@UBC_HES Free full text here: https://t.co/CcOMbKj1SR This was a small study and secondary analyses but I think interesting and relevant. If you on LCHF and consume an occasional cheap carb “cheat” we show it may damage your endothelium... @ProfTimNoakes
Short-Term Low-Carbohydrate High-Fat Diet in Healthy Young Males Renders the Endothelium Susceptible to Hyperglycemia-Induced Damage, An Exploratory Analysis.
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Mar 2019 – Oct 2024Where it's discussed
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What people are saying
Several posts highlight concerns stemming from the study, such as 'One cheat day can actually damage your blood vessels' and 'be mindful of cheat days.' This wording reflects a serious tone and underscores the potential negative health implications associated with carbohydrate intake after following a low-carb diet. The context of the discussions elevates the perceived importance of the study, as practitioners and participants share personal anecdotes and seek expert opinions on how to adapt their diets safely while referencing the potential risks discussed in the publication.
Most discussions show a level of agreement with the study's conclusions about the potential risks of 'cheat meals' for those on low-carbohydrate diets.
There is strong interest among posters regarding the implications of the research, particularly for those following ketogenic diets.
While many posts engage with the findings and terminology from the study, some also question the sample size or share personal reflections, indicating moderate engagement.
A significant number of participants believe the findings could influence dietary choices and public perception about ketogenic diets.
Abstract in brief
- This study explored how a short-term low-carbohydrate, high-fat diet (HFD) affects the endothelial function and damage in healthy young males.
- After consuming a glucose drink, participants showed increased markers of endothelial damage and impaired function both before and after the HFD, suggesting the diet may worsen how the body handles glucose.
- Findings indicate that just a week on an HFD can make endothelial cells more susceptible to damage from high blood sugar levels, potentially raising cardiovascular disease risks.
Top posts
Most liked on X and Bluesky¡Alerta! El impacto glucémico de las cheat meal en personas que siguen una dieta Low Carb podría ser dañino para el endotelio vascular según este pequeño estudio... https://t.co/CO5O1Lc7bd Cogea bastante (pequeña muestra, corto, no ketoadaptados) pero le veo cierta lógica. https://t.co/sxn1mWSJii
"高脂肪食(糖質制限食)を若い健康人に1週間与えた臨床実験 具体的な食事内容は、脂肪が総カロリーの70%、タンパク質が20%、炭水化物が10%の構成 結果は血管が硬化し、炎症反応が高くなった" 若い健康人で血管固くなるなら、糖尿病の人がやったらどうなるんだろうか? https://t.co/w0DEmqNfJQ
Tras una semana siguiendo una dieta muy baja en hidratos de carbono, se observa un empeoramiento en la homeostasis de la glucosa tras test de tolerancia oral (75g) en hombres jóvenes. https://t.co/fCDtT13LdY https://t.co/5apVagVaV8
A very interesting study about a "cheat" meal on the keto, carnivore, or LCHF. The condition of their blood vessels after the glucose drink showed damage to the blood vessels: CVD. https://t.co/4ln9roGA7i
Be mindful of "cheat days"
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@DrStephenHussey @Michael_Buck_69 Here is research on the risk of a “cheat day meal” and layperson summary here https://t.co/mfGkrh5nHp & Paper here: https://t.co/TbqE3RCX1i
RT @MigraineBook: A very interesting study about a "cheat" meal on the keto, carnivore, or LCHF. The condition of their blood vessels after…
A very interesting study about a "cheat" meal on the keto, carnivore, or LCHF. The condition of their blood vessels after the glucose drink showed damage to the blood vessels: CVD. https://t.co/4ln9roGA7i
@themeatmedic Your endothelium must be so happy about this practice
@nicknorwitz Why would you expose yourself to increased Randle cycle and endothelial damage? Fats + carbs together is a very bad idea. https://t.co/lvfpofzbaj
@AlpacaAurelius How about the small study with alarming results once carbohydrates were reintroduced which showed blood vessel damage in all young and healthy participants. Now imagine the ones yo-yoing
@Welshinlondon @Potatothirst @DavidTestrake @SteakAndIron Small study but not the only one. https://t.co/Ps8vLJ04yZ
Nutrients | Free Full-Text | Short-Term Low-Carbohydrate High-Fat Diet in Healthy Young Males Renders the Endothelium Susceptible to Hyperglycemia-Induced Damage, An Exploratory Analysis https://t.co/xAsuVZT4Jj
@Mangan150 @DNSWilson Any concern of related to hyperglycemia-induced damage to arteries? https://t.co/Oswii1xNyH
@drdrew @VinnieTortorich https://t.co/fzryNsS6Wn Figured you could make sense of this for us fans of the vinnie diet! I think its when we break keto with high carb meals?
