Statin Safety and Associated Adverse Events: A Scientific Statement From the American Heart Association.

GP

Gil Carvalho MD PhD

@NutritionMadeS3 · X

1 in 4 Americans over 40yo is on a statin (!!!)

GP

Gil Carvalho MD PhD

@NutritionMadeS3 · X

'Most children in studies evaluating statins had heterozygous FH and were generally otherwise healthy, although of course, LDL-C levels were very high and lifetime risk of CVD was markedly increased' Dyslipidemia *IS* sufficient https://t.co/CTwyPf9etx

DM

Dr. Ilin Gilberto de la Torre M.

@IlindelatorreMD · X

Seguridad de la estatinas y eventos adversos asociados: una declaración científica de la American Heart Association https://t.co/VbwfUhZbj9

TD

Thomas Dayspring

@Drlipid · X

Statins and Diabetes: How Big Is the Risk? https://t.co/NmRUOBbkta Also see https://t.co/PZw5enGm17 https://t.co/kmKCsWBdN6

Y循

Yoichiro.S@循環器内科医

@cardio_dr_ys · X

【ACS後の脂質管理番外編　スタチンは安全？】 横紋筋融解症 <0.1%　筋症状<1% 重篤な肝障害<0.001% 脳出血発生に関連がある可能性 DMリスク因子ありではDM発生のHRは1.1−1.2 総じて低リスク、中止で改善するものが多い。 CV risk患者では投与の利点が上回ることが多い https://t.co/pSiZrgVMmZ

دا

د. ثامر العيسى

@thameralessa · X

Statin Safety and Associated Adverse Events: A Scientific Statement From the American Heart Association Helpful information for the clinicians to overcome the fear of statins adverse effects in the public and the misinformations in the social media. https://t.co/AkMtbrV1VM

HE

huseyinarslan.eth

@huseyinarslan89 · X

@drozcanyucel Söyleyebiliriz. 1 yeni dm hastasına karşılık 5 majör kardiyovasküler olay engelliyor statinler. https://t.co/TWZmXnmkYB

RI

#RaviVisvesvarayaSharadaPrasad #Telecom #InfoTech

@rvp · X

RT @BradStanfieldMD: References (1/2): https://t.co/GuzfqIwvjv https://t.co/IJICqHcWVm https://t.co/5PNMrBoM7O https://t.co/mGeG6qlx6I http…

IL

Isabel Zaldívar Laguía

@isabelzl · X

Statin Safety and Associated Adverse Events: A Scientific Statement From the American Heart Association | Arteriosclerosis, Thrombosis, and Vascular Biology https://t.co/LPko67FWTa

AD

Aces & Dueces

@AcesAndDueces · X

@AdamMeakins @JeffreyPengMD Need to look at RCTs for that or studies with much better adjustment models. So far those studies haven't shown any harm AFAIK. See the section on tendonitis in this review: https://t.co/2uVL89cQGy

DS

Dr Brad Stanfield

@BradStanfieldMD · X

References (1/2): https://t.co/GuzfqIwvjv https://t.co/IJICqHcWVm https://t.co/5PNMrBoM7O https://t.co/mGeG6qlx6I https://t.co/gPZgpzvEDO https://t.co/txJE3q2lEF https://t.co/OEuN5Nss3T https://t.co/0IR10iVfMQ

JM

Jussi Mustonen

@JusiMD · X

@medmyths https://t.co/Fh29p4H5yJ about non-muscle stuff

JM

Jussi Mustonen

@JusiMD · X

@DanClintonRN @BuhlerLaurent @GuyattGH 5. The decision to (dis)continue was related to the primary objective, not liver stuff 6. Sidetrack, but what ‘liver problems’ and where is P = 0.08 from? 7. Fortunately there’s other data on liver AEs, so don’t need to rely on JUPITER alone https://t.co/Fh29p4H5yJ

