Autophagy and aging: Maintaining the proteome through exercise and caloric restriction Don't need to restrict calories, intermittent fasting will do the job. Exercise powerfully promotes autophagy. Inhibition of autophagy -> premature aging Get on it https://t.co/mTfFrk3Fxx
Autophagy and aging: Maintaining the proteome through exercise and caloric restriction.
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Feb 2019 – Jan 2024Where it's discussed
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X / Twitter75 posts
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Facebook4 posts
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News3 articles
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AI synopsis
What people are saying
The overall tone highlights strong support for the idea that exercise and caloric restriction enhance autophagy, with posts discussing cellular pathways and practical benefits, showing high interest and engagement, such as mention of maintaining cellular health and longevity.
Most discussions support the ideas that exercise and caloric restriction promote autophagy and healthy aging, reflecting strong consensus.
Posts consistently show high interest, referencing scientific pathways, health benefits, and practical implications, indicating engagement with the subject.
Many comments delve into mechanisms, draw parallels with city systems, and challenge or expand on the topic, demonstrating deep engagement.
The discussions emphasize the significance of autophagy for longevity and health, suggesting the topic has a substantial influence on ideas about aging and wellness.
Abstract in brief
- Autophagy helps maintain healthy cells by recycling damaged proteins and organelles, but its activity declines with age, leading to cellular dysfunction and aging-related diseases.
- Both exercise and caloric restriction (CR) promote healthy aging by inhibiting TORC1, a key regulator that suppresses autophagy, thereby enhancing the cell’s ability to clear damaged components.
- The longevity benefits of exercise and CR are likely due to their combined effects on balancing protein production and degradation, maintaining cellular health, and preserving the proteome as signaling pathways overlap.]
Top posts
Most liked on X and BlueskyAutofagia y envejecimiento: mantenimiento del proteoma mediante ejercicio y restricción calórica https://t.co/BGU9cH6ZsE https://t.co/vaNqJ9ce2W
https://t.co/mTfFrk3Fxx
Una ciudad funciona mejor cuando el sistema de recogida de basuras trabaja correctamente. El ejercicio, para el cuerpo, sería como poner más camiones de basura e incineradoras. By
From: "Exercise and CR result in a concomitant downregulation of TORC1 activity and upregulation of autophagy in a number of tissues..." Though a bit date, a good discussion of common pathways https://t.co/y7ZgI9MEJZ https://t.co/hnIKItkxI6 https://t.co/bq3yWx6Bce
5/7 ¿Medicación prediabetes? ¿Qué explica la interacción? Además de efecto suelo en estudios, también importa la dosis ejercicio y metformina combinables. El efecto de ejercicio está en función de intensidad, duración y cronicidad y varía entre individuos https://t.co/Dq95xFwd3O https://t.co/dJ7ebNvjL6
All mentions
Evaluating Bryan Johnson's $2M Longevity Biohacking Strategy for Aging Reversal
Explore Bryan Johnson's biohacking blueprint aimed at reversing aging by promoting autophagy through exercise and caloric restriction, which maintain healthy cells and cellular function to combat age-related decline.
Enhancing Longevity Through Autophagy and Caloric Restriction
Autophagy helps maintain healthy cells by recycling damaged proteins and organelles, but its activity declines with age, leading to cellular dysfunction and aging-related diseases. Exercise and caloric restriction…
@bryan_johnson Autophagy and aging: Maintaining the proteome through exercise and caloric restriction. https://t.co/wH8NY5LSlM
RT @agingdoc1: From: "Exercise and CR result in a concomitant downregulation of TORC1 activity and upregulation of autophagy in a number of…
RT @agingdoc1: From: "Exercise and CR result in a concomitant downregulation of TORC1 activity and upregulation of autophagy in a number of…
RT @agingdoc1: From: "Exercise and CR result in a concomitant downregulation of TORC1 activity and upregulation of autophagy in a number of…
RT @agingdoc1: From: "Exercise and CR result in a concomitant downregulation of TORC1 activity and upregulation of autophagy in a number of…
RT @agingdoc1: From: "Exercise and CR result in a concomitant downregulation of TORC1 activity and upregulation of autophagy in a number of…
RT @agingdoc1: From: "Exercise and CR result in a concomitant downregulation of TORC1 activity and upregulation of autophagy in a number of…
