Nat Commun November 2018 PMID 30504855

High throughput ANI analysis of 90K prokaryotic genomes reveals clear species boundaries.

Chirag Jain, Luis M Rodriguez-R, Adam M Phillippy, Konstantinos T Konstantinidis, Srinivas Aluru

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Mentions

Peak: 7 in Mar 2019

across 5 sources since Mar 2019

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37,427

potential audience

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Mar 2019 – Nov 2023

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AI synopsis

What people are saying

The discussions demonstrate strong interest and moderate agreement by emphasizing the importance of the research's results, with phrases like 'reveals clear species boundaries' and references to awards and project team efforts. The tone blends technical acknowledgment with appreciation, reflecting a nuanced engagement with the study's significance.

AgreementModerate agreement

Most discussions recognize the significance of the findings, such as the confirmation of clear species boundaries using FastANI, indicating general agreement with the research.

InterestHigh interest

The posts show high interest, evident from phrases like 'excited' and highlighting awards and new insights, suggesting enthusiasm for the methodology and results.

EngagementModerate engagement

The discussion involves some technical details, such as mentions of genome pairs and ANI thresholds, indicating moderate engagement rather than superficial appreciation.

ImpactModerate impact

The recognition of the FastANI project's achievements and the cross-referencing of its implications suggest that users see the research as having a moderate but meaningful impact on microbial taxonomy and bioinformatics.

Abstract in brief

The study introduces FastANI, a fast and accurate method for calculating Average Nucleotide Identity (ANI) across thousands of genomes, enabling high-resolution taxonomic analysis of prokaryotes.
By applying FastANI to nearly 90,000 genomes from the NCBI database, the research finds a clear genetic discontinuity, supporting distinct species boundaries rather than a continuum of genetic diversity.
The results show that 99.8% of the billions of genome pairs analyzed conform to established ANI thresholds for species classification, indicating that prokaryotic species are well-defined rather than part of a genetic continuum.]

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All mentions

High-throughput ANI Analysis of 90K Prokaryotic Genomes Clarifies Species Boundaries

This study introduces FastANI, a rapid and accurate method for calculating Average Nucleotide Identity across thousands of genomes, revealing clear genetic discontinuities and well-defined prokaryotic species boundaries.

STEM RTCL TV · Jul 4, 2023 29 views

High-throughput ANI Analysis of 90,000 Prokaryotic Genomes Clarifies Species Boundaries

This study introduces FastANI, a fast and accurate method for calculating Average Nucleotide Identity across thousands of genomes. Applying it to nearly 90,000 genomes reveals a clear genetic discontinuity, supporting…

STEM RTCL TV · Nov 1, 2023 21 views

Damien Wells

@damienwells · X

High throughput ANI analysis of 90K prokaryotic genomes reveals clear species boundaries https://t.co/EkR3fwervs @NatureComms

Oct 27, 2022 · 2,628 followers View post →

Niranjan Nagarajan

@NiranjanTW · X

RT @chirgjain: I'm excited to be selected for HPC Achievement Award by @NERSC, for the FastANI project https://t.co/kTWGNyplXD Thanks to…

Oct 26, 2022 · 4 shares · 1,355 followers View post →

Adam Phillippy

@aphillippy · X

RT @chirgjain: I'm excited to be selected for HPC Achievement Award by @NERSC, for the FastANI project https://t.co/kTWGNyplXD Thanks to…

Oct 26, 2022 · 4 shares · 16,414 followers View post →

Jianshu Zhao

@jansue_chao · X

RT @chirgjain: I'm excited to be selected for HPC Achievement Award by @NERSC, for the FastANI project https://t.co/kTWGNyplXD Thanks to…

Oct 26, 2022 · 4 shares · 166 followers View post →

Luis M Rodriguez-R

@_lrr_ · X

RT @chirgjain: I'm excited to be selected for HPC Achievement Award by @NERSC, for the FastANI project https://t.co/kTWGNyplXD Thanks to…

Oct 26, 2022 · 4 shares · 307 followers View post →

Chirag Jain

@chirgjain · X

Oct 26, 2022 · 25 likes · 4 shares · 799 followers View post →

bioRxiv Published

@biorxiv_pubd · X

High-throughput ANI Analysis of 90K Prokaryotic Genomes Reveals Clear Species Boundaries published as: https://t.co/01vOEtV71g @naturecomms #biorxiv

Dec 16, 2020 · 2 likes · 2,905 followers View post →

Tonya Ward

@T_L_Ward · X