December 2018 PMID 30526685

Rapid overview of systematic reviews of nocebo effects reported by patients taking placebos in clinical trials.

Jeremy Howick, Rebecca Webster, Nigel Kirby, Kerry Hood

Mentions

129
Peak: 32 in Sep 2023
across 4 sources since Dec 2018

Extended reach

977,055
potential audience

Total likes

2,400

Video views

85,251

Mentions per month

Dec 2018 – Jul 2025

Where it's discussed

  • X / Twitter123 posts
  • News3 articles
  • YouTube2 videos
  • Blogs1 articles

AI synopsis

What people are saying

Overall, discussions exhibit a strong consensus that high rates of adverse events in control groups are due to background rates and nocebo effects, as demonstrated by phrases like 'background rates matter' and 'it's why we use control groups.' The tone remains analytical and supportive, emphasizing the importance of proper trial design, which underscores the recognition of the research's impactful role in clinical practices.

AgreementStrong agreement

Most discussions agree with the study, emphasizing the importance of background rates and control groups to interpret adverse events, showing broad support.

InterestModerate interest

While there is some interest in the implications for clinical trial design, few participants delve deeply into methodological details, indicating moderate engagement.

EngagementModerate engagement

Participants reference the consistent finding that about half of placebo groups report adverse events, with some discussions citing specific statistics and background rates.

ImpactHigh impact

The widespread acknowledgment of the nocebo effect's influence on trial outcomes highlights the significance of these findings for medical research and public health communication.

Abstract in brief

  • This overview synthesizes evidence from 20 systematic reviews involving over 1,200 randomized trials to assess adverse events (AEs) reported by patients taking placebos in clinical trials, revealing that about 49.1% of patients in placebo groups experience AEs.
  • The study found that AEs are more frequently reported in placebo groups (65.1%) compared to untreated groups (42.5%), indicating that not all adverse events are due to natural disease progression, but may be influenced by nocebo effects.
  • Limitations include variability in review quality and a small number of trials with untreated groups, but overall, the findings highlight that AEs in placebo groups are common and contribute to our understanding of nocebo effects in clinical research.]

Top posts

Most liked on X and Bluesky
Vicki Allen Crabb
@crabb_vicki · X

In a meta-analysis of adverse events reported in nocebo trials (they were given a placebo, but think they were getting treated), 50% reported an adverse event, of these, 5% withdrew from the trial. This highlights the importance of a CONTROL group. https://t.co/lbsrhMKt8n https://t.co/QjZRdxBHSR

Sep 15, 2023 · 123 likes · 34 shares · 5,520 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@villagerssn @provaxtexan @LiamKav @ZaynJaffer @DCGreenZone1 @policing_uk @stevenmosher @_mamadeb @Kathmarval @vaxxinesRpoison @tenebra99 @Top_Muppetries @PPALtd @ncdave4life @TonyBaduy @doritmi @AGTCnews @EstesPga @MathewMoisture @richykirsh @SkepticalMutant @FillmoreWhite @DomIsa6 @chickaboy @RailFareWatch @TakethatCt @AcademicShards @mcfunny @llambchops @Tony__Heller @AJL037 @GeoffSchuler @RedSatoshi4 @AndrewLazarus4 @THC1001 @cooljamm55 @luigi_warren @realPitBullDog @Mchael21592783M @krebiozen @murdersquirrel @SeriousSkeptic @DanChesler @GenxlF @AmericanaMinds1 @juan_moment @RobinH00dThe2nd @itsnotallabout2 @Thedaphster39 @Lam37820433 50% of clinical trial participants report adverse events after receiving a placebo. Events happen. It’s the reason we randomize (to make groups comparable) and use a control group (to estimate background risk). https://t.co/lbsrhMKt8n

Oct 13, 2021 · 9 likes · 2 shares · 5,520 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@TDBSubstack @ryanbeed @mcfunny @ShaneAKAProp @NTanzerin @Crazycdn2 @SynthIge @NathanaelYoung @dann58638436 @redheadlass1402 @troydee @JiminyC24 @hoothathuh @SerTophamHatt @TBD77 @dave_odo @thisisnothappen @ptcjoneses @FatalFibers @Marpassion @GiveABJGoToJail @carlsmythe @nicolas_gaboury @Kitty_Grayling @TakethatCt @hansel21_ @EveJackson2011 @CachePast @Joe09396262 @nononsenseat @Orwell2023 @All_Knowing_Bio @rw_christian @LaymansScience @Pkdocker9 @AlBowers1 @cbeckj @Golfergirl2018 @GlenMacafee @BerryTartlet @DaleDarcy4 @VUsuxballs @Sc_ott @real_seeking @mhunt081266 @GMB @PhRMA @CDCgov @elonmusk @Jikkyleaks Welcome to epidemiology. It's hard. Summoning Jikky won't help you. A systematic review found that ~50% of trial recipients who receive a nocebo report an adverse event. Five percent drop out of the trial because of the nocebo. Background rates matter. https://t.co/lbsrhMKt8n

Apr 26, 2023 · 9 likes · 5,520 followers View post →
Kurt cobain miracle baby
@BabyKurt1795 · X

@rajakz3 https://t.co/uzMQCHrMBS Ppl should watch this video and realize how safe Finasteride actually is I wish I got on it sooner and prevented more of my loss instead of playing catch up with minoxidil now

Jul 12, 2025 · 8 likes · 3 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@Cannon732501331 @cappsie @Creativologist @TorySnyc @NoGlobalist778 @Roper_Lab @EugeneBu @CaryDavid722 @Lorenzo7127 @Monstercoyliar @PatrickSquirrel @trillionofcells @SkepticalMutant @AcampbelTeacher @ChrisJohnsonMD @iXeno @ktibus @higgsri @davideyoungmd @EdwardDS15 @FillmoreWhite @dirk_fasshauer @VickiCoyle10019 @FUDyou2 @mcfunny @Earthdriver @smith_john55 @TMGFlorida @TheCrystalBrian @ScooterScience @RndmStreetMedic @DebraBr81576310 @JordanA8156 @BlueLionBlog @ScotMAGA24 @vstefans @judysimpson222 @TheFrankmanMN @Apotheosis1974 @FrankDElia7 @krebiozen @Anymous84861064 @Awithonelison @shallit43 @natedoromal @gavleeham @ToBornin @NewSeasonsSpa @mjtimber2 @Humans_R_Free In a meta-analysis. 50% of placebo recipients report an adverse event during a trial. Of these, 5% withdrawal from the trial. This emphasizes why we use a control group, something Siri doesn’t seem to get. https://t.co/l

Sep 6, 2024 · 6 likes · 1 share · 5,520 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@dazg_11 @FrankDElia7 @krebiozen @RefusenikRed @doritmi @mcfunny @FormerAntivax @100Dianne @Kathmarval @TonyBaduy @1_TMF_ @ScepticalAussie @SkepticalMutant @runningrabbit_1 @groin_hammer @marcus66508078 @DeoOmniaVincit @littleLishka @handmadekathy @joltdude @AndrewLazarus4 @nia3in @swedishchf @LandmineLenny @Just4TheCause @GeneTherapy68 @hauxton @TakethatCt @WendyOrent @MsTrixter @provaxtexan @vinnumbskull @GeoffSchuler @PaulVCooper1 @Tawdge @LauraDekker1 @_mamadeb @emartinez78987 @bgspence @MAhealthforkids @pleasetellmeM @TinFoilAwards @Angel_13_Rising @7_DSSEVEN @JamesElijahMill @Charitable_Fury @PriestofBaal @Aly_Meek @jkellyca @jengleruk No. Every pharmaceutical/biological can elicit an adverse event, even placebos and saline. Why? Because most events have a background rate (headache, stomachs, etc) and these events may be unrelated to the intervention. https://t.co/lbsrhMKt8n

Jul 16, 2021 · 6 likes · 2 shares · 5,520 followers View post →

All mentions

Kurt cobain miracle baby
@BabyKurt1795 · X

@rajakz3 https://t.co/uzMQCHrMBS Ppl should watch this video and realize how safe Finasteride actually is I wish I got on it sooner and prevented more of my loss instead of playing catch up with minoxidil now

