Am J Physiol Endocrinol Metab October 2018 PMID 29870678

Metabolic flexibility to lipid availability during exercise is enhanced in individuals with high insulin sensitivity.

Rodrigo Fernández-Verdejo, Sudip Bajpeyi, Eric Ravussin, José E Galgani

Mentions

7
Peak: 1 in May 2020
across 3 sources since May 2020

Extended reach

120,289
potential audience

Total likes

2,735

Video views

92,861

Mentions per month

May 2020 – Aug 2023

Where it's discussed

  • YouTube3 videos
  • X / Twitter2 posts
  • Facebook2 posts

AI synopsis

What people are saying

Discussions reflect a moderate level of interest and engagement, with comments like 'MetFlex-lip seems altered' and references to prior studies, indicating readers are contemplating the implications of the research and its broader significance in metabolic health.

AgreementModerate agreement

Most discussions align with the article's findings, recognizing the relationship between insulin sensitivity and lipid adaptation during exercise.

InterestModerate interest

Participants show some interest, noting previous research and considering the implications for metabolic health.

EngagementModerate engagement

Comments reference specific mechanisms and past studies, indicating moderate depth of engagement.

ImpactModerate impact

The discourse suggests the findings could influence future research and understanding of metabolic processes.

Abstract in brief

  • The study investigates how well individuals with different levels of insulin sensitivity adapt their fat oxidation during exercise, revealing that those with high insulin sensitivity (HighIS) have better lipid flexibility compared to those with low insulin sensitivity (LowIS).
  • Researchers found that in HighIS individuals, the relationship between circulating nonesterified fatty acids (NEFA) and the respiratory quotient (RQ) is stronger, indicating more efficient adaptation of lipid oxidation to lipid availability during exercise.
  • The findings suggest that impaired metabolic flexibility in LowIS subjects may contribute to their insulin resistance, but further research is needed to determine if this relationship is causal.]

Top posts

Most liked on X and Bluesky
Nick Krontiris
@nick_krontiris · X

"...In agreement with this, we previously showed that, among healthy insulin-sensitive participants, those with lower insulin sensitivity had lower MetFlex during exercise ref: https://t.co/30mKPUPHS5

May 7, 2020 · 1 like · 19,394 followers View post →
Javi Ciborro
@papayaykware · X

https://t.co/kOEQ1fzkge en sujetos con High_IS la relación de oxidación lípido-carbohidrato se adapta a la mayor disponibilidad circulante de NEFA durante el ejercicio. Dicha MetFlex-lip parece alterada en sujetos con Low_IS. Queda por determinar si existe relación causa-efecto

Aug 25, 2023 · 8,036 followers View post →

All mentions

Javi Ciborro
@papayaykware · X

https://t.co/kOEQ1fzkge en sujetos con High_IS la relación de oxidación lípido-carbohidrato se adapta a la mayor disponibilidad circulante de NEFA durante el ejercicio. Dicha MetFlex-lip parece alterada en sujetos con Low_IS. Queda por determinar si existe relación causa-efecto

Aug 25, 2023 · 8,036 followers View post →
Nick Krontiris
@nick_krontiris · X

"...In agreement with this, we previously showed that, among healthy insulin-sensitive participants, those with lower insulin sensitivity had lower MetFlex during exercise ref: https://t.co/30mKPUPHS5

May 7, 2020 · 1 like · 19,394 followers View post →