7. But there is also evidence regarding immune system differences between men and women which we also discuss in the piece https://t.co/fGGvAYkXcc
The X chromosome and sex-specific effects in infectious disease susceptibility.
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Jan 2019 – Sep 2025Where it's discussed
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News41 articles
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X / Twitter29 posts
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AI synopsis
What people are saying
Throughout the discussions, participants emphasize the significance of the X chromosome in immune function and disease differences between sexes, with phrases like 'largest number of immune-related genes' and 'genes escape inactivation,' indicating a focus on genetic mechanisms. Many comments express curiosity about how these findings relate to sex disparities in conditions like COVID-19, showing high interest. Some posts suggest the research could lead to new diagnostic or therapeutic approaches, highlighting a perception of meaningful impact.
Most posts strongly agree or acknowledge the significance of the research, highlighting the importance of the X chromosome in immune response and disease susceptibility.
The discussions show high curiosity, referencing specific genetic mechanisms and potential implications for disease disparities, indicating they find the topic highly relevant.
Several comments mention molecular details or suggest the findings could inform future studies, reflecting thoughtful engagement, though most are observational rather than in-depth.
While some recognize the potential relevance for understanding sex-based health disparities, the overall perception is that this research could have meaningful, albeit not immediate, impact on healthcare and genetic studies.
Abstract in brief
- The X chromosome contains many immune-related genes that affect how our bodies respond to infectious diseases, but it’s often overlooked in genetic studies because analyzing it is complicated.
- Females have a unique genetic setup called X inactivation, where one of their X chromosomes is mostly turned off, but some genes escape this process, potentially giving females an immunological advantage over males.
- The review discusses how the X chromosome influences immune responses and the differences between sexes in susceptibility to infections, using tuberculosis as an example of male dominance in disease risk that is not yet fully understood.]
Top posts
Most liked on X and Bluesky12. Meanwhile, experts who study gender and infectious disease highlight immune system differences in men and women. Lot of evidence of this. https://t.co/fGGvAY3mkE
25/ produkcją przeciwciał. Na podstawie 1.https://t.co/l7RSqcj7uB 2.https://t.co/ot3tZweoEW 3.https://t.co/Cgjlvn0iqH 4.https://t.co/IcmhxQTM8K 5.https://t.co/okQ0pSkNPo 6.https://t.co/Lrv35172Lg
@ChrispiaKane @suzanne_moore There's a growing body of research into the chromosomal nature of sex-differentiated immune response. X chromosome carries many immunity-related genes. Conversely it's likely also why women are more at risk from autoimmune disease https://t.co/DJo8p8OL4o https://t.co/L8AYFQUdb7
@bevcott @markoftheD X inactivation isn’t a perfect process, and sometimes genes on the X chromosome escape inactivation. In this case, a female ends up with two active copies of a particular gene - this is a good paper on the X https://t.co/5VFpuVK28s
@HSTSsn19561 @ape_bass @BanrighMessy @_Mars_F That’s not pedantic. It’s the finding of more recent studies. https://t.co/13blwMly7z
All mentions
X Chromosome and Sex Differences in Infectious Disease Response
COVID-19 hits men harder than women, possibly linked to genetic factors. The X chromosome contains immune-related genes that influence disease susceptibility, with females potentially having an immunological advantage…
Sex-Specific Genetic Factors in Infectious Disease Susceptibility
The X chromosome contains many immune-related genes affecting responses to infections. Females' X inactivation and gene escape may provide immunological advantages, influencing disease susceptibility between sexes, such…
