J Neuroinflammation March 2019 PMID 30885223

Expansion and activation of distinct central memory T lymphocyte subsets in complex regional pain syndrome.

Marc A Russo, Nathan T Fiore, Caryn van Vreden, Dominic Bailey, Danielle M Santarelli, Helen M McGuire, Barbara Fazekas de St Groth, Paul J Austin

Mentions

23
Peak: 10 in Mar 2019
across 3 sources since Mar 2019

Extended reach

36,176
potential audience

Total likes

83

Video views

1,212

Mentions per month

Mar 2019 – Feb 2021

Where it's discussed

  • X / Twitter16 posts
  • YouTube4 videos
  • Facebook3 posts

AI synopsis

What people are saying

The discussions reflect strong interest and engagement, with posts praising the research as 'ground-breaking' and 'amazing,' citing specific immune response details like T lymphocyte activation. Words like 'pave the way' and 'help improve understanding' highlight perceivable impact, while references to 'immune cell profile' and 'personalized immunotherapy' suggest potential for significant advances in CRPS treatment strategies.

AgreementModerate agreement

Most posts acknowledge the significance of the research, emphasizing its contribution to understanding CRPS as an immune-related condition.

InterestHigh interest

Discussions show high interest, with many posts highlighting the novelty and importance of immune responses in CRPS.

EngagementHigh engagement

Posts actively interpret the findings, referencing specific immune cell types and potential clinical implications, demonstrating deep engagement.

ImpactModerate impact

Several posts suggest that this research could influence future treatments, indicating a moderate to high potential impact.

Abstract in brief

  • This study investigates how different central memory T lymphocyte subsets are expanded and activated in patients with complex regional pain syndrome (CRPS), a chronic pain condition that may involve immune responses, particularly autoantibodies.
  • Using mass cytometry to analyze blood samples from CRPS patients and healthy controls, the research reveals significant increases in specific T cell populations (e.g., CD8 central memory, Th1, Treg cells) along with their heightened activation markers, suggesting an immune component in CRPS.
  • The findings also show alterations in dendritic cells, such as decreased numbers but increased activation signals, indicating possible immune cell trafficking and activation processes that could contribute to the disease's pathology.]

Top posts

Most liked on X and Bluesky
Dr Marc Russo
@DrMarcRusso · X

Ground-breaking CRPS research by Drs Russo & Austin identifying a unique immune cell profile in the serum of CRPS patients. This may pave the way to personalised immunotherapy treatments. To read more https://t.co/6f70MDYtfE #GenesisResearch #SydneyUniversity #HunterPain

Mar 21, 2019 · 34 likes · 17 shares · 763 followers View post →
Dr Humble - Clinical Skincare | Aesthetics
@drhumbleskin · X

New research helping to improve the scientific understanding of CRPS

Mar 22, 2019 · 13 likes · 3 shares · 1,183 followers View post →
CRPS Warrior
@CRPS_RSD_UNITED · X

Amazing piece of CRPS research by Dr Marc Russo, Dr Austin et al (2019) identifying a unique immune cell profile in the serum of CRPS patients. According to Drs Russo & Austin this may pave the... https://t.co/9jamEaUWHx

Mar 22, 2019 · 1 like · 1 share · 2,416 followers View post →
Nancy Garcia ✍️
@GarciaNancy · X

For those of you interested in molecular biology and medical diagnoses & treatment (@emilykatehayes): https://t.co/8Uxl9lOGOG reports prelim data of chronic antigen-mediated T lymphocyte response in the challenging, perplexing condition complex regional pain syndrome

Mar 21, 2019 · 1 like · 373 followers View post →
Burning Nights CRPS
@BNightsCRPS · X

RT @kafkesque787: New research helping to improve the scientific understanding of CRPS

Mar 22, 2019 · 3 shares · 10,653 followers View post →
Suzanne Shoker
@SuzanneShoker1 · X

RT @FibroFlutters: Expansion and activation of distinct central memory T lymphocyte subsets in complex regional pain syndrome https://t.co/…

Mar 31, 2019 · 1 share · 5,219 followers View post →

All mentions

MD_PhD in Japan
@japan_phd · X

Expansion and activation of distinct central memory T lymphocyte subsets in complex regional pain syndrome | Journal of Neuroinflammation | Full Text https://t.co/nIBCjf5dvb