RT @agingdoc1: From: "Exercise and CR result in a concomitant downregulation of TORC1 activity and upregulation of autophagy in a number of…
From: "Exercise and CR result in a concomitant downregulation of TORC1 activity and upregulation of autophagy in a number of tissues..." Though a bit date, a good discussion of common pathways https://t.co/y7ZgI9MEJZ https://t.co/hnIKItkxI6 https://t.co/bq3yWx6Bce
RT @IberianCitizen: Una ciudad funciona mejor cuando el sistema de recogida de basuras trabaja correctamente. El ejercicio, para el cuerpo,…
RT @IberianCitizen: Una ciudad funciona mejor cuando el sistema de recogida de basuras trabaja correctamente. El ejercicio, para el cuerpo,…
RT @IberianCitizen: Una ciudad funciona mejor cuando el sistema de recogida de basuras trabaja correctamente. El ejercicio, para el cuerpo,…
RT @IberianCitizen: Una ciudad funciona mejor cuando el sistema de recogida de basuras trabaja correctamente. El ejercicio, para el cuerpo,…
RT @IberianCitizen: Una ciudad funciona mejor cuando el sistema de recogida de basuras trabaja correctamente. El ejercicio, para el cuerpo,…
RT @IberianCitizen: Una ciudad funciona mejor cuando el sistema de recogida de basuras trabaja correctamente. El ejercicio, para el cuerpo,…
RT @IberianCitizen: Una ciudad funciona mejor cuando el sistema de recogida de basuras trabaja correctamente. El ejercicio, para el cuerpo,…
RT @IberianCitizen: Una ciudad funciona mejor cuando el sistema de recogida de basuras trabaja correctamente. El ejercicio, para el cuerpo,…
RT @IberianCitizen: Una ciudad funciona mejor cuando el sistema de recogida de basuras trabaja correctamente. El ejercicio, para el cuerpo,…
RT @IberianCitizen: Una ciudad funciona mejor cuando el sistema de recogida de basuras trabaja correctamente. El ejercicio, para el cuerpo,…
RT @IberianCitizen: Una ciudad funciona mejor cuando el sistema de recogida de basuras trabaja correctamente. El ejercicio, para el cuerpo,…
RT @IberianCitizen: Una ciudad funciona mejor cuando el sistema de recogida de basuras trabaja correctamente. El ejercicio, para el cuerpo,…
Una ciudad funciona mejor cuando el sistema de recogida de basuras trabaja correctamente. El ejercicio, para el cuerpo, sería como poner más camiones de basura e incineradoras. By
You don’t have to fast to get autophagy. Exercise does it too! https://t.co/dmYV7G9l1L
Autophagy cleans up the cells & during aging it declines. Exercise & calorie restriction (CR) aid in promoting autophagy in the brain & in the tissues. Exercise & CR may balance the making & recycling of cellular proteins to help increase longevity. https://t.co/woRHwENbo9
RT @Mangan150: https://t.co/mTfFrk3Fxx
RT @Mangan150: https://t.co/mTfFrk3Fxx
RT @Mangan150: https://t.co/mTfFrk3Fxx
RT @Mangan150: https://t.co/mTfFrk3Fxx
https://t.co/mTfFrk3Fxx
RT @SaulNutri: Por su parte, tanto el ejercicio como la restricción calórica potencian la homeostasis celular por medio de la eliminación d…
Por su parte, tanto el ejercicio como la restricción calórica potencian la homeostasis celular por medio de la eliminación de orgánulos disfuncionales y sustancias de desecho. Podrían influir positivamente sobre la longitud de los telómeros. https://t.co/BdtB3IXYPh
Autophagy and aging: Maintaining the proteome through exercise and caloric restriction https://t.co/DqAzMEFfwX https://t.co/BJZLmVzQUt
@Broderil No hay debate, la restricción calórica alarga la vida. Sobre lo de las mascarillas...no hay evidencias a favor. Sí varias en contra en distintos contextos. https://t.co/BdtB3IXYPh
RT @IberianCitizen: Autofagia y envejecimiento: mantenimiento del proteoma mediante ejercicio y restricción calórica https://t.co/BGU9cH6Zs…
RT @IberianCitizen: Autofagia y envejecimiento: mantenimiento del proteoma mediante ejercicio y restricción calórica https://t.co/BGU9cH6Zs…
RT @IberianCitizen: Autofagia y envejecimiento: mantenimiento del proteoma mediante ejercicio y restricción calórica https://t.co/BGU9cH6Zs…
RT @IberianCitizen: Autofagia y envejecimiento: mantenimiento del proteoma mediante ejercicio y restricción calórica https://t.co/BGU9cH6Zs…
RT @IberianCitizen: Autofagia y envejecimiento: mantenimiento del proteoma mediante ejercicio y restricción calórica https://t.co/BGU9cH6Zs…
RT @IberianCitizen: Autofagia y envejecimiento: mantenimiento del proteoma mediante ejercicio y restricción calórica https://t.co/BGU9cH6Zs…
RT @IberianCitizen: Autofagia y envejecimiento: mantenimiento del proteoma mediante ejercicio y restricción calórica https://t.co/BGU9cH6Zs…
Autofagia y envejecimiento: mantenimiento del proteoma mediante ejercicio y restricción calórica https://t.co/BGU9cH6ZsE https://t.co/vaNqJ9ce2W
RT @isidoro_cano: 5/7 ¿Medicación prediabetes? ¿Qué explica la interacción? Además de efecto suelo en estudios, también importa la dosis ej…