Jul 12, 2025 · 8 likes · 3 followers View post →
Kurt cobain miracle baby
@BabyKurt1795 · X

https://t.co/uzMQCHrMBS Best video disproving the lies over finasteride and how it actually works

Jul 12, 2025 · 3 followers View post →
Kurt cobain miracle baby
@BabyKurt1795 · X

@DimitriRunes @MinModulation https://t.co/uzMQCHrMBS This is the best YouTube channel over hairloss and disproving the myths

Jul 12, 2025 · 4 likes · 3 followers View post →
'
@Dexter__m27 · X

@Susisidee @7ebat_lmlouk https://t.co/gzL6endvWj

Dec 15, 2024 · 1 like · 141 followers View post →
'
@Dexter__m27 · X

@Susisidee @7ebat_lmlouk إلا باغي تثقف راسك شوف هاد خوتنا فاهمين فهادشي https://t.co/nF0yiv2ZKo https://t.co/fZZ6J070pS

Dec 15, 2024 · 1 like · 141 followers View post →
Dr Anne Condon
@SkepticalMutant · X

RT @crabb_vicki: @Cannon732501331 @cappsie @Creativologist @TorySnyc @NoGlobalist778 @Roper_Lab @EugeneBu @CaryDavid722 @Lorenzo7127 @Monst…

Sep 6, 2024 · 1 share · 1,635 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@Cannon732501331 @cappsie @Creativologist @TorySnyc @NoGlobalist778 @Roper_Lab @EugeneBu @CaryDavid722 @Lorenzo7127 @Monstercoyliar @PatrickSquirrel @trillionofcells @SkepticalMutant @AcampbelTeacher @ChrisJohnsonMD @iXeno @ktibus @higgsri @davideyoungmd @EdwardDS15 @FillmoreWhite @dirk_fasshauer @VickiCoyle10019 @FUDyou2 @mcfunny @Earthdriver @smith_john55 @TMGFlorida @TheCrystalBrian @ScooterScience @RndmStreetMedic @DebraBr81576310 @JordanA8156 @BlueLionBlog @ScotMAGA24 @vstefans @judysimpson222 @TheFrankmanMN @Apotheosis1974 @FrankDElia7 @krebiozen @Anymous84861064 @Awithonelison @shallit43 @natedoromal @gavleeham @ToBornin @NewSeasonsSpa @mjtimber2 @Humans_R_Free In a meta-analysis. 50% of placebo recipients report an adverse event during a trial. Of these, 5% withdrawal from the trial. This emphasizes why we use a control group, something Siri doesn’t seem to get. https://t.co/l

Sep 6, 2024 · 6 likes · 1 share · 5,520 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@mothrfunkr @ajrimmer42 @FactsAreGood You’re incorrect. It says it in the title. https://t.co/lbsrhMKt8n

Aug 31, 2024 · 2 likes · 5,520 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@fcktrudeau99 @PeterDaszak Where’s the data from the control group? Which of these outcomes don’t have a background rate? A meta-analysis found that ~50% of clinical trial participants who receive a placebo, experience an adverse events, even death. https://t.co/lbsrhMKt8n

Aug 31, 2024 · 5,520 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@PatrickSquirrel @SkepticalMutant @cappsie @CaryDavid722 @Lorenzo7127 @BurgerLab12 @mcfunny @JoseRam55630637 @swedishchf @JonKnudson89269 @axoplasmicgap @Alex_on_A14 @Catinthesun24 @trillionofcells @AlBowers1 @exohalophiles @Monstercoyliar @drbrignall @Roper_Lab @ktibus @iXeno @higgsri @ChrisJohnsonMD @SecedeFromFools @jtmayes3 @TorySnyc @dirk_fasshauer @RonMortimer3 @lasikeyecenter1 @Hanky1844607 @davideyoungmd @Awithonelison @NoGlobalist778 @EugeneBu @AcampbelTeacher @EdwardDS15 @FillmoreWhite @VickiCoyle10019 @FUDyou2 @Earthdriver @smith_john55 @TMGFlorida @TheCrystalBrian @ScooterScience @RndmStreetMedic @DebraBr81576310 @JordanA8156 @BlueLionBlog @ScotMAGA24 @vstefans A systematic review found that 50% of participants who receive a placebo during an RCT, experience an adverse event. Of these, 5% withdraw from the trial due to an adverse event. I hope this illustrates why you need a

Aug 24, 2024 · 3 likes · 5,520 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@Megalodon_2nd A meta-analysis of adverse events reported in nocebo trials (given a placebo but told they were given the intervention) found that 50% reported an adverse event. 5% quit the trial. https://t.co/lbsrhMKt8n

Jun 3, 2024 · 5,520 followers View post →
RI Bio
@WeAreRIBio · X

RT @JeremyHowick: @nytimes letter by @mh_bernstein reports that #vaccine hesitancy could be because of the #nocebo effect: https://t.co/qpD…

Apr 29, 2024 · 2 shares · 744 followers View post →
Mike Bernstein
@mh_bernstein · X

RT @JeremyHowick: @nytimes letter by @mh_bernstein reports that #vaccine hesitancy could be because of the #nocebo effect: https://t.co/qpD…

Mar 27, 2024 · 2 shares · 210 followers View post →
Jeremy Howick
@JeremyHowick · X

@nytimes letter by @mh_bernstein reports that #vaccine hesitancy could be because of the #nocebo effect: https://t.co/qpDx3hzq3c Our study found that half of people in clinical trials who take #placebos experience at least one negative side effect. https://t.co/6D60IEMDwT

Mar 27, 2024 · 2 likes · 2 shares · 4,764 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@alexgrenier @HeyNurseKat @AnnaSova17 @Therebedragons1 @Debunk_the_Funk @thevivafrei I’m referring to the control group. They can’t verify it’s related to the vaccine other than temporally. In a systematic review of RCTs, ~ 50% of nocebo recipients reported an AE, 5% withdrew from the trial. It’s why we use a control. https://t.co/lbsrhMKt8n

Jan 27, 2024 · 1 like · 5,520 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@GordanBobic @goc1978 @k10Aug @TakethatCt @SamanthaFoxy1 @Danny459673 @basil_ireton @Monstercoyliar @FatEmperor @rw_christian @Mr_Magoo5 @krebiozen @Scary7Dr @mcfunny @FreedomReigns2 @Top_Muppetries @jilel76 @CoralBlob @pawley_robert @SoiferErica @LiamKav @Izzitreally2 @dave_odo @Pouldeau61 @ghoppe @Nicoleg425 @Mchael21592783M @FUDyou2 @Alex_on_A14 @provaxtexan @carlsmythe @MsTrixter @BurgerLab12 @TierraHenson @bolt_carl @_mamadeb @doritmi @NottaLeftard @policing_uk @FrankDElia7 @SkepticalMutant @NEvadto @stevenmosher @Suesue2point0 @DPBeachNY @vault_code @MicktheStick99 @Megalodon_16 @JimSatone @DapperScyphozoa Incorrect. A meta-analysis of nocebo trials found that 50% of nocebo (a placebo where the participant is told they are getting the intervention but actually get the placebo) recipients report an adverse event. Of these, ~ 10% withdraw from the trial. https://t.co/lbsrhML0XV

Dec 20, 2023 · 2 likes · 5,520 followers View post →
Julie Norton
@julienorton22 · X

RT @JeremyHowick: Congratulations @AlburyCharlotte! Optimistic language does indeed make a difference: https://t.co/SIaTnYlUns, and negativ…

Nov 10, 2023 · 1 share · 600 followers View post →
Jeremy Howick
@JeremyHowick · X

Congratulations @AlburyCharlotte! Optimistic language does indeed make a difference: https://t.co/SIaTnYlUns, and negative language can harm: https://t.co/6D60IENbmr https://t.co/mTxKLHRrGq

Nov 8, 2023 · 2 likes · 1 share · 4,764 followers View post →
ekkJackYouLate
@ekkJackYouLate · X

@YourNightmareIN @Happy_Long_Life @bryan_johnson https://t.co/GwXGrb3u0u

Oct 14, 2023 · 1 like · 527 followers View post →
JM Pienaar
@PienaarJm · X

RT @crabb_vicki: In a meta-analysis of adverse events reported in nocebo trials (they were given a placebo, but think they were getting tre…

