August 2018 PMID 30139444

Midlife Cardiorespiratory Fitness and the Long-Term Risk of Mortality: 46 Years of Follow-Up.

Johan S R Clausen, Jacob L Marott, Andreas Holtermann, Finn Gyntelberg, Magnus T Jensen

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Mentions

174

Peak: 23 in Aug 2021

across 5 sources since Sep 2019

Extended reach

442,634

potential audience

Total likes

3,369

Video views

135,755

Mentions per month

Sep 2019 – Aug 2025

Where it's discussed

News98 articles
X / Twitter56 posts
Facebook10 posts
Blogs6 articles
YouTube4 videos

AI synopsis

What people are saying

Overall, discussions show strong agreement with the study’s conclusions, with many posts citing specific figures like 'living about five years longer' or 'each unit increase in VO2max adds 45 days,' emphasizing the significance of fitness for longevity. The tone is inquisitive and supportive, emphasizing the potential health benefits while acknowledging some debates about data variability and robustness.

AgreementModerate agreement

Most discussions acknowledge and support the findings of the study, emphasizing the positive correlation between higher cardiorespiratory fitness and longevity.

InterestHigh interest

Posts demonstrate high interest by referencing specific data, such as years of extra lifespan and health benefits, and sharing related studies.

EngagementModerate engagement

Participants engage meaningfully through questions about reconciling data, sharing personal insights, and referencing scientific analyses, showing active involvement.

ImpactModerate impact

The conversations reflect a moderate impact, with discussions about practical implications for health and lifespan, though some skepticism and debates about data robustness exist.

Abstract in brief

The study followed over 5,000 middle-aged men in Copenhagen for 46 years and found that higher cardiorespiratory fitness (CRF) in midlife is strongly associated with longer life expectancy and lower risk of death from all causes and cardiovascular disease.
Men with CRF levels below normal had an average of 21 years of increased lifespan, whereas those with high normal or above-normal CRF could live up to nearly 50 more years, and each unit increase in CRF added about 45 days to lifespan.
The results remained consistent even when considering only those who survived the first 10 years, indicating that the relationship between better CRF and increased longevity is unlikely to be influenced by reverse causation or early illness.]

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All mentions

Maximizing VO2 Max for Enhanced Fat Loss and Longevity

This video explores effective strategies to increase VO2 max, vital for fat loss and longevity. Learn about the best types of exercise, including HIIT and the Norwegian 4x4 method, to boost your cardiorespiratory…

Thomas DeLauer · Mar 5, 2025 104,831 views

Impact of Cardiorespiratory Fitness on Long-Term Mortality

This video explores the relationship between cardiorespiratory fitness and mortality risk. It discusses key findings from a 46-year study, highlighting how midlife fitness levels can predict long-term health outcomes…

Physionic · Jan 15, 2025 30,011 views

Exploring VO2 Max as a Predictor of Longevity and Health

Your VO2 Max is a key indicator for longevity, correlating with overall health. This video discusses how cardiorespiratory fitness, linked to exercise, impacts your lifespan and quality of life.

Brandon Lewis NP · Sep 25, 2024 894 views

Assessing Cardiorespiratory Fitness for Long-Term Health

The Physical Activity Guidelines support a process for long-term health. This video covers accessible methods to measure your cardiorespiratory fitness, providing milestones to guide your lifelong fitness journey…

Trauma-Informed Exercise + Nutrition · Nov 5, 2024 20 views

Zach Zenner

@zenner31 · X

I'm 16% less likely to die after one month of VO2 max training. Seriously. Here are a couple studies: https://t.co/R6QS43WTQa https://t.co/08zdbw5nbW The issue is that VO2 Max is a fluid metric, so just as easily as it went up, it can go down. This means that my life https://t.co/598UdXb2Ph

Aug 29, 2025 · 3 likes · 11,475 followers View post →

blubber_bones

@blubber_bones · X

The Easiest Way to Increase Vo2 Max for Fat Loss and Longevity (with exe... https://t.co/C2P6vhHZC3 via @YouTube

Mar 5, 2025 · 1,079 followers View post →

jlscwrokout

@jlscworkout · X

Kodama et al.'s meta-analysis showed a 13% reduction in all-cause mortality for every 1 metabolic unit increase in aerobic capacity. Improve your metabolic performance with the Sugar Kane Workout at https://t.co/io02JFFKk9. Source: https://t.co/oc7nRyXiG4

Oct 24, 2024 View post →

Dr. Zain | RiverRock Medical

@DrZainHakeem · X

@ZKForTre To answer your question, not super robust. Here is the most relevant paper: Midlife VO2 max was an excellent predictor of mortality after 40+ years of followup. The authors were specifically concerned about reverse causality. https://t.co/rTeqSqf6aT

Sep 9, 2024 · 81 followers View post →

Andrés Logroño

@AndrsLogrono · X

La aptitud cardiorrespiratoria se relacionó significativamente con longevidad a lo largo de cuatro décadas en hombres de mediana edad, empleados y sin ECV. Los beneficios de un CRF más alto en la mediana edad se extienden hasta la última parte de la vida. https://t.co/DpAGSEDnI0