RT @yasu0804: "高脂肪食(糖質制限食)を若い健康人に1週間与えた臨床実験 具体的な食事内容は、脂肪が総カロリーの70%、タンパク質が20%、炭水化物が10%の構成 結果は血管が硬化し、炎症反応が高くなった" 若い健康人で血管固くなるなら、糖尿病の人がやったら…
RT @yasu0804: "高脂肪食(糖質制限食)を若い健康人に1週間与えた臨床実験 具体的な食事内容は、脂肪が総カロリーの70%、タンパク質が20%、炭水化物が10%の構成 結果は血管が硬化し、炎症反応が高くなった" 若い健康人で血管固くなるなら、糖尿病の人がやったら…
RT @yasu0804: "高脂肪食(糖質制限食)を若い健康人に1週間与えた臨床実験 具体的な食事内容は、脂肪が総カロリーの70%、タンパク質が20%、炭水化物が10%の構成 結果は血管が硬化し、炎症反応が高くなった" 若い健康人で血管固くなるなら、糖尿病の人がやったら…
"高脂肪食(糖質制限食)を若い健康人に1週間与えた臨床実験 具体的な食事内容は、脂肪が総カロリーの70%、タンパク質が20%、炭水化物が10%の構成 結果は血管が硬化し、炎症反応が高くなった" 若い健康人で血管固くなるなら、糖尿病の人がやったらどうなるんだろうか? https://t.co/w0DEmqNfJQ
@carlos_stro Hola, que opiniones tienes sobre este artículo https://t.co/A1MhT8SOSt
@ZainabSG1 @DRKAMALAYOUB https://t.co/XjQZrfXpdQ الدراسة من university of british columbia and published in nutrients.
Interesting to know for those on Keto diet. Here is a link to the full article: https://t.co/sN7CPQwa7K (thanks for sending me the link, Bill). https://t.co/QcESzbIDS7
RT @EAllen0417: Short term low CHO, high fat diet impaired flow-mediated dilation in young, healthy males. It also impaired glucose metabol…
RT @EAllen0417: Short term low CHO, high fat diet impaired flow-mediated dilation in young, healthy males. It also impaired glucose metabol…
Just a reminder to myself: "Short-Term Low-Carbohydrate High-Fat Diet in Healthy Young Males Renders the Endothelium Susceptible to Hyperglycemia-Induced Damage, An Exploratory Analysis": https://t.co/na76QM7n2r
RT @karthik2k2: Durrer et al Short-Term Low-Carbohydrate High-Fat Diet in Healthy Young Males Renders the Endothelium Susceptible to Hyperg…
Durrer et al Short-Term Low-Carbohydrate High-Fat Diet in Healthy Young Males Renders the Endothelium Susceptible to Hyperglycemia-Induced Damage, An Exploratory Analysis. Nutrients, 2019; 11 (3): 489 - On keto diet? No cheat day. Else expect damaged blood vessel.
Once you go Keto, be careful coming back. (Don’t carb blast yourself.) “Short-Term Low-Carbohydrate High-Fat Diet in Healthy Young Males Renders the Endothelium Susceptible to Hyperglycemia-Induced Damage” https://t.co/oaOFRhDpy2
VERY small study, but if you are on the Keto Diet, beware of cheat days - an extra helping of carbs can actually damage your blood vessels IF you're coming off of a high-fat, moderate protein, low carb streak! https://t.co/O2jbiFWGNo
https://t.co/4sbBlKl1EZ there's the full text of the study ... I'm reading it
@TallRedhead1014 @StickmanBleedin @Lone_Star_Keto @phil_escott @SimmonsBart @TuitNutrition Heres another bit if science to help https://t.co/mVIOSPGFMG
#mdpinutrients Short-Term Low-Carbohydrate High-Fat Diet in Healthy Young Males Renders the Endothelium Susceptible to Hyperglycemia-Induced Damage, An Exploratory Analysis https://t.co/TDmLA1Tr6F @Nutrients_MDPI
@CardiacJoshi @JuanPeirano @gfj1979 Here’s a selection: 1983 https://t.co/jsZD1AwUSh 2000 https://t.co/fn2aNnb6wo 2006 https://t.co/AGnLXHQUcX 2006 https://t.co/5wGLeFCcO6 2006 https://t.co/jLAjlrNisA 2011 https://t.co/GdyAHFtbuZ 2013 https://t.co/M9XbzvE33w 2019 https://t.co/fKfQ8zu9Zl https://t.co/3FGcZZWwpH
@tednaiman Thoughts on this study, Ted? It tells me that if one goes on a low-carb diet, they better stay on it and not cheat with junk food! https://t.co/o8UWCjpXSp
تأثير نسبة السكر في الدم على وجبة المفتوحة في الأشخاص الذين يتبعون حمية منخفضة الكربوهيدرات يمكن أن يكون ضارًا للبطانة الوعائية وفقًا لهذه الدراسة ولكن تبقى العينة في الدراسة صغيرة https://t.co/Bt1fgBIxRa https://t.co/UN4kUQfG90
RT @mitokondriac: ¡Alerta! El impacto glucémico de las cheat meal en personas que siguen una dieta Low Carb podría ser dañino para el endot…
RT @mitokondriac: ¡Alerta! El impacto glucémico de las cheat meal en personas que siguen una dieta Low Carb podría ser dañino para el endot…