Sep 16, 2023 · 34 shares · 612 followers View post →
Kat(rina McD)
@krazykitkatm · X

RT @crabb_vicki: In a meta-analysis of adverse events reported in nocebo trials (they were given a placebo, but think they were getting tre…

Sep 16, 2023 · 34 shares · 901 followers View post →
Ale
@Alex_on_A14 · X

RT @crabb_vicki: In a meta-analysis of adverse events reported in nocebo trials (they were given a placebo, but think they were getting tre…

Sep 16, 2023 · 34 shares · 2,054 followers View post →
Why?
@whykeepitup · X

RT @crabb_vicki: In a meta-analysis of adverse events reported in nocebo trials (they were given a placebo, but think they were getting tre…

Sep 16, 2023 · 34 shares · 1,838 followers View post →
Peekaboo
@PaPeekaboo · X

RT @crabb_vicki: In a meta-analysis of adverse events reported in nocebo trials (they were given a placebo, but think they were getting tre…

Sep 16, 2023 · 34 shares · 828 followers View post →
John Graham-Hart
@JohnGHart · X

RT @crabb_vicki: In a meta-analysis of adverse events reported in nocebo trials (they were given a placebo, but think they were getting tre…

Sep 16, 2023 · 34 shares · 12,154 followers View post →
anti_disease
@anti_disease · X

RT @crabb_vicki: In a meta-analysis of adverse events reported in nocebo trials (they were given a placebo, but think they were getting tre…

Sep 16, 2023 · 34 shares · 1,658 followers View post →
Black Lives Matter (+we still have kids in cages)
@OrigamiFrog1 · X

RT @crabb_vicki: In a meta-analysis of adverse events reported in nocebo trials (they were given a placebo, but think they were getting tre…

Sep 16, 2023 · 34 shares · 40 followers View post →
Joe Schmoe
@Joe_Schmoe337 · X

RT @crabb_vicki: In a meta-analysis of adverse events reported in nocebo trials (they were given a placebo, but think they were getting tre…

Sep 15, 2023 · 34 shares · 348 followers View post →
(((Dr Aust)))
@Dr_Aust_PhD · X

RT @crabb_vicki: In a meta-analysis of adverse events reported in nocebo trials (they were given a placebo, but think they were getting tre…

Sep 15, 2023 · 34 shares · 2,415 followers View post →
Jessica Gray
@JessTheGray · X

RT @crabb_vicki: In a meta-analysis of adverse events reported in nocebo trials (they were given a placebo, but think they were getting tre…

Sep 15, 2023 · 34 shares · 156 followers View post →
Mike Babulic
@MikeBabulic · X

RT @crabb_vicki: In a meta-analysis of adverse events reported in nocebo trials (they were given a placebo, but think they were getting tre…

Sep 15, 2023 · 34 shares · 446 followers View post →
Kat
@katstreams_ · X

RT @crabb_vicki: In a meta-analysis of adverse events reported in nocebo trials (they were given a placebo, but think they were getting tre…

Sep 15, 2023 · 34 shares · 196 followers View post →
Clayton Robins
@ClaytonRobins · X

RT @crabb_vicki: In a meta-analysis of adverse events reported in nocebo trials (they were given a placebo, but think they were getting tre…

Sep 15, 2023 · 34 shares · 5,587 followers View post →
healthcareworkers should model masking
@Lynncabin · X

RT @crabb_vicki: In a meta-analysis of adverse events reported in nocebo trials (they were given a placebo, but think they were getting tre…

Sep 15, 2023 · 34 shares · 2,148 followers View post →
Wilma Van Sant
@WilmaVanSant · X

RT @crabb_vicki: In a meta-analysis of adverse events reported in nocebo trials (they were given a placebo, but think they were getting tre…

Sep 15, 2023 · 34 shares · 2,289 followers View post →
ReluctantActivist
@ReluctantActvst · X

RT @crabb_vicki: In a meta-analysis of adverse events reported in nocebo trials (they were given a placebo, but think they were getting tre…

Sep 15, 2023 · 34 shares · 966 followers View post →
Green Party Communist
@Sarah_H115 · X

RT @crabb_vicki: In a meta-analysis of adverse events reported in nocebo trials (they were given a placebo, but think they were getting tre…

Sep 15, 2023 · 34 shares · 793 followers View post →
SomeCallMeLaz (BSc)
@SomeCallMeLaz · X

RT @crabb_vicki: In a meta-analysis of adverse events reported in nocebo trials (they were given a placebo, but think they were getting tre…

Sep 15, 2023 · 34 shares · 606 followers View post →
Jennifer Gunter
@DrJenGunter · X

RT @crabb_vicki: In a meta-analysis of adverse events reported in nocebo trials (they were given a placebo, but think they were getting tre…

Sep 15, 2023 · 34 shares · 317,027 followers View post →
@namelessMD145
@UnknownMD145 · X

RT @crabb_vicki: In a meta-analysis of adverse events reported in nocebo trials (they were given a placebo, but think they were getting tre…

Sep 15, 2023 · 34 shares · 147 followers View post →
Carl J
@Plus_haut · X

RT @crabb_vicki: In a meta-analysis of adverse events reported in nocebo trials (they were given a placebo, but think they were getting tre…

Sep 15, 2023 · 34 shares · 739 followers View post →
Frank Han MD
@han_francis · X

RT @crabb_vicki: In a meta-analysis of adverse events reported in nocebo trials (they were given a placebo, but think they were getting tre…

Sep 15, 2023 · 34 shares · 4,748 followers View post →
Cristina
@TampaWoman1965 · X

RT @crabb_vicki: In a meta-analysis of adverse events reported in nocebo trials (they were given a placebo, but think they were getting tre…

Sep 15, 2023 · 34 shares · 3,435 followers View post →
Preston Bobo, Chemgod
@Navarp · X

RT @crabb_vicki: In a meta-analysis of adverse events reported in nocebo trials (they were given a placebo, but think they were getting tre…

Sep 15, 2023 · 34 shares · 2,522 followers View post →
Segl
@Segl03966132 · X

RT @crabb_vicki: In a meta-analysis of adverse events reported in nocebo trials (they were given a placebo, but think they were getting tre…

Sep 15, 2023 · 34 shares · 470 followers View post →
(((Liz Ditz))). Mask up, y'all. Viruses are real.
@lizditz · X

RT @crabb_vicki: In a meta-analysis of adverse events reported in nocebo trials (they were given a placebo, but think they were getting tre…

Sep 15, 2023 · 34 shares · 10,464 followers View post →
Ⓘⓡⓘⓝⓐ
@imalinow · X

RT @crabb_vicki: In a meta-analysis of adverse events reported in nocebo trials (they were given a placebo, but think they were getting tre…

Sep 15, 2023 · 34 shares · 877 followers View post →
CosmosMom
@CosmosMom1 · X

RT @crabb_vicki: In a meta-analysis of adverse events reported in nocebo trials (they were given a placebo, but think they were getting tre…

Sep 15, 2023 · 34 shares · 769 followers View post →
(((whatever)))
@kath2cats · X

RT @crabb_vicki: In a meta-analysis of adverse events reported in nocebo trials (they were given a placebo, but think they were getting tre…

Sep 15, 2023 · 34 shares · 1,402 followers View post →
John
@joltdude · X

RT @crabb_vicki: In a meta-analysis of adverse events reported in nocebo trials (they were given a placebo, but think they were getting tre…

Sep 15, 2023 · 34 shares · 2,997 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

In a meta-analysis of adverse events reported in nocebo trials (they were given a placebo, but think they were getting treated), 50% reported an adverse event, of these, 5% withdrew from the trial. This highlights the importance of a CONTROL group. https://t.co/lbsrhMKt8n https://t.co/QjZRdxBHSR

Sep 15, 2023 · 123 likes · 34 shares · 5,520 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@RB84509962 In a meta-analysis of adverse events reported in nocebo trials (they were given a placebo, but think they were getting treated), 50% reported an adverse event, of these, 5% withdrew from the trial. This highlights the importance of a control group. /2 https://t.co/lbsrhMKt8n

Aug 14, 2023 · 5,520 followers View post →
Wendy Burn CBE
@wendyburn · X

@Gus06216996 @DBDouble @psychunseen @awaisaftab @jonathanstea @ProfRobHoward @DrHowardLiu @paulsummergrad @evolutionarypsy @shayla__love They do actually: https://t.co/yqyhsEwIaU