夢心

夢@心電図

@hSMpv375PTfWoMb · X

RT @cardio_dr_ys: 【ACS後の脂質管理番外編　スタチンは安全？】 横紋筋融解症 <0.1%　筋症状<1% 重篤な肝障害<0.001% 脳出血発生に関連がある可能性 DMリスク因子ありではDM発生のHRは1.1−1.2 総じて低リスク、中止で改善するものが多…

D

Das

@ssdas29 · X

@winner_nkem @winfinancial @AmyDee1001 @ww_us bad luck, liver failure? and check out these https://t.co/Q2VqMOsjsN Statin Safety and Associated Adverse Events: A Scientific Statement From the American Heart Association

K

kajimaorisama

@kajimaorisama · X

RT @cardio_dr_ys: 【ACS後の脂質管理番外編　スタチンは安全？】 横紋筋融解症 <0.1%　筋症状<1% 重篤な肝障害<0.001% 脳出血発生に関連がある可能性 DMリスク因子ありではDM発生のHRは1.1−1.2 総じて低リスク、中止で改善するものが多…

Y循

Yoichiro.S@循環器内科医

@cardio_dr_ys · X

【ACS後の脂質管理番外編　スタチンは安全？】 横紋筋融解症 <0.1%　筋症状<1% 重篤な肝障害<0.001% 脳出血発生に関連がある可能性 DMリスク因子ありではDM発生のHRは1.1−1.2 総じて低リスク、中止で改善するものが多い。 CV risk患者では投与の利点が上回ることが多い https://t.co/pSiZrgVMmZ

JM

Jussi Mustonen

@JusiMD · X

@IngaKsd @JuhaniKnuuti @lasleh @laaksotero Sanoit, että - vain 1/100 hyötyisi (katteeton väite) - saisivat paljon haittoja (katteeton väite) Ks. https://t.co/Fh29p4YGqh https://t.co/YUD5Yy9tdm https://t.co/USTF1ntbTo https://t.co/OM5xVx5ly0

DD

David Diamond

@LDLSkeptic · X

@DrScottMurray @lowcarbGP This is a rigorous assessment of new onset T2D, with physiological measures in all subjects pre- vs post statin use. Borderline diabetics more susceptible to develop T2D w/ statin. Why was this not included in the AHA review of statin safety? DOI: 10.1161/ATV.0000000000000073 https://t.co/z27lWjJ2We

DD

David Diamond

@LDLSkeptic · X

@dezina3d @KenDBerryMD @lowcarbGP @drscottyk No mention of Cederberg et al or Goodarzi et al in the 2019 AHA review of statin safety and adverse events - why? @DrAseemMalhotra @ethanjweiss DOI: 10.1161/ATV.0000000000000073 DOI: 10.2337/dc13-0490 https://t.co/y9AdEwDjRr

N

Neurophile

@neurogeekpitou · X

@notaperfectname @doctoctocbot https://t.co/MBNUuiY3oJ

D

Das

@ssdas29 · X

Statin Safety and Associated Adverse Events: A Scientific Statement From the American Heart Association 2018 https://t.co/scTSFsDh4P

MT

Matt Tillotson

@matttillotson · X

RT @NutritionMadeS3: 1 in 4 Americans over 40yo is on a statin (!!!)

RM

Rolando R. Moreno

@RolandoRMoreno · X

RT @NutritionMadeS3: 1 in 4 Americans over 40yo is on a statin (!!!)

AL

Aaron Lepeska

@AaronLepeska · X

RT @NutritionMadeS3: 'Most children in studies evaluating statins had heterozygous FH and were generally otherwise healthy, although of cou…

EA

Evan Allen

@EAllen0417 · X

RT @NutritionMadeS3: 'Most children in studies evaluating statins had heterozygous FH and were generally otherwise healthy, although of cou…

CB

Cantona & Best

@bestcanton7 · X

RT @NutritionMadeS3: 'Most children in studies evaluating statins had heterozygous FH and were generally otherwise healthy, although of cou…

BT

Bhopender Thakur

@TheBhupiThakur · X

RT @NutritionMadeS3: 'Most children in studies evaluating statins had heterozygous FH and were generally otherwise healthy, although of cou…

GP

Gil Carvalho MD PhD

@NutritionMadeS3 · X

'Most children in studies evaluating statins had heterozygous FH and were generally otherwise healthy, although of course, LDL-C levels were very high and lifetime risk of CVD was markedly increased' Dyslipidemia *IS* sufficient https://t.co/CTwyPf9etx

RA

Recruiting Animal

@animal · X

RT @NutritionMadeS3: 1 in 4 Americans over 40yo is on a statin (!!!)

