Most discussions involve critical reflections on the research's findings, such as mentions of the high false positive rate (~16%) and concerns over unnecessary invasive procedures, demonstrating skepticism and cautious interest. The tone varies from clinical critique to moral concern, guiding the overall moderate engagement and uncertain consensus about the impact of these findings.
AgreementLow agreement
Many discussions highlight the limitations and potential harms of whole-body MRI screening, showing skepticism and concern, but some also recognize its potential diagnostic value without full endorsement.
InterestNeutral interest
The overall interest appears moderate, with some participants referencing the importance of the research and expressing opinions, but few engaging deeply or seeking more information.
EngagementModerate engagement
There is some thoughtful critique and debate, especially around false positives and ethical concerns, indicating moderate engagement but not deeply technical or personal involvement.
ImpactNeutral impact
The discussions seem to influence opinions about the utility and dangers of widespread screening, but the overall consensus and direct impact on policy or practice remain limited.
Abstract in brief
The systematic review examined how often wholebody MRI scans in healthy, asymptomatic adults reveal critical or uncertain incidental findings, analyzing data from 12 studies with over 5,300 participants.
The overall prevalence of these incidental findings was about 32%, with higher rates (about 50%) in studies that included cardiovascular or colon MRI scans.
The review highlights that a significant portion of findings are false positives (around 16%), and there’s limited information on long-term verification of negative results or the accuracy of negative findings.
that’s not “from” the NIH; PubMed indexes papers in scientific journals and sometimes (eg certain public funding) also co-posts the full text publicly in PubMed Central
(this article is published in the Journal of MRI)
@VPrasadMDMPH Full body scans have even more problems:
https://t.co/CMWueMfkl1
1. False positives
2. Irrelevant true positives - as you eloquently clarify above
3. False attribution of symptoms to "abnormal" findings, leading to missed diagnoses
4. Static images
@nealkhosla @chrissyfarr The issue is Brandolini's law - prenuvo and other companies prey on patients with a story that sounds good but is scientifically nonsense if you dig deeper.
I go into all the reasons why these scans are scientifically unsound in my video here:
https://t.co/CMWueMfkl1
@extuhzee We find them to be a very useful advanced cancer diagnostic tool
The downsides are:
- Cost ($2500, insurances do not cover)
- High false positive rate (~16%) - https://t.co/7goRA21WRd
@ezrainc @Biograph are good companies that offer them in addition to @prenuvo
Mar 27, 2025 · 3 likes · 1 share · 75 followersView post →
DM
Dr. Zain | RiverRock Medical
@DrZainHakeem · X
@chrissyfarr Hey, I'm a physician with a unique take on healthcare, with a private practice. I did a pretty intense takedown of that full body MRI nonsense, here's a link if you're interested. Love to discuss further.
https://t.co/CMWueMfkl1
Full body MRI scans are promoted as early disease detection tools, but they pose challenges such as false positives and misinterpretation of test mathematics. This video explores the limitations and potential harms of…
Doctors often warn against full-body MRI due to incidental findings. This review examines their prevalence, accuracy, and the implications for preventive health, questioning whether these warnings are justified based on…
@astrodanish There has been some research looking at the value of screening MRIs and what people find is that there’s a substantial amount of incidental findings/false positives that require even more invasive workup, making it not really worth it. https://t.co/piWhQ9mErM
that’s not “from” the NIH; PubMed indexes papers in scientific journals and sometimes (eg certain public funding) also co-posts the full text publicly in PubMed Central
(this article is published in the Journal of MRI)
RT @vitavedahealth: @extuhzee We find them to be a very useful advanced cancer diagnostic tool
The downsides are:
- Cost ($2500, insurance…
Mar 27, 2025 · 1 share · 5,183 followersView post →
VL
Vita Veda Longevity
@vitavedahealth · X
@extuhzee We find them to be a very useful advanced cancer diagnostic tool
The downsides are:
- Cost ($2500, insurances do not cover)
- High false positive rate (~16%) - https://t.co/7goRA21WRd
@ezrainc @Biograph are good companies that offer them in addition to @prenuvo
Mar 27, 2025 · 3 likes · 1 share · 75 followersView post →
DM
Dr. Zain | RiverRock Medical
@DrZainHakeem · X
@nealkhosla is a great example of how companies like @prenuvo can fool people by spinning a story that "makes sense" (that's what con artists do), but only on deeper consideration can you see the inherent flaws.
4 Problems with full-body scans:
https://t.co/CMWueMfSaz
@VPrasadMDMPH Full body scans have even more problems:
https://t.co/CMWueMfkl1
1. False positives
2. Irrelevant true positives - as you eloquently clarify above
3. False attribution of symptoms to "abnormal" findings, leading to missed diagnoses
4. Static images
@nealkhosla @chrissyfarr The issue is Brandolini's law - prenuvo and other companies prey on patients with a story that sounds good but is scientifically nonsense if you dig deeper.
I go into all the reasons why these scans are scientifically unsound in my video here:
https://t.co/CMWueMfkl1
@chrissyfarr Hey, I'm a physician with a unique take on healthcare, with a private practice. I did a pretty intense takedown of that full body MRI nonsense, here's a link if you're interested. Love to discuss further.
https://t.co/CMWueMfkl1
@Mangan150 I also referenced this study in my video on full-body MRIs, and the rampant misunderstanding of this math by people like @PeterAttiaMD and @davidasinclair, let alone the lay public and influencers like @KimKardashian.
https://t.co/n6hUSMZqZw
@XavierHelgesen @EricPoortinga @cmwilliams99 it’s tortured logic to use anecdotes as a replacement of data. False positive rate 16%, false neg rate 2%. No evidence it saves lives https://t.co/vmuxAFDFSl
Aug 14, 2022 · 1 like · 4,327 followersView post →
S
SystematicReviewBot
@EvidenceRobot · X
RT @researchumcg: Whole-body MRI for preventive health screening: A systematic review of the literature https://t.co/zCRpmqxJpN
Oct 30, 2019 · 1 share · 6,685 followersView post →
RU
Research UMCG
@researchumcg · X
Whole-body MRI for preventive health screening: A systematic review of the literature https://t.co/zCRpmqxJpN
Oct 30, 2019 · 1 share · 2,631 followersView post →
S
SystematicReviewBot
@EvidenceRobot · X
RT @researchumcg: New Open Access: Whole-body MRI for preventive health screening: A systematic review of the literature https://t.co/zCRpm…
Oct 30, 2019 · 1 share · 6,685 followersView post →
RU
Research UMCG
@researchumcg · X
New Open Access: Whole-body MRI for preventive health screening: A systematic review of the literature https://t.co/zCRpmqxJpN
Oct 30, 2019 · 1 share · 2,631 followersView post →
N
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News
doi:10.1002/jmri.26736. Petralia G, Zugni F, Summers PE, et al. Whole-body magnetic resonance imaging (WB-MRI) for cancer screening ...