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Neurology November 2018 PMID 30355700

Circulating cortisol and cognitive and structural brain measures: The Framingham Heart Study.

Justin B Echouffo-Tcheugui, Sarah C Conner, Jayandra J Himali, Pauline Maillard, Charles S DeCarli, Alexa S Beiser, Ramachandran S Vasan, Sudha Seshadri

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Mentions

223
Peak: 5 in Oct 2019
across 6 sources since Oct 2019

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95,890
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Oct 2019 – Sep 2025

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AI synopsis

What people are saying

The collective discussions show strong interest in the connection between cortisol and brain health, with mentions of stress impacting cognition and comments like 'Chronic stress impacts our brains' and 'The mechanism is high cortisol levels,' illustrating both concern and curiosity. The tone varies from supportive to contemplative, reflecting engagement with the significance of the research findings.

AgreementModerate agreement

Many discussions acknowledge and support the findings linking cortisol to cognitive and brain changes, indicating general agreement.

InterestHigh interest

The topics of stress, cortisol, and brain health evoke strong interest, as seen in comments emphasizing implications for mental health.

EngagementModerate engagement

Posts reference specific mechanisms and the significance of the findings, suggesting active engagement, yet mostly at a surface level.

ImpactModerate impact

There is recognition of the study's importance in understanding stress-related health issues, though concrete applications aren't deeply discussed.

Abstract in brief

  • The study found that higher early morning serum cortisol levels are linked to worse memory, visual perception, and reduced brain volumes, especially in women.
  • Elevated cortisol was also associated with microstructural brain changes, such as decreased integrity in specific white matter areas.
  • The relationship between cortisol and brain health appears to differ by sex, with women showing a stronger negative association between high cortisol and brain volume.]
Read the full abstract

Top posts

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Sara (Rest)
@SaraBangtan07 · X

Source: https://t.co/SxSGzDA5p4

Sep 14, 2025 · 19 likes · 1 share · 21,823 followers View post →
Cynthia Thurlow, NP
@_CynthiaThurlow · X

Chronic stress impacts our brains in negative ways..and can impact cognitive function significantly https://t.co/smwWy4IYBC

Jun 7, 2021 · 8 likes · 1 share · 56,094 followers View post →
@AdaraAstin@smutlandia.com is not here: see Pin
@AdaraAstin · X

@rche_types Me, too. The mechanism (at least partly) is high cortisol levels from the relentless high stress impair cognitive function. https://t.co/6b5IjrCp0x

May 22, 2022 · 2 likes · 1 share · 508 followers View post →
Mahmoud Abdelwahed
@MahmoudAwahed1 · X

@HossamBegovic @amr_sugar البحث كامل خدلك فكرة https://t.co/o0ytTUmKHM

Apr 16, 2022 · 2 likes · 117 followers View post →
Dataemia
@Dataemia · X

Reader response: Circulating cortisol and cognitive and structural brain measures: The Framingham Heart Study - https://t.co/6XK9P3TN0b https://t.co/8Bl7jYLMTY

Oct 19, 2019 · 966 followers View post →
BrainSights iOS App
@BrainSightsApp · X

Editors' note: Circulating cortisol and cognitive and structural brain measures: The Framingham Heart Study - AAN Neurology via BrainSights for iOS https://t.co/Ek6B5cJNGp

Oct 7, 2019 · 313 followers View post →

All mentions

Kirana
@kirana_dns · X

RT @SaraBangtan07: Source: https://t.co/SxSGzDA5p4

Sep 14, 2025 · 1 share · 224 followers View post →
Sara (Rest)
@SaraBangtan07 · X

Source: https://t.co/SxSGzDA5p4

Sep 14, 2025 · 19 likes · 1 share · 21,823 followers View post →
Gurvangal Hospital
@GurvangalH · X

#Стрессийн гормон болох кортизол нь их хэмжээгээр ялгарах нь ой тогтоолтыг бууруулах мөн тархины хэмжээг багасгадаг болохыг судалгаагаар тогтоожээ. Эх сурвалж: Circulating cortisol and cognitive and structural brain measures: The Framingham Heart Study. Neurology. 2018 Nov 20 https://t.co/ZfyTeKeiAf

Aug 18, 2022 View post →
@AdaraAstin@smutlandia.com is not here: see Pin
@AdaraAstin · X

@rche_types Me, too. The mechanism (at least partly) is high cortisol levels from the relentless high stress impair cognitive function. https://t.co/6b5IjrCp0x

May 22, 2022 · 2 likes · 1 share · 508 followers View post →
Mahmoud Abdelwahed
@MahmoudAwahed1 · X

@HossamBegovic @amr_sugar البحث كامل خدلك فكرة https://t.co/o0ytTUmKHM

Apr 16, 2022 · 2 likes · 117 followers View post →
D.
@dee_zeeee · X

RT @_CynthiaThurlow: Chronic stress impacts our brains in negative ways..and can impact cognitive function significantly https://t.co/smw…

Jun 9, 2021 · 1 share · 82 followers View post →
Cynthia Thurlow, NP
@_CynthiaThurlow · X

Chronic stress impacts our brains in negative ways..and can impact cognitive function significantly https://t.co/smwWy4IYBC

Jun 7, 2021 · 8 likes · 1 share · 56,094 followers View post →
Dataemia
@Dataemia · X

Reader response: Circulating cortisol and cognitive and structural brain measures: The Framingham Heart Study - https://t.co/6XK9P3TN0b https://t.co/8Bl7jYLMTY

Oct 19, 2019 · 966 followers View post →
BrainSights iOS App
@BrainSightsApp · X

Editors' note: Circulating cortisol and cognitive and structural brain measures: The Framingham Heart Study - AAN Neurology via BrainSights for iOS https://t.co/Ek6B5cJNGp

Oct 7, 2019 · 313 followers View post →
BrainSights iOS App
@BrainSightsApp · X

Reader response: Circulating cortisol and cognitive and structural brain measures: The Framingham Heart Study - AAN Neurology via BrainSights for iOS https://t.co/ctSD9JvLX5

Oct 7, 2019 · 313 followers View post →
BrainSights iOS App
@BrainSightsApp · X

Author response: Circulating cortisol and cognitive and structural brain measures: The Framingham Heart Study - AAN Neurology via BrainSights for iOS https://t.co/zlQP95t6uy

Oct 7, 2019 · 313 followers View post →
BrainSights iOS App
@BrainSightsApp · X

Reader response: Circulating cortisol and cognitive and structural brain measures: The Framingham Heart Study - AAN Neurology via BrainSights for iOS https://t.co/jNuVkFQF0X

Oct 7, 2019 · 313 followers View post →