January 2019 PMID 30667501

Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review and Meta-analysis.

Sean L Zheng, Alistair J Roddick

Mentions

215
Peak: 35 in Jan 2019
across 6 sources since Jan 2019

Extended reach

742,263
potential audience

Total likes

94

Video views

1,235

Mentions per month

Jan 2019 – Aug 2025

Where it's discussed

  • News110 articles
  • X / Twitter60 posts
  • Facebook29 posts
  • Blogs12 articles
  • YouTube2 videos
  • Reddit2 posts

AI synopsis

What people are saying

The overall tone indicates caution and skepticism, with many discussions emphasizing the increased bleeding risks associated with aspirin, such as 'Aspiryna nawet w mniejszej dawce zwiększa ryzyko poważnego krwawienia,' and noting the lack of clear overall benefit, as reflected in phrases like 'Another nail in the coffin.' The tone and word choice suggest users are critically reflecting on the publication’s findings, but without deep engagement or broad impact.

AgreementLow agreement

Most discussions highlight the risks associated with aspirin use, especially bleeding, suggesting some skepticism about its benefits as a preventive measure.

InterestModerate interest

There is moderate interest, as users are engaging with the topic mainly through sharing summaries and basic opinions without deep analysis.

EngagementNeutral engagement

The level of engagement appears limited; most contributions are reposts or brief comments without detailed analysis or personal input.

ImpactLow impact

The overall influence of these discussions seems relatively low, likely affecting awareness more than policy or practice.

Abstract in brief

  • This study reviews multiple clinical trials to evaluate whether taking aspirin for primary prevention of cardiovascular disease reduces heart attacks, strokes, and death, but also increases the risk of serious bleeding.
  • The analysis found that aspirin use modestly decreases the risk of major cardiovascular events, but it also significantly raises the likelihood of major bleeding, leading to a careful weighing of benefits versus risks.
  • Overall, while aspirin can lower some cardiovascular risks, its potential to cause harmful bleeding means healthcare providers and patients need to consider individual risk factors before deciding on aspirin for prevention.

Top posts

Most liked on X and Bluesky
Paweł Basiukiewicz
@PBasiukiewicz · X

Aspiryna spełnia zarówno 1. jak i 2. kryterium, takich przykładów zresztą jest więcej. Aspiryna nawet w małej dawce zwiększa ryzyko poważnego krwawienia. Zresztą nie ma działającego leku bez działań niepożądanych. https://t.co/dh6a9cb50a

Jan 1, 2023 · 27 likes · 1 share · 47,536 followers View post →
Hilario Badiola
@hilariobad59 · X

@JAMA_current AAS en prevención 1 no beneficio global, < riesgo de eventos CV, pero > riesgo de sangrado y sin efecto sobre riesgo de cáncer Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events https://t.co/yVPGMEFNCZ

Jan 25, 2019 · 11 likes · 8 shares · 187 followers View post →
American Thoracic Society (ATS)
@atscommunity · X

Association of aspirin use for primary prevention with cardiovascular events and bleeding events: https://t.co/52QFxYK81e

Jan 24, 2019 · 4 likes · 3 shares · 41,966 followers View post →
Prof. Wasim Hanif
@docwas · X

Is it time to re-visit use of Aspirin in primary prevention? Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review and Meta-analysis. | Cardiology | JAMA | JAMA Network https://t.co/qvA4TESpRv

Jan 28, 2019 · 4 likes · 2 shares · 5,030 followers View post →
Dr Jean Pierre Laroche #vacciné 6.0
@Echoraljpangio · X

Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding EventsA Systematic... https://t.co/xMSGzA6ykS

May 1, 2019 · 2 likes · 1 share · 2,713 followers View post →
にいやん
@niiyan51 · X

Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review and Meta-analysis. - PubMed - NCBI https://t.co/vQ6oUpFDDN

Sep 7, 2019 · 2 likes · 1 share · 1,074 followers View post →

All mentions

Cardiology Updates: Key Research and Guidelines

Café com Journal offers updates on the latest cardiology news published in leading journals. In this session, we discuss significant findings, including a systematic review on aspirin use for primary prevention of…

CardioLearning · Jan 29, 2019 456 views
Pani Hania
@HMaegerle · X

RT @PBasiukiewicz: Aspiryna spełnia zarówno 1. jak i 2. kryterium, takich przykładów zresztą jest więcej. Aspiryna nawet w małej dawce zwi…