@01xNithin @DudespostingWs Sources Cited, hbu?: https://t.co/8XGc1MBgAK (X chromosome has largest number of immuno-related genes in human genome) https://t.co/iLv5vx81rT (Many diseases present with a clear sex bias) https://t.co/zETQ8CiXYr (X chromosome-linked diseases are usually restricted to males)
@Molson_Hart One major reason is because of the X Chromosome https://t.co/FQQdGJGa7j
感染症感受性でX染色体と性特異的影響 https://t.co/UFlArQBO5V
25/ produkcją przeciwciał. Na podstawie 1.https://t.co/l7RSqcj7uB 2.https://t.co/ot3tZweoEW 3.https://t.co/Cgjlvn0iqH 4.https://t.co/IcmhxQTM8K 5.https://t.co/okQ0pSkNPo 6.https://t.co/Lrv35172Lg
https://t.co/7Li1y3vOmY
@HSTSsn19561 @ape_bass @BanrighMessy @_Mars_F That’s not pedantic. It’s the finding of more recent studies. https://t.co/13blwMly7z
Could this 2019 paper on the X chromosome & sex-specific effects in infectious disease susceptibility offer leads in the significant dispartity in covid-19 mortality between the sexes? https://t.co/hr8SY59i1Z #coronavirus
@annaonde Nesse caso, se estiver falando de letalidade, há a possibilidade das mulheres terem uma resposta imunológica mais rápida e potente que a dos homens. Há algumas diferenças genéticas nessa área. Da uma olhada nesse estudo, Doi: 10.1186/s40246-018-0185-z
RT @franklincrick: @bevcott @markoftheD X inactivation isn’t a perfect process, and sometimes genes on the X chromosome escape inactivation…
@bevcott @markoftheD X inactivation isn’t a perfect process, and sometimes genes on the X chromosome escape inactivation. In this case, a female ends up with two active copies of a particular gene - this is a good paper on the X https://t.co/5VFpuVK28s
@Rose_Posting @GellmanRebecca @Ysm0F @notCursedE @DebbieHayton @zoekennedy @NJHenpointe @2damntrans https://t.co/uMNAbqtFnO
https://t.co/nEtucqB9jd
RT @chriscmooney: 12. Meanwhile, experts who study gender and infectious disease highlight immune system differences in men and women. Lot…
RT @chriscmooney: 12. Meanwhile, experts who study gender and infectious disease highlight immune system differences in men and women. Lot…
RT @chriscmooney: 12. Meanwhile, experts who study gender and infectious disease highlight immune system differences in men and women. Lot…
12. Meanwhile, experts who study gender and infectious disease highlight immune system differences in men and women. Lot of evidence of this. https://t.co/fGGvAY3mkE
@Cernovich The X chromosome and sex-specific effects in infectious disease susceptibility https://t.co/gbcZvu4jQt
@johnvoelcker Aside from lifestyle differences (48% of men in China smoking vs 2% of women, etc.), I think the most interesting theory is that an extra X chromosome strengthens the immune system. https://t.co/tfcscDTb5o
RT @chriscmooney: 7. But there is also evidence regarding immune system differences between men and women which we also discuss in the piec…
RT @chriscmooney: 7. But there is also evidence regarding immune system differences between men and women which we also discuss in the piec…
RT @chriscmooney: 7. But there is also evidence regarding immune system differences between men and women which we also discuss in the piec…
RT @chriscmooney: 7. But there is also evidence regarding immune system differences between men and women which we also discuss in the piec…
RT @chriscmooney: 7. But there is also evidence regarding immune system differences between men and women which we also discuss in the piec…
7. But there is also evidence regarding immune system differences between men and women which we also discuss in the piece https://t.co/fGGvAYkXcc
RT @LauraSwinton: @ChrispiaKane @suzanne_moore There's a growing body of research into the chromosomal nature of sex-differentiated immune…
@ChrispiaKane @suzanne_moore There's a growing body of research into the chromosomal nature of sex-differentiated immune response. X chromosome carries many immunity-related genes. Conversely it's likely also why women are more at risk from autoimmune disease https://t.co/DJo8p8OL4o https://t.co/L8AYFQUdb7
The X chromosome and sex-specific effects in infectious disease susceptibility | Human Genomics | Full Text https://t.co/ZqSNJnMuTx
"The X chromosome may contribute to the missing heritability or contain biomarkers that could be used as diagnostic tools. As... https://t.co/SNB3gkq7R8
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