Jun 8, 2023 · 2 likes · 27,322 followers View post →
Jono Broad
@JonoBroad · X

RT @JeremyHowick: TWO BACKGROUND PROBLEMS 1. The way benefit and harm info is shared varies : most explain harms clearly, a third do not m…

May 31, 2023 · 1 share · 777 followers View post →
Jeremy Howick
@JeremyHowick · X

TWO BACKGROUND PROBLEMS 1. The way benefit and harm info is shared varies : most explain harms clearly, a third do not mention any potential benefits. https://t.co/1MTqLCKYq4 2. Unbalanced benefit/harm information can cause “nocebo” effects: https://t.co/6D60IEMDwT

May 31, 2023 · 1 like · 1 share · 4,764 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@TDBSubstack @ryanbeed @mcfunny @ShaneAKAProp @NTanzerin @Crazycdn2 @SynthIge @NathanaelYoung @dann58638436 @redheadlass1402 @troydee @JiminyC24 @hoothathuh @SerTophamHatt @TBD77 @dave_odo @thisisnothappen @ptcjoneses @FatalFibers @Marpassion @GiveABJGoToJail @carlsmythe @nicolas_gaboury @Kitty_Grayling @TakethatCt @hansel21_ @EveJackson2011 @CachePast @Joe09396262 @nononsenseat @Orwell2023 @All_Knowing_Bio @rw_christian @LaymansScience @Pkdocker9 @AlBowers1 @cbeckj @Golfergirl2018 @GlenMacafee @BerryTartlet @DaleDarcy4 @VUsuxballs @Sc_ott @real_seeking @mhunt081266 @GMB @PhRMA @CDCgov @elonmusk @Jikkyleaks Welcome to epidemiology. It's hard. Summoning Jikky won't help you. A systematic review found that ~50% of trial recipients who receive a nocebo report an adverse event. Five percent drop out of the trial because of the nocebo. Background rates matter. https://t.co/lbsrhMKt8n

Apr 26, 2023 · 9 likes · 5,520 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@ptcjoneses @cbeckj @mhunt081266 @maryloupatey @davey3483 @DarthPlagueis84 @nicolas_gaboury @troydee @ryanbeed @Its_Agenda_2030 @TBD77 @CAS2328 @carlsmythe @leelasik @Hampson14Jane @hoothathuh @5shezz4 @0800_KSMY_ASS @Kitty_Grayling @SSZ1967 @MrDannyTeal @JiminyC24 @Cubanigar @Joe09396262 @CachePast @niall_joe @Amber84280581 @maggiemay_313 @villagerssn @ammejo1 @InCytometry @MFuzzbox @TakethatCt @djchicus @dann58638436 @NathanaelYoung @Agent2Dark @VikingRefusenik @ShockTraumaRN @CHSdoctor @jilel76 @MrQuantity @rw_christian @RayDoobay @sickofitall2222 @MinnesotaExpat @basil_ireton @The_Ouroboros__ @PLHartungRN @BoredofFools More than 50% of nocebo recipients report adverse events during the conduct of a clinical trial (~5% withdraw from the trial). This is the reason why we use a control group. https://t.co/lbsrhN23ZV

Dec 10, 2022 · 5,520 followers View post →
Poppyjuice
@Poppyjuice · X

@DrAseemMalhotra https://t.co/58Wumjz3W8 https://t.co/z3vvKGAZt9

Dec 5, 2022 · 7,730 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@ShaneAKAProp @DrMohammadIAdi1 50% of placebo (nocebo) recipients experience an adverse event during a clinical trial. Some severe enough to withdraw from a trial. It’s why we use a control group. These events occur regardless of the treatment assignment. https://t.co/lbsrhML0XV

Nov 9, 2022 · 5 likes · 5,520 followers View post →
Jenny Preston (Mrs D’Arcy in personal life)
@jen_preston1 · X

RT @JeremyHowick: Our study was motivated by two background studies: 1: 50% of patients who take #placebo treatments report #side effects.…

Oct 12, 2022 · 2 shares · 1,959 followers View post →
Richard Haggerty
@RichardHaggerty · X

RT @JeremyHowick: Our study was motivated by two background studies: 1: 50% of patients who take #placebo treatments report #side effects.…

Oct 11, 2022 · 2 shares · 383 followers View post →
Jeremy Howick
@JeremyHowick · X

Our study was motivated by two background studies: 1: 50% of patients who take #placebo treatments report #side effects. Some of these side-effects are #nocebo effects, caused by describing the side-effects in an unnecessarily scary way: https://t.co/6D60IENbmr @beccakwebster

Oct 11, 2022 · 3 likes · 2 shares · 4,764 followers View post →
Jeremy Howick
@JeremyHowick · X

Subject to the chicken or egg caveat, this study suggests that the severity of some symptoms seems to be influenced by anxiety. https://t.co/6D60IEMDwT #nocebo #placebo #anxiety #stress #worry @kube_tobias @LironRozenkrant

Sep 8, 2022 · 1 like · 4,764 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@reneaafko @doritmi @scientistabe @HeyNurseKat @AshleyFoxRPN @LMCERL123456 @Answers4Sean @Puppieskitts @DougEyolfson @P_McCulloughMD Causality? More than 50% of nocebo recipients experience an adverse event during the conduct of a RCT. Are you saying these nocebos are causal to these events? https://t.co/lbsrhMKt8n

Sep 5, 2022 · 2 likes · 5,520 followers View post →
(((Liz Ditz))). Mask up, y'all. Viruses are real.
@lizditz · X

RT @crabb_vicki: @covidscam2 @_mamadeb @DrFluffyPants3 @doritmi @michellespj @handmadekathy @teaze_r @RandomKiwiUS @MsTrixter @goodlobster1…

Jul 30, 2022 · 1 share · 10,464 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@covidscam2 @_mamadeb @DrFluffyPants3 @doritmi @michellespj @handmadekathy @teaze_r @RandomKiwiUS @MsTrixter @goodlobster1 @AndrewLazarus4 @TheFrankmanMN @troydee @flitesurgn @Patriot4517 @avocato_bob @kevinault @Strange_G @JestrBob @swedishchf @GeoffSchuler @provaxtexan @Awithonelison @mcfunny @LightControl2 @KatLaRue7 @StahpL @Just4TheCause @regina1775 @KStateTurk @StopCensorship7 @Golfergirl2018 @repr13 @InsideVaccines @fuiwontdowhatu1 @SwordtheChemist @hendog451 @runhack @jkellyca @Charitable_Fury @bigherm3953 @susan_welch7 @NzFubar @PatriotNz2022 @PowderPuffPlay @Dame__Jane @DavisAndrew88 @kiwiwayne2 @SaulGoodman1971 @hakanzjp2 Almost 50% of placebo recipients reported an adverse event during the conduct of a trial. About 5% report the event was serious enough to withdraw from the trial. This is “simple science”, right? https://t.co/lbsrhMKt8n

Jul 26, 2022 · 2 likes · 1 share · 5,520 followers View post →
Mony Likes Science and Facts ✡️ ⚓⚖️
@monyro5 · X

RT @crabb_vicki: @villagerssn @provaxtexan @LiamKav @ZaynJaffer @DCGreenZone1 @policing_uk @stevenmosher @_mamadeb @Kathmarval @vaxxinesRpo…

Jun 8, 2022 · 2 shares · 8,605 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@AnabelVictor1 @CharlieGordon20 @mcfunny @volpiranyas @krebiozen @absolutelyallan @CallMeEOnly @Megalodon_16 @SkepticalMutant @carlsmythe @Monstercoyliar @JTylerHagen @ZaynJaffer @quigley_jesse @FrankDElia7 @Suesue2point0 @vault_code @provaxtexan @policing_uk @Top_Muppetries @MicktheStick99 @TakethatCt @SirGorden @AndrewLazarus4 @CoralBlob @dave_odo @JimSatone @libliars @DapperScyphozoa @PTUK_US @AnzacMegan @LarcombePeter @doritmi @BurgerLab12 @FrancescoPanch0 @_mamadeb @slemar_ @JacobSp00635589 @4Freedoms4All @quesnel_john @i_am_joli_anne @AGoldsmithEsq @stevenmosher @LiamKav @GMACVHHH @alexcampbell @VacSafety @vaxreports1 @VaxInjuries @theysayitsrare 50% of placebo recipients report adverse events during the conduct of a clinical trial. Are you saying placebos cause adverse events? There’s a reason we use control groups. https://t.co/lbsrhMKt8n

