRq7Teh in order to view this article. https://t.co/QouMUS8Hp0

Jan 31, 2019 · 6 likes · 3 shares · 15,826 followers View post →
Peter Reardon
@ReardonPM · X

RT @TamaraMcColl: Which pts more likely to fail PO antibiotics in cellulitis Tx? @GameYadav and colleagues @emergmedottawa provide new evid…

Jan 30, 2019 · 8 shares · 533 followers View post →
theEDjgh
@cuttingEDjgh · X

RT @TamaraMcColl: Which pts more likely to fail PO antibiotics in cellulitis Tx? @GameYadav and colleagues @emergmedottawa provide new evid…

Jan 30, 2019 · 8 shares · 183 followers View post →
AEM Journal
@AcademicEmerMed · X

RT @TamaraMcColl: Which pts more likely to fail PO antibiotics in cellulitis Tx? @GameYadav and colleagues @emergmedottawa provide new evid…

Jan 30, 2019 · 8 shares · 7,366 followers View post →
Hans Rosenberg
@hrosenberg33 · X

RT @TamaraMcColl: Which pts more likely to fail PO antibiotics in cellulitis Tx? @GameYadav and colleagues @emergmedottawa provide new evid…

Jan 30, 2019 · 8 shares · 1,328 followers View post →
Team Venk
@TeamVenk · X

RT @TamaraMcColl: Which pts more likely to fail PO antibiotics in cellulitis Tx? @GameYadav and colleagues @emergmedottawa provide new evid…

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Ian Stiell
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RT @TamaraMcColl: Which pts more likely to fail PO antibiotics in cellulitis Tx? @GameYadav and colleagues @emergmedottawa provide new evid…

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EM Ottawa
@emergmedottawa · X

RT @TamaraMcColl: Which pts more likely to fail PO antibiotics in cellulitis Tx? @GameYadav and colleagues @emergmedottawa provide new evid…

Jan 29, 2019 · 8 shares · 6,595 followers View post →
Tamara McColl
@TamaraMcColl · X

Which pts more likely to fail PO antibiotics in cellulitis Tx? @GameYadav and colleagues @emergmedottawa provide new evidence that tachypnea at triage, chronic ulcers, MRSA hx & cellulitis in past year are assoc w tx failure. Great paper! @AcademicEmerMed https://t.co/8qpdhop7yH https://t.co/0V6rUTBPxt

Jan 29, 2019 · 11 likes · 8 shares · 1,348 followers View post →
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