PubHawk
Trials February 2019 PMID 30777118

Impact of two oral doses of 100,000 IU of vitamin D in preschoolers with viral-induced asthma: a pilot randomised controlled trial.

Francine Monique Ducharme, Megan Jensen, Geneviève Mailhot, Nathalie Alos, John White, Elizabeth Rousseau, Sze Man Tse, Ali Khamessan, Benjamin Vinet

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Mentions

12
Peak: 5 in Mar 2020
across 3 sources since Feb 2019

Extended reach

20,509
potential audience

Total likes

562

Video views

9,428

Mentions per month

Feb 2019 – May 2025

Where it's discussed

  • X / Twitter6 posts
  • YouTube4 videos
  • Reddit2 posts

AI synopsis

What people are saying

The discussions reflect curiosity about the safety and efficacy of high-dose vitamin D, with comments referencing safety reports and comparison to other dosing methods. The tone is cautious but open, with mentions of safety, study design, and potential benefits, indicating moderate engagement and interest without asserting a strong consensus or significant impact.

AgreementNeither agree nor disagree

Posts generally recognize the study's findings but do not strongly endorse or dismiss its conclusions, indicating moderate agreement.

InterestModerate interest

Discussions show curiosity about high-dose vitamin D and their effects, reflecting some interest but not widespread enthusiasm.

EngagementModerate engagement

Comments mention specific aspects like safety, dosage, and comparisons to other studies, demonstrating moderate engagement.

ImpactNeutral impact

While some posts highlight potential clinical relevance, the overall discussion does not suggest a profound or immediate impact.

Abstract in brief

  • This study tested whether giving high doses of vitamin D (two doses of 100,000 IU, one in fall and one in winter) can effectively increase vitamin D levels in preschoolers with viral-induced asthma, while also monitoring safety.
  • Results showed that children who received vitamin D had a significant increase in their blood vitamin D levels shortly after dosing, with a larger percentage reaching sufficient levels (above 75 nmol/L) compared to the placebo group, although this difference was less clear at later points.
  • The intervention was safe, with no serious side effects like hypercalcemia, and the study suggests that high-dose vitamin D could be a promising way to improve vitamin D status in these kids, potentially helping manage asthma exacerbations.]
Read the full abstract

Top posts

Most liked on X and Bluesky
Deborah Mahmoudieh
@DeborahMahmoud1 · X

@Nyct0phil3_ @StarryGryffin Impact of two oral doses of 100,000 IU of vitamin D3 in preschoolers with viral-induced asthma: a pilot randomised controlled trial https://t.co/q6LlboBRtY

Mar 16, 2020 · 1 like · 1,916 followers View post →
BioMassSpec
@realBioMassSpec · X

Impact of two oral doses of 100,000 IU of vitamin D3 in preschoolers with viral-induced asthma: a pilot randomised controlled trial #Trials #MassSpec https://t.co/GHq5HBKCVj

Feb 20, 2019 · 5,961 followers View post →
Deborah Mahmoudieh
@DeborahMahmoud1 · X

@daverain @davethedjclark Check: https://t.co/q6LlboBRtY

Mar 16, 2020 · 1,916 followers View post →
Eve.S.
@yeeseak · X

@WildPersistence @Madam_Mito @JavierMtzLpz I also have a sublingual NR 1 spray 4 times/ day ( total equal to 50 mg ribose). Yes. In the hospital for severe chest infection there s 100, 000 iu Vit D stat dose given to adult patients. N a friend reported improvement the next day https://t.co/zsj1Hm3Yuy

Dec 1, 2023 · 880 followers View post →
Kasia Ballou
@KasiaBallou · X

@SimonFili @mattwridley @JimBethell @MattHancock I haven't heard of comparative analysis studies. However, I have read studies where patients were given only two single VERY large doses of vitamin D (100,000IU) over the course of study vs. taking them daily to ensure compliance. Here's an example: https://t.co/7y7Nh6lKYr

May 5, 2020 · 386 followers View post →
James M Isaacs
@JamesMIsaacs1 · X

https://t.co/kGrz9QPV4r

Aug 2, 2020 · 3 followers View post →

All mentions

Eve.S.
@yeeseak · X

@WildPersistence @Madam_Mito @JavierMtzLpz I also have a sublingual NR 1 spray 4 times/ day ( total equal to 50 mg ribose). Yes. In the hospital for severe chest infection there s 100, 000 iu Vit D stat dose given to adult patients. N a friend reported improvement the next day https://t.co/zsj1Hm3Yuy

Dec 1, 2023 · 880 followers View post →
James M Isaacs
@JamesMIsaacs1 · X

https://t.co/kGrz9QPV4r

Aug 2, 2020 · 3 followers View post →
Kasia Ballou
@KasiaBallou · X

@SimonFili @mattwridley @JimBethell @MattHancock I haven't heard of comparative analysis studies. However, I have read studies where patients were given only two single VERY large doses of vitamin D (100,000IU) over the course of study vs. taking them daily to ensure compliance. Here's an example: https://t.co/7y7Nh6lKYr

May 5, 2020 · 386 followers View post →
Deborah Mahmoudieh
@DeborahMahmoud1 · X

@Nyct0phil3_ @StarryGryffin Impact of two oral doses of 100,000 IU of vitamin D3 in preschoolers with viral-induced asthma: a pilot randomised controlled trial https://t.co/q6LlboBRtY

Mar 16, 2020 · 1 like · 1,916 followers View post →
Deborah Mahmoudieh
@DeborahMahmoud1 · X

@daverain @davethedjclark Check: https://t.co/q6LlboBRtY

Mar 16, 2020 · 1,916 followers View post →
BioMassSpec
@realBioMassSpec · X

Impact of two oral doses of 100,000 IU of vitamin D3 in preschoolers with viral-induced asthma: a pilot randomised controlled trial #Trials #MassSpec https://t.co/GHq5HBKCVj

Feb 20, 2019 · 5,961 followers View post →
My orthopedist prescribed me a dose of 600,000 IU of vitamin D ...
Reddit

... 10.1186/s13063-019-3184-z#Sec1. The Miraculous Results of Extremely High Doses of Vitamin D3: A Year Long Experiment with Huge Doses of the ...

Dec 16, 2022 View →
What does of vitimin D3 you taking? I thought 5000iu was high. : r ...
Reddit

... 10.1186/s13063-019-3184-z#Sec1. The Miraculous Results of Extremely High Doses of Vitamin D3: A Year Long Experiment with Huge Doses of the ...

Dec 11, 2022 View →