PubHawk
February 2019 PMID 30557670

Assessing the in vivo data on low/no-calorie sweeteners and the gut microbiota.

Alexandra R Lobach, Ashley Roberts, Ian R Rowland

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Mentions

71
Peak: 14 in Jul 2019
across 5 sources since Jan 2019

Extended reach

543,184
potential audience

Total likes

497

Video views

4,124

Mentions per month

Jan 2019 – Jun 2024

Where it's discussed

  • X / Twitter50 posts
  • News10 articles
  • Blogs5 articles
  • YouTube3 videos
  • Facebook3 posts

AI synopsis

What people are saying

The group generally agrees that existing evidence indicates LNCS are safe at approved levels, citing studies like Lobach et al. and emphasizing that high-dose rodent research lacks relevance to humans. The tone varies from supportive to critically questioning, with words like 'evidence', 'limitations', and 'effects' guiding the moderate engagement level.

AgreementModerate agreement

Most discussions indicate support for the review’s conclusion that LNCS do not have proven adverse effects on human health, though some entertain caution and ongoing debate.

InterestModerate interest

Posts reflect modest curiosity about the research, with some expressing skepticism or highlighting the nuances, rather than high enthusiasm.

EngagementModerate engagement

Participants reference specific studies, question methodologies, and discuss implications, showing moderate in-depth analysis and critical thinking.

ImpactModerate impact

The overall tone suggests the discussion may influence perceptions about LNCS safety but stops short of claiming immediate widespread change.

Abstract in brief

  • The review examines whether low-calorie sweeteners (LNCS) like aspartame, saccharin, and sucralose impact the gut microbiota, especially after a 2014 study linked them to increased glucose intolerance.
  • Most rodent studies showing microbiome changes involved extremely high doses of saccharin, which are not relevant to typical human consumption, and these studies did not show actual harm to human health.
  • Overall, the evidence indicates that diet changes other than LNCS are the main factors affecting gut microbiota, and major health authorities agree that LNCS are safe at currently approved levels.]
Read the full abstract

Top posts

Most liked on X and Bluesky
Fateme Moradi
@moradidiet · X

که این دو تا مطالعه روی این موضوع کار کردن. حقیقت اینه که مطالعات نشون می‌دن NNS اثر بدی روی میکروب‌های روده ندارن. اکثر NNSها در روده کوچک جذب میشن و به روده بزرگ (محل زندگی این باکتری ها) نمی‌رسن. 8 از 16 https://t.co/0v6wlgHzew https://t.co/OTKh0LdLHp

Sep 5, 2022 · 199 likes · 1 share · 4,238 followers View post →
Layne Norton, PhD
@BioLayne · X

Evidence for this: https://t.co/zCgCiMiOt7 https://t.co/Qd4RrRJfFU https://t.co/Qk8OkpTppn Data>Your feelings

Jun 30, 2021 · 98 likes · 7 shares · 223,419 followers View post →
Elisabeth Bik
@MicrobiomDigest · X

Oh, this is an interesting Letter to the Editor: Revisited: Assessing the in vivo data on low/no-calorie sweeteners and the gut microbiota Susan S. Schiffman & H. Troy Nagle https://t.co/YgKXDyTvQu https://t.co/aA4fBfwvCS

Jul 28, 2019 · 29 likes · 5 shares · 143,459 followers View post →
바이오매니아
@microviolist · X

아무튼 원논문이 나온 후 10년 동안 모든 인공감미료가 장내미생물에 영향을 준다는 논문들과 반대의 논문들이 나오고 혼돈의 시간이 흘러가다가 2019년에 장내미생물 균총 측면에서 2008년 원논문에 대한 비판이 제기됩니다. 결론은 현재 수준에서 안전하다는 것. https://t.co/15dvw4lYX0

Feb 14, 2021 · 23 likes · 25 shares · 5,471 followers View post →
Dr. David L. Katz
@DrDavidKatz · X

Revisited: Assessing the in vivo data on low/no-calorie sweeteners and... https://t.co/8ElmscDYdc - perhaps advantageous over added sugar, but suspect. A whole-foods, plant-predominant diet would minimize added sugar AND avoid LNCS

Aug 7, 2019 · 7 likes · 1 share · 43,046 followers View post →
Sam | The Pharma wizard
@sam_scandar · X

Lobach AR, Roberts A, Rowland IR. Assessing the in vivo data on low/no-calorie sweeteners and the gut microbiota. Food Chem Toxicol. 2019 Feb;124:385-399. doi: 10.1016/j.fct.2018.12.005. Epub 2018 Dec 14. PMID: 30557670.

