January 2019 PMID 30427999

Association of Testosterone Treatment With Alleviation of Depressive Symptoms in Men: A Systematic Review and Meta-analysis.

Andreas Walther, Jonas Breidenstein, Robert Miller

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Mentions

73
Peak: 5 in May 2023
across 6 sources since Dec 2018

Extended reach

338,230
potential audience

Total likes

609

Video views

19,197

Mentions per month

Dec 2018 – Sep 2025

Where it's discussed

  • News36 articles
  • X / Twitter19 posts
  • Facebook8 posts
  • Reddit5 posts
  • YouTube3 videos
  • Blogs2 articles

AI synopsis

What people are saying

The discussions demonstrate strong agreement by highlighting that testosterone treatment significantly alleviates depressive symptoms, with examples referencing the meta-analysis of nearly 2,000 men. Participants discuss potential clinical applications, with phrases like 'every man should have their levels checked' and 'treatment is effective,' reflecting high interest, engagement, and perceived impact.

AgreementStrong agreement

All discussions strongly endorse the positive findings of the study, emphasizing the efficacy of testosterone therapy in reducing depressive symptoms.

InterestHigh interest

The discussions show high engagement and curiosity, with users calling for broader screening and treatment considerations.

EngagementHigh engagement

Several posts reference specific aspects of the research, such as the number of trials and the significant results, indicating deep engagement.

ImpactHigh impact

The comments suggest the findings could influence clinical practice and public health policy regarding depression treatment and testosterone testing.

Abstract in brief

  • The systematic review and meta-analysis examined whether testosterone treatment helps reduce depressive symptoms in men, especially considering factors like age, testosterone levels, and treatment details.
  • Out of 7690 records, 27 high-quality randomized controlled trials involving 1890 men were analyzed, showing that testosterone treatment significantly improves depressive symptoms compared to a placebo.
  • The findings suggest that testosterone therapy could be a promising option for alleviating depression in men, but further research is needed to clarify optimal treatment protocols and long-term effects.]

Top posts

Most liked on X and Bluesky
Nicholas Fabiano, MD
@NTFabiano · X

These findings are from a study in @JAMAPsych which examined the association of testosterone treatment with alleviation of depressive symptoms in men. https://t.co/OMg5lfiLVE 2/10 https://t.co/ogVrBTF2xO

Feb 3, 2025 · 58 likes · 3 shares · 108,741 followers View post →
Mike Hart, M.D
@drmikehart · X

Every man with symptoms of depression should have their testosterone levels checked. Testosterone treatment significantly reduced depressive symptoms compared to placebo in a meta-analysis of 27 randomized controlled trials, including 1890 men. https://t.co/e519ccwVnv

May 21, 2023 · 38 likes · 4 shares · 66,401 followers View post →
Dr. Michael Sagner, MD
@DrMichaelSagner · X

Association of Testosterone Treatment With Alleviation of Depressive Symptoms in Men. - The available evidence supports the clinical utility of adjunct testosterone treatment for depressive symptoms in men. https://t.co/8QtXcMawbq https://t.co/0H5urqUqUY

Jan 4, 2019 · 2 likes · 5,356 followers View post →
Juan mosca
@drjmosca · X

Association of Testosterone Treatment With Alleviation of Depressive Symptoms in Men: A Systematic Review and Meta-analysis. | Depressive Disorders | JAMA Psychiatry | JAMA Network https://t.co/Fx6Ric6Lbf

Apr 16, 2019 · 2 likes · 1 share · 489 followers View post →
Mike Hart, M.D
@drmikehart · X

Jun 15, 2025 · 1 like · 66,401 followers View post →
@DrGottfried
@DrGottfried · X

Testosterone treatment is effective in reducing depressive symptoms in men: A Systematic Review and Meta-… https://t.co/CEmfvbMsE1

Sep 3, 2021 · 1 like · 2 shares · 16,715 followers View post →

All mentions

Mike Hart, M.D
@drmikehart · X

Jun 15, 2025 · 1 like · 66,401 followers View post →
GUT-AI Foundation — AI/acc
@GUT_AI_F · X

RT @NTFabiano: These findings are from a study in @JAMAPsych which examined the association of testosterone treatment with alleviation of d…

Feb 3, 2025 · 3 shares · 341 followers View post →
Nicholas Fabiano, MD
@NTFabiano · X

These findings are from a study in @JAMAPsych which examined the association of testosterone treatment with alleviation of depressive symptoms in men. https://t.co/OMg5lfiLVE 2/10 https://t.co/ogVrBTF2xO

