Neurogastroenterol Motil September 2018 PMID 30062794

Demonstration of differences in colonic volumes, transit, chyme consistency, and response to psyllium between healthy and constipated subjects using magnetic resonance imaging.

G Major, K Murray, G Singh, A Nowak, C L Hoad, L Marciani, A Silos-Santiago, C B Kurtz, J M Johnston, P Gowland, R Spiller

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Mentions

15
Peak: 2 in Jan 2022
across 4 sources since Dec 2018

Extended reach

3,809
potential audience

Total likes

71

Video views

1,628

Mentions per month

Dec 2018 – Jan 2025

Where it's discussed

  • News9 articles
  • X / Twitter2 posts
  • YouTube2 videos
  • Blogs2 articles

AI synopsis

What people are saying

The posts express caution about the quality of data and note the overlap in stool volumes between different groups, indicating a cautious and critical tone. The brief mention of experts and references reflects limited engagement and focus on skepticism rather than exploring the study's potential implications.

AgreementLow agreement

The discussion questions the strength of the conclusions, highlighting concerns about data quality and overlapping results, which shows some disagreement with the publication's significance.

InterestModerate interest

The focus is limited to skepticism about data rather than broader implications, indicating moderate interest rather than high enthusiasm.

EngagementNeutral engagement

The comments are brief and mostly transactional, reflecting some recognition but not deep discussion or detailed analysis.

ImpactLow impact

The skepticism suggests the findings may not be considered transformative or widely impactful by these commenters.

Abstract in brief

  • This study shows that magnetic resonance imaging (MRI) can effectively differentiate between healthy individuals and those with constipation by measuring colonic volume, transit time, and chyme consistency, especially after taking psyllium.
  • Psyllium increases colonic water content and volume in both groups, but the effects and transit times are different: constipation patients have slower transit and lower T1 relaxation times in the descending colon, which improve with psyllium.
  • MRI data suggests that changes in the T1 relaxation time of the descending colon correlate with stool water content and frequency, indicating MRI could be a useful objective biomarker for evaluating gut function and responses to constipation treatments.]

Top posts

Most liked on X and Bluesky
Andrew Plumb
@aaoplumb · X

@DrHenryK @UKGastroDr @AntonEmmanuel2 @Radiopaedia

Jan 16, 2022 · 1 like · 1,036 followers View post →
Andrew Plumb
@aaoplumb · X

There is no good quality data AFAIK. But what IS known is that there is significant overlap in stool volumes between controls and patients with IBS-C and FC. For example: https://t.co/ZXwwjQMfDY https://t.co/7GrnLReOxL

Jan 16, 2022 · 1,036 followers View post →

All mentions

Andrew Plumb
@aaoplumb · X

There is no good quality data AFAIK. But what IS known is that there is significant overlap in stool volumes between controls and patients with IBS-C and FC. For example: https://t.co/ZXwwjQMfDY https://t.co/7GrnLReOxL

Jan 16, 2022 · 1,036 followers View post →
Andrew Plumb
@aaoplumb · X

@DrHenryK @UKGastroDr @AntonEmmanuel2 @Radiopaedia

Jan 16, 2022 · 1 like · 1,036 followers View post →
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