Cell Metab October 2018 PMID 30078554

Remission of Human Type 2 Diabetes Requires Decrease in Liver and Pancreas Fat Content but Is Dependent upon Capacity for β Cell Recovery.

Roy Taylor, Ahmad Al-Mrabeh, Sviatlana Zhyzhneuskaya, Carl Peters, Alison C Barnes, Benjamin S Aribisala, Kieren G Hollingsworth, John C Mathers, Naveed Sattar, Michael E J Lean

Mentions

86
Peak: 3 in Sep 2019
across 6 sources since Jan 2019

Extended reach

327,364
potential audience

Total likes

64

Video views

305

Mentions per month

Jan 2019 – Nov 2025

Where it's discussed

  • News40 articles
  • X / Twitter23 posts
  • Facebook14 posts
  • Blogs5 articles
  • YouTube2 videos
  • Reddit2 posts

AI synopsis

What people are saying

Overall, comments demonstrate strong agreement with the findings, particularly emphasizing the role of organ fat reduction and beta cell recovery, while the tone indicates curiosity and a desire to understand the mechanisms involved. Many posts include references to trials like DiRECT and specific metrics such as liver fat content, reflecting deep engagement and perceived importance of the research in advancing diabetes treatment.

AgreementModerate agreement

Most discussions reflect support or acceptance of the study’s findings, emphasizing the connection between decreasing organ fat and diabetes remission.

InterestHigh interest

Participants show high interest, often referencing specific studies, metrics, and concepts like pancreatic beta-cell recovery.

EngagementModerate engagement

Several posts delve into detailed analysis, such as the importance of beta cell capacity and weight loss, indicating thoughtful engagement.

ImpactHigh impact

The discussions suggest this research could influence treatment approaches and public understanding of diabetes reversibility.

Top posts

Most liked on X and Bluesky
P.D. Mangan Health & Freedom Maximalist
@Mangan150 · X

Remission of Human Type 2 Diabetes Requires Decrease in Liver and Pancreas Fat Content but Is Dependent upon Capacity for beta Cell Recovery But is it really? The non-responders did not lose as much weight and remained obese. That's the big difference. https://t.co/b49Mn8Fkeh

Jan 7, 2024 · 26 likes · 1 share · 294,719 followers View post →
Alex Leaf
@AlexJLeaf · X

Importantly, a secondary analysis of the DiRECT trial found, once again, that T2DM reversal will occur in only those whose pancreas is able to resume normal functionality and insulin secretion ability. https://t.co/I4qRsZbXVF

Jan 22, 2023 · 10 likes · 4,410 followers View post →
BANT
@BANTonline · X

How did SACN ignore fatty liver in type 2 diabetes ? https://t.co/WNpxqlsl3P

Apr 14, 2020 · 8 likes · 1 share · 7,663 followers View post →
Harmless Frog
@FrogHarmless · X

@raphaels7 @tednaiman https://t.co/Rid8hynZVK https://t.co/7vbPMhyi1z

May 5, 2024 · 2 likes · 502 followers View post →
Adam Jaworski
@adam__jaworski · X

@lekarzsuwala @LeskiPiotr @MagdalenaOTR NIE. Mowa tu o 46% ludzi z grupy eksperym. po diagnozie cukrzycy T2 do 6 lat. Niewykluczone, że okres może być dłuższy w konkretnych przypadkach. Zależne od "stanu" komórek β trzustki, ale precyzyjne punkty odcięcia - wciąż niezdefiniowane... https://t.co/k1y24opoj7 https://t.co/3kQe4RjdG5

May 8, 2022 · 2 likes · 84 followers View post →
Mark Maslow
@MarkMaslow · X

Remission of Human Type 2 Diabetes Requires Decrease in Liver and Pancreas Fat Content but Is Dependent upon Capacity for β Cell Recovery: Cell Metabolism https://t.co/CmnwMEBzI2 Typ 2 Diabetes reversibel, wenn früh genug gehandelt wird.