Jan 2, 2023 · 1 share · 9,074 followers View post →
Paweł Basiukiewicz
@PBasiukiewicz · X

Aspiryna spełnia zarówno 1. jak i 2. kryterium, takich przykładów zresztą jest więcej. Aspiryna nawet w małej dawce zwiększa ryzyko poważnego krwawienia. Zresztą nie ma działającego leku bez działań niepożądanych. https://t.co/dh6a9cb50a

Jan 1, 2023 · 27 likes · 1 share · 47,536 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @CanadaRna: Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review and Me…

Dec 3, 2020 · 1 share · 6,714 followers View post →
Canada RNA Biochemical Inc.
@CanadaRna · X

Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review and Meta-analysis https://t.co/UfcMnHDCv5 https://t.co/zHPaJ4y30A

Dec 3, 2020 · 1 share · 19 followers View post →
Jhongert Alza Arcila
@jhongert · X

Para leer con

Jan 11, 2020 · 1,320 followers View post →
Taku Asano
@ta_brilliantsea · X

Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic... https://t.co/tncJ5fev4U

Dec 26, 2019 · 26 followers View post →
Frank Sotzik
@WordsByFrank · X

Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic... https://t.co/0KDCbtZGsw

Dec 25, 2019 · 4,305 followers View post →
Dr Jean Pierre Laroche #vacciné 6.0
@Echoraljpangio · X

Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic... https://t.co/drP8mbDn3P

Dec 18, 2019 · 1 share · 2,713 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @niihara51: Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review and Me…

Sep 7, 2019 · 1 share · 6,714 followers View post →
にいやん
@niiyan51 · X

Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review and Meta-analysis. - PubMed - NCBI https://t.co/vQ6oUpFDDN

Sep 7, 2019 · 2 likes · 1 share · 1,074 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @hataboSAN: Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review and Me…

Aug 18, 2019 · 1 share · 6,714 followers View post →
hataboSAN
@hataboSAN · X

Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review and Meta-analysis. https://t.co/nqaRF7jVpR

Aug 18, 2019 · 1 share · 997 followers View post →
Ray DuBois, MD, PhD
@Rndubois · X

Association of #Aspirin Use for Primary Prevention With #Cardiovascular Events and Bleeding Events:  https://t.co/6WfXJ6p6RJ

Jun 17, 2019 · 5,571 followers View post →
Airiau Caroline
@caroairiau · X

RT @Echoraljpangio: Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding EventsA Systematic... https:/…

May 1, 2019 · 1 share · 1,474 followers View post →
Dr Jean Pierre Laroche #vacciné 6.0
@Echoraljpangio · X

Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding EventsA Systematic... https://t.co/xMSGzA6ykS

May 1, 2019 · 2 likes · 1 share · 2,713 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @Sefap_FAP: (SIETES) Association of aspirin use for primary prevention with cardiovascular events and bleeding events: a systematic revi…

Feb 20, 2019 · 1 share · 6,714 followers View post →
SEFAP
@Sefap_FAP · X

(SIETES) Association of aspirin use for primary prevention with cardiovascular events and bleeding events: a systematic review and meta-analysis https://t.co/xsZDUypT31

Feb 20, 2019 · 1 like · 1 share · 7,953 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @moisesjimenezs: Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review a…

Feb 9, 2019 · 1 share · 6,714 followers View post →
Moises Jimenez
@moisesjimenezs · X

Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review and Meta-analysis. | Cardiology | JAMA | JAMA Network https://t.co/LPWKc6laFH

Feb 9, 2019 · 1 share · 1,994 followers View post →
PEPID LLC
@pepid_llc · X

Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events via @JAMANetworkOpen https://t.co/16sxT9KrI2 https://t.co/drVOkl8iBA

Feb 8, 2019 · 998 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @SatrupaRagoona1: Recent #meta-analysis shows that #aspirin use in high risk and low risk groups including #diabetes reduces risk of CVD…

Feb 6, 2019 · 1 share · 6,714 followers View post →
Satrupa Ragoonanan
@SatrupaRagoona1 · X

Recent #meta-analysis shows that #aspirin use in high risk and low risk groups including #diabetes reduces risk of CVD (NNT 265) but also increases risk of major bleeding (NNH at 210). Aspirin should not be routinely recommended in primary prevention. doi:10.1001/jama.2018.20578

