Anesthesiology June 2019 PMID 30694851

Understanding the Effects of General Anesthetics on Cortical Network Activity Using Ex Vivo Preparations.

Logan J Voss, Paul S García, Harald Hentschke, Matthew I Banks

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Mentions

Peak: 2 in Jun 2019

across 3 sources since Jan 2019

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45,706

potential audience

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539

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Jan 2019 – Sep 2019

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AI synopsis

What people are saying

The overall tone suggests a shared appreciation for the study’s contribution to understanding how anesthetics disrupt neural communication, with posts mentioning the significance of ex vivo models and cortical activity, and words like 'important' and 'comprehensive' indicating acknowledgment of its potential to inform anesthesia practices.

AgreementModerate agreement

Most discussions recognize the significance of the research, emphasizing its contributions to understanding anesthesia mechanisms, indicating general agreement with its importance.

InterestModerate interest

The discussions reflect a moderate level of curiosity, with some posts highlighting key aspects like cortical communication, but they do not delve deeply into novel or complex details.

EngagementModerate engagement

Participants most frequently share summaries and praise, showing a respectful but somewhat surface-level engagement without extensive critical analysis.

ImpactModerate impact

The industry and academic community appear to see this research as relevant, potentially shaping future studies or clinical understanding, though concrete impacts are not explicitly stated.

Abstract in brief

The paper explores how general anesthetics affect brain activity, particularly in the cortex, and suggests that their primary effect is disrupting communication within and between cortical regions, which leads to unconsciousness.
Evidence from brain slice experiments shows that different anesthetics, despite having various molecular targets, all impair neural communication, highlighting a common underlying mechanism.
The authors believe that understanding these effects through ex vivo (outside the living organism) studies can help unify knowledge of anesthesia practices and the neural basis of consciousness, although many questions still remain.]

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All mentions

Molecular Insights into Anesthesia Effects on Cortex Networks

Brain slices reveal how general anesthetics disrupt communication in cortical networks, leading to unconsciousness. The study highlights common mechanisms despite different molecular targets, aiding understanding of…

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@wahyuwei · X

Understanding the Effects of General Anesthetics on Cortical Network Activity Using Ex Vivo Preparations https://t.co/PS77BITcfs

Sep 7, 2019 · 185 followers View post →

Andy Lim

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RT @ALNanesthesia: #ReviewArticle: Understanding the effects of general #anesthetics on cortical network activity using ex vivo preparation…

Jun 26, 2019 · 1 share · 86 followers View post →

Anesthesiology Journals

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Jun 25, 2019 · 1 share · 38,305 followers View post →

EurekaMag

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Understanding the Effects of General Anesthetics on Cortical Network Activity Using Ex Vivo Preparations https://t.co/4AbwaXF31s #eurekamag https://t.co/NW0IkjaEz6

Mar 8, 2019 · 6,546 followers View post →

Proteins InVivo InVitro

@BVpapers · X

Understanding the Effects of General Anesthetics on Cortical Network Activity Using Ex Vivo Preparations.: Understanding the Effects of General Anesthetics on Cortical Network Activity Using Ex Vivo Preparations. Anesthesiology. 2019 Jan 28;: Authors:… https://t.co/W88ILCxGUW https://t.co/vrbrEsxHVo

Jan 30, 2019 · 42 followers View post →