Biochem Soc Trans October 2018 PMID 30190332

The discovery of hydrogen bonds in DNA and a re-evaluation of the 1948 Creeth two-chain model for its structure.

Stephen E Harding, Guy Channell, Mary K Phillips-Jones

Mentions

26
Peak: 11 in May 2020
across 4 sources since May 2020

Extended reach

787,142
potential audience

Total likes

7,374

Video views

603,462

Mentions per month

May 2020 – Nov 2024

Where it's discussed

  • X / Twitter19 posts
  • YouTube3 videos
  • Facebook2 posts
  • Blogs2 articles

AI synopsis

What people are saying

The discussions reveal a respectful appreciation for the historical significance of Michael Creeth's model and hydrogen bonds, with examples such as references to the Nottingham involvement in DNA discovery and mentions of foundational concepts like 3D molecular structures. The tone balances admiration with educational insights, reflecting moderate engagement and acknowledgment of the research's impact on the field.

AgreementModerate agreement

Most comments support the importance of historical DNA models and recognize the significance of hydrogen bonds, with some explicitly praising or referencing the discovery's impact.

InterestModerate interest

Discussions show curiosity about the historical context and relevance of the research, indicating moderate interest rather than extensive engagement.

EngagementModerate engagement

Posts occasionally reference related concepts like DNA structure and hydrogen bonding mechanisms, demonstrating some depth, but not highly detailed or technical conversations.

ImpactModerate impact

There is a shared view that the discovery and re-evaluation of the 1948 model contribute meaningfully to understanding DNA's structure, though some comments are more reflective or educational.

Abstract in brief

  • The text reviews the historical discovery of hydrogen bonds in DNA by researchers at University College Nottingham led by JM Gulland, which was a crucial step in understanding DNA's double-helix structure, though early studies couldn't distinguish between inter- and intrachain bonds.
  • It discusses a 1948 model proposed by Gulland and JD Creeth, which accurately predicted DNA's two-chain structure with a sugar-phosphate backbone on the outside and hydrogen-bonded bases inside, although Creeth's details about alternating breaks weren't necessary to explain experimental data.
  • The analysis highlights that Creeth’s model was purely structural since mechanisms of DNA replication weren’t known then, but it interestingly resembled some aspects of viral replication processes that involve hydrogen bonding and DNA's double-strand nature.]

Top posts

Most liked on X and Bluesky
CrashCourse
@TheCrashCourse · X

So far we’ve been using 2-D structures to represent organic molecules. But all of these compounds, from the simplest organic molecule to the most complex proteins, have 3-D shapes as well. And those 3-D shapes help us understand what they can do! https://t.co/ATdi9WvQzB https://t.co/foXs2KzPE9

May 27, 2020 · 38 likes · 9 shares · 162,331 followers View post →
Steve Harding
@Steve_E_Harding · X

Life Story Film & Nottingham's involvement in the Double Helix discovery... https://t.co/uxO63CGYmP via @YouTube @BishopSue @olwynbyron @BritBiophysSoc ..There's a nice epilogue! We show this every year to our Master's students in Biomolecular Technology. Link to film is given

Oct 7, 2022 · 6 likes · 1 share · 317 followers View post →
yuu_a_240327
@yuu_a_240327 · X

Nov 24, 2024 · 3 likes · 1 share · 1,648 followers View post →
Ejay
@realEJAB · X

I like how crash course credited Rosalind Franklin instead of W4tson and Cr1ck. https://t.co/z5HFYffz6I

Aug 12, 2020 · 1 like · 993 followers View post →
Complexly
@ComplexlyMedia · X

RT @TheCrashCourse: So far we’ve been using 2-D structures to represent organic molecules. But all of these compounds, from the simplest…

May 27, 2020 · 9 shares · 8,538 followers View post →
Marija Petreska
@teachermarija · X

New video by CrashCourse: 3D Structure and Bonding: Crash Course Organic Chemistry #4 https://t.co/0qNfecBzyk #EDCHAT #EDUCATION

May 27, 2020 · 3,501 followers View post →

All mentions

yuu_a_240327
@yuu_a_240327 · X

Nov 24, 2024 · 3 likes · 1 share · 1,648 followers View post →
Steve Harding
@Steve_E_Harding · X

#DNADay 25th April 2023: Unveiling of the Owen Epps Painting for the Creeth 1947/8 model for DNA https://t.co/sNnJiQNqcw (12 mins) https://t.co/sNnJiQNqcw (12 mins) @BritBiophysSoc @mayavision @BiochemSoc @CamBiochem @OxBiochem @WirralLibraries @NbsOslo @RoySocChem @AmChemistry

