Orthop J Sports Med October 2018 PMID 30386805

Efficacy of Vitamin C Supplementation on Collagen Synthesis and Oxidative Stress After Musculoskeletal Injuries: A Systematic Review.

Nicholas N DePhillipo, Zachary S Aman, Mitchell I Kennedy, J P Begley, Gilbert Moatshe, Robert F LaPrade

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Mentions

109
Peak: 14 in Feb 2024
across 5 sources since Jan 2019

Extended reach

501,993
potential audience

Total likes

1,734

Video views

36,140

Mentions per month

Jan 2019 – May 2025

Where it's discussed

  • News69 articles
  • X / Twitter34 posts
  • YouTube2 videos
  • Facebook2 posts
  • Blogs2 articles

AI synopsis

What people are saying

Discussions reflect a balanced curiosity about vitamin C's role in tissue healing, with users highlighting phrases like 'increase collagen synthesis' and 'scientific evidence,' which indicate genuine interest and an intent to deepen understanding. The tone varies from tentative optimism to proactive information sharing, emphasizing the relevance of the research while acknowledging that the findings are still preliminary and require further validation.

AgreementModerate agreement

Most discussed posts acknowledge the potential benefits of vitamin C for collagen synthesis and healing, though some express cautious optimism rather than full endorsement, reflecting a generally positive but nuanced reception.

InterestHigh interest

The discussions show high curiosity, with many posts emphasizing the relevance of vitamin C and collagen in injury recovery and mentioning specific nutrients like vitamin D and curcumin, indicating active engagement with the topic.

EngagementModerate engagement

Posts include references to scientific research, expressing intent to seek more information via links or suggestions to search for additional studies, demonstrating a moderate level of deep engagement.

ImpactModerate impact

Participants seem to perceive the publication as moderately impactful, with some commentary on its scientific basis and potential effects, but likely awaiting more conclusive evidence before widespread adoption.

Abstract in brief

  • Recent studies suggest that vitamin C may improve collagen synthesis and healing in musculoskeletal injuries.
  • The purpose of the review was to evaluate vitamin C's role in treatment protocols, its effectiveness in healing bone, tendon, and ligament injuries, and its antioxidant properties that aid collagen production.
  • After extensive research filtering 286 articles, 10 studies were analyzed: while some preclinical findings showed benefits of vitamin C on bone and tendon healing, clinical evidence was mixed with no significant long-term effects observed in fracture healing.

Top posts

Most liked on X and Bluesky
Agingdoc
@agingdoc1 · X

Efficacy of Vitamin C Supplementation on Collagen Synthesis and Oxidative Stress After Musculoskeletal Injuries: A Systematic Review https://t.co/Pqi2qFcRLH https://t.co/IFg6grmBTm

Feb 4, 2024 · 29 likes · 13 shares · 42,510 followers View post →
Saúl Sánchez
@SaulNutri · X

@JoseAntNaval @aherra27 Te adjunto algunos por aquí. Saludos! https://t.co/OQnT6Bbd00 https://t.co/9uHxy4vqzP https://t.co/n41pSJvUD6 https://t.co/HsV6UbFG3z

May 17, 2020 · 11 likes · 1 share · 108,061 followers View post →
Saúl Sánchez
@SaulNutri · X

Eso sí, incluir un aporte extra de vitamina C de 1 gramo al día incrementará la síntesis de colágeno, necesario para dotar al músculo de buena función contráctil.

Oct 3, 2021 · 7 likes · 1 share · 108,061 followers View post →
IberianCitizen
@IberianCitizen · X

@Samuel36916439 Partiendo d la pérdida d peso, ejercicio y una alimentación sin ultraprocesados con aporte pescado y verduras como base, colágeno, vitamina D, C, curcumina y jengibre. #osteoartritis https://t.co/FVlYSYNkTq https://t.co/Ec7B0dzM1J https://t.co/kJOFSabIUe https://t.co/Ek76vkDGQt https://t.co/aXxUQtgDAS

Nov 19, 2022 · 7 likes · 2 shares · 12,900 followers View post →
Saúl Sánchez
@SaulNutri · X

@FranAmarcano Te dejo un par de ellos por aquí. En encuentras bastantes más con una búsqueda rápida en pubmed

Apr 18, 2021 · 6 likes · 108,061 followers View post →
Mikki Williden PhD
@MikkiWilliden · X

Efficacy of Vitamin C Supplementation on Collagen Synthesis and Oxidative Stress After Musculoskeletal Injuries: A Systematic Review https://t.co/TYuhb3bnfb

Nov 28, 2019 · 5 likes · 3 shares · 2,238 followers View post →

All mentions

Tabatha
@araran100 · X

RT @keisuke4713: 関節の健康 Collagen補給https://t.co/xYm8Bh9ekz ギリシャ語κόλλα(kólla:接着剤) -γενής(genḗs:生成)由来 ビタミンC、銅、亜鉛;Collagen生合成⬆️ https://t.co/2e…

