October 2018 PMID 30360490

Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation.

Vinicius Cruzat, Marcelo Macedo Rogero, Kevin Noel Keane, Rui Curi, Philip Newsholme

Mentions

69
Peak: 9 in Sep 2020
across 5 sources since Jan 2019

Extended reach

314,065
potential audience

Total likes

448

Video views

18,957

Mentions per month

Jan 2019 – Apr 2025

Where it's discussed

  • X / Twitter41 posts
  • News18 articles
  • Facebook5 posts
  • YouTube4 videos
  • Bluesky1 posts

AI synopsis

What people are saying

The discussions reflect a mix of enthusiasm and critical analysis, with users noting glutamine's vital role in immune cell activity and metabolic functions, as seen in mentions of its use for lymphocytes and macrophages. Words like 'crucial', 'essential', and phrases such as 'deep dive' and 'knowledge is power' underscore a keen interest and recognition of its potential, though some comments are more skeptical, pointing out the limited evidence for real-world immune benefits when supplemented. This tone and choice of words indicate that users see the topic as relevant but also complex and still under investigation.

AgreementModerate agreement

Most discussions acknowledge the importance of glutamine in immune functions and clinical nutrition, with some posts emphasizing its role during stress or catabolic conditions.

InterestHigh interest

Posts use phrases like 'deep dive', 'full article', and mention specific studies, indicating strong curiosity and relevance to the topic.

EngagementModerate engagement

Comments refer to mechanisms, such as glutamine's use in synthesis and immune cell activity, showing active engagement and interest in the details.

ImpactNeutral impact

While many recognize its significance, some posts highlight the lack of conclusive evidence in vivo, suggesting a cautious view about its definitive impact.

Abstract in brief

  • Glutamine is the most abundant amino acid in the body and is crucial for immune cell functions such as lymphocyte growth, macrophage activity, and neutrophil bacteria-killing.
  • During severe illness or stress, glutamine becomes essential for maintaining metabolic balance, but its levels may be disrupted, leading to the use of glutamine supplements in clinical nutrition, especially for immune-compromised individuals.
  • Despite known benefits of glutamine supplementation for immune health, more research is needed to determine the best ways to use it in different catabolic conditions, and how it truly impacts patient outcomes in real-life scenarios.]

Top posts

Most liked on X and Bluesky
Nutrients MDPI
@Nutrients_MDPI · X

Editor's Choice #mdpinutrients : Review by Vinicius Cruzat et and Philip Newsholme @philnewsholme et al. #Glutamine: #Metabolism and Immune Function, Supplementation and Clinical Translation See detail at: https://t.co/US5VeIqvSD https://t.co/YgXMCRof00

Sep 24, 2020 · 18 likes · 9 shares · 11,217 followers View post →
Andy Galpin, PhD
@DrAndyGalpin · X

Glutamine is the most abundant AA in body & used same or > than glucose in many immune cells (lymphocytes, cytokines, macrophages, neutrophil bacterial killing, etc.). However, almost no evidence it yields true in vivo immune outcomes when supplemented. https://t.co/eEfRuQhiWy

Feb 17, 2021 · 13 likes · 1 share · 94,825 followers View post →
Rene Sugar
@renesugar · X

Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation https://t.co/LTHcYC358L

Oct 26, 2023 · 12 likes · 1 share · 3,952 followers View post →
分子栄養学の恵先生
@kayamamegumi · X

#グルタミンは リンパ球の増殖 サイトカイン産生 #マクロファージ活性 #好中球 の細菌殺傷 に必要な栄養素 主要臓器における #グルタミン代謝 が 免疫系の細胞にとって どのように重要であるか 説明してある↓論文 https://t.co/oOv0xJk8wX

Oct 23, 2019 · 10 likes · 12,461 followers View post →
Strength For Life
@Strength4_Life · X

Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation https://t.co/iErHvpgHZY https://t.co/jJh8EPsJzL