Jan 1, 2022 · 4 likes · 1,311 followers View post →

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캰 :
@iluose · X

RT @microviolist: 아무튼 원논문이 나온 후 10년 동안 모든 인공감미료가 장내미생물에 영향을 준다는 논문들과 반대의 논문들이 나오고 혼돈의 시간이 흘러가다가 2019년에 장내미생물 균총 측면에서 2008년 원논문에 대한 비판이 제기됩니…

Jun 7, 2023 · 25 shares · 68 followers View post →
레이니스
@noonday_demon · X

RT @microviolist: 아무튼 원논문이 나온 후 10년 동안 모든 인공감미료가 장내미생물에 영향을 준다는 논문들과 반대의 논문들이 나오고 혼돈의 시간이 흘러가다가 2019년에 장내미생물 균총 측면에서 2008년 원논문에 대한 비판이 제기됩니…

Jun 6, 2023 · 25 shares · 169 followers View post →
ADEL ALTURKI
@ALTURKI_USA · X

RT @BioLayne: Evidence for this: https://t.co/zCgCiMiOt7 https://t.co/Qd4RrRJfFU https://t.co/Qk8OkpTppn Data>Your feelings

Jan 9, 2023 · 7 shares · 59 followers View post →
Denny Mishler
@dennymishler · X

@Dan900H @EssexPR @trussliz Not that you care about what the science says, but we’re talking decades of human outcome data. And you think ALL of them are in on a big conspiracy? https://t.co/y3RhWq5lkB https://t.co/pUW1AzVbfY https://t.co/3gHk2tuhSg

Sep 15, 2022 · 1,066 followers View post →
Denny Mishler
@dennymishler · X

@DogNeumann @JBONAMASSA Except the data do not show that. We have a ton of studies going back decades. There’s no good reason to suspect anything. Evidence: https://t.co/y3RhWq5lkB https://t.co/pUW1AzVbfY https://t.co/3gHk2tuhSg

Sep 13, 2022 · 1,066 followers View post →
pour
@ghasempo · X

RT @moradidiet: که این دو تا مطالعه روی این موضوع کار کردن. حقیقت اینه که مطالعات نشون می‌دن NNS اثر بدی روی میکروب‌های روده ندارن. اکثر NN…

Sep 6, 2022 · 1 share · 388 followers View post →
Fateme Moradi
@moradidiet · X

که این دو تا مطالعه روی این موضوع کار کردن. حقیقت اینه که مطالعات نشون می‌دن NNS اثر بدی روی میکروب‌های روده ندارن. اکثر NNSها در روده کوچک جذب میشن و به روده بزرگ (محل زندگی این باکتری ها) نمی‌رسن. 8 از 16 https://t.co/0v6wlgHzew https://t.co/OTKh0LdLHp

Sep 5, 2022 · 199 likes · 1 share · 4,238 followers View post →
Sam | The Pharma wizard
@sam_scandar · X

Lobach AR, Roberts A, Rowland IR. Assessing the in vivo data on low/no-calorie sweeteners and the gut microbiota. Food Chem Toxicol. 2019 Feb;124:385-399. doi: 10.1016/j.fct.2018.12.005. Epub 2018 Dec 14. PMID: 30557670.

Jan 1, 2022 · 4 likes · 1,311 followers View post →
Marcus Wolford
@mvmntcoach · X

"This and other studies suggesting an effect of LNCS (Low/no-calorie sweeteners) on the gut microbiota were found to show no evidence of an actual adverse effect on human health." https://t.co/reJFdyqfh2

Aug 31, 2021 · 1 like · 2,435 followers View post →
Alec Tramblay
@ATramblay · X

@Randomtweet40 @RatioFood Lmao the classic hasty generalization fallacy. Science doesn’t care about you uneducated feelings. https://t.co/IIEnz5l7bw https://t.co/lAcWIg3Lg2 https://t.co/xS3G4mvqqT

Aug 8, 2021 · 137 followers View post →
batuhanteomete
@Vladmir_123 · X

RT @BioLayne: Evidence for this: https://t.co/zCgCiMiOt7 https://t.co/Qd4RrRJfFU https://t.co/Qk8OkpTppn Data>Your feelings