Aug 27, 2024 · 1 like · 1,312 followers View post →

Alisa Saleh, MD

@DrAlisaSaleh · X

Source: https://t.co/QFoaFMHm3w

Aug 23, 2024 · 23 followers View post →

claude shannon

@catpoopburglar · X

@keccers the problem is the data is the data https://t.co/CquGGLvJrr people with higher VO2Max’s are less likely to die

Jul 10, 2024 · 2 likes · 2,460 followers View post →

dennis

@dennismuellr · X

@celestialbe1ng how do you reconcile that with vo2max predicting life expectancy? https://t.co/dvwfrNBH0S.

Jun 23, 2024 · 4 likes · 19,096 followers View post →

Justin Wheeler

@wheelerjustin · X

@foundmyfitness For those saying this is bullshit here's a reasonable looking study that suggestscthere is a syrongbcirrelation between vo2 max and longevity: https://t.co/rm6jN2x8Km

Apr 23, 2024 · 1 like · 2,686 followers View post →

Dr Sam Pappas

@DrSamPappas · X

RT @mike_lustgarten: Midlife Cardiorespiratory Fitness and the Long-Term Risk of Mortality: 46 Years of Follow-Up https://t.co/Krj3OvnEsT

Mar 10, 2024 · 5 shares · 2,089 followers View post →

Mind Your Science!

@MindYourSci · X

RT @agingdoc1: Midlife Cardiorespiratory Fitness and the Long-Term Risk of Mortality: 46 Years of Follow-Up https://t.co/ARGcJLDVQi CRF w…

Mar 7, 2024 · 1 share · 133 followers View post →

Ralph Bennett

@RBennettIV · X

RT @mike_lustgarten: Midlife Cardiorespiratory Fitness and the Long-Term Risk of Mortality: 46 Years of Follow-Up https://t.co/Krj3OvnEsT

Mar 7, 2024 · 5 shares · 362 followers View post →

Manoj Mayogi Mishra

@mayogisense · X

RT @mike_lustgarten: Midlife Cardiorespiratory Fitness and the Long-Term Risk of Mortality: 46 Years of Follow-Up https://t.co/Krj3OvnEsT

Mar 7, 2024 · 5 shares · 572 followers View post →

Mesha

@cosmautic · X

RT @mike_lustgarten: Midlife Cardiorespiratory Fitness and the Long-Term Risk of Mortality: 46 Years of Follow-Up https://t.co/Krj3OvnEsT

Mar 6, 2024 · 5 shares · 456 followers View post →

Mike Lustgarten, PhD

@mike_lustgarten · X

Midlife Cardiorespiratory Fitness and the Long-Term Risk of Mortality: 46 Years of Follow-Up https://t.co/Krj3OvnEsT

Mar 6, 2024 · 19 likes · 5 shares · 9,722 followers View post →

Agingdoc

@agingdoc1 · X

Midlife Cardiorespiratory Fitness and the Long-Term Risk of Mortality: 46 Years of Follow-Up

Mar 6, 2024 · 6 likes · 41,316 followers View post →

Nick

@Cellthyhomes · X

Midlife Cardiorespiratory Fitness ..Over 5000 participants 46 Years of Follow-Up from the Journal of the American College of Cardiology https://t.co/jqKTHgrOf5

Feb 26, 2024 · 189 followers View post →

mark anselmo

@McCrossCheck · X

@FitFounder @dstaples https://t.co/Y3QmuyVj0U totally agree that higher cardio resp fitness will add years, but your lookin at about +4y on average with a very high vo2 max. (Btw my lab does these studies, cycle and treadmill) Good luck on beating 100. I won’t be around

Dec 28, 2023 · 887 followers View post →

miSIXeWay Fastfood

@miSIXeWay · X

In seeking a longer #healthspan, your #cardiorespiratory #fitness (#CRF) could increase life expectancy from 2.1 yrs to over 4.9 yrs. “Each unit increase in #Vo2max was associated with a 45-day increase in longevity.” From https://t.co/yGnlZ5fWar via https://t.co/xNhvzE63Nr https://t.co/u7MNPh9kqY

Nov 22, 2023 · 1 like · 5 followers View post →

michael r barrett

@zaailor · X

.@cindykuzma reports

Nov 22, 2023 · 1 like · 103 followers View post →

Thiago Guimarães Osório

@ThiagoOso · X

@theproof You might want to check out this study! https://t.co/koZDFz29jw "participants in the highest five percent range of VO2max lived about five years longer than those in the bottom five percent." https://t.co/b3S47nKk0N

May 26, 2022 · 1 like · 20 followers View post →

Simon Hill MSc, BSc

@theproof · X

@fulvioguerra https://t.co/E0EH775DAA

May 24, 2022 · 34,070 followers View post →

LauraNoEsta

@Gaalleetta · X