Apr 28, 2023 · 317 followers View post →
pancakeson
@pancakeson · X

RT @Steve_E_Harding: Life Story Film & Nottingham's involvement in the Double Helix discovery... https://t.co/uxO63CGYmP via @YouTube @Bish…

Oct 28, 2022 · 1 share · 639 followers View post →
Steve Harding
@Steve_E_Harding · X

Life Story Film & Nottingham's involvement in the Double Helix discovery... https://t.co/uxO63CGYmP via @YouTube @BishopSue @olwynbyron @BritBiophysSoc ..There's a nice epilogue! We show this every year to our Master's students in Biomolecular Technology. Link to film is given

Oct 7, 2022 · 6 likes · 1 share · 317 followers View post →
Thorsten Behrendt
@ThorteeDeluxe · X

https://t.co/ckMWC1OjTx

Mar 22, 2021 · 1,659 followers View post →
Tiago Henrique
@tiago35henrique · X

https://t.co/ViyAq3UBXZ

Sep 13, 2020 · 124 followers View post →
Ejay
@realEJAB · X

I like how crash course credited Rosalind Franklin instead of W4tson and Cr1ck. https://t.co/z5HFYffz6I

Aug 12, 2020 · 1 like · 993 followers View post →
YTMO News
@YtmoNews · X

RT @YtmoNews: 3D Structure and Bonding: Crash Course Organic Chemistry #4 https://t.co/jGd6QKd9aH

Jul 17, 2020 · 1 share · 25 followers View post →
YTMO News
@YtmoNews · X

3D Structure and Bonding: Crash Course Organic Chemistry #4 https://t.co/jGd6QKd9aH

Jun 17, 2020 · 1 share · 25 followers View post →
boxnos
@boxnos · X

見る! 3D Structure and Bonding: Crash Course Organic Chemistry #4 - YouTube https://t.co/LkKD2I2ZWs

May 29, 2020 · 166 followers View post →
Flavio de Paula
@fdeflavio · X

RT @TheCrashCourse: So far we’ve been using 2-D structures to represent organic molecules. But all of these compounds, from the simplest…

May 27, 2020 · 9 shares · 222 followers View post →
e-csce
@e_csce · X

3D Structure and Bonding: Crash Course Organic Chemistry #4 The organic molecules that make up life on Earth are more than just the 2-D structures we’ve been drawing so far. Molecules have 3-D shapes that help us understand what they can do. In this epi… https://t.co/0BVn7OoSy6 https://t.co/O90dr1QOPf

May 27, 2020 · 117 followers View post →
Complexly
@ComplexlyMedia · X

RT @TheCrashCourse: So far we’ve been using 2-D structures to represent organic molecules. But all of these compounds, from the simplest…

May 27, 2020 · 9 shares · 8,538 followers View post →
abishek sampath
@SampathAbishek · X

3D Structure and Bonding: Crash Course Organic Chemistry #4 https://t.co/y9QVdq7LRW

May 27, 2020 · 3 followers View post →
kick-ass ☁️
@FaletiJoshua · X

RT @TheCrashCourse: So far we’ve been using 2-D structures to represent organic molecules. But all of these compounds, from the simplest…

May 27, 2020 · 9 shares · 1,624 followers View post →
Ivy Tara Blair | audiobooks | sound engineer
@ivytarablair · X

RT @TheCrashCourse: So far we’ve been using 2-D structures to represent organic molecules. But all of these compounds, from the simplest…

May 27, 2020 · 9 shares · 422 followers View post →
so sane ☭
@sosane19 · X

RT @TheCrashCourse: So far we’ve been using 2-D structures to represent organic molecules. But all of these compounds, from the simplest…

May 27, 2020 · 9 shares · 892 followers View post →
CrashCourse
@TheCrashCourse · X

So far we’ve been using 2-D structures to represent organic molecules. But all of these compounds, from the simplest organic molecule to the most complex proteins, have 3-D shapes as well. And those 3-D shapes help us understand what they can do! https://t.co/ATdi9WvQzB https://t.co/foXs2KzPE9

May 27, 2020 · 38 likes · 9 shares · 162,331 followers View post →
Marija Petreska
@teachermarija · X

New video by CrashCourse: 3D Structure and Bonding: Crash Course Organic Chemistry #4 https://t.co/0qNfecBzyk #EDCHAT #EDUCATION

May 27, 2020 · 3,501 followers View post →