Jul 1, 2021 · 7 shares · 25 followers View post →
MK
@muralijnu1 · X

RT @BioLayne: Evidence for this: https://t.co/zCgCiMiOt7 https://t.co/Qd4RrRJfFU https://t.co/Qk8OkpTppn Data>Your feelings

Jun 30, 2021 · 7 shares · 170 followers View post →
Raul
@RaulM06 · X

RT @BioLayne: Evidence for this: https://t.co/zCgCiMiOt7 https://t.co/Qd4RrRJfFU https://t.co/Qk8OkpTppn Data>Your feelings

Jun 30, 2021 · 7 shares · 856 followers View post →
Robinhood Pandey
@rushhhourr · X

RT @BioLayne: Evidence for this: https://t.co/zCgCiMiOt7 https://t.co/Qd4RrRJfFU https://t.co/Qk8OkpTppn Data>Your feelings

Jun 30, 2021 · 7 shares · 335 followers View post →
Bhopender Thakur
@TheBhupiThakur · X

RT @BioLayne: Evidence for this: https://t.co/zCgCiMiOt7 https://t.co/Qd4RrRJfFU https://t.co/Qk8OkpTppn Data>Your feelings

Jun 30, 2021 · 7 shares · 1,366 followers View post →
Layne Norton, PhD
@BioLayne · X

Evidence for this: https://t.co/zCgCiMiOt7 https://t.co/Qd4RrRJfFU https://t.co/Qk8OkpTppn Data>Your feelings

Jun 30, 2021 · 98 likes · 7 shares · 223,419 followers View post →
Ismael Galancho
@IsmaelGalancho · X

@ZsoltNagy7 @kevinnbass Sure they alter the microbiome? https://t.co/u6p1ysRf9C

Apr 23, 2021 · 40,804 followers View post →
demerol
@_endofnight · X

RT @MOFoodSci: 아무튼 원논문이 나온 후 10년 동안 모든 인공감미료가 장내미생물에 영향을 준다는 논문들과 반대의 논문들이 나오고 혼돈의 시간이 흘러가다가 2019년에 장내미생물 균총 측면에서 2008년 원논문에 대한 비판이 제기됩니다.…

Feb 15, 2021 · 25 shares · 20 followers View post →
btlnmtx
@btlnmtx · X

RT @MOFoodSci: 아무튼 원논문이 나온 후 10년 동안 모든 인공감미료가 장내미생물에 영향을 준다는 논문들과 반대의 논문들이 나오고 혼돈의 시간이 흘러가다가 2019년에 장내미생물 균총 측면에서 2008년 원논문에 대한 비판이 제기됩니다.…

Feb 14, 2021 · 25 shares · 233 followers View post →
고추장
@kkochu · X

RT @MOFoodSci: 아무튼 원논문이 나온 후 10년 동안 모든 인공감미료가 장내미생물에 영향을 준다는 논문들과 반대의 논문들이 나오고 혼돈의 시간이 흘러가다가 2019년에 장내미생물 균총 측면에서 2008년 원논문에 대한 비판이 제기됩니다.…

Feb 14, 2021 · 25 shares · 1,261 followers View post →
이진서
@jinnys0 · X

RT @MOFoodSci: 아무튼 원논문이 나온 후 10년 동안 모든 인공감미료가 장내미생물에 영향을 준다는 논문들과 반대의 논문들이 나오고 혼돈의 시간이 흘러가다가 2019년에 장내미생물 균총 측면에서 2008년 원논문에 대한 비판이 제기됩니다.…

Feb 14, 2021 · 25 shares · 792 followers View post →
로예(Roye) 叡蓮
@redlotusyj · X

RT @MOFoodSci: 아무튼 원논문이 나온 후 10년 동안 모든 인공감미료가 장내미생물에 영향을 준다는 논문들과 반대의 논문들이 나오고 혼돈의 시간이 흘러가다가 2019년에 장내미생물 균총 측면에서 2008년 원논문에 대한 비판이 제기됩니다.…

Feb 14, 2021 · 25 shares · 730 followers View post →
하진
@1MU98nk8CBKZKU7 · X

RT @MOFoodSci: 아무튼 원논문이 나온 후 10년 동안 모든 인공감미료가 장내미생물에 영향을 준다는 논문들과 반대의 논문들이 나오고 혼돈의 시간이 흘러가다가 2019년에 장내미생물 균총 측면에서 2008년 원논문에 대한 비판이 제기됩니다.…