Apr 8, 2022 · 1 like · 5,520 followers View post →
Dr Anne Condon
@SkepticalMutant · X

RT @crabb_vicki: @isa_picard @handmadekathy @4thEchelon22 @FrankDElia7 @iXeno @TruthTwt @ChrisAndrews88 @Juanita87722370 @foofdawg @HawkInA…

Mar 27, 2022 · 2 shares · 1,635 followers View post →
(((Liz Ditz))). Mask up, y'all. Viruses are real.
@lizditz · X

RT @crabb_vicki: @isa_picard @handmadekathy @4thEchelon22 @FrankDElia7 @iXeno @TruthTwt @ChrisAndrews88 @Juanita87722370 @foofdawg @HawkInA…

Mar 27, 2022 · 2 shares · 10,464 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@isa_picard @handmadekathy @4thEchelon22 @FrankDElia7 @iXeno @TruthTwt @ChrisAndrews88 @Juanita87722370 @foofdawg @HawkInATX @krebiozen @doritmi @Kathmarval @keithccurtis @sapienist @BafienMorin @MsTrixter @ChrisJohnsonMD @ktibus @TinFoilAwards @mcfunny @s21519 @F250Roush @SassyGirlD1 @mrhawkes @BGLTHMND @ThomasHarrigan8 @TheFrankmanMN @BigBruce1972 @John010708 @SkepticalMutant @Monstercoyliar @lewbloch @BlueLionBlog @somethinsomethi @cappsie @lizditz @dogdownlockdown @natedoromal @GrammarianJoe @SirSydneyCamm @KitemanArgues @SHurrell1 @Rklawton @Skeptiguy1 @phil_luttazi @alisonpalk @WendyOrent @khan_we_kick_it @WaitingForPerot Tell us what "statistical significance" means. Are you saying adverse events don't occur in placebo controls? Wouldn't you be more interested in the difference between the groups? (With the exception of anaphylaxis) Are you sure you read the studies? https://t.c

Mar 27, 2022 · 2 likes · 2 shares · 5,520 followers View post →
Purple Dragon Shill ♿️
@PurpleDragonS40 · X

RT @crabb_vicki: @clownworld_bobo @WaitingForPerot @quesnel_john @CallMeEOnly @slemar_ @AndrewLazarus4 @Monstercoyliar @CharlieGordon20 @Su…

Mar 4, 2022 · 1 share · 5,127 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@clownworld_bobo @WaitingForPerot @quesnel_john @CallMeEOnly @slemar_ @AndrewLazarus4 @Monstercoyliar @CharlieGordon20 @Suesue2point0 @FrankDElia7 @melissa94307909 @LiamKav @AutisticShill @AdamMaybe3 @Top_Muppetries @_mamadeb @CoralBlob @provaxtexan @NaomitimT @volpiranyas @Mchael21592783M @DCGreenZone1 @EstesPga @i_am_joli_anne @AGoldsmithEsq @mcfunny @GMACVHHH @RadRyderX @quigley_jesse @ghoppe @wendy_Lynnette @TakethatCt @ZaynJaffer @JustPlaying2Win @SkepticalMutant @tenebra99 @gobantwo2 @doritmi @stevenmosher @Kathmarval @JawKneeFaiv @MickusDickus @policing_uk @BrockKrause @dodi_rains @carlsmythe @RenfieldThomas @TonyBaduy @ncdave4life Wait, are you claiming there are no adverse events after vaccine administration? 50% of placebo recipients report an adverse event during the conduct of a trial. Are you saying placebos caused these events? https://t.co/lbsrhMKt8n

Mar 4, 2022 · 4 likes · 1 share · 5,520 followers View post →
Frank D’Elia
@FrankDElia7 · X

RT @crabb_vicki: @Top_Muppetries @pete988007766 @jtmayes3 @greenboat @quigley_jesse @melissa94307909 @Kathmarval @AndrewLazarus4 @Skeptical…

Mar 2, 2022 · 1 share · 2,696 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@Top_Muppetries @pete988007766 @jtmayes3 @greenboat @quigley_jesse @melissa94307909 @Kathmarval @AndrewLazarus4 @SkepticalMutant @ZaynJaffer @_mamadeb @mcfunny @factode305 @TakethatCt @MKMCGLONE @doritmi @katieorourke78 @hippocritus @swedishchf @Alaskacryptogi1 @TonyBaduy @carlsmythe @JonInTn1 @FrankDElia7 @WendyOrent @volpiranyas @wendy_Lynnette @ghoppe @AGoldsmithEsq @desertrosekathy @Monstercoyliar @foofdawg @Mchael21592783M @stevenmosher @DCGreenZone1 @provaxtexan @infinitebritt @tenebra99 @i_am_joli_anne @CoralBlob @LiamKav @clownworld_bobo @docstardust @JustPlaying2Win @EstesPga @gobantwo2 @JawKneeFaiv @MickusDickus @policing_uk @BrockKrause Right? Life still happens. We want to know is this "life happening" or is this related to the vaccine? 50% of placebo recipients report an AE during the conduct of a trial. About 5% of these AEs result in placebo recipients withdrawing from a

Mar 2, 2022 · 4 likes · 1 share · 5,520 followers View post →
Frank D’Elia
@FrankDElia7 · X

RT @crabb_vicki: @EstesPga @Monstercoyliar @provaxtexan @WendyOrent @SkepticalMutant @CharlieGordon20 @CoralBlob @slemar_ @CallMeEOnly @Top…

Feb 12, 2022 · 2 shares · 2,696 followers View post →
Dr Anne Condon
@SkepticalMutant · X

RT @crabb_vicki: @EstesPga @Monstercoyliar @provaxtexan @WendyOrent @SkepticalMutant @CharlieGordon20 @CoralBlob @slemar_ @CallMeEOnly @Top…

Feb 12, 2022 · 2 shares · 1,635 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@EstesPga @Monstercoyliar @provaxtexan @WendyOrent @SkepticalMutant @CharlieGordon20 @CoralBlob @slemar_ @CallMeEOnly @Top_Muppetries @DCGreenZone1 @LiamKav @volpiranyas @i_am_joli_anne @AGoldsmithEsq @mcfunny @GMACVHHH @Suesue2point0 @RadRyderX @FrankDElia7 @_mamadeb @AndrewLazarus4 @quigley_jesse @quesnel_john @ghoppe @wendy_Lynnette @clownworld_bobo @TakethatCt @ZaynJaffer @Mchael21592783M @JustPlaying2Win @tenebra99 @gobantwo2 @melissa94307909 @MdRisette @doritmi @stevenmosher @Kathmarval @JawKneeFaiv @MickusDickus @policing_uk @BrockKrause @dodi_rains @carlsmythe @RenfieldThomas @TonyBaduy @ncdave4life @indyymac @Kolyin @diederikdk 50% of placebo recipients in RCTs report adverse events, these events result in ~10% withdrawing from the trials. https://t.co/lbsrhMKt8n

Feb 12, 2022 · 2 likes · 2 shares · 5,520 followers View post →
Michael P. Hengartner, PhD
@HengartnerMP · X

@tkaiser_science @westwoodsam1 @PloederlM See this: https://t.co/WdsegMdKyJ But also: https://t.co/cLaGOSlCvy

Feb 9, 2022 · 2 likes · 8,061 followers View post →
Jacques Sapir
@russeurope · X

RT @russeurope: (III) Voir aussi : Howick J,Webster R, Kirby N, Hood K. « Rapid overview of systematic reviews of nocebo effects reported b…

Jan 24, 2022 · 2 shares · 54,858 followers View post →
JrmieJ
@JrmieJ · X

RT @russeurope: (III) Voir aussi : Howick J,Webster R, Kirby N, Hood K. « Rapid overview of systematic reviews of nocebo effects reported b…

Jan 24, 2022 · 2 shares · 989 followers View post →
Jacques Sapir
@russeurope · X

