Here's a commentary on bat tolerance to viral infections https://t.co/6paOxnjEa7 after excellent work by Ahn et al. Nat. Microbiol. https://t.co/ipItmvX5e2
Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host.
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Feb 2019 – May 2025Where it's discussed
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X / Twitter33 posts
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News26 articles
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Blogs8 articles
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YouTube2 videos
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AI synopsis
What people are saying
Across the discussions, posters consistently highlight the significance of the dampened NLRP3 inflammasome in bats, describing it as a key mechanism for their ability to host viruses without severe disease. Words like 'revolutionary' and mentions of 'implications for longevity and viral reservoirs' reflect a shared excitement about potential breakthroughs, while technical references to gene alterations and immune responses demonstrate deep engagement with the research.
Many discussions praise the findings, highlighting the significance of bats' unique immune response and suggesting consensus on its importance.
The topic draws high interest, with posts mentioning the relevance to disease resistance, COVID-19, and implications for understanding viral reservoirs.
Posts show deep engagement by referencing specific immunological concepts like the NLRP3 inflammasome and comparing bat physiology to human responses, indicating thoughtful consideration.
The discussions recognize the potential impact on virology, immunology, and even public health, with posts calling it 'revolutionary' and noting its implications for future research.
Abstract in brief
- Bats have a unique ability to host emerging viruses and show a significantly reduced activation of the NLRP3 inflammasome, which is involved in inflammation, compared to humans and mice.
- This dampened inflammasome response in bats is caused by changes in the NLRP3 gene, including lower gene activity, a new splice variant, and alterations in specific protein domains, allowing bats to control inflammation without affecting viral loads.
- These findings suggest that bats' reduced inflammatory response may be linked to their longevity and their role as viral reservoirs, providing insight into how they manage emerging infections without severe disease.
Top posts
Most liked on X and BlueskyWhy bats don’t care about #COVID19 Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host | Nature Microbiology https://t.co/psozPJYtbH
@MLConradLab Amongst other things, I am a #bat #immunologist. We have shown most bat species pretty actively try and kill the inflammasome. https://t.co/UDNXlEes98 Inspiration: @VirusesImmunity @FGinhoux @cadutertre @VirusWhisperer @IdoAmitLab @LabBroz @hornung_lab & more not on twitter!
11/ What makes bats special might not be their antiviral ability, but rather their antidisease features. https://t.co/CXds4LdLDG https://t.co/jj3nFGR0wY https://t.co/7ozl7VM1yN
Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host. Nature Microbiology (2019), 25th Feb. https://t.co/KcZSLLq2l4 #Batpapers #NLRP3 #Virus #inflammasome #MERSCoV #PRV3M #IAV finally..
@VirusesImmunity Great insight! I don't know much about pyroptosis, but this makes me think back to a study done on NLRP3 inflammasome in bats! Maybe explains why bats make a good reservoir for SARS-CoVs. https://t.co/7isG6YPcye
All mentions
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RT @jhas5: @tony_vandongen Take any weird immunological parts of SARS2 (e.g. NLR3P) https://t.co/0ORs5R2rSH And search for it in bat vax…
どうしてコウモリが凶悪なウイルスの感染源になっているのか。 コウモリが飛行能力を獲得する過程で、“炎症反応”を抑えてしまったからではないかという説。https://t.co/VaRmBDDhO6
RT @jhas5: @tony_vandongen Take any weird immunological parts of SARS2 (e.g. NLR3P) https://t.co/0ORs5R2rSH And search for it in bat vax…
RT @jhas5: @tony_vandongen Take any weird immunological parts of SARS2 (e.g. NLR3P) https://t.co/0ORs5R2rSH And search for it in bat vax…
@tony_vandongen Take any weird immunological parts of SARS2 (e.g. NLR3P) https://t.co/0ORs5R2rSH And search for it in bat vax literature https://t.co/LXxKH6Menm