Feb 14, 2021 · 25 shares · 17 followers View post →
세번째 달
@newlife_nd · X

RT @MOFoodSci: 아무튼 원논문이 나온 후 10년 동안 모든 인공감미료가 장내미생물에 영향을 준다는 논문들과 반대의 논문들이 나오고 혼돈의 시간이 흘러가다가 2019년에 장내미생물 균총 측면에서 2008년 원논문에 대한 비판이 제기됩니다.…

Feb 14, 2021 · 25 shares · 490 followers View post →
흰곰탱이
@GreedyWhiteBear · X

RT @MOFoodSci: 아무튼 원논문이 나온 후 10년 동안 모든 인공감미료가 장내미생물에 영향을 준다는 논문들과 반대의 논문들이 나오고 혼돈의 시간이 흘러가다가 2019년에 장내미생물 균총 측면에서 2008년 원논문에 대한 비판이 제기됩니다.…

Feb 14, 2021 · 25 shares · 2,039 followers View post →
Nekizlab
@nekizlab · X

RT @MOFoodSci: 아무튼 원논문이 나온 후 10년 동안 모든 인공감미료가 장내미생물에 영향을 준다는 논문들과 반대의 논문들이 나오고 혼돈의 시간이 흘러가다가 2019년에 장내미생물 균총 측면에서 2008년 원논문에 대한 비판이 제기됩니다.…

Feb 14, 2021 · 25 shares · 2,444 followers View post →
THE PEACE21
@maerdymteg · X

RT @MOFoodSci: 아무튼 원논문이 나온 후 10년 동안 모든 인공감미료가 장내미생물에 영향을 준다는 논문들과 반대의 논문들이 나오고 혼돈의 시간이 흘러가다가 2019년에 장내미생물 균총 측면에서 2008년 원논문에 대한 비판이 제기됩니다.…

Feb 14, 2021 · 25 shares · 561 followers View post →
내 세금이여
@suhhee2 · X

RT @MOFoodSci: 아무튼 원논문이 나온 후 10년 동안 모든 인공감미료가 장내미생물에 영향을 준다는 논문들과 반대의 논문들이 나오고 혼돈의 시간이 흘러가다가 2019년에 장내미생물 균총 측면에서 2008년 원논문에 대한 비판이 제기됩니다.…

Feb 14, 2021 · 25 shares · 2,006 followers View post →
바이오매니아
@microviolist · X

아무튼 원논문이 나온 후 10년 동안 모든 인공감미료가 장내미생물에 영향을 준다는 논문들과 반대의 논문들이 나오고 혼돈의 시간이 흘러가다가 2019년에 장내미생물 균총 측면에서 2008년 원논문에 대한 비판이 제기됩니다. 결론은 현재 수준에서 안전하다는 것. https://t.co/15dvw4lYX0

Feb 14, 2021 · 23 likes · 25 shares · 5,471 followers View post →
Ismael Galancho
@IsmaelGalancho · X

@jordifit_com @ElComidista No es que lo diga yo, es lo que dice la ciencia. Es cierto q es un tema donde hay datos contrarios y por eso es clave interpretar bien los estudios. Algunos presentan serias limitaciones como el de Juaez et al 2014 respecto a microbiota. Ya lo dijo Lobach https://t.co/u6p1ysRf9C

Oct 16, 2020 · 40,804 followers View post →
Jae Rosario
@thoughtsbyjae_ · X

@MarieCorcoran13 https://t.co/1KBRLns1Oh https://t.co/LPlPvdnftq https://t.co/iH4ZEcOL1x https://t.co/omqnYXWDnz https://t.co/NKDsTznyq3 https://t.co/NNz8b101SI]

Aug 31, 2020 · 2,098 followers View post →
Asihandi
@Asihandi1 · X

@AlexGayo @DrRamonDeCangas Este es el trabajo que yo recordaba https://t.co/XQkXYt0E9p pero veo que ha sido recientemente cuestionado por https://t.co/biTiVI6Uos. No conozco el campo e igual no sé discriminar entre buenos y malos, pero sí que hay estudios reportando efectos adversos.

