March 2019 PMID 30871577

Urolithin A attenuates memory impairment and neuroinflammation in APP/PS1 mice.

Zhuo Gong, Jingyi Huang, Biao Xu, Zhenri Ou, Le Zhang, Xiaohong Lin, Xiujuan Ye, Xuejian Kong, Dahong Long, Xiangdong Sun, Xiaosong He, Liping Xu, Qingqing Li, Aiguo Xuan

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Mentions

Peak: 10 in Nov 2024

across 4 sources since Oct 2019

Extended reach

1,126,147

potential audience

Total likes

23,193

Video views

1,043,585

Mentions per month

Oct 2019 – Dec 2025

Where it's discussed

X / Twitter25 posts
YouTube6 videos
Facebook3 posts
News3 articles

AI synopsis

What people are saying

The collective discussions show a positive outlook towards Urolithin A, with posts emphasizing its potential for brain health and longevity, using words like 'discover' and 'protects,' which convey curiosity and optimism. Some examples include references to mechanisms such as autophagy and inflammation reduction, demonstrating moderate engagement with the research details. The tone suggests that users see this as an impactful development in neurodegenerative disease research.

AgreementModerate agreement

Most discussions highlight positive effects of Urolithin A and reference the study's findings, indicating general agreement.

InterestHigh interest

The posts show high curiosity with mentions of neuroprotection, autophagy, and potential health benefits, reflecting strong interest.

EngagementModerate engagement

Several discussions cite specific mechanisms like reducing inflammation and promoting neurogenesis, demonstrating moderate engagement.

ImpactModerate impact

The enthusiastic tone and references to Urolithin A as a 'fountain of youth' or significant neuroprotective agent suggest perceived meaningful impact.

Abstract in brief

Urolithin A (UA) can improve memory and reduce brain inflammation in a mouse model of Alzheimer's disease (AD) by protecting neurons from death, reducing harmful protein deposits, and promoting new neuron growth.
UA works by activating specific brain cell signaling pathways, such as increasing AMPK activity and decreasing inflammatory pathways like P65-NF-κB and P38 MAPK, which helps lessen neuroinflammation and amyloid plaque formation.
These findings suggest that UA, a natural metabolite, has potential as a therapeutic agent for AD because it can protect brain cells, reduce inflammation, and improve cognitive function in affected mice.

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All mentions

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Urolithin A enhances memory and reduces brain inflammation by protecting neurons and decreasing harmful protein deposits, promoting new neuron growth in Alzheimer’s disease models.

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Dr. Suzana Mantovani

@Tweet_Nutrition · X

Got Inflammation? Discover Urolithin A https://t.co/LBSr7Z86zL via @YouTube

May 11, 2025 · 4,584 followers View post →

StereoMatch

@stereomatch2 · X

Apr 7, 2025 · 1 like · 746 followers View post →

Extreme MAGA P01135809

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@toobaffled Got Inflammation? Discover Urolithin A - Drbeen Medical Lectures https://t.co/cDli6t0nPI

Jan 8, 2025 · 1,628 followers View post →

Extreme MAGA P01135809

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@loosetwit @myhiddenvalue @IanCarrollShow Got Inflammation? Discover Urolithin A - Drbeen Medical Lectures https://t.co/cDli6t0VFg

Jan 6, 2025 · 1,628 followers View post →

jeff black

@jeffblack757 · X

RT @drbeen_medical: The Fountain of Youth in Your Gut? Discover Urolithin A https://t.co/NPlSILAj8X via @YouTube

Dec 18, 2024 · 4 shares · 4,382 followers View post →

Thomas Anthony III

@MeasslainteIRL · X

RT @drbeen_medical: The Fountain of Youth in Your Gut? Discover Urolithin A https://t.co/NPlSILAj8X via @YouTube

Dec 18, 2024 · 4 shares · 4,771 followers View post →

Free56

@Free5620 · X

https://t.co/tx4IcVO7PP

Nov 11, 2024 · 198 followers View post →

Thomas Anthony III

@MeasslainteIRL · X

@harryetaylor Hi Harry , how many boosters have you had ? Got Chronic Inflammation? Discover Urolithin A #Pomegranate #autophagy #DNArepair #mTOR #inflammation https://t.co/q2FTZjWUVu

Nov 9, 2024 · 4,771 followers View post →

Barbara C. Hickman

@_bhickman · X

The Fountain of Youth in Your Gut? Discover Urolithin A Drbeen Medical Lectures https://t.co/fIeceWh704