¡Alerta! El impacto glucémico de las cheat meal en personas que siguen una dieta Low Carb podría ser dañino para el endotelio vascular según este pequeño estudio... https://t.co/CO5O1Lc7bd Cogea bastante (pequeña muestra, corto, no ketoadaptados) pero le veo cierta lógica. https://t.co/sxn1mWSJii
Does anyone know of any study similar to this, but involving those who are long-term keto and already fat-adapted? Would one "cheat day" really cause so much endothelial damage? https://t.co/wYgntdx2F4
7日間の高脂肪ロカボ食が耐糖能障害を引き起こし、その後の糖質摂取で血管が傷つくかも。 Short-Term Low-Carbohydrate High-Fat Diet in Healthy Young Males Renders the Endothelium Susceptible to Hyperglycemia-Induced Damage, An Explorator... - PubMed - NCBI https://t.co/qt7xZ3BNBB
@tednaiman @OKC_Biscuit @DHKiefer I'm eating
@DrEades Hey Dr. Mike... any thoughts on this study? https://t.co/Lprfm1Dl6o
@DoctorTro Apparently, a Keto diet CAN INDEED be dangerous if one cheats with carbs! https://t.co/o8UWCjpXSp
RT @CardioSix: A #keto diet may predispose the endothelium to hyperglycemia-induced damage. https://t.co/chkDUDM2cE Give #five4six to #Car…
RT @CardioSix: A #keto diet may predispose the endothelium to hyperglycemia-induced damage. https://t.co/chkDUDM2cE Give #five4six to #Car…
A #keto diet may predispose the endothelium to hyperglycemia-induced damage. https://t.co/chkDUDM2cE Give #five4six to #Cardio6 #mHealth #WearableTech #MedicalDevices #SaveLives #ketodiet
@tednaiman Sky King's Razor: If you decide to do Keto, then keep it simple. There's no room for fooling around with this diet and cheating with carbs! Apparently...
@Sadrien_GW2 @DaveKeto No, they said they were measuring actual damage markers. https://t.co/qyurNW2198 https://t.co/tayIwiO8bE
small research study found that adjustments that occur after adhering to a high fat low carb diet like the Keto diet and then having a single cheat meal high in carbs lead to a reduction in endothelial function #Biom4180 https://t.co/m4G3gbsnP8 @Nutrients_MDPI
@upyrbike @ProfTimNoakes @lowcarbGP @bschermd @DrAseemMalhotra @BrownAdey @ChristianAssad @DrScottMurray @FatEmperor @ESodicoffMD @Dr__Guess @tom_watson @PharmacistCath @KetoAnaesMD @Ad_SotoMota @FructoseNo May also affect #LCHF, although I havent read the paper, I assume ⬆️high GI carbs ⬇️glycocolayx, regardless of dietary lifestyle, make what you want from this
Interesting, exemplifies deleterious effects of high GI intakes, although haven’t read the paper
RT @DrJonLittle: @UBC_HES Free full text here: https://t.co/CcOMbKj1SR This was a small study and secondary analyses but I think interestin…
RT @DrJonLittle: @AdriaanWindt @NanciGuestRDPhD @Bigredfitness Free Full text here. Note the title: this was not designed as the definitive…
@AdriaanWindt @NanciGuestRDPhD @Bigredfitness Free Full text here. Note the title: this was not designed as the definitive test of a keto cheat day.... We show individual data and report effect sizes so I don’t think you can just say “only 9 subjects I don’t believe” Esp if you not a researcher.... https://t.co/l5y4X7ptpd
Find some Real food and balance your nutrients properly. Kick the Fad. #healthyeating #Diet #HealthyLiving #fitness https://t.co/H4U3jYsPJG
https://t.co/Xu2VVA5wO9 Low-carb diet makes blood vessels more susceptible to damage. #sciencenews https://t.co/e49X9FqHDg
@trainlikejake https://t.co/Cg4ne3dD2l
@ProfTimNoakes Endothelium Susceptible to Hyperglycemia-Induced Damage https://t.co/EPgsMPNLSe
RT @dj_surfista: Esqueça o "Dia do Lixo"! Segundo uma nova pesquisa do campus da UBC Okanagan, apenas 1 dose de carboidratos pode danificar…
https://t.co/Cg4ne3dD2l @TuitNutrition @GeorgiaEdeMD @KenDBerryMD I would very much like your assessment of this article. It’s only an n=9 on subjects on a keto diet for a short time; but...