(III) Voir aussi : Howick J,Webster R, Kirby N, Hood K. « Rapid overview of systematic reviews of nocebo effects reported by patients taking placebos in clinical trials », in Trials. 2018, vol.19, (n°1) p. 674

Jan 24, 2022 · 3 likes · 2 shares · 54,858 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@DivergentNoire @tenebra99 @FiorediNotte33 If 50% of placebo recipients report adverse events during the course of a clinical trial, how did you determine the event was related to the intervention? It's the reason we use a control group. https://t.co/lbsrhMKt8n

Jan 5, 2022 · 1 like · 5,520 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@ZaynJaffer @MickusDickus @AndrewLazarus4 @JawKneeFaiv @stevenmosher @Mchael21592783M @SkepticalMutant @policing_uk @EstesPga @AGoldsmithEsq @mcfunny @MdRisette @CoralBlob @Monstercoyliar @melissa94307909 @BrockKrause @doritmi @dodi_rains @Top_Muppetries @DCGreenZone1 @carlsmythe @RenfieldThomas @TakethatCt @FrankDElia7 @provaxtexan @tenebra99 @TonyBaduy @ncdave4life @indyymac @quigley_jesse @Kolyin @diederikdk @_mamadeb @gobantwo2 @ghoppe @AndyMac84956921 @LiamKav @SpookyJay36 @BichonAtLaw @deNutrients @floraoddchild @Suesue2point0 @CharaStone6 @chickaboy @smyl2day @AcademicShards @ConsequentialBr @Kathmarval @Tony__Heller @MarkReady47 ~50% of all placebo recipients report an adverse event during the conduct of a clinical trial. Does that mean the placebo caused the event? No, but these events do have background rates. The control group provides an estimate of the rate. /2 https://t.co

Dec 30, 2021 · 2 likes · 5,520 followers View post →
Humanist
@pawley_robert · X

RT @crabb_vicki: @CoryRove @mcfunny @Lance_A_Wilkins @MdRisette @ChrisJohnsonMD @pawley_robert @judysimpson222 @Bebert701 @TierraHenson @Ch…

Dec 22, 2021 · 1 share · 2,079 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@CoryRove @mcfunny @Lance_A_Wilkins @MdRisette @ChrisJohnsonMD @pawley_robert @judysimpson222 @Bebert701 @TierraHenson @Chris_F_Carson @BurgerLab12 @frugalsues @squatchknows @LWSmith15 @ADevotedYogi @JT375043170 @cappsie @AnaFuentesHomes @JSAHolmes @andylumm @ghoppe @temple_surly @JCDeardeuff @Craig12940777 @Crippsy1969 @barryjohnreid21 @bigmack600 @MaureenStroud @nancy41603 @lochard24 @NextGenRed @RTheatheist @johnnyutah66623 @BioVisionary @Bill20538001 @WhoCares011813 @livefre85257272 @wjack76995 @Truth_in_Number @UnclebuckJ @Kathmarval @markmcdougall13 @nyob7714 @BrowningNeelyn @KayVonPaul @Alex_on_A14 @WendyOrent @Will_holliday1 @NateWeymouth @FineAndBrennan This doesn’t “connect” them. Causality requires a control group. 50% of placebo recipients report an adverse event during the course of a trial. https://t.co/lbsrhMKt8n

Dec 22, 2021 · 4 likes · 1 share · 5,520 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@CovidInquirer @doritmi @stevenmosher @LiamKav @JestrBob @AndrewLazarus4 @Bruidhinn @tenebra99 @Wheres_My_Beef @DCGreenZone1 @fiski70 @betrollinyou @TonyBaduy @policing_uk @TakethatCt @anarchic_teapot @FrankDElia7 @provaxtexan @MdRisette @Mchael21592783M @melissa94307909 @AGoldsmithEsq @mcfunny @Suesue2point0 @ScienceyS @Kolyin @dwramzimdmph @indyymac @ncdave4life @lucialiljegren @_mamadeb @quigley_jesse @iBlatant @gobantwo2 @diederikdk @Tony__Heller @Kathmarval @MilanovNina @ghoppe @AndyMac84956921 @SpookyJay36 @BichonAtLaw @deNutrients @floraoddchild @CharaStone6 @chickaboy @Top_Muppetries @smyl2day @SkepticalMutant @AcademicShards Anaphylaxis is considered to be caused by the immediate preceding exposure. It always presents to healthcare so it's easier to measure. Other events have a background rate. If these events are rare, differences between groups can be hard to determine. /f ht

Dec 9, 2021 · 3 likes · 5,520 followers View post →
BlasphemousBanana
@BlasphemousBan1 · X

@Watchmn821 This is the first mass vaccination since the internet. When did you first hear of VAERS? Why do you know what that is? More people know about it, because antivaxxers don’t stop talking about it https://t.co/Zd9CqpIWWM

Dec 9, 2021 · 94 followers View post →
BlasphemousBanana
@BlasphemousBan1 · X

@sun0369 @GBNEWS @AmyNicks_ This is the first mass vaccination since the internet. When did you first hear of VAERS? Why do you know what that is? More people know about it, because antivaxxers don’t stop talking about it https://t.co/Zd9CqpIWWM

Dec 9, 2021 · 94 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@TalonXavier_ @foofdawg @JerrySp58490055 @Raven4212 @ToTheLifeboats @ktibus @The_Seeadler @Hugo58927423 @mmelgar09 @Not_Important_B @doritmi @keithlaw @SatvaBody @brian_abramson @calnbg @LeeKurtiss @tenebra99 @andyoakes If 50% of trial participants who receive a placebo experience adverse events, are you now going to claim it’s caused by the placebo? WHY do you think we use a control group? Randomize? https://t.co/lbsrhMKt8n

Dec 7, 2021 · 3 likes · 5,520 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@RDeckard_2049 @Golfergirl2018 @Pmaxwellfnp So you don’t understand the fundamentals of epidemiology research? Why do we use a control group? That’s correct, 50% of placebo recipients report an adverse event during a trial. https://t.co/lbsrhMKt8n

Dec 6, 2021 · 3 likes · 5,520 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@TalonXavier_ @keithlaw @doritmi @MarkAselstine @Raven4212 @Not_Important_B @ktibus @SatvaBody @brian_abramson @calnbg @foofdawg @ToTheLifeboats @LeeKurtiss @The_Seeadler @tenebra99 @andyoakes How did you determine any event was related to the vaccine? Fifty percent of placebo recipients experience an adverse event during trials. You do realize there are background rates? https://t.co/lbsrhMKt8n

Dec 5, 2021 · 3 likes · 5,520 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@melissa94307909 @ScienceyS @indyymac @ncdave4life @TakethatCt @lucialiljegren @stevenmosher @Mchael21592783M @DCGreenZone1 @AndrewLazarus4 @_mamadeb @provaxtexan @quigley_jesse @iBlatant @Suesue2point0 @doritmi @gobantwo2 @diederikdk @tenebra99 @LiamKav @Tony__Heller @TonyBaduy @Kathmarval @Kolyin @MilanovNina @ghoppe @AndyMac84956921 @mcfunny @AGoldsmithEsq @SpookyJay36 @MdRisette @BichonAtLaw @deNutrients @FrankDElia7 @floraoddchild @CharaStone6 @chickaboy @Top_Muppetries @smyl2day @SkepticalMutant @AcademicShards @ConsequentialBr @carlsmythe @policing_uk @MarkReady47 @kevin_kehres @villagerssn @cooljamm55 @AGTCnews @bitcoinbookshop Cite your claims. Which adverse event systems? Be specific. Why capture adverse events if the public isn’t interested? 50% of placebo recipients report an adverse event. It’s why we use a control group. https://t.co/lbsrhMKt8n

Nov 28, 2021 · 1 like · 5,520 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@Dizzyuk @talkRADIO @NHS100K @TVKev @DrHoenderkamp How did you prove they removed it? If fifty percent of placebo recipients report an adverse event, is it related to the placebo? You do realize the estimates for risk are not determined by yellow card or VAERS? There’s no control group. https://t.co/lbsrhMKt8n