Mar 17, 2020 · 8 likes · 2 shares · 11,563 followers View post →
Sparrow / Liz
@untonuggan.bsky.social · Bluesky

Cells that preferentially use glutamine for fuel include: Enterocytes (cells lining the small intestine) www.ncbi.nlm.nih.gov/pmc/articles... Many immune cells pubmed.ncbi.nlm.nih.gov/30360490/ Glutamine can also be used to synthesize glutathione, an antioxidant important for liver health

Jul 10, 2024 · 5 likes · 1 share View post →

All mentions

TheVitaDoc
@VitaDoc1 · X

Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation https://t.co/yX66K2lRcP

Apr 1, 2025 · 18,423 followers View post →
TheVitaDoc
@VitaDoc1 · X

Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation https://t.co/yX66K2mp2n

Mar 4, 2025 · 18,423 followers View post →
Bader alshatti Ms
@alshatti_fit · X

1- الجهاز المناعي يحميك الجهاز المناعي من العدوى كما أنه يضمن أن خلاياك المناعية لا تهاجم خلايا جسمك فالذين يعانون من أمراض معينه لديهم مستويات منخفضة من الجلوتامين فيمكن أن يساعد المكمل في تحسين وظيفة الجهاز المناعي وتسريع عملية الشفاء https://t.co/bSZpmjiuoR

Nov 21, 2024 · 1 like · 9,911 followers View post →
Sparrow / Liz
@untonuggan.bsky.social · Bluesky

Cells that preferentially use glutamine for fuel include: Enterocytes (cells lining the small intestine) www.ncbi.nlm.nih.gov/pmc/articles... Many immune cells pubmed.ncbi.nlm.nih.gov/30360490/ Glutamine can also be used to synthesize glutathione, an antioxidant important for liver health

Jul 10, 2024 · 5 likes · 1 share View post →
Paulo Lemos l Nutricionista
@paulonutri_ · X

May 7, 2024 · 322 followers View post →
Anurag Sharma
@AnuragSharmaFJ · X

Check out the full article for a deep dive into the world of glutamine and its impact on immunity. Knowledge is power!

Mar 15, 2024 · 15 followers View post →
Pablo Maure Inmunoterapia
@PInmunoterapia · X

RT @renesugar: Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation https://t.co/LTHcYC358L

Oct 28, 2023 · 1 share · 1,510 followers View post →
GLASS_PhD
@joybeingfree99 · X

RT @renesugar: https://t.co/LTHcYC3CYj "For this reason, glutamine is currently part of clinical nutrition supplementation protocols and/o…

Oct 27, 2023 · 2 shares · 6,644 followers View post →
GLASS_PhD
@joybeingfree99 · X

RT @renesugar: https://t.co/LTHcYC3CYj "During catabolic/hypercatabolic situations glutamine can become essential for metabolic function,…

Oct 27, 2023 · 1 share · 6,644 followers View post →
GLASS_PhD
@joybeingfree99 · X

RT @renesugar: https://t.co/LTHcYC3CYj "For instance, in vitro and in vivo studies have determined that glutamine is an essential nutrient…

Oct 27, 2023 · 1 share · 6,644 followers View post →
Dr. Thomas Ichim
@exosome · X

RT @renesugar: https://t.co/LTHcYC3CYj "For this reason, glutamine is currently part of clinical nutrition supplementation protocols and/o…

Oct 27, 2023 · 2 shares · 33,167 followers View post →
Rene Sugar
@renesugar · X

https://t.co/LTHcYC3CYj "For this reason, glutamine is currently part of clinical nutrition supplementation protocols and/or recommended for immune suppressed individuals."

Oct 26, 2023 · 4 likes · 2 shares · 3,952 followers View post →
Rene Sugar
@renesugar · X

https://t.co/LTHcYC3CYj "During catabolic/hypercatabolic situations glutamine can become essential for metabolic function, but its availability may be compromised due to the impairment of homeostasis in the inter-tissue metabolism of amino acids."