MB

Mark Bennett

@MarkBennett07 · X

RT @NutritionMadeS3: 1 in 4 Americans over 40yo is on a statin (!!!)

DW

Dr. Woodall

@DrWoodallND · X

RT @NutritionMadeS3: 1 in 4 Americans over 40yo is on a statin (!!!)

RN

Rapamycin News

@RapaNews · X

RT @NutritionMadeS3: 1 in 4 Americans over 40yo is on a statin (!!!)

R

RMH

@RonMcHam1955 · X

RT @NutritionMadeS3: 1 in 4 Americans over 40yo is on a statin (!!!)

LL

Lic. Fernando Luna

@NutricionLP · X

RT @NutritionMadeS3: 1 in 4 Americans over 40yo is on a statin (!!!)

GP

Gil Carvalho MD PhD

@NutritionMadeS3 · X

1 in 4 Americans over 40yo is on a statin (!!!)

YR

Yaron Rotman

@NASH_and_coffee · X

@NoureddinMD @juanpabloarab @AlkhouriNaim @DrLoomba @KathleenCoreyMD @DrMTLong @schattenbergJ As always with retrospective studies, you wonder whether it's the #statins that worsen #diabetes, or that pts with an indication for statins are the ones with higher risk of DM progression. Data from RCTs shows ⬆️ risk of DM, but only 0.2 per 1000 PY https://t.co/Qj152EqUSz

TN

Tim Noakes

@ProfTimNoakes · X

RT @LDLSkeptic: @brianedwardsmd @drlabos @nationallipid Stat sig ⬆️ in MMSE (cognition) w/ statin withdrawal followed by a ⬇️in MMSE (impai…

DD

David Diamond

@LDLSkeptic · X

@brianedwardsmd @drlabos @nationallipid Stat sig ⬆️ in MMSE (cognition) w/ statin withdrawal followed by a ⬇️in MMSE (impaired memory) with rechallenge with statin This paper not mentioned in AHA review of statin adverse effects - why? DOI: 10.1161/ATV.0000000000000073 @KenDBerryMD @DrAseemMalhotra @ProfTimNoakes https://t.co/WYtP1CCWFj

DD

David Diamond

@LDLSkeptic · X

@brianedwardsmd @drlabos @nationallipid according to the AHA: cognitive deficits "been examined in several overviews of both RCTs and observational data, with no conclusive evidence for either cognitive benefit or harm from statin therapy." DOI: 10.1161/ATV.0000000000000073

F

fipco

@fipco · X

@Maratosflier @ethanjweiss @RogueRad ESC guidelines say risk of Lp(a)>430 nmol/L similar to HeFH based on this MR study. https://t.co/apVcFYWpKR this review reassuring on cataract risk https://t.co/W17Et6wXPU https://t.co/TsHYSqf9CH

F

fipco

@fipco · X

@Maratosflier @DBelardoMD @DavidLBrownMD I support CAC for subset, not all. CAC could indicate person’s not low risk. Ex: in MESA, ~20% were PCE risk 5-7.5%. CAC ID’s 2 in 5 of those w avg 10y ASCVD risk ~15%. https://t.co/lRp4U47BND CAC cost: $50-150. Good review of statin AEs https://t.co/W17Et6wXPU https://t.co/AcSZtFYja1

