November 2018 PMID 29895014

Implications of Placebo and Nocebo Effects for Clinical Practice: Expert Consensus.

Andrea W M Evers, Luana Colloca, Charlotte Blease, Marco Annoni, Lauren Y Atlas, Fabrizio Benedetti, Ulrike Bingel, Christian Büchel, Claudia Carvalho, Ben Colagiuri, Alia J Crum, Paul Enck, Jens Gaab, Andrew L Geers, Jeremy Howick

Mentions

58
Peak: 2 in Mar 2021
across 5 sources since Feb 2020

Extended reach

33,797
potential audience

Total likes

18

Video views

3

Mentions per month

Feb 2020 – Oct 2025

Where it's discussed

  • News35 articles
  • X / Twitter10 posts
  • Blogs9 articles
  • YouTube2 videos
  • Facebook2 posts

AI synopsis

What people are saying

The collective discussions highlight key themes such as the importance of managing nocebo responses and the need for evidence-based guidelines, exemplified by comments referencing supplementary literature and requesting further study. The tone varies from respectful disagreement to inquisitive curiosity, driven by references like the mention of related research and calls for evidence, indicating a thoughtful exchange about the article’s implications.

AgreementNeither agree nor disagree

The discussions show mixed opinions, with some acknowledging the importance of the consensus, while others question evidence or express dissent.

InterestModerate interest

Participants demonstrate moderate interest by referencing related literature and prompting further reading, indicating engagement with the topic.

EngagementModerate engagement

Several comments cite additional sources and ask for evidence, reflecting an active level of debate rather than superficial acknowledgment.

ImpactModerate impact

The dialogues suggest some recognition of the article's significance, particularly in clinical and research contexts, but not universal agreement or decisive shifts in opinion.

Abstract in brief

  • Placebo and nocebo effects are psychobiological responses that occur when patients experience outcomes influenced by their expectations, not just by the treatment itself, and are gaining attention for their potential to improve or worsen medical treatments.
  • Experts agree that maximizing positive placebo effects and reducing negative nocebo effects can lead to better patient outcomes with fewer side effects, emphasizing the importance of transparent communication and training healthcare providers.
  • The article aims to develop evidence-based and ethical guidelines for clinicians, highlighting the need for future research on how to effectively educate patients and train healthcare professionals to optimize these effects in practice.]

Top posts

Most liked on X and Bluesky
Arturo Goicoechea
@argoicoechea · X

Se admite el disenso Implications of Placebo and Nocebo Effects for Clinical Practice: Expert Consensus https://t.co/Ww2yZmNSF8

May 27, 2021 · 8 likes · 2 shares · 10,947 followers View post →
IntegralAnswers
@IntegralAnswers · X

11B/ https://t.co/nJZzZg5ftp Summary: A consensus statement on how clinicians should ethically and effectively manage nocebo responses.

May 27, 2025 · 3 likes · 8,479 followers View post →
IntegralAnswers
@IntegralAnswers · X

11A/ Evers, A. W., Colloca, L., Blease, C., et al. (2018). “Implications of placebo and nocebo effects for clinical practice: Expert consensus.” Psychotherapy and Psychosomatics, 87(4), 204–210.

May 27, 2025 · 3 likes · 8,479 followers View post →
Giacomo Rossettini
@GiacomoRoss86 · X

@LSaugman @JEsteves_osteo Dear. Thank you for your interest in the topic. The literature is not always uniform in its definitions and this can be confusing. I suggest you read further: - CFs: https://t.co/2olPtyGlkR - placebo effects vs response : https://t.co/hX1yyYSqvg

Aug 13, 2023 · 2 likes · 1 share · 2,881 followers View post →
Hsieh-Hsing Wu
@TaiwanOzPhysio · X

@timothywflynn Also this : https://t.co/itJGaG3wzM Implications of Placebo and Nocebo Effects for Clinical Practice: Expert Consensus

Feb 5, 2020 · 2 likes · 995 followers View post →
Apa
@AlpalBe · X

RT @argoicoechea: Se admite el disenso Implications of Placebo and Nocebo Effects for Clinical Practice: Expert Consensus https://t.co/Ww2y…

May 27, 2021 · 2 shares · 854 followers View post →

All mentions

IntegralAnswers
@IntegralAnswers · X

11B/ https://t.co/nJZzZg5ftp Summary: A consensus statement on how clinicians should ethically and effectively manage nocebo responses.

May 27, 2025 · 3 likes · 8,479 followers View post →
IntegralAnswers
@IntegralAnswers · X

11A/ Evers, A. W., Colloca, L., Blease, C., et al. (2018). “Implications of placebo and nocebo effects for clinical practice: Expert consensus.” Psychotherapy and Psychosomatics, 87(4), 204–210.

May 27, 2025 · 3 likes · 8,479 followers View post →
Kineblasto
@Kineblasto · X

RT @GiacomoRoss86: @LSaugman @JEsteves_osteo Dear. Thank you for your interest in the topic. The literature is not always uniform in its de…

Aug 13, 2023 · 1 share · 111 followers View post →
Giacomo Rossettini
@GiacomoRoss86 · X

@LSaugman @JEsteves_osteo Dear. Thank you for your interest in the topic. The literature is not always uniform in its definitions and this can be confusing. I suggest you read further: - CFs: https://t.co/2olPtyGlkR - placebo effects vs response : https://t.co/hX1yyYSqvg

Aug 13, 2023 · 2 likes · 1 share · 2,881 followers View post →
Apa
@AlpalBe · X

RT @argoicoechea: Se admite el disenso Implications of Placebo and Nocebo Effects for Clinical Practice: Expert Consensus https://t.co/Ww2y…

May 27, 2021 · 2 shares · 854 followers View post →
Arturo Goicoechea
@argoicoechea · X

Se admite el disenso Implications of Placebo and Nocebo Effects for Clinical Practice: Expert Consensus https://t.co/Ww2yZmNSF8

May 27, 2021 · 8 likes · 2 shares · 10,947 followers View post →
~Leaves~
@Through_Leaves · X

@HollingworthM @IMirifica @AnilvanderZee @awgaffney @statnews How can you say it is not a likely cause without providing evidence? I posted many references. Below is another article related to nocebo effects: https://t.co/QB4OwmhtTb

Mar 22, 2021 · 125 followers View post →
Aaron McEneaney
@aaron_physio · X

RT @PhysioMeScience: Implications of Placebo and Nocebo Effects for Clinical Practice: Expert Consensus. https://t.co/YR2kcEHwIj https://t…

Mar 18, 2021 · 25 shares · 736 followers View post →
~Leaves~
@Through_Leaves · X

@david_colquhoun @SciencePharmer @CaulfieldTim @CamilleJivajen @jonathanstea @TrumpKennels @RyanMarino @drrobbietee @RuthAnnHarpur Placebo effects are important in clinical settings too – please see: https://t.co/QB4OwmhtTb

Sep 30, 2020 · 125 followers View post →
Hsieh-Hsing Wu
@TaiwanOzPhysio · X

@timothywflynn Also this : https://t.co/itJGaG3wzM Implications of Placebo and Nocebo Effects for Clinical Practice: Expert Consensus

Feb 5, 2020 · 2 likes · 995 followers View post →