Feb 3, 2025 · 58 likes · 3 shares · 108,741 followers View post →
Dr. Michael Sagner, MD
@DrMichaelSagner · X

RT @drmikehart: Every man with symptoms of depression should have their testosterone levels checked. Testosterone treatment significantly…

May 22, 2023 · 4 shares · 5,356 followers View post →
Peter Wong
@Original182 · X

RT @drmikehart: Every man with symptoms of depression should have their testosterone levels checked. Testosterone treatment significantly…

May 21, 2023 · 4 shares · 262 followers View post →
Jill Woodworth
@jwoodworthtalks · X

RT @drmikehart: Every man with symptoms of depression should have their testosterone levels checked. Testosterone treatment significantly…

May 21, 2023 · 4 shares · 5,274 followers View post →
Jared J Wallen MD MBA
@JJWUrology · X

RT @drmikehart: Every man with symptoms of depression should have their testosterone levels checked. Testosterone treatment significantly…

May 21, 2023 · 4 shares · 3,635 followers View post →
Mike Hart, M.D
@drmikehart · X

Every man with symptoms of depression should have their testosterone levels checked. Testosterone treatment significantly reduced depressive symptoms compared to placebo in a meta-analysis of 27 randomized controlled trials, including 1890 men. https://t.co/e519ccwVnv

May 21, 2023 · 38 likes · 4 shares · 66,401 followers View post →
Teresa Hartman
@thartman2u · X

RT @DrGottfried: Testosterone treatment is effective in reducing depressive symptoms in men: A Systematic Review and Meta-… https://t.co/CE…

Sep 4, 2021 · 2 shares · 3,479 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @DrGottfried: Testosterone treatment is effective in reducing depressive symptoms in men: A Systematic Review and Meta-… https://t.co/CE…

Sep 3, 2021 · 2 shares · 6,717 followers View post →
@DrGottfried
@DrGottfried · X

Testosterone treatment is effective in reducing depressive symptoms in men: A Systematic Review and Meta-… https://t.co/CEmfvbMsE1

Sep 3, 2021 · 1 like · 2 shares · 16,715 followers View post →
Shania Quug Quug
@QuugShania · X

RT @Dra_TeraizaMesa: Association of #Testosterone Treatment With Alleviation of #Depressive Symptoms in Men https://t.co/ErK2XcMwPE

Jul 3, 2020 · 1 share · 38 followers View post →
Dra. Teraiza Mesa R Cuenta Oficial ®
@Dra_TeraizaMesa · X

Association of #Testosterone Treatment With Alleviation of #Depressive Symptoms in Men https://t.co/ErK2XcMwPE

Jul 3, 2020 · 1 like · 1 share · 9,090 followers View post →
Interaktionsambulanz
@IA_AMB · X

RT @leoschilbach: Association of Testosterone Treatment With Alleviation of Depressive Symptoms in Men: A Systematic Review and Meta-analys…

Jul 31, 2019 · 2 shares · 484 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @leoschilbach: Association of Testosterone Treatment With Alleviation of Depressive Symptoms in Men: A Systematic Review and Meta-analys…

Jul 30, 2019 · 2 shares · 6,717 followers View post →
Leonhard Schilbach
@leoschilbach · X

Association of Testosterone Treatment With Alleviation of Depressive Symptoms in Men: A Systematic Review and Meta-analysis https://t.co/guJyfthR9K

Jul 30, 2019 · 2 shares · 6,737 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @drjmosca: Association of Testosterone Treatment With Alleviation of Depressive Symptoms in Men: A Systematic Review and Meta-analysis.…

Apr 16, 2019 · 1 share · 6,717 followers View post →
Juan mosca
@drjmosca · X

Association of Testosterone Treatment With Alleviation of Depressive Symptoms in Men: A Systematic Review and Meta-analysis. | Depressive Disorders | JAMA Psychiatry | JAMA Network https://t.co/Fx6Ric6Lbf

Apr 16, 2019 · 2 likes · 1 share · 489 followers View post →
Dr. Michael Sagner, MD
@DrMichaelSagner · X

Association of Testosterone Treatment With Alleviation of Depressive Symptoms in Men. - The available evidence supports the clinical utility of adjunct testosterone treatment for depressive symptoms in men. https://t.co/8QtXcMawbq https://t.co/0H5urqUqUY

Jan 4, 2019 · 2 likes · 5,356 followers View post →