Nov 18, 2021 · 1 like · 5,520 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@Dizzyuk @1ohreally @beverleyturner @andrew_croxford Approximately 50% of placebo recipients report an adverse event during trials. Are you going to speak out against placebos? Adverse events may occur and be unrelated to the intervention. It's the reason we use a control group. https://t.co/lbsrhMKt8n

Nov 18, 2021 · 4 likes · 5,520 followers View post →
MFPL
@MFPL6 · X

@Inoguci @RagDiabolik @AmanzioMartina Ma stai scherzando? Ci sono tantissimi esperimenti sull'effetto nocebo, documentati biologicamente. Perché non provi a falsificarli? Esiste anche una review sistematica che mostra che il nocebo non è dovuto alla fallacia post hoc ergo propter hoc. https://t.co/nIAN7Sr14t

Nov 18, 2021 · 62 followers View post →
Dr Anne Condon
@SkepticalMutant · X

RT @crabb_vicki: @coviemyman @DSrole @Alan777774 @volpiranyas @AndOrNorLyn @Tony__Heller @LiamKav @VolatileAmine @mcfunny @TakethatCt @MdRi…

Nov 13, 2021 · 1 share · 1,635 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@coviemyman @DSrole @Alan777774 @volpiranyas @AndOrNorLyn @Tony__Heller @LiamKav @VolatileAmine @mcfunny @TakethatCt @MdRisette @lotusctr @BatRock8 @Top_Muppetries @SendAliensToMe @AlvaroIM77 @estockbridge @Suesue2point0 @questauthority @provaxtexan @RobHeatherly1 @AGoldsmithEsq @docstardust @doritmi @Kolyin @Kathmarval @chickaboy @FrankDElia7 @foofdawg @OAPym @smyl2day @quigley_jesse @ConsequentialBr @_mamadeb @deNutrients @DCGreenZone1 @ghoppe @CharaStone6 @AndrewLazarus4 @SkepticalMutant @AcademicShards @TonyBaduy @carlsmythe @policing_uk @dnh214 @BichonAtLaw @MarkReady47 @tenebra99 @kevin_kehres @MilanovNina Fifty percent of placebo recipients report adverse events with ~10% requiring withdrawal from the trial. There are adverse effect related to vaccination. The vast majority are mild. How do you determine the events are related? https://t.co/lbsrhMKt8n

Nov 13, 2021 · 3 likes · 1 share · 5,520 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@KKP1111 @libertyGRoots @peterrowen_ You'll need to support your claims. ~50% of placebo recipients report an adverse event in trials, some result in the participant leaving the trial. This is why we use a comparison group. Events occur that are unrelated to an intervention. https://t.co/lbsrhMKt8n

Nov 9, 2021 · 5,520 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@Whitey900 @richienrg @sheridan_bhatt @DSrole @JRJHealey @dr_colemami @cappsie @hauxton @KStateTurk @sandycreekmill @daninphx @BlainEillimatta @HawkingsJulia @ale_battini @TakethatCt @NiklasT20 @groin_hammer @Alex_on_A14 @keigh_see @Chris_F_Carson @Allergic2Masks @keigh_seeToo @SwordFinger @LCS_Big_Mike @kevconrad2 @LaikaAndYuri @kmtildsley @Lisa41361016 @avogadr0avocado @moravec_tomas @HarveyWall15 @mcfunny @SimonGraf19 @Housekeep3r @AngelosPantone @Catnetsys3 @rapidgator99 @HouseOfGab @ine69206804 @KathySm59005579 @brbrofsvl @darnitcomics @TomahawkVPhD @20manDan @Greg44690 @Gen05761427 @ishitachhel @jacques_barzun @films_virus Despite its flaws and misuse, VAERS serves a purpose. It serves to detect potential safety (and efficacy trends) issues. ~50% of placebo recipients suffer an adverse event during a trial. https://t.co/lbsrhMKt8n

Nov 2, 2021 · 4 likes · 5,520 followers View post →
Dr Anne Condon
@SkepticalMutant · X

RT @crabb_vicki: @villagerssn @provaxtexan @LiamKav @ZaynJaffer @DCGreenZone1 @policing_uk @stevenmosher @_mamadeb @Kathmarval @vaxxinesRpo…

Oct 18, 2021 · 2 shares · 1,635 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@villagerssn @provaxtexan @LiamKav @ZaynJaffer @DCGreenZone1 @policing_uk @stevenmosher @_mamadeb @Kathmarval @vaxxinesRpoison @tenebra99 @Top_Muppetries @PPALtd @ncdave4life @TonyBaduy @doritmi @AGTCnews @EstesPga @MathewMoisture @richykirsh @SkepticalMutant @FillmoreWhite @DomIsa6 @chickaboy @RailFareWatch @TakethatCt @AcademicShards @mcfunny @llambchops @Tony__Heller @AJL037 @GeoffSchuler @RedSatoshi4 @AndrewLazarus4 @THC1001 @cooljamm55 @luigi_warren @realPitBullDog @Mchael21592783M @krebiozen @murdersquirrel @SeriousSkeptic @DanChesler @GenxlF @AmericanaMinds1 @juan_moment @RobinH00dThe2nd @itsnotallabout2 @Thedaphster39 @Lam37820433 50% of clinical trial participants report adverse events after receiving a placebo. Events happen. It’s the reason we randomize (to make groups comparable) and use a control group (to estimate background risk). https://t.co/lbsrhMKt8n

Oct 13, 2021 · 9 likes · 2 shares · 5,520 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@SassyGirlD1 @ghoppe @temple_surly @andylumm @Alex_on_A14 @JSAHolmes @Bebert701 @mcfunny @RTheatheist @Meribel123 @barryjohnreid21 @wjack76995 @SongFei2017 @BurgerLab12 @UnclebuckJ @BrowningNeelyn @WendyOrent @KayVonPaul @oshodhayansats1 @jamesgordon4th @ChrisJohnsonMD @SmashCarm @thatsnotmine125 @davidsirias1 @UKCryptoKing247 @pawley_robert @MaureenStroud @JosieJoBee @farrishimo @MdRisette @ginapro @nyob7714 @bat92799926 @TheMarCam @Tampa_Egret @fredwibblington @Kathmarval @GTabiadon @swedishchf @carlsmythe @Poopsie31 @hypnosexotica @VeritasMarcus @TakeThatCDC @BioVisionary @DEKKplans @DontMes70957787 50% of placebo recipients in RCTs report adverse events, these events result in ~10% withdrawing from the trials. There are background rates and temporality is necessary but not sufficient to infer causality. https://t.co/lbsrhMKt8n

Oct 13, 2021 · 2 likes · 5,520 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@drjohnm ~50% of placebo recipients report an adverse event. About 5% quit the trial. It’s the reason we use a control group. There’s a background rate to every event except anaphylaxis. https://t.co/lbsrhMKt8n

Oct 8, 2021 · 2 likes · 5,520 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@AgrkOne @DrMikeMendoza Adverse event are reported by 50% of participants receiving a placebo. Controls serve as estimates of background rates. Please cite the science literature. https://t.co/lbsrhMKt8n

Oct 6, 2021 · 2 likes · 5,520 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@Ender205 @Monstercoyliar @inewton31536845 @mcfunny @riderwbow @provaxtexan @IamTybalt79 @AndrewLazarus4 @SkepticalMutant @Tony__Heller @GeoffSchuler @GoSteelers2019 @MaureenStroud @Bosky83 @zeetubes @Fleur_Ru11 @melcake1000 @AkireTe @Kathmarval @AJL037 @SultaneAlexand1 @JimeeLiberty @michaelbranniga @WendyOrent @MsTrixter @TakethatCt @FactPhily @ItsScienceJim @T33879 @TonyBaduy @MichaelBuerger8 @CptMutant @StephenBevan15 @andylumm @OldIowaGirl @realPitBullDog @ActivistChick7 @RickLazzarini @krebiozen @Ryanleitch18 @Sallysheeple @AndrewBowdenSm1 @MrDarcy1815 @Shared_facts @LargeCoffee2Go @21WIRE @SeriousSkeptic @nomyhutch @zinlo22 @77777rep Did you know that ~ 50% of trial participants experience an adverse event? https://t.co/lbsrhMKt8n

