Stem Cells Transl Med June 2019 PMID 30835956

Intra-Articular Injection of Autologous Adipose Tissue-Derived Mesenchymal Stem Cells for the Treatment of Knee Osteoarthritis: A Phase IIb, Randomized, Placebo-Controlled Clinical Trial.

Woo-Suk Lee, Hwan Jin Kim, Kang-Il Kim, Gi Beom Kim, Wook Jin

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Mentions

Peak: 6 in Aug 2023

across 5 sources since Mar 2019

Extended reach

42,803

potential audience

Total likes

Video views

162

Mentions per month

Mar 2019 – Aug 2024

Where it's discussed

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News4 articles
Facebook3 posts
Blogs3 articles
YouTube2 videos

AI synopsis

What people are saying

The discussions demonstrate a generally positive perception, with many posters emphasizing improvements in joint function and pain relief, as seen in statements like 'injecting mesenchymal stem cells results in functional improvement' and references to ongoing studies and treatments. The tone is optimistic and familiar, reflecting a shared interest in the therapeutic promise of stem cells for osteoarthritis.

AgreementModerate agreement

Most discussions reflect support and acknowledgment of the positive findings and potential of mesenchymal stem cells for knee osteoarthritis.

InterestModerate interest

Posts show moderate curiosity, referencing the article's results and related technologies, but lack deep technical analysis.

EngagementModerate engagement

Comments include mentions of specific studies, treatment options, and event promotions, indicating some involvement but not deep scientific critique.

ImpactModerate impact

Several posts highlight the significance of the research findings and suggest practical applications, implying a moderate influence on attitudes and potential practice.

Abstract in brief

This phase IIb clinical trial investigated the safety and effectiveness of injecting a patient's own fat-derived mesenchymal stem cells (ADMSCs) directly into the knee joint to treat osteoarthritis, showing significant improvement in joint function and pain relief after 6 months compared to a placebo.
The study found that while the stem cell treatment improved symptoms and maintained cartilage, there was no significant change in cartilage damage as seen on MRI, and no serious side effects occurred during the follow-up period.
Overall, a single injection of autologous ADMSCs appears safe and beneficial for knee osteoarthritis, but larger studies and longer-term data are needed to confirm these findings.]

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