The dietary source determines their abundance and composition. Rohm F, Skurk T, Daniel H, Spanier B. Appearance of Di- and Tripeptides in Human Plasma after a Protein Meal Does Not Correlate with PEPT1 Substrate Selectivity. Mol Nutr Food Res. 2019 Mar;63(5):e1801094.
Appearance of Di- and Tripeptides in Human Plasma after a Protein Meal Does Not Correlate with PEPT1 Substrate Selectivity.
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Feb 2024 – Sep 2025Where it's discussed
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Several discussions highlight the importance of dietary sources in determining peptide levels, with mentions that 'the dietary source determines their abundance and composition,' while others reflect an interest in the complex regulation of plasma peptides. The tone suggests curiosity and appreciation for the nuances of the research, though without significant controversy or calls for immediate practical change.
The discussion shows general agreement with the publication, emphasizing the role of dietary sources over PEPT1 selectivity.
Participants demonstrate moderate interest, focusing on mechanisms and the influence of diet on peptide levels.
Comments reflect some depth, referencing the study authors and scientific concepts, but lack substantial debate.
The discussion recognizes that the findings have moderate implications for understanding protein digestion but are not perceived as groundbreaking.
Abstract in brief
- PEPT1's role in absorbing di- and tripeptides from dietary proteins, particularly meat, is not fully understood.
- Changes in plasma levels of various oligopeptides were studied after chicken breast consumption, revealing a complex response of different dipeptides in the blood.
- The presence of dipeptides and tripeptides in blood is influenced not only by PEPT1's specificity but also by their stability against digestive enzymes, emphasizing the importance of the dietary source.
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@edlethor @MaritoMilenio3 @marcos_galperin https://t.co/5rcrh0OcJX
The dietary source determines their abundance and composition. Rohm F, Skurk T, Daniel H, Spanier B. Appearance of Di- and Tripeptides in Human Plasma after a Protein Meal Does Not Correlate with PEPT1 Substrate Selectivity. Mol Nutr Food Res. 2019 Mar;63(5):e1801094.