May 15, 2025 · 2 shares · 17,476 followers View post →
Super Plant Based Health
@y_rifo60592 · X

Todo lo que necesitas saber sobre el colágeno y si se debe o no suplementarlo en tu dieta... el video más completo que encontré hasta ahora! (Además de que Mic es un ídolo total!) https://t.co/V3GAdoIQdG

Aug 21, 2024 · 9 followers View post →
Tabatha
@araran100 · X

RT @keisuke4713: 関節の健康 Collagen補給https://t.co/xYm8Bh9ekz ギリシャ語κόλλα(kólla:接着剤) -γενής(genḗs:生成)由来 ビタミンC、銅、亜鉛;Collagen生合成⬆️ https://t.co/2e…

Jun 9, 2024 · 2 shares · 17,476 followers View post →
tune
@keisuke4713 · X

関節の健康 Collagen補給https://t.co/xYm8Bh9ekz ギリシャ語κόλλα(kólla:接着剤) -γενής(genḗs:生成)由来 ビタミンC、銅、亜鉛;Collagen生合成⬆️ https://t.co/2eyKBlZdjr https://t.co/XIpxf6Jrg7 https://t.co/oNA9V0YT5R 動物副産物から得られる主なCollagen製品 https://t.co/ynTfMQDXZu

Jun 8, 2024 · 2 likes · 2 shares · 3,744 followers View post →
Dominique Lehman
@Dominique612 · X

https://t.co/LyDK9cAFEq

May 26, 2024 · 617 followers View post →
J Sam
@JaicSam · X

RT @agingdoc1: Efficacy of Vitamin C Supplementation on Collagen Synthesis and Oxidative Stress After Musculoskeletal Injuries: A Systemati…

Feb 6, 2024 · 13 shares · 979 followers View post →
Patricia G. Freire
@gallardomp · X

RT @agingdoc1: Efficacy of Vitamin C Supplementation on Collagen Synthesis and Oxidative Stress After Musculoskeletal Injuries: A Systemati…

Feb 5, 2024 · 13 shares · 874 followers View post →
Slawomir
@Slawomi18369321 · X

RT @agingdoc1: Efficacy of Vitamin C Supplementation on Collagen Synthesis and Oxidative Stress After Musculoskeletal Injuries: A Systemati…

Feb 5, 2024 · 13 shares · 85 followers View post →
Luis
@lulopson · X

RT @agingdoc1: Efficacy of Vitamin C Supplementation on Collagen Synthesis and Oxidative Stress After Musculoskeletal Injuries: A Systemati…

Feb 5, 2024 · 13 shares · 447 followers View post →
Samantha
@GenXsamantha · X

RT @agingdoc1: Efficacy of Vitamin C Supplementation on Collagen Synthesis and Oxidative Stress After Musculoskeletal Injuries: A Systemati…

Feb 5, 2024 · 13 shares · 3,530 followers View post →
Oscar Andres
@OscarAndresMD · X

RT @agingdoc1: Efficacy of Vitamin C Supplementation on Collagen Synthesis and Oxidative Stress After Musculoskeletal Injuries: A Systemati…

Feb 5, 2024 · 13 shares · 549 followers View post →
Zack
@keychupkicap · X

RT @agingdoc1: Efficacy of Vitamin C Supplementation on Collagen Synthesis and Oxidative Stress After Musculoskeletal Injuries: A Systemati…

Feb 4, 2024 · 13 shares · 390 followers View post →
DrRPalmquist
@DrPalmquist · X

RT @agingdoc1: Efficacy of Vitamin C Supplementation on Collagen Synthesis and Oxidative Stress After Musculoskeletal Injuries: A Systemati…

Feb 4, 2024 · 13 shares · 3,171 followers View post →
Akane
@Akanegg3 · X

RT @agingdoc1: Efficacy of Vitamin C Supplementation on Collagen Synthesis and Oxidative Stress After Musculoskeletal Injuries: A Systemati…

Feb 4, 2024 · 13 shares · 234 followers View post →
Mind Your Science!
@MindYourSci · X

RT @agingdoc1: Efficacy of Vitamin C Supplementation on Collagen Synthesis and Oxidative Stress After Musculoskeletal Injuries: A Systemati…

Feb 4, 2024 · 13 shares · 132 followers View post →
Juhana Harju
@JuhanaHarju · X

RT @agingdoc1: Efficacy of Vitamin C Supplementation on Collagen Synthesis and Oxidative Stress After Musculoskeletal Injuries: A Systemati…

Feb 4, 2024 · 13 shares · 1,691 followers View post →
John Greene
@Greene_Thoughts · X

RT @agingdoc1: Efficacy of Vitamin C Supplementation on Collagen Synthesis and Oxidative Stress After Musculoskeletal Injuries: A Systemati…

Feb 4, 2024 · 13 shares · 1,723 followers View post →
Agingdoc
@agingdoc1 · X

Efficacy of Vitamin C Supplementation on Collagen Synthesis and Oxidative Stress After Musculoskeletal Injuries: A Systematic Review https://t.co/Pqi2qFcRLH https://t.co/IFg6grmBTm