Sep 20, 2019 · 1 like · 3,026 followers View post →

All mentions

Michigan Buckeye
@UMich_Buckeye · X

@otrbikers @Lilgang16 @brainaddiction Finally, just to throw you a bone, here is a study on your T2D point just for fun. Roy Taylor's group tried your idea, diet/weight loss for EARLY (not advanced T2D). Guess what, 46% of folks got their A1c to the non-diabetic range. https://t.co/x5aKxfr0jO

Feb 19, 2025 · 1,560 followers View post →
thoroughlyconfused
@thoroughlyconf1 · X

@zupanc_tadej @dylanarmbruste3 @theproof @ChrisMasterjohn I'm not sure what you are asking. TGs in plasma and % liver fat are different metrics (though they both generally correlate with severity of IR). Here's the cited study. Figure 4. https://t.co/SUSlTGgXGy https://t.co/Qv9l9AR5rS

Dec 5, 2024 · 62 followers View post →
Harmless Frog
@FrogHarmless · X

@raphaels7 @tednaiman https://t.co/Rid8hynZVK https://t.co/7vbPMhyi1z

May 5, 2024 · 2 likes · 502 followers View post →
Stellasternchen
@Stellaster20290 · X

@BHBEnjoyer @realDaveFeldman @AlexJLeaf @tednaiman Diabetes type 2 remission depends on the ability of the ß-cells of the pancreas to recover, not on fat cells quality. The loss of pancreas function is what leads to uncontrolled blood sugar and impaired glucose tolerance. https://t.co/Ysrj2vYi92

Mar 25, 2024 · 1 like · 1 followers View post →
Vishal Mishra
@sitgvish · X

RT @Mangan150: Remission of Human Type 2 Diabetes Requires Decrease in Liver and Pancreas Fat Content but Is Dependent upon Capacity for be…

Jan 7, 2024 · 1 share · 445 followers View post →
P.D. Mangan Health & Freedom Maximalist
@Mangan150 · X

Remission of Human Type 2 Diabetes Requires Decrease in Liver and Pancreas Fat Content but Is Dependent upon Capacity for beta Cell Recovery But is it really? The non-responders did not lose as much weight and remained obese. That's the big difference. https://t.co/b49Mn8Fkeh

Jan 7, 2024 · 26 likes · 1 share · 294,719 followers View post →
Kevin Harris
@kevtharris · X

@shelly_187 https://t.co/jLKcoT8P8j

Oct 13, 2023 · 545 followers View post →
جابر الهذلي
@jaberdadi · X

Remission of Human Type 2 Diabetes Requires Decrease in Liver and Pancreas Fat Content but Is Dependent upon Capacity for β Cell Recovery. https://t.co/QOICwlHEiB

Sep 21, 2023 · 5,580 followers View post →
Shnauser
@Shnauser1 · X

@iboprof @SueBeac44108054 @Inversionism @robertkelsch7 This study demonstrates that β cell ability to recover long-term function persists after diagnosis, changing the previous paradigm of irreversible loss of β cell function in type 2 diabetes. https://t.co/ya5uRJFuGC

Aug 27, 2023 · 885 followers View post →
Alex Leaf
@AlexJLeaf · X

Importantly, a secondary analysis of the DiRECT trial found, once again, that T2DM reversal will occur in only those whose pancreas is able to resume normal functionality and insulin secretion ability. https://t.co/I4qRsZbXVF

Jan 22, 2023 · 10 likes · 4,410 followers View post →
S B
@Conigman · X

@squeeshymeeshy @MetabolicSafe @nicknorwitz With all due respect, i will take the advice of a professor whose specialty is in T2D https://t.co/iOEPQ1oHi5

Sep 18, 2022 · 1,259 followers View post →
Adam Jaworski
@adam__jaworski · X

@lekarzsuwala @LeskiPiotr @MagdalenaOTR NIE. Mowa tu o 46% ludzi z grupy eksperym. po diagnozie cukrzycy T2 do 6 lat. Niewykluczone, że okres może być dłuższy w konkretnych przypadkach. Zależne od "stanu" komórek β trzustki, ale precyzyjne punkty odcięcia - wciąż niezdefiniowane... https://t.co/k1y24opoj7 https://t.co/3kQe4RjdG5