RT @newtonnidhi: #COVID19 is a christened new virus, it is nothing but a programmed recombinant Middle East respiratory virus(MERS) & a ba…
#COVID19 is a christened new virus, it is nothing but a programmed recombinant Middle East respiratory virus(MERS) & a bat virus to mess up our cytokines cause immunity mediated damage to our own cells. Study was done in #Wuhan. https://t.co/hb3BWEFkx9
RT @DyorsMathew: 11/ What makes bats special might not be their antiviral ability, but rather their antidisease features. https://t.co/CXds…
11/ What makes bats special might not be their antiviral ability, but rather their antidisease features. https://t.co/CXds4LdLDG https://t.co/jj3nFGR0wY https://t.co/7ozl7VM1yN
@FrontImmunol Also: Dampened #NLRP3-mediated inflammation in bats and implications for a special viral reservoir host. «Our results elucidate an important mechanism through which bats dampen inflammation with implications for longevity & unique viral reservoir status.» https://t.co/7bcHE7U6sO
RT @BatResearch: @MLConradLab Amongst other things, I am a #bat #immunologist. We have shown most bat species pretty actively try and kill…
@MLConradLab Amongst other things, I am a #bat #immunologist. We have shown most bat species pretty actively try and kill the inflammasome. https://t.co/UDNXlEes98 Inspiration: @VirusesImmunity @FGinhoux @cadutertre @VirusWhisperer @IdoAmitLab @LabBroz @hornung_lab & more not on twitter!
RT @philippzross: @VirusesImmunity Great insight! I don't know much about pyroptosis, but this makes me think back to a study done on NLRP3…
@VirusesImmunity Great insight! I don't know much about pyroptosis, but this makes me think back to a study done on NLRP3 inflammasome in bats! Maybe explains why bats make a good reservoir for SARS-CoVs. https://t.co/7isG6YPcye
RT @JochenReiser: Why bats don’t care about #COVID19 Dampened NLRP3-mediated inflammation in bats and implications for a special viral res…
Why bats don’t care about #COVID19 Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host | Nature Microbiology https://t.co/psozPJYtbH
RT @dtsh2: Here's a commentary on bat tolerance to viral infections https://t.co/6paOxnjEa7 after excellent work by Ahn et al. Nat. Microbi…
RT @dtsh2: Here's a commentary on bat tolerance to viral infections https://t.co/6paOxnjEa7 after excellent work by Ahn et al. Nat. Microbi…
RT @dtsh2: Here's a commentary on bat tolerance to viral infections https://t.co/6paOxnjEa7 after excellent work by Ahn et al. Nat. Microbi…
RT @dtsh2: Here's a commentary on bat tolerance to viral infections https://t.co/6paOxnjEa7 after excellent work by Ahn et al. Nat. Microbi…
RT @dtsh2: Here's a commentary on bat tolerance to viral infections https://t.co/6paOxnjEa7 after excellent work by Ahn et al. Nat. Microbi…
RT @dtsh2: Here's a commentary on bat tolerance to viral infections https://t.co/6paOxnjEa7 after excellent work by Ahn et al. Nat. Microbi…
Here's a commentary on bat tolerance to viral infections https://t.co/6paOxnjEa7 after excellent work by Ahn et al. Nat. Microbiol. https://t.co/ipItmvX5e2
RT @BatResearch: Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host. Nature Microbiology (201…
Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host https://t.co/WVJqrKxznD
RT @BatResearch: Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host. Nature Microbiology (201…
RT @BatResearch: Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host. Nature Microbiology (201…
Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host | Nature Microbiology @NatureMicrobiol https://t.co/PfCe7rEHdJ
RT @BatResearch: Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host. Nature Microbiology (201…
RT @BatResearch: Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host. Nature Microbiology (201…
Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host. Nature Microbiology (2019), 25th Feb. https://t.co/KcZSLLq2l4 #Batpapers #NLRP3 #Virus #inflammasome #MERSCoV #PRV3M #IAV finally..
Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host https://t.co/JbKzq2Tbt5
Its out!! Still mins fresh! Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host. Congrats Star and the bat lab peeps!! :) Another revolutionary paper.