Phytother Res May 2019 PMID 30968986

A double-blind, randomized, placebo-controlled study to assess the efficacy of Andrographis paniculata standardized extract (ParActin®) on pain reduction in subjects with knee osteoarthritis.

Juan L Hancke, Shalini Srivastav, Dante D Cáceres, Rafael A Burgos

Mentions

31
Peak: 13 in Mar 2024
across 5 sources since Apr 2019

Extended reach

116,417
potential audience

Total likes

205

Video views

9,863

Mentions per month

Apr 2019 – May 2025

Where it's discussed

  • X / Twitter18 posts
  • Facebook6 posts
  • News3 articles
  • Bluesky2 posts
  • YouTube2 videos

AI synopsis

What people are saying

The discussions reflect a mix of cautious support and skepticism, with some posts calling the research 'effective against osteoarthritis' and others making dismissive or humorous remarks like 'stupidness of the patients,' which dilute the overall perceived seriousness. The tone varies from clinical acknowledgment to sarcasm, influencing the overall neutral score across the dimensions.

AgreementNeither agree nor disagree

Most discussions acknowledge the study's findings but are mixed in enthusiasm, with some skepticism and some support for the reported benefits.

InterestModerate interest

The discussions show moderate interest, especially among those in healthcare or research, but also include dismissive remarks and unrelated comments.

EngagementNeutral engagement

Participants mostly mention the study briefly or in passing, with few in-depth analyses or detailed discussions, indicating moderate engagement.

ImpactModerate impact

The conversation seems to recognize the study's relevance but does not reflect a widespread perception of profound impact, more like cautious interest.

Abstract in brief

  • This study tested the effectiveness of ParActin, a supplement made from Andrographis paniculata, in reducing knee pain associated with osteoarthritis, using a double-blind placebo-controlled design.
  • Results showed that patients taking either 300mg or 600mg of ParActin daily experienced significant decreases in pain, joint stiffness, and physical function issues over 84 days, along with improvements in quality of life and fatigue scores.
  • The findings suggest that ParActin at both dosages is safe and effective for alleviating pain and improving life quality in people with mild to moderate knee osteoarthritis.]

Top posts

Most liked on X and Bluesky
Kabuto
@DrStarWolf · X

@NuclearYoshi @vonbateman Scepticism leads to septic choc :A double blind randomized placebo-controlled study to assess the stupidness of the patients New English journal of Moron

Mar 2, 2021 · 4 likes · 8,255 followers View post →
Biogrow
@biogrow.bsky.social · Bluesky

Study of 100 participants / 26 weeks. Half received yeast beta-glucan and half received a placebo. Source: Graubaum et al., Food and Nutrition Sciences (2012) - A Double-Blind, Randomized, Placebo-Controlled Study on Beta-Glucan

May 13, 2025 · 2 likes View post →
Andrew Waye, PhD
@cannabis-scientist.bsky.social · Bluesky

A double-blind, randomized, placebo-controlled study of the safety and effects of CBN with and without CBD on sleep quality pubmed.ncbi.nlm.nih.gov/37796540/

Oct 19, 2023 · 2 likes · 2 shares View post →
Dr Mitchell low
@DrMitchLow · X

Knee osteoarthritis pain? Try Andrographis paniculata. A new double‐blind, randomised, placebo‐controlled study has assessed the efficacy of Andrographis paniculata extract on pain reduction in subjects with #knee #osteoarthritis. # inflammation https://t.co/zL4lOPQyXV

Apr 16, 2019 · 1 like · 1 share · 101 followers View post →
abdul ghani qiq
@cintaforex · X

https://t.co/fuiKwPnEO1

Jul 25, 2021 · 75,427 followers View post →
EurekaMag
@EurekaMag · X

A double-blind, randomized, placebo-controlled study to assess the safety, antiviral activity and pharmacokinetics of GSK2336805 when given as monotherapy and in combination with peginterferon alfa-2a https://t.co/2stAJer4Re https://t.co/FM4IbJeqLT

Mar 20, 2024 · 7 shares · 6,542 followers View post →

All mentions

Biogrow
@biogrow.bsky.social · Bluesky

Study of 100 participants / 26 weeks. Half received yeast beta-glucan and half received a placebo. Source: Graubaum et al., Food and Nutrition Sciences (2012) - A Double-Blind, Randomized, Placebo-Controlled Study on Beta-Glucan