Nov 8, 2024 · 1,398 followers View post →

Jimmy_S01E07

@Jimmy_S01E07 · X

RT @drbeen_medical: The Fountain of Youth in Your Gut? Discover Urolithin A https://t.co/NPlSILAj8X via @YouTube

Nov 7, 2024 · 4 shares · 53 followers View post →

Ninnis Tankar

@Ninnis_tankar · X

RT @drbeen_medical: The Fountain of Youth in Your Gut? Discover Urolithin A https://t.co/NPlSILAj8X via @YouTube

Nov 7, 2024 · 4 shares · 7,327 followers View post →

Dr. Mobeen Syed

@drbeen_medical · X

The Fountain of Youth in Your Gut? Discover Urolithin A https://t.co/NPlSILAj8X via @YouTube

Nov 7, 2024 · 10 likes · 4 shares · 33,128 followers View post →

Tracy

@xxtracy09xx · X

RT @xxtracy09xx: The Fountain of Youth in Your Gut? Discover Urolithin A https://t.co/OWQOyCwzHw via @YouTube

Nov 7, 2024 · 1 share · 1,180 followers View post →

Robustiana

@btc_freedom · X

The Fountain of Youth in Your Gut? Discover Urolithin A https://t.co/jIT439WON1 a través de @YouTube

Nov 7, 2024 · 1 like · 734 followers View post →

Tracy

@xxtracy09xx · X

The Fountain of Youth in Your Gut? Discover Urolithin A https://t.co/OWQOyCwzHw via @YouTube

Nov 7, 2024 · 1 like · 1 share · 1,180 followers View post →

blubber_bones

@blubber_bones · X

4 Studies Find the #1 Diet for Humans (Not Carnivore OR Vegan) https://t.co/4AGYhRQhJj via @YouTube

Oct 3, 2023 · 1,075 followers View post →

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@de_bose · X

Apr 8, 2023 · 2 likes · 2,180 followers View post →

Kieran Volz | Fitness

@kickflipcoder · X

Say WWWWHHHHHAAAATTTTTT??? This Fruit BLOCKS Alcohol from Damaging the Brain (and other neurotoxins) https://t.co/Ehd7hQRKWT via @YouTube

Sep 8, 2022 · 330 followers View post →

Nightgammer

@Nitegammer_ · X

https://t.co/S95cI2NCFt

Aug 29, 2022 · 1,492 followers View post →

Lori Morse

@Lmsavy60 · X

This Fruit Protects the Brain from Alcohol (and Stress Damage) https://t.co/IeAPr0sUus via @YouTube

Aug 29, 2022 · 494 followers View post →

Cheo (Chāy Ō)

@CheoWalker · X

Thomas DeLauer This Fruit Protects the Brain from Alcohol (and Stress Damage) https://t.co/qiDFJzBsRX #keto

Aug 29, 2022 · 350 followers View post →

dominique renucci

@yogayantra · X

1/2 Cup of This FRUIT Increases AUTOPHAGY (longevity benefits) https://t.co/47Yk70cnPT via @YouTube

Jul 19, 2022 · 1,006 followers View post →

Cheo (Chāy Ō)

@CheoWalker · X

Thomas DeLauer Do NOT Eat THIS FRUIT for Longevity (there’s a serious catch) https://t.co/7SwOVvip0w #keto

Jul 18, 2022 · 350 followers View post →

TACT

@TactNowInfo · X

Apr 12, 2022 · 4 likes · 7,415 followers View post →

Rich Hartman

@HartmanNeuroLab · X

We were just cited in this paper - Urolithin A attenuates memory impairment and neuroinflammation in APP/PS1 mice https://t.co/lnkyr8ovYp

Oct 27, 2019 · 120 followers View post →

Urolithin A attenuates memory impairment and neuroinflammation in APP/PS1 mice.

Mentions per month

Where it's discussed

What people are saying

Abstract in brief

Top posts

All mentions

The Return of Keto: Insights and Learnings from 5 Years of Experience

Optimal Human Diet Based on Scientific Studies and Neuroinflammation Research

Pomegranate Fruit Increases Autophagy and Supports Brain Health

Urolithin A Protects Brain Cells and Improves Memory in Alzheimer's Model

Urolithin A: A Key to Combating Inflammation and Alzheimer's Disease

Urolithin A's Role in Reducing Inflammation and Enhancing Cell Health

Latest Insights into the 2023 Ketogenic Diet and Its Benefits