May 8, 2022 · 2 likes · 84 followers View post →
Nutrem
@MxNutrem · X

Cualquier dieta que te haga perder grasa abdominal y por ende del hígado y páncreas, va a propiciar un restablecimiento de funciones de las células beta y por ende una remisión de la diabetes. No es que la carne per se cure la diabetes. https://t.co/rGolcDCY9l https://t.co/Bj4n3amrQR

Mar 24, 2022 · 259 followers View post →
Das
@ssdas29 · X

Revisiting DiRECT trial 1)Remission of Human Type 2 Diabetes Requires Decrease in Liver and Pancreas Fat Content but Is Dependent upon Capacity for β Cell Recovery (10.1016/j.cmet.2018.07.003 )

Jun 14, 2021 · 392 followers View post →
TheNutritionNetwork
@NutritionNetwor · X

RT @BANTonline: How did SACN ignore fatty liver in type 2 diabetes ? https://t.co/WNpxqlsl3P

Apr 14, 2020 · 1 share · 2,799 followers View post →
BANT
@BANTonline · X

How did SACN ignore fatty liver in type 2 diabetes ? https://t.co/WNpxqlsl3P

Apr 14, 2020 · 8 likes · 1 share · 7,663 followers View post →
NIG
@dr_med_ivanhoe · X

Remission of Human #Type2Diabetes Requires Decrease in #Liver and #Pancreas Fat Content but Is Dependent upon Capacity for #βCell Recovery https://t.co/HeQbvNtRIQ | via @Cell_Metabolism

Jan 3, 2020 · 479 followers View post →
RxRealm
@RxRealm · X

New Blog Post: Remission of human Type 2 diabetes requires decrease in liver and pancreas fat content but is dependent upon capacity for B cell recovery - (Source: CrossFit) https://t.co/UXziaWucGw

Dec 18, 2019 · 151 followers View post →
RxRealm
@RxRealm · X

Remission of human Type 2 diabetes requires decrease in liver and pancreas fat content but is dependent upon capacity for B cell recovery - [Source: CrossFit] https://t.co/UXziaWucGw #article #athlete #blog #crossfit #crossfitarticle #crossfitblog #crossfitnews #essentials #f... https://t.co/ZeElm6JmEn

Dec 18, 2019 · 151 followers View post →
Tony Larkman
@tonylarkman · X

Proof that Type 2 Diabetes is reversible. Remission of Human Type 2 Diabetes Requires Decrease in Liver and Pancreas Fat Content but Is Dependent upon Capacity for β Cell Recovery #personaltrainer #fitness #diabetes #type2diabetes #health #diet https://t.co/DIDdNPVb5P

Sep 29, 2019 · 325 followers View post →
Mark Maslow
@MarkMaslow · X

Remission of Human Type 2 Diabetes Requires Decrease in Liver and Pancreas Fat Content but Is Dependent upon Capacity for β Cell Recovery: Cell Metabolism https://t.co/CmnwMEBzI2 Typ 2 Diabetes reversibel, wenn früh genug gehandelt wird.

Sep 20, 2019 · 1 like · 3,026 followers View post →
ENDALA klinika zdraví
@endalaclinic · X

Remission of Human Type 2 Diabetes Requires Decrease in Liver and Pancreas Fat Content but Is Dependent upon Capacity for β Cell Recovery: Cell Metabolism https://t.co/7HZtOQrigF

Sep 12, 2019 · 252 followers View post →
Alexei Stavroguine
@AlexStavroguine · X

@CitronAlcalin @keskonsamuz @BayesReality Une étude postérieur à confirmé la "rémission", réversibilité du diabète de type 2 à la condition qu'il n'y ait pas de perte de fonction irréversible des cellules du pancréas productrices d’insuline. https://t.co/szgKuKnigp

Jan 14, 2019 · 1,504 followers View post →