Feb 6, 2019 · 2 likes · 1 share · 23 followers View post →
Jos Kleijnen
@JosKleijnen · X

RT @KSREvidence: Our #AppraisaloftheDay: A @JAMA_current #systematicreview rated at high risk of #bias. Pooled analysis reported a ⬇️risk…

Feb 5, 2019 · 2 shares · 429 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @KSREvidence: Our #AppraisaloftheDay: A @JAMA_current #systematicreview rated at high risk of #bias. Pooled analysis reported a ⬇️risk…

Feb 5, 2019 · 2 shares · 6,714 followers View post →
KSR Evidence
@KSREvidence · X

Our #AppraisaloftheDay: A @JAMA_current #systematicreview rated at high risk of #bias. Pooled analysis reported a ⬇️risk of CV events but ⬆️risk of major bleeding in the prevention of #cardiovascular disease using #aspirin. Available to all for 1 day at https://t.co/k8kSLmvj4D https://t.co/pRslblXODI

Feb 5, 2019 · 1 like · 2 shares · 361 followers View post →
zoonifer khan
@zoonifer · X

Aspirin use is associated with high risk of bleeding events in patients without #Cardiovasculardisease. DOI: 10.1001/jama.2018.20578

Feb 2, 2019 · 1 like · 15 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @docwas: Is it time to re-visit use of Aspirin in primary prevention? Association of Aspirin Use for Primary Prevention With Cardiovascu…

Jan 28, 2019 · 2 shares · 6,714 followers View post →
Prof. Wasim Hanif
@docwas · X

Is it time to re-visit use of Aspirin in primary prevention? Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review and Meta-analysis. | Cardiology | JAMA | JAMA Network https://t.co/qvA4TESpRv

Jan 28, 2019 · 4 likes · 2 shares · 5,030 followers View post →
Medical Evidence
@Medical_Mei · X

Association of #Aspirin Use for Primary Prevention With #Cardiovascular Events and #Bleeding Events @JAMANetwork https://t.co/2MAWJdB9Hc

Jan 27, 2019 · 412 followers View post →
Ian medical
@IanMedical · X

RT @NNTonthefly: New NNT→Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Rev…

Jan 26, 2019 · 3 shares · 409 followers View post →
James Deardorff
@wjdeardorff · X

"Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events" - https://t.co/SxfIgN5252 https://t.co/ewzGbnkcYe

Jan 26, 2019 · 706 followers View post →
Robson Zanoli
@razanoli · X

RT @hilariobad59: @JAMA_current AAS en prevención 1 no beneficio global, < riesgo de eventos CV, pero > riesgo de sangrado y sin efecto s…

Jan 26, 2019 · 8 shares · 172 followers View post →
Juan Pedro Romero
@JuanPedroRome20 · X

RT @hilariobad59: @JAMA_current AAS en prevención 1 no beneficio global, < riesgo de eventos CV, pero > riesgo de sangrado y sin efecto s…

Jan 26, 2019 · 8 shares · 204 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @karacagurkan: Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review and…

Jan 26, 2019 · 1 share · 6,714 followers View post →
carol
@carolinaxipell · X

RT @hilariobad59: @JAMA_current AAS en prevención 1 no beneficio global, < riesgo de eventos CV, pero > riesgo de sangrado y sin efecto s…

Jan 26, 2019 · 8 shares · 59 followers View post →
Laparostato⚕️
@laparostato · X

RT @hilariobad59: @JAMA_current AAS en prevención 1 no beneficio global, < riesgo de eventos CV, pero > riesgo de sangrado y sin efecto s…

Jan 26, 2019 · 8 shares · 1,845 followers View post →
drgurkankaraca
@karacagurkan · X

Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review and Meta-analysis. https://t.co/xXFwdkdPvI

Jan 26, 2019 · 1 share · 651 followers View post →
Paco Cañestro
@fcanestro · X

RT @hilariobad59: @JAMA_current AAS en prevención 1 no beneficio global, < riesgo de eventos CV, pero > riesgo de sangrado y sin efecto s…

Jan 26, 2019 · 8 shares · 2,184 followers View post →
Adrián Zuno
@AdrianZuno · X

RT @hilariobad59: @JAMA_current AAS en prevención 1 no beneficio global, < riesgo de eventos CV, pero > riesgo de sangrado y sin efecto s…

