Front Physiol December 2018 PMID 30564133

Chlorophyllin Modulates Gut Microbiota and Inhibits Intestinal Inflammation to Ameliorate Hepatic Fibrosis in Mice.

Han Zheng, Yang You, Meiyun Hua, Pengfei Wu, Yu Liu, Zishuo Chen, Li Zhang, Haoche Wei, Yan Li, Mei Luo, Yilan Zeng, Yong Liu, Dong-Xia Luo, Jie Zhang, Min Feng

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Mentions

7
Peak: 2 in Mar 2022
across 3 sources since Mar 2021

Extended reach

142,900
potential audience

Total likes

823

Video views

121,422

Mentions per month

Mar 2021 – Aug 2025

Where it's discussed

  • News3 articles
  • X / Twitter2 posts
  • YouTube2 videos

AI synopsis

What people are saying

The discussions reflect a cautious curiosity about the health claims related to chlorophyllin, with comments like questioning whether drinking liquid chlorophyll is scientifically supported. The tone varies from skeptical to mildly interested, influenced by social discussions and trending health topics, but without strong consensus or profound impact on perceptions.

AgreementNeither agree nor disagree

The discussions display a neutral stance, with some recognition of the study but little direct support or disagreement.

InterestModerate interest

There is mild curiosity surrounding the research, especially in relation to health trends like drinking liquid chlorophyll, but overall interest remains moderate.

EngagementModerate engagement

The posts show some engagement through critical commentary and curiosity, but lack deep analysis or extensive discussion.

ImpactNeutral impact

The conversations seem to have limited influence on broader health perceptions, reflecting cautious interest rather than large-scale impact.

Abstract in brief

  • This study found that chlorophyllin, a compound derived from green pigment, can reduce liver fibrosis in mice by decreasing inflammation in the gut and liver, and by balancing gut microbiota, specifically decreasing Firmicutes and increasing Bacteroidetes.
  • The research involved inducing liver fibrosis in mice using carbon tetrachloride and then treating them with chlorophyllin in drinking water, which led to improved survival, healthier liver tissue, and reduced inflammatory factors.
  • The mechanisms behind these effects include chlorophyllin's ability to inhibit the NF-kB pathway in intestinal cells, which helps reduce inflammation, suggesting that chlorophyllin could be useful in managing liver fibrosis through its influence on gut health.]

Top posts

Most liked on X and Bluesky
GoodRx
@GoodRx · X

A recent trend featured influencers drinking liquid chlorophyll and claiming it has health benefits. We separate fact from fiction and let you know if you should try it. https://t.co/LzneJWLZWW

Mar 22, 2022 · 13,395 followers View post →
Ashburn Connect
@ashburn_connect · X

Chlorophyllin Modulates Gut Microbiota and Inhibits Intestinal Inflammation to Ameliorate Hepatic Fibrosis in Mice https://t.co/SqnrAEOupW

Mar 28, 2021 · 8,053 followers View post →

All mentions

GoodRx
@GoodRx · X

A recent trend featured influencers drinking liquid chlorophyll and claiming it has health benefits. We separate fact from fiction and let you know if you should try it. https://t.co/LzneJWLZWW

Mar 22, 2022 · 13,395 followers View post →
Ashburn Connect
@ashburn_connect · X

Chlorophyllin Modulates Gut Microbiota and Inhibits Intestinal Inflammation to Ameliorate Hepatic Fibrosis in Mice https://t.co/SqnrAEOupW

Mar 28, 2021 · 8,053 followers View post →
Fnut 10 1089909 | PDF | Cirrhosis | Microbiota
News

10.3389/fphar.2021.693048 Front Physiol. (2018) 9:1671. doi: 10.3389/fphys.2018.01671 33. Li, H, Wang, Q, Chen, P, Zhou, C, Zhang, X, and Chen, L ...

Dec 13, 2025 View →
Chlorophyll water: Benefits, risks, and more
News

... 10.3389/fphys.2018.01671/full. Share this article. Medically reviewed by Jerlyn Jones, MS MPA RDN LD CLT — Written by Charlotte Lillis on ...

Aug 8, 2025 View →
Chlorophyll for IBS: Safety, effectiveness, and more
News

https://www.frontiersin.org/articles/10.3389/fphys.2018.01671/full. Share this article. Medically reviewed by Cynthia Taylor Chavoustie, MPAS ...

May 23, 2022 View →