Oct 1, 2021 · 2 likes · 5,520 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@MsTrixter @RobertHartley77 @richykirsh @mcfunny @deralteGaukler @tenebra99 @hughriminton @10NewsFirst @NSWAmbulance Do they have a special code for placebo adverse events? The prevalence of adverse events in placebo groups is ~ 50%. It’s why we use control groups. https://t.co/lbsrhN23ZV

Sep 22, 2021 · 1 like · 5,520 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@BlueLionBlog @drjohnm Why do we use a control group? Because AEs occur with placebos too. Everything has a background rate. Control groups provide estimates of background risk. The median prevalence of AEs in trial placebo groups was 49.1% (IQR 25.7–64.4%). /1 https://t.co/lbsrhMKt8n

Sep 11, 2021 · 5,520 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@patriot_doug @mcfunny @GeoConservative @BottomleyFiona @DawnTJ90 @DeoOmniaVincit @ronne_robert @Friendof_Darwin @fergy1999 @hauxton @LauraDekker1 @WendyOrent @k_b_lvi @MichaelYeadon3 @TonyBaduy @provaxtexan @carlsmythe @runningrabbit_1 @FrankDElia7 @AndrewLazarus4 @TakethatCt @JohnMarcmail @WhitePi11ed @krebiozen @Robin_Hagues @Tony__Heller @FormerAntivax @DK25769559 @BruceFo43322941 @RadioColor @BigBopp75348974 @MarioMoney23 @bayouskeeter @handmadekathy @Kathmarval @arcon_ryan @joltdude @swedishchf @littleLishka @EntrepreneurFg @_mamadeb @SkepticalMutant @MsTrixter @100Dianne @GeoffSchuler @1_TMF_ @ScepticalAussie @groin_hammer @marcus66508078 @doritmi “The median prevalence of AEs in trial placebo groups was 49.1% (IQR 25.7–64.4%). The median rate of dropouts due to AEs was 5% (IQR 2.28–8.4%).” https://t.co/lbsrhMKt8n

Sep 6, 2021 · 2 likes · 5,520 followers View post →
(((Dorit Reiss)))
@doritmi · X

RT @crabb_vicki: @dazg_11 @FrankDElia7 @krebiozen @RefusenikRed @doritmi @mcfunny @FormerAntivax @100Dianne @Kathmarval @TonyBaduy @1_TMF_…

Jul 16, 2021 · 2 shares · 15,059 followers View post →
Vicki Allen Crabb
@crabb_vicki · X

@dazg_11 @FrankDElia7 @krebiozen @RefusenikRed @doritmi @mcfunny @FormerAntivax @100Dianne @Kathmarval @TonyBaduy @1_TMF_ @ScepticalAussie @SkepticalMutant @runningrabbit_1 @groin_hammer @marcus66508078 @DeoOmniaVincit @littleLishka @handmadekathy @joltdude @AndrewLazarus4 @nia3in @swedishchf @LandmineLenny @Just4TheCause @GeneTherapy68 @hauxton @TakethatCt @WendyOrent @MsTrixter @provaxtexan @vinnumbskull @GeoffSchuler @PaulVCooper1 @Tawdge @LauraDekker1 @_mamadeb @emartinez78987 @bgspence @MAhealthforkids @pleasetellmeM @TinFoilAwards @Angel_13_Rising @7_DSSEVEN @JamesElijahMill @Charitable_Fury @PriestofBaal @Aly_Meek @jkellyca @jengleruk No. Every pharmaceutical/biological can elicit an adverse event, even placebos and saline. Why? Because most events have a background rate (headache, stomachs, etc) and these events may be unrelated to the intervention. https://t.co/lbsrhMKt8n

Jul 16, 2021 · 6 likes · 2 shares · 5,520 followers View post →
Jeremy Howick
@JeremyHowick · X

2/Our background research shows - How potential treatment harms are shared in #PatientInformation Leaflets varies...sometimes benefits not even mentioned: https://t.co/9PtWiJ9Qo5 - The way information about harms is shared can cause harm (nocebo effects): https://t.co/nadXfVUYGn

May 20, 2021 · 1 like · 4,764 followers View post →
Shaun Treweek
@shauntreweek · X

RT @MRCNIHRTMRP: Does the way in which we tell people about potential side effects in drug trials harm them? A rapid overview of systematic…

Nov 2, 2020 · 3 shares · 3,274 followers View post →
Nottingham Eczema
@eczemasupport · X

RT @MRCNIHRTMRP: Does the way in which we tell people about potential side effects in drug trials harm them? A rapid overview of systematic…

Nov 2, 2020 · 3 shares · 6,897 followers View post →
Jeremy Howick
@JeremyHowick · X

RT @MRCNIHRTMRP: Does the way in which we tell people about potential side effects in drug trials harm them? A rapid overview of systematic…

Nov 2, 2020 · 3 shares · 4,764 followers View post →
MRC-NIHR Trials Methodology Research Partnership
@MRCNIHRTMRP · X

Does the way in which we tell people about potential side effects in drug trials harm them? A rapid overview of systematic reviews. @jeremyhowick @nigelkirby97 @kerryhood #TrialConductResearch https://t.co/JMrUpxxFjP

Nov 2, 2020 · 3 likes · 3 shares · 2,653 followers View post →
Сатоші Окано
@okano00001 · X

RT @okanoshinryoin: マンガでわかるプラセボ効果11 プラセボ効果の邪悪な双子!? 医道の日本2020年2月号より https://t.co/H3zkay6P0B

Feb 12, 2020 · 1 share · 2,292 followers View post →
おかの針療院
@okanohari · X

マンガでわかるプラセボ効果11 プラセボ効果の邪悪な双子!? 医道の日本2020年2月号より https://t.co/H3zkay6P0B

Feb 12, 2020 · 1 like · 1 share · 60 followers View post →
Jeremy Howick
@JeremyHowick · X

50% of placebo treated patients in trials report an adverse event; 5% drop out due to intervention 'intolerance'. Some of that is misattribution, some is genuine nocebo: https://t.co/GY4BYVx3Nn https://t.co/1jCTIqNrAt

Oct 24, 2019 · 4,764 followers View post →
7JK
@7JK11 · X

Rapid overview of systematic reviews of nocebo effects reported by patients taking placebos in clinical trials https://t.co/qgGEMolY7D #trialsjournal 多言に惑わされるのが1番の毒って事かの(∵)

May 26, 2019 · 65 followers View post →
J.B. Negrón
@negronjb · X

Rapid overview of systematic reviews of nocebo effects reported by patients taking placebos in clinical trials "The median prevalence of adverse events in trial placebo groups was 49.1% (IQR 25.7–64.4%)" Full-text: https://t.co/ZcVohJBbkG #trialsjournal

May 20, 2019 · 1,445 followers View post →
もにょん
@Nyoro_mazymaze · X

RT @ymori117: 元論文はこちら: Rapid overview of systematic reviews of nocebo effects reported by patients taking placebos in clinical trials. - Pu…

Jan 1, 2019 · 8 shares · 360 followers View post →
早房一平
@hayabusa_ippei · X

RT @ymori117: 元論文はこちら: Rapid overview of systematic reviews of nocebo effects reported by patients taking placebos in clinical trials. - Pu…

Jan 1, 2019 · 8 shares · 1,383 followers View post →
CPT 1626 | PDF | Placebo | Randomized Controlled Trial
News

(2018).10.1186/s13063-018-3042-4 (30) Stroes, E.S. et al. Statin-associated muscle symptoms: Impact on statin therapy-european atherosclerosis society ...

Jan 6, 2026 View →
Plasebo Etkisi Nedir? Deneylerde Plasebo Nasıl Kullanılır? - Evrim ...
Blogs

... 10.1186/1741-7015-8-15. | Arşiv Bağlantısı; ^ K. Meissner, et al ... s13063-018-3042-4. | Arşiv Bağlantısı; ^ J. Grange. (2008). Dangers ...

Nov 7, 2022 View →
糖丸使我胃痛:反安慰剂效应与消极的自我暗示| Trials—论文—科学网
News

数字识别码:10.1186/s13063-018-3042-4. 原文链接:https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-018-3042-4?utm_source ...

Apr 9, 2019 View →
Harmful placebos
News

DOI: 10.1186/s13063-018-3042-4. Journal information: The Lancet. Provided by University of Oxford. + Explore further. Harms reporting in trials ...

Dec 11, 2018 View →