KL

Koushik R. Reddy, MD, FACC, FACLM, DipABLM,LMI

@KoushikReddyMD · X

@sandeepvarma15 @dylanarmbruste3 Statins like any other medication, come with their share of side effects. That said, they are among the most studied, if not the most studied medication. Made a huge impact on CV outcomes. Safety profile outliners here... https://t.co/rhDyAOxuhJ

BT

Bhopender Thakur

@TheBhupiThakur · X

RT @Drlipid: Statins and Diabetes: How Big Is the Risk? https://t.co/NmRUOBbkta Also see https://t.co/PZw5enGm17 https://t.co/kmKCsWBdN6

AS

Anzhela Soloveva

@SolovevaAnzhela · X

@SABOURETCardio https://t.co/uJGPg9fXnk https://t.co/psRPIvwLku

PC

Prof Derek Connolly

@DrDerekConnolly · X

@ProfDFrancis this is perhaps a better compendium on the real [minimum] side effect profile of statins atorvastatin 80mg is ~£20 per year in the UK few therapies are this cost effective https://t.co/7aHJRIHX0K

TL

The Mosaic Theory LLC

@mosaictheories · X

Statin Safety and Associated Adverse Events: A Scientific Statement From the American Heart Association | Arteriosclerosis, Thrombosis, and Vascular Biology https://t.co/2Qic3I6OcB

TF

Travis Smith, D.O. FAAEM

@RosenelliEM · X

Aslew of arrhythmias could cause syncope (sick sinus, tachy-brady syndrome, VT, SVT w/ RVR) Article on trying to rule out actual statin-induced myopathy https://t.co/F06hHMz6KQ the highest risk of muscle injury in lovastatin, simvastatin, & atorvastatin: metabolized by CYP3A$.

VS

Vice Star

@sterkev · X

RT @Drlipid: Statins and Diabetes: How Big Is the Risk? https://t.co/NmRUOBbkta Also see https://t.co/PZw5enGm17 https://t.co/kmKCsWBdN6

ME

Meireles-Brandao, MD | PhD | MSc | ESH

@cmbdoctor · X

STATINS and DIABETES https://t.co/ZSHxEnEwQl

DS

Dr. Luiz Silva

@DrLuizSilva1 · X

RT @Drlipid: Statins and Diabetes: How Big Is the Risk? https://t.co/NmRUOBbkta Also see https://t.co/PZw5enGm17 https://t.co/kmKCsWBdN6

PP

Pissed Off PT

@PissedOff_PT · X

RT @Drlipid: Statins and Diabetes: How Big Is the Risk? https://t.co/NmRUOBbkta Also see https://t.co/PZw5enGm17 https://t.co/kmKCsWBdN6

TD

Thomas Dayspring

@Drlipid · X

Statins and Diabetes: How Big Is the Risk? https://t.co/NmRUOBbkta Also see https://t.co/PZw5enGm17 https://t.co/kmKCsWBdN6

AR

Anand Rohatgi

@dranandrohatgi · X

Detailed and contemporary review on statin side effects - Statin Safety and Associated Adverse Events: A Scientific Statement From the American Heart Association | Arteriosclerosis, Thrombosis, and Vascular Biology https://t.co/K8vEjEMnDH

DN

Dr. Spencer Nadolsky

@DrNadolsky · X

@DoctorTro @ethanjweiss Okay read it closer. Wasn’t just TC but also LDL-c. Recent review went into the observational and rct data on statins and adverse effects including neuropathy https://t.co/JaK1kQrE3i

LL

Leopold Leopoldovich

@rajuael_andreu · X

RT @IlindelatorreMD: Seguridad de la estatinas y eventos adversos asociados: una declaración científica de la American Heart Association h…

WL

william e lopez

@williamzepol · X

RT @IlindelatorreMD: Seguridad de la estatinas y eventos adversos asociados: una declaración científica de la American Heart Association h…

AC

Anthony J. Caicedo

@AJCaicedoMD · X

RT @IlindelatorreMD: Seguridad de la estatinas y eventos adversos asociados: una declaración científica de la American Heart Association h…

EJ

Elimar José

@elimarjcampos · X

RT @IlindelatorreMD: Seguridad de la estatinas y eventos adversos asociados: una declaración científica de la American Heart Association h…

DM

Dr. Ilin Gilberto de la Torre M.

