High glycine concentration increases collagen synthesis by articular chondrocytes in vitro: acute glycine deficiency could be an important cause of osteoarthritis.
The group generally agrees that glycine plays a crucial role in collagen synthesis and osteoarthritis prevention, as seen in comments about its high collagen content and its affordability compared to other supplements. The tone varies from informational to personal, with some participants experimenting with glycine intake or questioning its sole benefits, indicating both interest and deep engagement in evaluating its potential impact.
AgreementStrong agreement
Most discussions support the idea that increasing glycine could help with cartilage health and osteoarthritis prevention, with some posters emphasizing its affordability and importance.
InterestModerate interest
Participants show a moderate level of curiosity, sharing personal experiences with supplementation and discussing potential benefits, though some comments are more observational than exploratory.
EngagementHigh engagement
Many posts reference multiple sources, share personal reactions, and ask questions about glycine's effects, indicating a deep engagement with the topic.
ImpactHigh impact
The discussions highlight the potential of glycine supplementation to influence osteoarthritis outcomes, suggesting a significant perceived impact on health strategies.
Abstract in brief
The study shows that increasing glycine, especially at higher concentrations, significantly boosts collagen production by cartilage cells, suggesting that a diet rich in glycine could help repair cartilage and prevent osteoarthritis.
While proline and lysine improve collagen synthesis at low to moderate levels within normal physiological ranges, their effects plateau at around 10 mM, unlike glycine, which continues to have a positive impact at higher concentrations.
The findings imply that a glycine deficiency might be a key factor in reduced collagen synthesis in osteoarthritis, and enhancing glycine intake could be a promising strategy for cartilage regeneration and joint health.]
Glycine deficiency could be an important cause of osteoarthritis
"increasing glycine in the diet may well be a strategy for helping cartilage regeneration... which could contribute to the treatment and prevention of osteoarthritis." https://t.co/54msZ6s8lS
Jun 24, 2023 · 48 likes · 5 shares · 308,947 followersView post →
H
HeightOptimized
@HeightOptimized · X
https://t.co/iAq6fXiTzk
Nov 11, 2025 · 23 likes · 3 shares · 20,414 followersView post →
RS
Rene Sugar
@renesugar · X
"Glycine makes up around 33% of the collagen in the human body."
High glycine concentration increases collagen synthesis by articular chondrocytes in vitro: acute glycine deficiency could be an important cause of osteoarthritis
https://t.co/p3YKieJE20
https://t.co/6uAM9rYKig
Jan 3, 2023 · 5 likes · 2 shares · 3,985 followersView post →
RS
Rene Sugar
@renesugar · X
High glycine concentration increases collagen synthesis by articular chondrocytes in vitro: acute glycine deficiency could be an important cause of osteoarthritis
https://t.co/p3YKieJE20
"Glycine makes up around 33% of the collagen in the human body."
Feb 28, 2023 · 5 likes · 2 shares · 3,985 followersView post →
KT
Kille Tölönen
@Neonomide · X
@ScepticalDoctor Would glycine alone explain some of the seen benefits? Super cheap compared to collagen formulas (at least here): https://t.co/cnPGtAWlLn
High glycine concentration increases collagen synthesis by articular chondrocytes in vitro: acute glycine deficiency could be an important cause of osteoarthritis | Amino Acids. https://t.co/nyCPpn9p2h
Nov 11, 2025 · 3 likes · 1 share · 34,609 followersView post →
Glycine, the smallest amino acid, plays a vital role in nutrition and metabolism. Increasing glycine intake significantly boosts collagen synthesis in cartilage cells, suggesting that dietary glycine may aid in…
High glycine concentration increases collagen synthesis by articular chondrocytes in vitro: acute glycine deficiency could be an important cause of osteoarthritis | Amino Acids. https://t.co/nyCPpn9p2h
Nov 11, 2025 · 3 likes · 1 share · 34,609 followersView post →
H
HeightOptimized
@HeightOptimized · X
https://t.co/iAq6fXiTzk
Nov 11, 2025 · 23 likes · 3 shares · 20,414 followersView post →
H
Hibiscus
@Hibisket007 · X
Just got some of this today and I’m trying it right now. I put a tbs in water and it doesn’t taste bad at all.
Glycine Nutrition Advice - Glycine Supplementation https://t.co/UpDi04zXeA via @YouTube
Oct 11, 2025 · 1 like · 2,919 followersView post →
中壮
中武 壮以知
@soichinakatake · X
「食事中のグリシンを増やすことは、コラーゲン合成を促進することで軟骨再生を助ける戦略である可能性」
High glycine concentration increases collagen synthesis by articular chondrocytes in vitro: acute glycine deficiency ... https://t.co/w81us94BR1
High glycine concentration increases collagen synthesis by articular chondrocytes in vitro: acute glycine deficiency could be an important cause of osteoarthritis - PMC https://t.co/BzP63V4m7S
@AlpacaAurelius the study excerpt is talking about glycine, glycine is much cheaper than collagen.
