May 2019 PMID 30831541

Effects of melatonin administration on mental health parameters, metabolic and genetic profiles in women with polycystic ovary syndrome: A randomized, double-blind, placebo-controlled trial.

Azade Shabani, Fatemeh Foroozanfard, Elham Kavossian, Esmat Aghadavod, Vahidreza Ostadmohammadi, Russel J Reiter, Tahereh Eftekhar, Zatollah Asemi

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Mentions

6
Peak: 2 in Mar 2019
across 3 sources since Mar 2019

Extended reach

194,519
potential audience

Total likes

4,218

Video views

187,127

Mentions per month

Mar 2019 – Jul 2025

Where it's discussed

  • X / Twitter2 posts
  • YouTube2 videos
  • Facebook2 posts

AI synopsis

What people are saying

The analysis reveals a generally neutral stance with limited enthusiasm, as seen in the repetitive mentions of the study's title without elaboration or critical discussion. Phrases like 'Effects of melatonin' and citations of the author and journal indicate recognition but lack concrete discussion or interpretation, reflecting minimal engagement and impact.

AgreementNeither agree nor disagree

The discussion appears neutral with no strong supportive or opposing sentiments expressed toward the publication.

InterestModerate interest

Participants show mild interest, possibly due to repeated mentions of the article's title without detailed commentary.

EngagementNeutral engagement

There is minimal in-depth analysis or critical engagement with the research, indicated by the generic references.

ImpactNeutral impact

The posts do not suggest the publication has significantly influenced opinions or practices beyond basic acknowledgment.

Abstract in brief

  • The study shows that melatonin supplementation in women with polycystic ovary syndrome (PCOS) for 12 weeks improves mental health by reducing depression and anxiety, and enhances sleep quality.
  • It also positively impacts metabolic parameters by lowering serum insulin, insulin resistance (HOMA-IR), total cholesterol, and LDL levels, while increasing insulin sensitivity (QUICKI).
  • Additionally, melatonin influences genetic expression related to metabolism, notably increasing the activity of genes involved in insulin and lipid regulation, such as PPAR gamma and LDL receptor.]

Top posts

Most liked on X and Bluesky
Sleep Research
@SleepResearch_ · X

Effects of melatonin administration on mental health parameters, metabolic and genetic profiles in women with polycystic ovary syndrome: A randomized, double-blind, placebo-controlled trial. https://t.co/AbcJnt8faa

Mar 5, 2019 · 7,257 followers View post →
the paper link
@the_paper_link · X

[trend] up+1: *Shabani A* et al (J Affect Disord) **Effects of melatonin administration on mental health parameters, metabolic and genetic profiles in women with polycystic ovary syndrome: A randomized, double-blind, placebo-controlled trial.** https://t.co/HoI37gQDCC

Mar 7, 2019 · 136 followers View post →

All mentions

the paper link
@the_paper_link · X

[trend] up+1: *Shabani A* et al (J Affect Disord) **Effects of melatonin administration on mental health parameters, metabolic and genetic profiles in women with polycystic ovary syndrome: A randomized, double-blind, placebo-controlled trial.** https://t.co/HoI37gQDCC

Mar 7, 2019 · 136 followers View post →
Sleep Research
@SleepResearch_ · X

Effects of melatonin administration on mental health parameters, metabolic and genetic profiles in women with polycystic ovary syndrome: A randomized, double-blind, placebo-controlled trial. https://t.co/AbcJnt8faa

Mar 5, 2019 · 7,257 followers View post →