RT @mattJstork: Be mindful of "cheat days"
Be mindful of "cheat days"
RT @RubenMurciaPrie: Tras una semana siguiendo una dieta muy baja en hidratos de carbono, se observa un empeoramiento en la homeostasis de…
Esqueça o "Dia do Lixo"! Segundo uma nova pesquisa do campus da UBC Okanagan, apenas 1 dose de carboidratos pode danificar os vasos sanguíneos. #biomarkers #lowcarb #lchf #keto #nutrition #nutrição #ketogenicdiet #cardiologia #cardiology #zerocarb https://t.co/pXjf3dP7Oq
RT @RubenMurciaPrie: Tras una semana siguiendo una dieta muy baja en hidratos de carbono, se observa un empeoramiento en la homeostasis de…
Tras una semana siguiendo una dieta muy baja en hidratos de carbono, se observa un empeoramiento en la homeostasis de la glucosa tras test de tolerancia oral (75g) en hombres jóvenes. https://t.co/fCDtT13LdY https://t.co/5apVagVaV8
RT @DrJonLittle: @UBC_HES Free full text here: https://t.co/CcOMbKj1SR This was a small study and secondary analyses but I think interestin…
RT @DrJonLittle: @UBC_HES Free full text here: https://t.co/CcOMbKj1SR This was a small study and secondary analyses but I think interestin…
RT @DrJonLittle: @UBC_HES Free full text here: https://t.co/CcOMbKj1SR This was a small study and secondary analyses but I think interestin…
RT @DrJonLittle: @UBC_HES Free full text here: https://t.co/CcOMbKj1SR This was a small study and secondary analyses but I think interestin…
RT @DrJonLittle: @UBC_HES Free full text here: https://t.co/CcOMbKj1SR This was a small study and secondary analyses but I think interestin…
RT @DrJonLittle: @UBC_HES Free full text here: https://t.co/CcOMbKj1SR This was a small study and secondary analyses but I think interestin…
RT @DrJonLittle: @UBC_HES Free full text here: https://t.co/CcOMbKj1SR This was a small study and secondary analyses but I think interestin…
RT @DrJonLittle: @UBC_HES Free full text here: https://t.co/CcOMbKj1SR This was a small study and secondary analyses but I think interestin…
RT @DrJonLittle: @UBC_HES Free full text here: https://t.co/CcOMbKj1SR This was a small study and secondary analyses but I think interestin…
RT @DrJonLittle: @UBC_HES Free full text here: https://t.co/CcOMbKj1SR This was a small study and secondary analyses but I think interestin…
RT @DrJonLittle: @UBC_HES Free full text here: https://t.co/CcOMbKj1SR This was a small study and secondary analyses but I think interestin…
RT @DrJonLittle: @UBC_HES Free full text here: https://t.co/CcOMbKj1SR This was a small study and secondary analyses but I think interestin…
RT @DrJonLittle: @UBC_HES Free full text here: https://t.co/CcOMbKj1SR This was a small study and secondary analyses but I think interestin…
@UBC_HES Free full text here: https://t.co/CcOMbKj1SR This was a small study and secondary analyses but I think interesting and relevant. If you on LCHF and consume an occasional cheap carb “cheat” we show it may damage your endothelium... @ProfTimNoakes
RT @Karageorgos15: @ChristianAssad Or possibly worse if have more regular cheat days/cycling with processed carbs/foods: https://t.co/uqz3m…
@ChristianAssad Or possibly worse if have more regular cheat days/cycling with processed carbs/foods: https://t.co/uqz3mPZ9OV https://t.co/pEbw5wosS0
A high-carb meal after a high-fat diet may damage the endotherlium (open access) https://t.co/PczU3kybpo #nutrition #diet
"These new findings suggest that if young, healthy males are following such (LCHF) diets, a temporary lapse in adherence with consumption of a food causing a glucose spike might lead to acute endothelial damage." https://t.co/JGweCvwpXM