5/7 ¿Medicación prediabetes? ¿Qué explica la interacción? Además de efecto suelo en estudios, también importa la dosis ejercicio y metformina combinables. El efecto de ejercicio está en función de intensidad, duración y cronicidad y varía entre individuos https://t.co/Dq95xFwd3O https://t.co/dJ7ebNvjL6
RT @agingdoc1: Autophagy and aging: Maintaining the proteome through exercise and caloric restriction https://t.co/C4ruyIdbxo
RT @agingdoc1: Autophagy and aging: Maintaining the proteome through exercise and caloric restriction https://t.co/C4ruyIdbxo
Autophagy and aging: Maintaining the proteome through exercise and caloric restriction https://t.co/C4ruyIdbxo
RT @Mangan150: Autophagy and aging: Maintaining the proteome through exercise and caloric restriction Don't need to restrict calories, int…
RT @Mangan150: Autophagy and aging: Maintaining the proteome through exercise and caloric restriction Don't need to restrict calories, int…
RT @Mangan150: Autophagy and aging: Maintaining the proteome through exercise and caloric restriction Don't need to restrict calories, int…
RT @Mangan150: Autophagy and aging: Maintaining the proteome through exercise and caloric restriction Don't need to restrict calories, int…
RT @Mangan150: Autophagy and aging: Maintaining the proteome through exercise and caloric restriction Don't need to restrict calories, int…
Autophagy and aging: Maintaining the proteome through exercise and caloric restriction - Escobar - 2019 - Aging Cell - Wiley Online Library https://t.co/wK1H1fSw4I
RT @Mangan150: Autophagy and aging: Maintaining the proteome through exercise and caloric restriction Don't need to restrict calories, int…
RT @Mangan150: Autophagy and aging: Maintaining the proteome through exercise and caloric restriction Don't need to restrict calories, int…
RT @Mangan150: Autophagy and aging: Maintaining the proteome through exercise and caloric restriction Don't need to restrict calories, int…
RT @Mangan150: Autophagy and aging: Maintaining the proteome through exercise and caloric restriction Don't need to restrict calories, int…
RT @Mangan150: Autophagy and aging: Maintaining the proteome through exercise and caloric restriction Don't need to restrict calories, int…
RT @Mangan150: Autophagy and aging: Maintaining the proteome through exercise and caloric restriction Don't need to restrict calories, int…
RT @Mangan150: Autophagy and aging: Maintaining the proteome through exercise and caloric restriction Don't need to restrict calories, int…
RT @Mangan150: Autophagy and aging: Maintaining the proteome through exercise and caloric restriction Don't need to restrict calories, int…
RT @Mangan150: Autophagy and aging: Maintaining the proteome through exercise and caloric restriction Don't need to restrict calories, int…
RT @Mangan150: Autophagy and aging: Maintaining the proteome through exercise and caloric restriction Don't need to restrict calories, int…
RT @Mangan150: Autophagy and aging: Maintaining the proteome through exercise and caloric restriction Don't need to restrict calories, int…
RT @Mangan150: Autophagy and aging: Maintaining the proteome through exercise and caloric restriction Don't need to restrict calories, int…
RT @Mangan150: Autophagy and aging: Maintaining the proteome through exercise and caloric restriction Don't need to restrict calories, int…
RT @Mangan150: Autophagy and aging: Maintaining the proteome through exercise and caloric restriction Don't need to restrict calories, int…
RT @Mangan150: Autophagy and aging: Maintaining the proteome through exercise and caloric restriction Don't need to restrict calories, int…
RT @Mangan150: Autophagy and aging: Maintaining the proteome through exercise and caloric restriction Don't need to restrict calories, int…
RT @Mangan150: Autophagy and aging: Maintaining the proteome through exercise and caloric restriction Don't need to restrict calories, int…
RT @Mangan150: Autophagy and aging: Maintaining the proteome through exercise and caloric restriction Don't need to restrict calories, int…
Autophagy and aging: Maintaining the proteome through exercise and caloric restriction Don't need to restrict calories, intermittent fasting will do the job. Exercise powerfully promotes autophagy. Inhibition of autophagy -> premature aging Get on it https://t.co/mTfFrk3Fxx
Autophagy and aging: Maintaining the proteome through exercise and caloric restriction. - PubMed - NCBI https://t.co/F8nqtA0nG5
Exercise and calorie restriction promotes autophagy which in turn enhances longevity https://t.co/A9KM1blE85
Autophagy and aging: Maintaining the proteome through exercise and caloric restriction https://t.co/HbMYhMuvNM
Autophagy and aging: Maintaining the proteome through exercise and caloric restriction/ 2019 https://t.co/7WbDZxVFy5
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