10 gm per day glycine + low dose proline & lysine
https://t.co/QXG1usGso6
Nov 28, 2023 · 2 likes · 18,568 followersView post →
J
Jen
@Celestite66 · X
RT @Mangan150: Glycine deficiency could be an important cause of osteoarthritis
"increasing glycine in the diet may well be a strategy for…
Nov 28, 2023 · 5 shares · 2,414 followersView post →
K
kike
@FUENTESMANZULLI · X
RT @Mangan150: Glycine deficiency could be an important cause of osteoarthritis
"increasing glycine in the diet may well be a strategy for…
Jun 26, 2023 · 5 shares · 249 followersView post →
B
Bill
@fourthgulch · X
RT @Mangan150: Glycine deficiency could be an important cause of osteoarthritis
"increasing glycine in the diet may well be a strategy for…
Jun 24, 2023 · 5 shares · 600 followersView post →
PM
P.D. Mangan Health & Freedom Maximalist
@Mangan150 · X
Glycine deficiency could be an important cause of osteoarthritis
"increasing glycine in the diet may well be a strategy for helping cartilage regeneration... which could contribute to the treatment and prevention of osteoarthritis." https://t.co/54msZ6s8lS
Jun 24, 2023 · 48 likes · 5 shares · 308,947 followersView post →
W
Wolfey102
@Wolfey102 · X
Glycine Nutrition Advice - Glycine Supplementation https://t.co/G4e8YO5iBh via @YouTube
High glycine concentration increases collagen synthesis by articular chondrocytes in vitro: acute glycine deficiency could be an important cause of osteoarthritis - PMC https://t.co/BzP63V4m7S
@flowtiina @MaijaSol @UrsulaSchwab Äskeinen tulos oli ihmisillä, mutta myös esim koeputkessa kondrosyyteillä glysiinillä voi lisätä kollageenin tuotantoa: https://t.co/H8vILVgHGW
@ScepticalDoctor Would glycine alone explain some of the seen benefits? Super cheap compared to collagen formulas (at least here): https://t.co/cnPGtAWlLn
High glycine concentration increases collagen synthesis by articular chondrocytes in vitro: acute glycine deficiency could be an important cause of osteoarthritis - PMC https://t.co/BzP63V4m7S
RT @renesugar: High glycine concentration increases collagen synthesis by articular chondrocytes in vitro: acute glycine deficiency could b…
Mar 1, 2023 · 2 shares · 1,171 followersView post →
RS
Rene Sugar
@renesugar · X
High glycine concentration increases collagen synthesis by articular chondrocytes in vitro: acute glycine deficiency could be an important cause of osteoarthritis
https://t.co/p3YKieJE20
"Glycine makes up around 33% of the collagen in the human body."
Feb 28, 2023 · 5 likes · 2 shares · 3,985 followersView post →
MR
Marlene Robin
@TheVitalClub · X
RT @renesugar: "Glycine makes up around 33% of the collagen in the human body."
High glycine concentration increases collagen synthesis by…
RT @renesugar: "Glycine makes up around 33% of the collagen in the human body."
High glycine concentration increases collagen synthesis by…
Jan 3, 2023 · 2 shares · 16,733 followersView post →
RS
Rene Sugar
@renesugar · X
"Glycine makes up around 33% of the collagen in the human body."
High glycine concentration increases collagen synthesis by articular chondrocytes in vitro: acute glycine deficiency could be an important cause of osteoarthritis
https://t.co/p3YKieJE20
https://t.co/6uAM9rYKig
Jan 3, 2023 · 5 likes · 2 shares · 3,985 followersView post →
RS
Rene Sugar
@renesugar · X
"Glycine makes up around 33% of the collagen in the human body."
High glycine concentration increases collagen synthesis by articular chondrocytes in vitro: acute glycine deficiency could be an important cause of osteoarthritis
https://t.co/p3YKieJE20
https://t.co/6uAM9rYKig
RT @epigeneticcode: High glycine concentration increases #collagen synthesis by articular chondrocytes in vitro: acute glycine deficiency c…
Jan 20, 2022 · 1 share · 1,198 followersView post →
H
Healthspan
@epigeneticcode · X
High glycine concentration increases #collagen synthesis by articular chondrocytes in vitro: acute glycine deficiency could be an important cause of osteoarthritis glycine deficiency could be an important cause of #osteoarthritis
https://t.co/eWgQa2I5xR
Jan 20, 2022 · 3 likes · 1 share · 356 followersView post →
HG
Hypnosis4Gnosis
@HGnosis · X
Glycine Nutrition Advice - Glycine Supplementation https://t.co/2kOJovhGKS via @YouTube
@PlomeekSoup @The_Nutrivore Sg like these?
https://t.co/N2pCqE1A87
https://t.co/agpA35McTr
May 1, 2020 · 1 like · 25,813 followersView post →
N
Whey Protein Quality for Athletes | PDF | Proteins | Amino Acid
News
org/10.1007/s00726-018-2611-x. PMid:30006659. requirements in human nutrition: report of a joint FAO/WHO/ Pennings, B., Boirie, Y., Senden, J. M., Gijsen ...
High Glycine Concentration Increases Collagen Synthesis by ...
News
Amino Acids (2018) 50:1357–1365. https://doi.org/10.1007/s00726-018-2611-x. ORIGINAL ARTICLE. High glycine concentration increases collagen synthesis by ...