Discussions emphasize the study's demonstration of long-term exercise effects on muscle and cardiovascular health, with participants saying things like 'fiber type differences were the most unexpected' and noting the 'phenotypic plasticity' involved. The tone is curious and analytical, reflecting high engagement and recognition of the study's potential to influence understanding of muscle adaptation and health strategies.
AgreementStrong agreement
Most discussions acknowledge the study's findings, emphasizing the influence of long-term exercise on muscle and cardiovascular health in genetically identical individuals.
InterestHigh interest
The discussions show high interest, with participants highlighting specific aspects like fiber type differences and molecular markers, indicating engagement with the scientific details.
EngagementHigh engagement
Responders analyze the study's implications, sharing personal insights, asking questions, and referencing related research, demonstrating deep engagement.
ImpactHigh impact
The discussions suggest the study could significantly influence perspectives on muscle plasticity and exercise's role in health, as participants consider its broader implications.
Abstract in brief
The study compares a pair of 52-year-old monozygotic twins with 30 years of different exercise habits, finding that the twin who trained regularly has better cardiovascular health and body composition but smaller and less muscular legs.
The twin with endurance training shows higher levels of certain muscle fiber types, molecular markers related to muscle health, and greater aerobic capacity, suggesting that long-term exercise significantly influences muscle and cardiovascular systems.
The findings emphasize that both genetic factors and long-term environmental exposure (like exercise) play a crucial role in muscle health and that muscle systems may be more adaptable than previously believed, especially in genetically identical individuals.
Twin studies can be quite interesting. One twin is a sedentary truck driver, and the other is a high school coach who has done marathons and triathlons for 30 years. The fiber type differences were the most unexpected for me. https://t.co/hoUWw4XXcr
"Muscle health and performance in monozygotic twins with 30 years of discordant exercise habits"
https://t.co/u0HcMtbK5W
Dec 4, 2025 · 28 likes · 1 share · 29,396 followersView post →
JD
John Davis
@JDruns · X
When writing my critical speed article I came across this awesome study on a pair of identical twins in their 50s. One was a sedentary truck driver, the other was a 3:01 marathoner with 40,000 miles of training logged in the previous 30 years 10.1007/s00421-018-3943-7
Jan 5, 2024 · 10 likes · 1,731 followersView post →
@GaryMarcus @ylecun @rogerkmoore Thx - as a physiologist always interested in phenotypic plasticity… stuff like this is most interesting.
https://t.co/lk2lAiLnZL
Jan 5, 2023 · 2 likes · 16,710 followersView post →
O
OJSN
@iamojsn · X
(PDF) Muscle health and performance in monozygotic twins with 30 years of discordant exercise habits - https://t.co/Psyz2u6iIO
May 11, 2022 · 2 likes · 14,976 followersView post →
Training hard yet not seeing results? These invisible errors, often overlooked, may be the cause. Learn how stress, distractions, comparisons, and inaccurate measurements impact your fitness journey, supported by…
This video explains how muscles function and what happens when you exercise, highlighting the significant impact of long-term training on muscle health and cardiovascular performance, based on scientific research…
Athlete endurance training combines strength and endurance through techniques like sandbag training. This method recruits high-threshold motor units efficiently, improving both muscular strength and cardiovascular…
This video explores the effectiveness of high-intensity interval training (HIIT) compared to continuous endurance training in improving VO2max. We analyze findings from numerous controlled trials to provide insights…
RT @lefineder: "Muscle health and performance in monozygotic twins with 30 years of discordant exercise habits"
https://t.co/u0HcMtbK5W
Dec 4, 2025 · 1 share · 1,708 followersView post →
L
LiorLefineder
@lefineder · X
"Muscle health and performance in monozygotic twins with 30 years of discordant exercise habits"
https://t.co/u0HcMtbK5W
Dec 4, 2025 · 28 likes · 1 share · 29,396 followersView post →
WL
William Lagakos
@caloriesproper2 · X
European Journal of Applied Physiology https://t.co/9b10Hh0kPa https://t.co/EmQz9CgYTl
Jul 20, 2025 · 1 like · 3,245 followersView post →
JD
John Davis
@JDruns · X
When writing my critical speed article I came across this awesome study on a pair of identical twins in their 50s. One was a sedentary truck driver, the other was a 3:01 marathoner with 40,000 miles of training logged in the previous 30 years 10.1007/s00421-018-3943-7
Jan 5, 2024 · 10 likes · 1,731 followersView post →
JM
Jose Magana
@vjoe17vjoe17 · X
Muscle health and performance in monozygotic twins with 30 years of discordant exercise habits https://t.co/bc1cFoWRgf
An interesting study compares exercise histories in monozygotic twins and the long-term adaptation in muscle fibers and other parameters. https://t.co/A4VmyhhYJp
Twin studies can be quite interesting. One twin is a sedentary truck driver, and the other is a high school coach who has done marathons and triathlons for 30 years. The fiber type differences were the most unexpected for me. https://t.co/hoUWw4XXcr
@RoryPaltridge @DrAndyGalpin An interesting study on identical twins, and how fiber distribution differed, due to activity differences: https://t.co/W6RlK6odyF
@GaryMarcus @ylecun @rogerkmoore Thx - as a physiologist always interested in phenotypic plasticity… stuff like this is most interesting.
https://t.co/lk2lAiLnZL
Jan 5, 2023 · 2 likes · 16,710 followersView post →
O
OJSN
@iamojsn · X
Muscle health and performance in monozygotic twins with 30 years of discordant exercise habits - PubMed - https://t.co/eMrKGkyR6U
同じだけどこっちのがいいか
(PDF) Muscle health and performance in monozygotic twins with 30 years of discordant exercise habits - https://t.co/Psyz2u6iIO
May 11, 2022 · 2 likes · 14,976 followersView post →
M
Madhu
@madhukarbk · X
"Conclusions: Several measured differences are the largest reported between MZ twins (TT expressed 55% more MHC I fibers, 12.4 ml/kg/min greater VO2max, and 8.6% lower body fat% vs. UT)..."
(1/2) https://t.co/oXlF87lw3O
doi:10.1007/s00421- can play a role. First, it is critical to point out that the athletes 018-3943-7. involved in these performances have passed numerous ...
SS
L
JD
JP
MJ
O
JG
WL
JM
JA
C
WY
MP
A
KS
CL
JT
WB
WA
LT
RG
A
TB
AC
K
NL
TD
TK
RS
GS
GG
M
GB
DP