Feb 8, 2021 · 295 followers View post →
Power Beyond Psoriasis
@Psoriasischamp · X

RT @SandraWoodsMtl: 2019: #CRPS "is a debilitating condition... results in devastating persistent #pain" ⤵️ "accumulating evidence suggests…

Feb 10, 2020 · 1 share · 2,546 followers View post →
Sandra Woods, CIPP/C; she/her
@SandraWoodsMtl · X

2019: #CRPS "is a debilitating condition... results in devastating persistent #pain" ⤵️ "accumulating evidence suggests it is an immunoneurological disorder" ↔️ "an antigen-mediated T lymphocyte response" #chronicpain https://t.co/i4P4NUtFBP

Feb 10, 2020 · 1 share · 2,025 followers View post →
ProActive Pain Care
@ProActivepainca · X

Expansion and activation of distinct central memory T lymphocyte subsets in complex regional pain sy #backpain https://t.co/f8kBRq97Ip

Apr 30, 2019 · 4 followers View post →
ProActive Pain Care
@ProActivepainca · X

Expansion and activation of distinct central memory T lymphocyte subsets in complex regional pain sy #backpain https://t.co/f8kBRq97Ip

Apr 29, 2019 · 4 followers View post →
Paradise in the Woods
@JesupRanch · X

RT @CRPS_RSD_UNITED: Amazing piece of CRPS research by Dr Marc Russo, Dr Austin et al (2019) identifying a unique immune cell profile in th…

Apr 6, 2019 · 1 share · 80 followers View post →
Suzanne Shoker
@SuzanneShoker1 · X

RT @FibroFlutters: Expansion and activation of distinct central memory T lymphocyte subsets in complex regional pain syndrome https://t.co/…

Mar 31, 2019 · 1 share · 5,219 followers View post →
Flutters and Strutters (Formerly FibroFlutters)
@FibroFlutters · X

Expansion and activation of distinct central memory T lymphocyte subsets in complex regional pain syndrome https://t.co/prkLLtgn8a

Mar 30, 2019 · 1 share · 3,472 followers View post →
Carole Sian
@scrufton73 · X

Expansion and activation of distinct central memory T lymphocyte subsets in complex regional pain syndrome https://t.co/AFnvltwuh5

Mar 30, 2019 · 2,004 followers View post →
Vijay
@vijayanandnz · X

RT @kafkesque787: New research helping to improve the scientific understanding of CRPS

Mar 23, 2019 · 3 shares · 3,310 followers View post →
CRPS Warrior
@CRPS_RSD_UNITED · X

Amazing piece of CRPS research by Dr Marc Russo, Dr Austin et al (2019) identifying a unique immune cell profile in the serum of CRPS patients. According to Drs Russo & Austin this may pave the... https://t.co/9jamEaUWHx

Mar 22, 2019 · 1 like · 1 share · 2,416 followers View post →
Burning Nights CRPS
@BNightsCRPS · X

RT @kafkesque787: New research helping to improve the scientific understanding of CRPS

Mar 22, 2019 · 3 shares · 10,653 followers View post →
Dr Humble - Clinical Skincare | Aesthetics
@drhumbleskin · X

New research helping to improve the scientific understanding of CRPS

Mar 22, 2019 · 13 likes · 3 shares · 1,183 followers View post →
Nancy Garcia ✍️
@GarciaNancy · X

For those of you interested in molecular biology and medical diagnoses & treatment (@emilykatehayes): https://t.co/8Uxl9lOGOG reports prelim data of chronic antigen-mediated T lymphocyte response in the challenging, perplexing condition complex regional pain syndrome

Mar 21, 2019 · 1 like · 373 followers View post →
Cytof Manchester
@ManchesterCytof · X

Expansion and activation of distinct central memory T lymphocyte subsets in complex regional pain syndrome | Journal of Neuroinflammation #cytofpub https://t.co/McqELB2Sb1

Mar 21, 2019 · 554 followers View post →
Dr Marc Russo
@DrMarcRusso · X

Ground-breaking CRPS research by Drs Russo & Austin identifying a unique immune cell profile in the serum of CRPS patients. This may pave the way to personalised immunotherapy treatments. To read more https://t.co/6f70MDYtfE #GenesisResearch #SydneyUniversity #HunterPain

Mar 21, 2019 · 34 likes · 17 shares · 763 followers View post →