Does anyone in #GItwitter have any clinical experience using L-Glutamine supplements to manage #diarrhea and/or #IBS? I found one small study published in 2018 with surprisingly interesting results, https://t.co/V9okjGjxft
Randomised placebo-controlled trial of dietary glutamine supplements for postinfectious irritable bowel syndrome.
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Jul 2021 – Jul 2025Where it's discussed
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X / Twitter14 posts
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News14 articles
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Facebook8 posts
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Blogs5 articles
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YouTube4 videos
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Reddit3 posts
AI synopsis
What people are saying
The digital discussions reflect an overall positive reception of the study, with users referencing its promising results, such as citing that glutamine 'dramatically and safely reduced all major IBS-related endpoints,' and expressing interest in larger clinical trials. The tone and choice of words like 'interesting,' 'spans,' 'showed,' and 'should be pursued' convey curiosity and a recognition of the study's potential importance, contributing to the moderate scores across all dimensions.
Most discussions recognize the positive findings of the study, highlighting the potential benefits of glutamine for post-infectious IBS.
Participants show moderate curiosity, referencing specific studies and potential clinical applications, indicating a genuine interest.
Several comments delve into the mechanisms, previous research, and implications, demonstrating a thoughtful engagement with the topic.
The discussions suggest that if validated, the research could influence clinical approaches to managing IBS, indicating a modest but meaningful impact.
Abstract in brief
- This study tested whether oral glutamine supplements can help patients with post-infectious irritable bowel syndrome (IBS) who experience diarrhea and increased intestinal permeability, finding that glutamine significantly improved symptoms, bowel habits, stool consistency, and gut permeability compared to a placebo over 8 weeks.
- The trial involved 54 patients taking glutamine and 52 taking a placebo, with results showing that 43% of the glutamine group had a major reduction in IBS severity versus only 3% in the placebo group, and glutamine also improved secondary measures like stool form and intestinal permeability with minimal side effects.
- The researchers suggest that glutamine, which appears to restore gut barrier function and reduce IBS symptoms safely, warrants larger clinical trials to confirm benefits, understand how it works, and evaluate impacts on patients’ quality of life.]
Top posts
Most liked on X and Bluesky#Glutamin könnte bei #RDS-PI hilfreich sein, zeigt kleine Studie. Spannender Ansatz, der weiterverfolgt werden sollte! Randomised placebo-controlled trial of dietary glutamine supplements for postinfectious irritable bowel syndrome | Gut https://t.co/b6G1FScY8p
@angryhacademic In a dysmetabolic state proteins can be used as fuel for mitochondrial energy, carnitin is one important part in this. In addition glutamine has been discussed for improvement of gut health after infections and irritable Bowle syndrome. https://t.co/I8vk5ujnCM
@DrNeilStone NEVER? "All those...."? Your gross generalizations are both hyperbolic & misleading. At least try to be honest, accurate & trustworthy in your science communication efforts. Creatine https://t.co/0y2hNJPNEV Glutamine https://t.co/R6qHpmg2OG EAAs https://t.co/0NQETou7o8
@Gilbro2010 Intéressant. Tu peux essayer en attenant la L-Glutamine qui réduit la perméabilité intestinale. https://t.co/NutXpgV2Ek https://t.co/0n2tCZcJBH https://t.co/LVhFCRDCIx
Hicieron un buen cribado antes del estudio, descartando SIBO, celiaquía, EII, enfermedad hepática, pancreatitis, etc. Aunque el autoregistro de síntomas siempre tendrá sus limitaciones. Referencia: https://t.co/GTyVtkjGYO
All mentions
Glutamine Benefits for Immune Health and Metabolic Balance
Let's talk about the benefits of glutamine supplement. In this video, I share how I supplement glutamine, its benefits, and why it's a valuable nutrient. As a naturopathic doctor, I frequently recommend and use…
Combining Glutamine and FODMAP Reduction Enhances IBS Relief
This video discusses a recent study demonstrating that combining Glutamine supplementation with a low FODMAP diet can reduce IBS symptoms by up to 23%. It explores the effectiveness of these treatments and their…
Glutamine Supplementation for Post-Infectious Irritable Bowel Syndrome
This video discusses how dietary glutamine can significantly improve symptoms, bowel habits, and intestinal permeability in patients with post-infectious IBS, based on recent clinical trial findings.
Glutamine's Role in Managing Postinfectious IBS Symptoms Effectively
This study examines the effectiveness of oral glutamine supplements in improving symptoms, bowel habits, and gut permeability in post-infectious IBS patients over 8 weeks, highlighting significant symptom reduction and…
@Gilbro2010 Intéressant. Tu peux essayer en attenant la L-Glutamine qui réduit la perméabilité intestinale. https://t.co/NutXpgV2Ek https://t.co/0n2tCZcJBH https://t.co/LVhFCRDCIx
Referências: https://t.co/4mQOSilpTp
@DrNeilStone NEVER? "All those...."? Your gross generalizations are both hyperbolic & misleading. At least try to be honest, accurate & trustworthy in your science communication efforts. Creatine https://t.co/0y2hNJPNEV Glutamine https://t.co/R6qHpmg2OG EAAs https://t.co/0NQETou7o8
RT @IBSpatient: Does anyone in #GItwitter have any clinical experience using L-Glutamine supplements to manage #diarrhea and/or #IBS? I fou…
RT @IBSpatient: Does anyone in #GItwitter have any clinical experience using L-Glutamine supplements to manage #diarrhea and/or #IBS? I fou…
Does anyone in #GItwitter have any clinical experience using L-Glutamine supplements to manage #diarrhea and/or #IBS? I found one small study published in 2018 with surprisingly interesting results, https://t.co/V9okjGjxft
Conclusions: In patients with IBS-D with intestinal hyperpermeability following an enteric infection, oral dietary glutamine supplements dramatically and safely reduced all major IBS-related endpoints. Large randomised clinical trials (RCTs) should .." https://t.co/XNrJkk3DqL
@angryhacademic In a dysmetabolic state proteins can be used as fuel for mitochondrial energy, carnitin is one important part in this. In addition glutamine has been discussed for improvement of gut health after infections and irritable Bowle syndrome. https://t.co/I8vk5ujnCM
RT @TomKindlon: "Randomised placebo-controlled trial of dietary glutamine supplements for postinfectious #IrritableBowelSyndrome" "Oral di…
RT @SchillingBea: #Glutamin könnte bei #RDS-PI hilfreich sein, zeigt kleine Studie. Spannender Ansatz, der weiterverfolgt werden sollte! Ra…
RT @SchillingBea: #Glutamin könnte bei #RDS-PI hilfreich sein, zeigt kleine Studie. Spannender Ansatz, der weiterverfolgt werden sollte! Ra…
#Glutamin könnte bei #RDS-PI hilfreich sein, zeigt kleine Studie. Spannender Ansatz, der weiterverfolgt werden sollte! Randomised placebo-controlled trial of dietary glutamine supplements for postinfectious irritable bowel syndrome | Gut https://t.co/b6G1FScY8p
@DidrikSoderlind @CTviberg her har dere litt om en av de mest mobbede helsetilstander, fordi det ikke passer inn i evidensialistkultens tvangspregede tankemønster. aka kontroversielt. kål er ikke sunt, for alle, men for de fleste. kål er imidlertid rikt på bla glutamin: https://t.co/XNrJkklePl
Hicieron un buen cribado antes del estudio, descartando SIBO, celiaquía, EII, enfermedad hepática, pancreatitis, etc. Aunque el autoregistro de síntomas siempre tendrá sus limitaciones. Referencia: https://t.co/GTyVtkjGYO