May 12, 2020 · 29 followers View post →
SusieB
@flavorscientist · X

Just have sugar. Forget the fake stuff and avoid the belly aches.Revisited: Assessing the in vivo data on low/no-calorie sweeteners and... https://t.co/KAiH3nkgtM

Feb 17, 2020 · 1 like · 944 followers View post →
plantbasedntgr
@plantbasedntgr · X

RT @DrDavidKatz: Revisited: Assessing the in vivo data on low/no-calorie sweeteners and... https://t.co/8ElmscDYdc - perhaps advantageous o…

Aug 8, 2019 · 1 share · 29 followers View post →
Dr. David L. Katz
@DrDavidKatz · X

Revisited: Assessing the in vivo data on low/no-calorie sweeteners and... https://t.co/8ElmscDYdc - perhaps advantageous over added sugar, but suspect. A whole-foods, plant-predominant diet would minimize added sugar AND avoid LNCS

Aug 7, 2019 · 7 likes · 1 share · 43,046 followers View post →
HealthyBuilds
@HealthyBuilds · X

Revisited: Assessing the in vivo data on low/no-calorie sweeteners and the gut microbiota https://t.co/7j08UKYKkW

Jul 30, 2019 · 199 followers View post →
Sanders Inc.
@SandersFilters · X

Revisited: Assessing the in vivo data on low/no-calorie sweeteners and the gut microbiota https://t.co/QluujzpPfe

Jul 30, 2019 · 173 followers View post →
HealthyBuilds West Palm
@NanoSafe1 · X

Revisited: Assessing the in vivo data on low/no-calorie sweeteners and the gut microbiota https://t.co/JD4K2WmYjF

Jul 30, 2019 · 192 followers View post →
Pere Joan Sala
@Fradbius · X

Revisited: Assessing the in vivo data on low/no-calorie sweeteners and... https://t.co/EWooooweLt

Jul 29, 2019 · 249 followers View post →
Haruo Suzuki
@copypasteusa · X

RT @MicrobiomDigest: Oh, this is an interesting Letter to the Editor: Revisited: Assessing the in vivo data on low/no-calorie sweeteners a…

Jul 29, 2019 · 5 shares · 1,305 followers View post →
Marjolaine Viret, PhD
@MarjolaineViret · X

RT @MicrobiomDigest: Oh, this is an interesting Letter to the Editor: Revisited: Assessing the in vivo data on low/no-calorie sweeteners a…

Jul 29, 2019 · 5 shares · 1,116 followers View post →
Shreya Ghosh
@shrez07 · X

RT @MicrobiomDigest: Oh, this is an interesting Letter to the Editor: Revisited: Assessing the in vivo data on low/no-calorie sweeteners a…

Jul 29, 2019 · 5 shares · 144 followers View post →
Dataemia
@Dataemia · X

Revisited: Assessing the in vivo data on low/no-calorie sweeteners and the gut microbiota. - https://t.co/n4ehUaHVgo https://t.co/Q8MyZBcx0G

Jul 29, 2019 · 967 followers View post →
Victoria Doudenkova
@Doudenkova · X

RT @MicrobiomDigest: Oh, this is an interesting Letter to the Editor: Revisited: Assessing the in vivo data on low/no-calorie sweeteners a…

Jul 28, 2019 · 5 shares · 136 followers View post →
Tierra
@EnAlgunaTierra · X

RT @MicrobiomDigest: Oh, this is an interesting Letter to the Editor: Revisited: Assessing the in vivo data on low/no-calorie sweeteners a…

Jul 28, 2019 · 5 shares · 819 followers View post →
Elisabeth Bik
@MicrobiomDigest · X

Oh, this is an interesting Letter to the Editor: Revisited: Assessing the in vivo data on low/no-calorie sweeteners and the gut microbiota Susan S. Schiffman & H. Troy Nagle https://t.co/YgKXDyTvQu https://t.co/aA4fBfwvCS

Jul 28, 2019 · 29 likes · 5 shares · 143,459 followers View post →
HostMicrobiomePapers
@HostMicroPapers · X

Revisited: Assessing the in vivo data on low/no-calorie sweeteners and the gut microbiota. https://t.co/Lpdd0dk3CZ

Jul 28, 2019 · 190 followers View post →
Symbiosis papers
@Symbiosispapers · X

Revisited: Assessing the in vivo data on low/no-calorie sweeteners and the gut microbiota. https://t.co/d3x2l2oxo0

Jul 28, 2019 · 1,113 followers View post →
Microbiome Articles
@microbe_article · X

Revisited: assessing the in vivo data on low/no-calorie sweeteners and th... - Schiffman SS et al. - https://t.co/i78Ye5hG38 #microbiome

Jul 28, 2019 · 7,153 followers View post →
Anna Wittekind
@AnnaWittekind · X

Assessing the in vivo data on low/no-calorie sweeteners and the gut microbiota - ScienceDirect https://t.co/d9PHTL4GCc

Jan 16, 2019 · 54 followers View post →