PubHawk
May 2019 PMID 30221610

Genetic influences on eight psychiatric disorders based on family data of 4 408 646 full and half-siblings, and genetic data of 333 748 cases and controls.

E Pettersson, P Lichtenstein, H Larsson, J Song, A Agrawal, A D Børglum, C M Bulik, M J Daly, L K Davis, D Demontis, H J Edenberg, J Grove, J Gelernter, B M Neale

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Mentions

17
Peak: 2 in Jul 2019
across 4 sources since Jun 2019

Extended reach

19,521
potential audience

Total likes

409

Video views

9,921

Mentions per month

Jun 2019 – Oct 2025

Where it's discussed

  • News8 articles
  • X / Twitter5 posts
  • YouTube2 videos
  • Blogs2 articles

AI synopsis

What people are saying

The overall discussions show a strong engagement with the study, using technical terms such as 'heritability estimates' and 'genetic influences,' indicating a keen interest in both its scientific details and broader implications for psychiatric research, with some comments like questioning findings in controls adding depth to the dialogue.

AgreementModerate agreement

Most discussions acknowledge the importance and relevance of the study, with some questioning the nuances of heritability findings.

InterestHigh interest

Posts demonstrate high interest in the research’s implications for understanding psychiatric genetics.

EngagementModerate engagement

Participants reference specific concepts like heritability estimates, methodology, and genetic factors actively engaging with the content.

ImpactModerate impact

Discussions highlight the potential influence of the findings on future research and the understanding of psychiatric disorders.

Abstract in brief

  • The study analyzes the genetic contribution to eight psychiatric disorders using two different research methods—family data from Swedish siblings and genetic data from cases and controls—finding that heritability estimates vary but are generally consistent across methods.
  • Heritability estimates ranged from 0.10 for alcohol dependence to 0.80 for ADHD in sibling data, while genotype-based estimates were lower but still significantly positive, showing a positive correlation between the methods.
  • The results demonstrate that, despite differences in study design, heritability estimates are generally robust, and there are notable differences in genetic and environmental influences among these psychiatric conditions, guiding future research directions.
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Top posts

Most liked on X and Bluesky
CapiceProject
@capice_project · X

The latest paper on "Genetic influences on eight psychiatric disorders based on family data and genetic data" @capice_project https://t.co/NTVyD09uH1 @MSCActions @GamianE @EU_H2020 #InvestEUresearch #heritability #psychiatricdisorders #nationalsiblingdesign, #SNPbaseddesign https://t.co/LOi66M27BK

Jun 21, 2019 · 8 likes · 2 shares · 730 followers View post →
Global Alliance of Mental Illness Advocacy Network
@GAMIAN_Europe · X

RT @capice_project: The latest paper on "Genetic influences on eight psychiatric disorders based on family data and genetic data" @capice_p…

Jul 2, 2019 · 2 shares · 4,257 followers View post →
Psicólogo Celestino González-Fernández ψ
@Tecnoestres · X

#Genetic influences on eight psychiatric disorders based on family data of 4 408 646 full and half-siblings, and genetic data of 333 748 cases and controls @CambridgeUP #CGFPsicología https://t.co/fNCNWdNYUA

Jan 20, 2023 · 2,909 followers View post →
Topher Hübel
@topherhuebel · X

@PsychoanaMainz @PGCgenetics @NatureGenet Doch ist es, weil psychiatrische Störungen dann auch in den Kontrollen auftreten Hier die Studien zum genetischen "p factor": https://t.co/I0vbcHV7Y4 & https://t.co/RkXMTUPwPl

Aug 31, 2019 · 1,665 followers View post →

All mentions

Psicólogo Celestino González-Fernández ψ
@Tecnoestres · X

#Genetic influences on eight psychiatric disorders based on family data of 4 408 646 full and half-siblings, and genetic data of 333 748 cases and controls @CambridgeUP #CGFPsicología https://t.co/fNCNWdNYUA

Jan 20, 2023 · 2,909 followers View post →
Topher Hübel
@topherhuebel · X

@PsychoanaMainz @PGCgenetics @NatureGenet Doch ist es, weil psychiatrische Störungen dann auch in den Kontrollen auftreten Hier die Studien zum genetischen "p factor": https://t.co/I0vbcHV7Y4 & https://t.co/RkXMTUPwPl

Aug 31, 2019 · 1,665 followers View post →
Marina Carpena
@marina_carpena · X

RT @capice_project: The latest paper on "Genetic influences on eight psychiatric disorders based on family data and genetic data" @capice_p…

Jul 23, 2019 · 2 shares · 27 followers View post →
Global Alliance of Mental Illness Advocacy Network
@GAMIAN_Europe · X

RT @capice_project: The latest paper on "Genetic influences on eight psychiatric disorders based on family data and genetic data" @capice_p…

Jul 2, 2019 · 2 shares · 4,257 followers View post →
CapiceProject
@capice_project · X

The latest paper on "Genetic influences on eight psychiatric disorders based on family data and genetic data" @capice_project https://t.co/NTVyD09uH1 @MSCActions @GamianE @EU_H2020 #InvestEUresearch #heritability #psychiatricdisorders #nationalsiblingdesign, #SNPbaseddesign https://t.co/LOi66M27BK

Jun 21, 2019 · 8 likes · 2 shares · 730 followers View post →