October 2018 PMID 30102953

Fatty acid oxidation: An emerging facet of metabolic transformation in cancer.

Yibao Ma, Sarah M Temkin, Adam M Hawkridge, Chunqing Guo, Wei Wang, Xiang-Yang Wang, Xianjun Fang

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Mentions

5
Peak: 1 in Apr 2023
across 3 sources since Apr 2023

Extended reach

77,969
potential audience

Total likes

3,623

Video views

77,859

Mentions per month

Apr 2023 – Nov 2023

Where it's discussed

  • YouTube2 videos
  • Blogs2 articles
  • X / Twitter1 posts

AI synopsis

What people are saying

The analysis highlights the importance of FAO in cancer cells, emphasizing shifts toward lactate production over pyruvate, which reflects a focus on metabolic reprogramming. Words like 'important' and references to specific pathways suggest a moderate level of engagement and interest, with recognition of the potential implications of these metabolic insights for cancer therapy.

AgreementModerate agreement

The discussion recognizes the importance of fatty acid oxidation (FAO) in cancer metabolism, aligning with the article's focus.

InterestModerate interest

The post indicates curiosity about metabolic pathways in cancer cells but remains somewhat limited in scope.

EngagementNeutral engagement

The discussion is somewhat superficial, mentioning key points like lactate production and FAO without delving into detailed mechanisms or implications.

ImpactModerate impact

The post highlights the significance of the metabolic shift in cancer, suggesting the findings could influence future research or treatment strategies.

Abstract in brief

  • Cancer cells reprogram their metabolism by increasing processes like glycolysis, lipid synthesis, and glutaminolysis to survive in harsh environments and support growth.
  • Recent research shows that fatty acid oxidation (FAO), a key energy source in normal cells, is also crucial in cancer development, aiding in proliferation, survival, and metastasis.
  • The article explores how FAO is reprogrammed in cancer and immune cells, contributing not only to tumor growth but also presenting potential new targets for cancer therapy.]

Top posts

Most liked on X and Bluesky
K-2
@boioyong · X

@bronzeagemantis The mere fact that fructose can be used as a substrate for cancer cells doesn’t prove anything at all. The important thing is that cancer cells are shifted towards lactate production from sugars (instead of pyruvate) and FAO. https://t.co/rDiFh8RSDn

Nov 12, 2023 · 4 likes · 110 followers View post →

All mentions

Understanding Cancer as a Metabolic Disorder

Cancer is increasingly viewed as a metabolic disorder, suggesting that abnormal metabolism in cancer cells might be a primary cause. Key metabolic changes such as disruptions in glucose and fatty acid metabolism could…

Physionic · Jun 19, 2023 75,585 views
K-2
@boioyong · X

@bronzeagemantis The mere fact that fructose can be used as a substrate for cancer cells doesn’t prove anything at all. The important thing is that cancer cells are shifted towards lactate production from sugars (instead of pyruvate) and FAO. https://t.co/rDiFh8RSDn

Nov 12, 2023 · 4 likes · 110 followers View post →