The discussions highlight the promising role of SCFAs in alleviating stress-related effects, exemplified by phrases like 'wow' and questions about mechanisms. The tone reflects enthusiasm and curiosity, with posts emphasizing the potential for therapeutic development and recognizing the contributions of research teams, thus supporting moderate to high interest and agreement.
AgreementModerate agreement
Most posts acknowledge the positive findings, with some emphasizing the potential therapeutic implications of SCFAs.
InterestHigh interest
Discussions show high interest, especially with posts questioning mechanisms and therapeutic potential, reflecting curiosity and relevance.
EngagementModerate engagement
The posts include references to mechanisms, team acknowledgments, and calls to explore applications, indicating a moderate level of engagement.
ImpactModerate impact
While the discussion recognizes significance, it primarily remains within the realm of research endorsement rather than demonstrating immediate or profound societal impact.
Abstract in brief
Short-chain fatty acids (SCFAs) are microbial metabolites that can help reduce stress-induced changes in the brain-gut axis, such as behaviors associated with depression and increased intestinal permeability, though they do not affect overall body weight or the gene expression of certain SCFA receptors.
Chronic psychosocial stress alters gut microbiota and causes behavioral and physiological issues, but supplementing with SCFAs in mice can alleviate some of these stress-related effects, indicating a potential for microbiota-targeted therapies for stress-related disorders.
The study highlights the important role of microbiota-derived SCFAs in maintaining brain and gut health under stress, emphasizing their potential to modulate immune function, behavior, and metabolism through gut-brain communication pathways.]
Nov 5, 2019 · 12 likes · 1 share · 9,636 followersView post →
DJ
Dr. Sheba A-J
@ShebaAJ · X
Short chain fatty acids block selective effects of chronic psychosocial stress. wow. What is the mechanism tho? can we mine these molecules for therapy?
https://t.co/CmkfBtgW89
@jfcryan @iScience_CP
Aug 6, 2020 · 4 likes · 2 shares · 2,989 followersView post →
U
UltimApe
@ultimape · X
"Considering that these behavioural parameters are negatively affected by chronic (psychosocial) stress [...], we hypothesised that SCFA supplementation could ameliorate these psychosocial stress‐induced behavioural deficits."
https://t.co/dZHrFUILR1
Oct 20, 2020 · 1 like · 1 share · 6,767 followersView post →
JC
John F. Cryan
@jfcryan · X
RT @ShebaAJ: Short chain fatty acids block selective effects of chronic psychosocial stress. wow. What is the mechanism tho? can we mine t…
Aug 6, 2020 · 2 shares · 22,436 followersView post →
GM
Geoffroy Mallaret
@MallaretG · X
RT @ShebaAJ: Short chain fatty acids block selective effects of chronic psychosocial stress. wow. What is the mechanism tho? can we mine t…
A dive into psychobiotics research reveals how ingestion of Lactobacillus strains may influence emotional behavior. Join us as we explore fascinating studies linking gut health and mental wellness.
A healthy gut supports a balanced nervous system and vice versa. Learn how dietary fibers and enhancing microbiota-derived short-chain fatty acids can alleviate stress-related gut and brain issues, promoting overall…
"Considering that these behavioural parameters are negatively affected by chronic (psychosocial) stress [...], we hypothesised that SCFA supplementation could ameliorate these psychosocial stress‐induced behavioural deficits."
https://t.co/dZHrFUILR1
Oct 20, 2020 · 1 like · 1 share · 6,767 followersView post →
GM
Geoffroy Mallaret
@MallaretG · X
RT @ShebaAJ: Short chain fatty acids block selective effects of chronic psychosocial stress. wow. What is the mechanism tho? can we mine t…
RT @ShebaAJ: Short chain fatty acids block selective effects of chronic psychosocial stress. wow. What is the mechanism tho? can we mine t…
Aug 6, 2020 · 2 shares · 22,436 followersView post →
DJ
Dr. Sheba A-J
@ShebaAJ · X
Short chain fatty acids block selective effects of chronic psychosocial stress. wow. What is the mechanism tho? can we mine these molecules for therapy?
https://t.co/CmkfBtgW89
@jfcryan @iScience_CP
Aug 6, 2020 · 4 likes · 2 shares · 2,989 followersView post →
Nov 5, 2019 · 12 likes · 1 share · 9,636 followersView post →
MB
Marcus Böhme
@boehmemarcus.bsky.social · Bluesky
Our latest paper is out on short-chain fatty acids alleviating stress‐induced brain‐gut axis alterations. Delighted to be a part of a great team @jfcryan, @TedDinan @OrlaOS, @UCCpsychiatry, @Stancat01. Well done @marcel_wouw https://physoc.onlinelibrary.wiley.com/doi/10.1113/JP276431
jir-18-13183 | PDF | Inflammatory Bowel Disease | Gastrointestinal ...
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