Jan 26, 2019 · 8 shares · 676 followers View post →
JAMA
@JAMA_current · X

RT @hilariobad59: @JAMA_current AAS en prevención 1 no beneficio global, < riesgo de eventos CV, pero > riesgo de sangrado y sin efecto s…

Jan 26, 2019 · 8 shares · 488,088 followers View post →
Carmen Alcaraz-L
@Mencitas · X

RT @NNTonthefly: New NNT→Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Rev…

Jan 25, 2019 · 3 shares · 794 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @AARONLYL: Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review and Met…

Jan 25, 2019 · 1 share · 6,714 followers View post →
Aaron Liew MB BCh, MPH, PhD
@AARONLYL · X

Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review and Meta-analysis. | Cardiology | JAMA | JAMA Network https://t.co/u1kgbMJ0Fy

Jan 25, 2019 · 1 share · 98 followers View post →
Hilario Badiola
@hilariobad59 · X

@JAMA_current AAS en prevención 1 no beneficio global, < riesgo de eventos CV, pero > riesgo de sangrado y sin efecto sobre riesgo de cáncer Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events https://t.co/yVPGMEFNCZ

Jan 25, 2019 · 11 likes · 8 shares · 187 followers View post →
Medical Evidence
@Medical_Mei · X

Association of #Aspirin Use for Primary Prevention With #Cardiovascular Events and #Bleeding Events @JAMANetwork https://t.co/2MAWJdB9Hc

Jan 25, 2019 · 412 followers View post →
ATI14
@ProfAnestesista · X

Association of #Aspirin Use for Primary Prevention With #Cardiovascular Events and #Bleeding Events @JAMANetwork https://t.co/5qyUFUr92N

Jan 25, 2019 · 604 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @HematologiaMex: Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review a…

Jan 24, 2019 · 1 share · 6,714 followers View post →
HematoTuits
@HematologiaMex · X

Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review and Meta-analysis. | Cardiology | JAMA | JAMA Network https://t.co/enZraMUA3M

Jan 24, 2019 · 1 like · 1 share · 883 followers View post →
Firas Aljanadi
@firasaljanadi · X

RT @atscommunity: Association of aspirin use for primary prevention with cardiovascular events and bleeding events: https://t.co/52QFxYK81e

Jan 24, 2019 · 3 shares · 423 followers View post →
American Thoracic Society (ATS)
@atscommunity · X

Association of aspirin use for primary prevention with cardiovascular events and bleeding events: https://t.co/52QFxYK81e

Jan 24, 2019 · 4 likes · 3 shares · 41,966 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @SophieParkUCL: Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review an…

Jan 23, 2019 · 1 share · 6,714 followers View post →
Sophie Park
@SophieParkOx · X

Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review and Meta-analysis. | Cardiology | JAMA | JAMA Network https://t.co/54HdcTVHhr

Jan 23, 2019 · 1 like · 1 share · 460 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @NNTonthefly: New NNT→Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Rev…

Jan 23, 2019 · 3 shares · 6,714 followers View post →
NNTonthefly
@NNTonthefly · X

New NNT→Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review and Meta-analysis. https://t.co/kwmTkh1c2J

Jan 23, 2019 · 2 likes · 3 shares · 473 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @OSHP_LEAD: Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review and Me…

Jan 23, 2019 · 1 share · 6,714 followers View post →
OSHP OK Pharmacists
@OSHP_LEAD · X

Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review and Meta-analysis https://t.co/s8uoSW73tp

Jan 23, 2019 · 1 share · 56 followers View post →
dario pasqualini
@dipi1_con · X

Association of #Aspirin Use for Primary Prevention With #Cardiovascular Events and #Bleeding Events @JAMANetwork https://t.co/BniaDewU14 https://t.co/mFZSQ42IP3

Jan 23, 2019 · 139 followers View post →
Szabolcs Sandoly
@sandoly · X

RT @2Scottish: Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review and Me…

Jan 22, 2019 · 2 shares · 2,430 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @2Scottish: Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review and Me…

Jan 22, 2019 · 2 shares · 6,714 followers View post →
Scott Cameron
@2Scottish · X

Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review and Meta-analysis. | Cardiology | JAMA | JAMA Network. Another nail in the coffin. https://t.co/rqE1jmp5oV

Jan 22, 2019 · 2 shares · 2,113 followers View post →