@IlindelatorreMD · X

Seguridad de la estatinas y eventos adversos asociados: una declaración científica de la American Heart Association https://t.co/VbwfUhZbj9

JL

Jim Leo

@jleomd · X

For all those convinced that statins are poison: Statin Safety and Associated Adverse Events: A Scientific Statement From the American Heart Association | Arteriosclerosis, Thrombosis, and Vascular Biology https://t.co/nhaXT7jLrb

CP

Cardio-Primària

@catcardiocamfic · X

RT @SIETES7: Statin safety and associated adverse events: a scientific statement from the American Heart Association https://t.co/aesIcEYCC…

AF

Alex Kharlamov MD FESC FACC FEACVI FAHA

@drskharlamov · X

Statin Safety and Associated Adverse Events: A Scientific Statement From the American Heart Association | Arteriosclerosis, Thrombosis, and Vascular Biology https://t.co/p38wAqBz3i

EP

Eva Montané MD, PhD.

@montaneva · X

RT @SIETES7: Revisión negacionista sobre los principales efectos indeseados de las estatinas "Statin safety and associated adverse events:…

SO

Sietes.org

@SIETES7 · X

Revisión negacionista sobre los principales efectos indeseados de las estatinas "Statin safety and associated adverse events: a scientific statement from the American Heart Association" https://t.co/aesIcEYCC0 vía @SIETES7

AC

Alan Cassels

@AKECassels · X

RT @SIETES7: Statin safety and associated adverse events: a scientific statement from the American Heart Association https://t.co/aesIcEYCC…

JG

Juan Gérvas

@JuanGrvas · X

RT @SIETES7: Statin safety and associated adverse events: a scientific statement from the American Heart Association https://t.co/aesIcEYCC…

CD

CARLOS GLEZEIRIS DEL

@deiris2012 · X

RT @txemacoll: RT SIETES7: Statin safety and associated adverse events: a scientific statement from the American Heart Association https://…

T

txemacoll

@txemacoll · X

RT SIETES7: Statin safety and associated adverse events: a scientific statement from the American Heart Association https://t.co/7HlxHRWIzJ vía SIETES7 via sanoysalvoblog

PB

pepe bravo

@pepebravoc · X

RT @SIETES7: Statin safety and associated adverse events: a scientific statement from the American Heart Association https://t.co/aesIcEYCC…

SS

Sano y salvo

@sanoysalvoblog · X

RT @SIETES7: Statin safety and associated adverse events: a scientific statement from the American Heart Association https://t.co/aesIcEYCC…

J

job

@ruralsud · X

RT @SIETES7: Statin safety and associated adverse events: a scientific statement from the American Heart Association https://t.co/aesIcEYCC…

PM

Paco Morales

@16pacomorales · X

Statin Safety and Associated Adverse Events: A Scientific Statement From the American Heart Association | Arteriosclerosis, Thrombosis, and Vascular Biology https://t.co/udpOSBtBp3

JA

jorge aguirre

@jaguirre000 · X

RT @SIETES7: Statin safety and associated adverse events: a scientific statement from the American Heart Association https://t.co/aesIcEYCC…

JA

jorge aguirre

@jaguirre0001 · X

RT @SIETES7: Statin safety and associated adverse events: a scientific statement from the American Heart Association https://t.co/aesIcEYCC…

SO

Sietes.org

@SIETES7 · X

Statin safety and associated adverse events: a scientific statement from the American Heart Association https://t.co/aesIcEYCC0 vía @SIETES7

EV

Erick R. Licona-Vera

@ErickLiconav · X

RT @EstebanDL: https://t.co/XquExs0Bcr Y la defensa de AHA: https://t.co/0wNHU5b5zK

JH

Juan Manuel Hernandez

@JuanmaHernande · X

RT @EstebanDL: https://t.co/XquExs0Bcr Y la defensa de AHA: https://t.co/0wNHU5b5zK

DB

Dr.N.Baqer

@NoahBaqer · X

RT @thameralessa: Statin Safety and Associated Adverse Events: A Scientific Statement From the American Heart Association Helpful informat…

دا

د وليد الضاحي

@Drwaleedaldahi · X

RT @thameralessa: Statin Safety and Associated Adverse Events: A Scientific Statement From the American Heart Association Helpful informat…

DM

Dr. Ilin Gilberto de la Torre M.