Oct 26, 2023 · 2 likes · 1 share · 3,952 followers View post →
Rene Sugar
@renesugar · X

https://t.co/LTHcYC3CYj "For instance, in vitro and in vivo studies have determined that glutamine is an essential nutrient for lymphocyte proliferation and cytokine production, macrophage phagocytic plus secretory activities, and neutrophil bacterial killing."

Oct 26, 2023 · 1 like · 1 share · 3,952 followers View post →
Rene Sugar
@renesugar · X

Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation https://t.co/LTHcYC358L

Oct 26, 2023 · 12 likes · 1 share · 3,952 followers View post →
Jasmin Plan
@JasminPlan · X

Constantly fighting an infection destroys tissue over time: Is glutathione still the correct “Mother Hormone” to use? Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation - PMC https://t.co/9JJQoz70LI

Jul 20, 2023 · 1 like · 285 followers View post →
LeAnne LawtonTancred
@LeAnneTancred · X

Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation https://t.co/naGG3UazMk

Feb 19, 2023 · 987 followers View post →
つとむ
@tsutomuinfinity · X

Nutrients | Free Full-Text | Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation https://t.co/wYoR5eZoMd

Jan 20, 2023 · 188 followers View post →
つとむ
@tsutomuinfinity · X

RT @keisuke4713: glutamin酸(G):代謝と免疫 https://t.co/dqB9ShZL7R 青⇦はG合成 白⇦はG消費 健康・摂食でG貯蔵は

Jan 20, 2023 · 2 shares · 188 followers View post →
tune
@keisuke4713 · X

glutamin酸(G):代謝と免疫 https://t.co/dqB9ShZL7R 青⇦はG合成 白⇦はG消費 健康・摂食でG貯蔵は

Jan 20, 2023 · 1 like · 2 shares · 3,737 followers View post →
Neuron Idiot
@neuronidiot · X

https://t.co/ioDdwPKUDt

Oct 15, 2021 · 4 followers View post →
OJSN
@iamojsn · X

RT @DrAndyGalpin: Glutamine is the most abundant AA in body & used same or > than glucose in many immune cells (lymphocytes, cytokines, mac…

Feb 17, 2021 · 1 share · 14,996 followers View post →
Maurício Lima
@dj_surfista · X

A #glutamina é o AA mais abundante no corpo e usado igual ou > que a glicose em células do sistema imunológico (linfócitos, citocinas, macrófagos, etc.). No entanto, quase nenhuma evidência de que produz resultados imunes in vivo reais quando suplementada. https://t.co/UL4SdZij3f

Feb 17, 2021 · 3 likes · 742 followers View post →
Andy Galpin, PhD
@DrAndyGalpin · X

Glutamine is the most abundant AA in body & used same or > than glucose in many immune cells (lymphocytes, cytokines, macrophages, neutrophil bacterial killing, etc.). However, almost no evidence it yields true in vivo immune outcomes when supplemented. https://t.co/eEfRuQhiWy

Feb 17, 2021 · 13 likes · 1 share · 94,825 followers View post →
entropyisorder
@entropyisorder · X

37/365 Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation

Jan 12, 2021 · 467 followers View post →
圧到的に成長したぬーとりあはかぴばらと区別できないですわ(極悪令嬢・圧ヌ一ちゃん)
@piyota0 · X

RT @Nutrients_MDPI: Editor's Choice #mdpinutrients : Review by Vinicius Cruzat et and Philip Newsholme @philnewsholme et al. #Glutamine:…

Oct 21, 2020 · 9 shares · 2,777 followers View post →
Hormone Connection
@HormoneCnxn · X

RT @Nutrients_MDPI: Editor's Choice #mdpinutrients : Review by Vinicius Cruzat et and Philip Newsholme @philnewsholme et al. #Glutamine:…

Sep 25, 2020 · 9 shares · 122 followers View post →
Antioxidants in Health & Disease
@AntioxidantCnxn · X

RT @Nutrients_MDPI: Editor's Choice #mdpinutrients : Review by Vinicius Cruzat et and Philip Newsholme @philnewsholme et al. #Glutamine:…