Feb 4, 2024 · 29 likes · 13 shares · 42,510 followers View post →
Tom Coughlin
@tecoughlin · X

Reference: https://t.co/9NYSP365RO

Feb 1, 2024 · 2 likes · 4,282 followers View post →
Dr. Litol
@drlitolsalud · X

RT @IberianCitizen: @Samuel36916439 Partiendo d la pérdida d peso, ejercicio y una alimentación sin ultraprocesados con aporte pescado y ve…

Dec 17, 2022 · 2 shares · 27 followers View post →
IberianCitizen
@IberianCitizen · X

RT @IberianCitizen: @Samuel36916439 Partiendo d la pérdida d peso, ejercicio y una alimentación sin ultraprocesados con aporte pescado y ve…

Nov 19, 2022 · 2 shares · 12,900 followers View post →
IberianCitizen
@IberianCitizen · X

@Samuel36916439 Partiendo d la pérdida d peso, ejercicio y una alimentación sin ultraprocesados con aporte pescado y verduras como base, colágeno, vitamina D, C, curcumina y jengibre. #osteoartritis https://t.co/FVlYSYNkTq https://t.co/Ec7B0dzM1J https://t.co/kJOFSabIUe https://t.co/Ek76vkDGQt https://t.co/aXxUQtgDAS

Nov 19, 2022 · 7 likes · 2 shares · 12,900 followers View post →
CEO NUBE_ byjulie
@nutriendoamx · X

RT @SaulNutri: Eso sí, incluir un aporte extra de vitamina C de 1 gramo al día incrementará la síntesis de colágeno, necesario para dotar a…

Oct 3, 2021 · 1 share · 257 followers View post →
Saúl Sánchez
@SaulNutri · X

Eso sí, incluir un aporte extra de vitamina C de 1 gramo al día incrementará la síntesis de colágeno, necesario para dotar al músculo de buena función contráctil.

Oct 3, 2021 · 7 likes · 1 share · 108,061 followers View post →
Sage Clinical Med
@SageClinMed · X

Basic science investigations on the biochemical pathways after a #musculoskeletal injury have suggested that #vitaminC may enhance collagen synthesis and soft tissue healing @AOSSM_SportsMed @OJSM_SportsMed https://t.co/MHTWC43bRy

Jun 4, 2021 · 3,267 followers View post →
The Unwinder
@the_unwinder · X

Getting more vitamin C will increase collagen synthesis: https://t.co/ufpuXuEZIv

May 7, 2021 · 318 followers View post →
Saúl Sánchez
@SaulNutri · X

@FranAmarcano Te dejo un par de ellos por aquí. En encuentras bastantes más con una búsqueda rápida en pubmed

Apr 18, 2021 · 6 likes · 108,061 followers View post →
Fernando Meza
@capicave · X

RT @SaulNutri: @JoseAntNaval @aherra27 Te adjunto algunos por aquí. Saludos! https://t.co/OQnT6Bbd00 https://t.co/9uHxy4vqzP https://t.co/…

May 17, 2020 · 1 share · 630 followers View post →
Saúl Sánchez
@SaulNutri · X

@JoseAntNaval @aherra27 Te adjunto algunos por aquí. Saludos! https://t.co/OQnT6Bbd00 https://t.co/9uHxy4vqzP https://t.co/n41pSJvUD6 https://t.co/HsV6UbFG3z

May 17, 2020 · 11 likes · 1 share · 108,061 followers View post →
Eisnel Hdez
@EisnelHR · X

RT @MikkiWilliden: Efficacy of Vitamin C Supplementation on Collagen Synthesis and Oxidative Stress After Musculoskeletal Injuries: A Syste…

Nov 29, 2019 · 3 shares · 26 followers View post →
Tom Englezos
@tomenglezos · X

RT @MikkiWilliden: Efficacy of Vitamin C Supplementation on Collagen Synthesis and Oxidative Stress After Musculoskeletal Injuries: A Syste…

Nov 28, 2019 · 3 shares · 1,284 followers View post →
Mikki Williden PhD
@MikkiWilliden · X

Efficacy of Vitamin C Supplementation on Collagen Synthesis and Oxidative Stress After Musculoskeletal Injuries: A Systematic Review https://t.co/TYuhb3bnfb

Nov 28, 2019 · 5 likes · 3 shares · 2,238 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @andreatognelli: Efficacy of Vitamin C Supplementation on Collagen Synthesis and Oxidative Stress After Musculoskeletal Injuries: A Syst…

Jan 24, 2019 · 1 share · 6,703 followers View post →
Andrea Tognelli
@andreatognelli · X

Efficacy of Vitamin C Supplementation on Collagen Synthesis and Oxidative Stress After Musculoskeletal Injuries: A Systematic Review. - PubMed - NCBI https://t.co/QhGskNg98E

Jan 24, 2019 · 1 share · 810 followers View post →