@IlindelatorreMD · X

Statin Safety and Associated Adverse Events: A Scientific Statement From the American Heart Association https://t.co/VbwfUhZbj9

HY

hmwr_Yu

@hmwr_Yu · X

RT @pawinpawin: Statement จาก American Heart Association บอกถึงผลข้างเคียงของยาลดไขมันในกลุ่ม Statin จะว่าไป Risk ของ DM ก็เยอะนะเนี่ย @ipa…

دا

د. ثامر العيسى

@thameralessa · X

Statin Safety and Associated Adverse Events: A Scientific Statement From the American Heart Association Helpful information for the clinicians to overcome the fear of statins adverse effects in the public and the misinformations in the social media. https://t.co/AkMtbrV1VM

P

PleJanthra

@PleJanthra · X

RT @pawinpawin: Statement จาก American Heart Association บอกถึงผลข้างเคียงของยาลดไขมันในกลุ่ม Statin จะว่าไป Risk ของ DM ก็เยอะนะเนี่ย @ipa…

P

Pennyyy

@ImPennyyy · X

RT @pawinpawin: Statement จาก American Heart Association บอกถึงผลข้างเคียงของยาลดไขมันในกลุ่ม Statin จะว่าไป Risk ของ DM ก็เยอะนะเนี่ย @ipa…

R

rutt

@all_rut · X

RT @pawinpawin: Statement จาก American Heart Association บอกถึงผลข้างเคียงของยาลดไขมันในกลุ่ม Statin จะว่าไป Risk ของ DM ก็เยอะนะเนี่ย @ipa…

PN

Pawin Numthavaj

@pawinpawin · X

Statement จาก American Heart Association บอกถึงผลข้างเคียงของยาลดไขมันในกลุ่ม Statin จะว่าไป Risk ของ DM ก็เยอะนะเนี่ย @ipats @Golf_rx https://t.co/oTLAyjlejj https://t.co/5uoaTvxorx

森

森　勇一

@ymori117 · X

Arteriosclerosis, Thrombosis, and Vascular Biology 「スタチンの安全性と関連有害事象：米国心臓協会からの科学的声明」 https://t.co/CyC8m8W2WN ものすごく長い（私はくじけました…）。

EH

Emtiro Health

@EmtiroHealth · X

AHA: Statin Safety and Associated Adverse Events: A Scientific Statement From the American Heart Association https://t.co/in953Gl2I8

LC

Luis Davalos CARDIOLOGIA

@KKATODD · X

RT @jvillacastin: Revisión exhaustiva de todos los efectos secundarios que pueden estar asociados a la toma de estatinas. Algunos, por inte…

MY

Mardi Chapman VOTED YES

@mardidiane · X

The final word on #statins - most adverse effects can be reversed by stopping treatment. In contrast, an MI or ischemic #stroke permanently damages the #heart or brain and can be fatal. Benefit outweighs risk https://t.co/2I10IO07lR @American_Heart

BZ

Boback Ziaeian

@boback · X

@CaptRockyBob @egundeck @venkmurthy @khurramn1 @VietHeartPA @MichaelJBlaha @mdmiedema @DavidLBrownMD @rauldsf_santos @almallahmo @MBittencourtMD @MethodistHosp @NadeenFaza @MasriAhmadMD @WilliamZoghbi @pabeda1 @JJheart_doc @pnatarajanmd @gcfmd @thebyrdlab https://t.co/tYQwgNk263