Sep 25, 2020 · 9 shares · 266 followers View post →
JoaquimLamora
@JoaquimLamora · X

RT @Nutrients_MDPI: Editor's Choice #mdpinutrients : Review by Vinicius Cruzat et and Philip Newsholme @philnewsholme et al. #Glutamine:…

Sep 24, 2020 · 9 shares · 1,137 followers View post →
Nutr. Victor Jauregui
@VictorNutr95 · X

RT @Nutrients_MDPI: Editor's Choice #mdpinutrients : Review by Vinicius Cruzat et and Philip Newsholme @philnewsholme et al. #Glutamine:…

Sep 24, 2020 · 9 shares · 49 followers View post →
Nutrición Colombia
@NutrirAColombia · X

Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation ##mdpinutrients a través de @Nutrients_MDPI

Sep 24, 2020 · 103 followers View post →
Noemi Cuenca (Dietista-Nutricionista)
@noemicuencaq · X

RT @Nutrients_MDPI: Editor's Choice #mdpinutrients : Review by Vinicius Cruzat et and Philip Newsholme @philnewsholme et al. #Glutamine:…

Sep 24, 2020 · 9 shares · 539 followers View post →
備忘録
@bibourokuabc · X

RT @Nutrients_MDPI: Editor's Choice #mdpinutrients : Review by Vinicius Cruzat et and Philip Newsholme @philnewsholme et al. #Glutamine:…

Sep 24, 2020 · 9 shares · 228 followers View post →
Pau Oller
@PauOller · X

RT @Nutrients_MDPI: Editor's Choice #mdpinutrients : Review by Vinicius Cruzat et and Philip Newsholme @philnewsholme et al. #Glutamine:…

Sep 24, 2020 · 9 shares · 7,417 followers View post →
Nutrients MDPI
@Nutrients_MDPI · X

Editor's Choice #mdpinutrients : Review by Vinicius Cruzat et and Philip Newsholme @philnewsholme et al. #Glutamine: #Metabolism and Immune Function, Supplementation and Clinical Translation See detail at: https://t.co/US5VeIqvSD https://t.co/YgXMCRof00

Sep 24, 2020 · 18 likes · 9 shares · 11,217 followers View post →
Ирина Баринова
@DAZy81 · X

RT @Strength4_Life: Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation https://t.co/iErHvpgHZY https://t.…

Mar 17, 2020 · 2 shares · 34 followers View post →
Strength For Life
@Strength4_Life · X

Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation https://t.co/iErHvpgHZY https://t.co/jJh8EPsJzL

Mar 17, 2020 · 8 likes · 2 shares · 11,563 followers View post →
Alex
@AlexViKu · X

Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation https://t.co/oGS5t7wMZH https://t.co/rNuzoPyasy

Dec 20, 2019 · 96 followers View post →
分子栄養学の恵先生
@kayamamegumi · X

#グルタミンは リンパ球の増殖 サイトカイン産生 #マクロファージ活性 #好中球 の細菌殺傷 に必要な栄養素 主要臓器における #グルタミン代謝 が 免疫系の細胞にとって どのように重要であるか 説明してある↓論文 https://t.co/oOv0xJk8wX

Oct 23, 2019 · 10 likes · 12,461 followers View post →
Julia Woodman #Truth #Freedom #Consciousness #MEHA
@WoodmanJulia · X

Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation. - PubMed - NCBI https://t.co/lz7btBm5SP

Jun 25, 2019 · 7,286 followers View post →
Pilar Tejada
@ptejadag · X

RT @GrupoNutri: Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation 2018 https://t.co/3rGDo7VnN1 Revisión i…

Jan 10, 2019 · 2 shares · 182 followers View post →
Grupo Nutrición SEFH
@GrupoNutri · X

Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation 2018 https://t.co/3rGDo7VnN1 Revisión integrada y su aplicación practica

Jan 10, 2019 · 3 likes · 2 shares · 5,486 followers View post →