JAMA Cardiol September 2018 PMID 30073316

Efficacy and Safety of Further Lowering of Low-Density Lipoprotein Cholesterol in Patients Starting With Very Low Levels: A Meta-analysis.

Marc S Sabatine, Stephen D Wiviott, KyungAh Im, Sabina A Murphy, Robert P Giugliano

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Mentions

58
Peak: 4 in Aug 2024
across 5 sources since Aug 2018

Extended reach

64,879
potential audience

Total likes

7,036

Video views

62,193

Mentions per month

Aug 2018 – Sep 2025

Where it's discussed

  • Facebook21 posts
  • News20 articles
  • X / Twitter9 posts
  • YouTube4 videos
  • Blogs4 articles

AI synopsis

What people are saying

Several discussions highlight skepticism about lowering LDL cholesterol further in individuals already at low levels, such as mentions of

AgreementNeither agree nor disagree

The discussions show mixed reactions, with some skepticism about extending LDL lowering beyond already low levels, indicating no strong consensus for or against the findings.

InterestModerate interest

The posts indicate some curiosity, especially about side effects and implications, but overall engagement with the content appears moderate.

EngagementModerate engagement

Participants reference specific concepts like side effects and subgroup responses, suggesting a moderate level of thoughtful involvement.

ImpactNeutral impact

The overall tone suggests that the publication sparks some concern and curiosity, but does not appear to be perceived as a revolutionary or highly impactful change.

Top posts

Most liked on X and Bluesky
Tom Babington
@Tom_Babington1 · X

@The_Nutrivore Also interested in her explaining the "debilitating side effects" https://t.co/DyhiJ0I5dX https://t.co/PaPTbguE9c https://t.co/JTKETcth3F

Jun 22, 2022 · 4 likes · 1,202 followers View post →
زينب الشيـخ
@zainab_559 · X

As low As possible https://t.co/YVob6tY15q

Jun 18, 2025 · 1 like · 531 followers View post →
Kevin Harris
@kevtharris · X

@anti_wokeist @samstone46 @robertlufkinmd https://t.co/xOo1l4NAL0 nor does it hold up when we take people with already low levels of LDL-c & lower it even further

Aug 10, 2022 · 540 followers View post →
anton
@TariroAnton · X

@jcjcnavarro @farmagemma https://t.co/Pel0CqLIap

May 6, 2022 · 141 followers View post →
anton
@TariroAnton · X

@fguzon https://t.co/Pel0CqLIap

May 6, 2022 · 141 followers View post →
Maximus Tiberius
@daveyx2 · X

@nicknorwitz Agree with your evidence for the subset LMHR who may have better RCT. For the rest of us.... Efficacy and Safety of Further Lowering of Low-Density Lipoprotein Cholesterol in Patients Starting With Very Low Levels: A Meta-analysis | Cardiology | JAMA Cardiology | JAMA Network

Aug 31, 2024 · 33 followers View post →

All mentions

زينب الشيـخ
@zainab_559 · X

As low As possible https://t.co/YVob6tY15q

Jun 18, 2025 · 1 like · 531 followers View post →
Maximus Tiberius
@daveyx2 · X

@nicknorwitz Agree with your evidence for the subset LMHR who may have better RCT. For the rest of us.... Efficacy and Safety of Further Lowering of Low-Density Lipoprotein Cholesterol in Patients Starting With Very Low Levels: A Meta-analysis | Cardiology | JAMA Cardiology | JAMA Network

Aug 31, 2024 · 33 followers View post →
Maximus Tiberius
@daveyx2 · X

@SvenEriksson17 @AnthunBj @brownenglisman @nicknorwitz @realDaveFeldman @khurramn1 Efficacy and Safety of Further Lowering of Low-Density Lipoprotein Cholesterol in Patients Starting With Very Low Levels: A Meta-analysis | Cardiology | JAMA Cardiology | JAMA Network

Aug 31, 2024 · 33 followers View post →
Maximus Tiberius
@daveyx2 · X

@RacecarengTom @Drlipid Efficacy and Safety of Further Lowering of Low-Density Lipoprotein Cholesterol in Patients Starting With Very Low Levels: A Meta-analysis | Cardiology | JAMA Cardiology | JAMA Network

Aug 31, 2024 · 33 followers View post →
Maximus Tiberius
@daveyx2 · X

@Drlipid Efficacy and Safety of Further Lowering of Low-Density Lipoprotein Cholesterol in Patients Starting With Very Low Levels: A Meta-analysis | Cardiology | JAMA Cardiology | JAMA Network

Aug 31, 2024 · 33 followers View post →
Kevin Harris
@kevtharris · X

@anti_wokeist @samstone46 @robertlufkinmd https://t.co/xOo1l4NAL0 nor does it hold up when we take people with already low levels of LDL-c & lower it even further

Aug 10, 2022 · 540 followers View post →
Tom Babington
@Tom_Babington1 · X

@The_Nutrivore Also interested in her explaining the "debilitating side effects" https://t.co/DyhiJ0I5dX https://t.co/PaPTbguE9c https://t.co/JTKETcth3F

Jun 22, 2022 · 4 likes · 1,202 followers View post →
anton
@TariroAnton · X

@fguzon https://t.co/Pel0CqLIap

May 6, 2022 · 141 followers View post →
anton
@TariroAnton · X

@jcjcnavarro @farmagemma https://t.co/Pel0CqLIap

May 6, 2022 · 141 followers View post →