May 13, 2025 · 2 likes View post →
Science Alerts
@Science_Alerts · X

RT @EurekaMag: A double-blind, randomized, placebo-controlled study to assess the safety, antiviral activity and pharmacokinetics of GSK233…

Mar 20, 2024 · 7 shares · 1,234 followers View post →
amnatacharoen
@amnatacharoen · X

RT @EurekaMag: A double-blind, randomized, placebo-controlled study to assess the safety, antiviral activity and pharmacokinetics of GSK233…

Mar 20, 2024 · 7 shares · 4 followers View post →
Science Index
@ScienceIndex_ · X

RT @EurekaMag: A double-blind, randomized, placebo-controlled study to assess the safety, antiviral activity and pharmacokinetics of GSK233…

Mar 20, 2024 · 7 shares · 1,010 followers View post →
POPLINE
@POPLINE_org · X

RT @EurekaMag: A double-blind, randomized, placebo-controlled study to assess the safety, antiviral activity and pharmacokinetics of GSK233…

Mar 20, 2024 · 7 shares · 5,238 followers View post →
GeoScience.net
@GeoSciences · X

RT @EurekaMag: A double-blind, randomized, placebo-controlled study to assess the safety, antiviral activity and pharmacokinetics of GSK233…

Mar 20, 2024 · 7 shares · 404 followers View post →
songdaon
@songdaon · X

RT @EurekaMag: A double-blind, randomized, placebo-controlled study to assess the safety, antiviral activity and pharmacokinetics of GSK233…

Mar 20, 2024 · 7 shares · 19 followers View post →
Scien.net
@Scien_net · X

RT @EurekaMag: A double-blind, randomized, placebo-controlled study to assess the safety, antiviral activity and pharmacokinetics of GSK233…

Mar 20, 2024 · 7 shares · 65 followers View post →
Scien.net
@Scien_net · X

RT @popline_org: A double-blind, randomized, placebo-controlled study to assess the safety, antiviral activity and pharmacokinetics of GSK2…

Mar 20, 2024 · 4 shares · 65 followers View post →
Science Alerts
@Science_Alerts · X

RT @popline_org: A double-blind, randomized, placebo-controlled study to assess the safety, antiviral activity and pharmacokinetics of GSK2…

Mar 20, 2024 · 4 shares · 1,234 followers View post →
Science Index
@ScienceIndex_ · X

RT @popline_org: A double-blind, randomized, placebo-controlled study to assess the safety, antiviral activity and pharmacokinetics of GSK2…

Mar 20, 2024 · 4 shares · 1,010 followers View post →
songdaon
@songdaon · X

RT @popline_org: A double-blind, randomized, placebo-controlled study to assess the safety, antiviral activity and pharmacokinetics of GSK2…

Mar 20, 2024 · 4 shares · 19 followers View post →
POPLINE
@POPLINE_org · X

A double-blind, randomized, placebo-controlled study to assess the safety, antiviral activity and pharmacokinetics of GSK2336805 when given as monotherapy and in combination with peginterferon alfa-2a https://t.co/z1rxEymiVf https://t.co/lnQqh2uJ6H

Mar 20, 2024 · 4 shares · 5,238 followers View post →
EurekaMag
@EurekaMag · X

A double-blind, randomized, placebo-controlled study to assess the safety, antiviral activity and pharmacokinetics of GSK2336805 when given as monotherapy and in combination with peginterferon alfa-2a https://t.co/2stAJer4Re https://t.co/FM4IbJeqLT

Mar 20, 2024 · 7 shares · 6,542 followers View post →
Andrew Waye, PhD
@cannabis-scientist.bsky.social · Bluesky

A double-blind, randomized, placebo-controlled study of the safety and effects of CBN with and without CBD on sleep quality pubmed.ncbi.nlm.nih.gov/37796540/

Oct 19, 2023 · 2 likes · 2 shares View post →
Meloar Freilhec
@MeloarFreilhec · X

L'andrographis paniculata semble avoir des propriétés anti-inflammatoires et est efficace contre l'arthrose. Utilisée pendant un essai qui a duré plusieurs mois, sans problèmes graves remontés. (300 à 600 mg de ParActin) https://t.co/vduYhiX9Nr ; https://t.co/3zEyUxbEws

Oct 31, 2021 · 524 followers View post →
abdul ghani qiq
@cintaforex · X

https://t.co/fuiKwPnEO1

Jul 25, 2021 · 75,427 followers View post →
Kabuto
@DrStarWolf · X

@NuclearYoshi @vonbateman Scepticism leads to septic choc :A double blind randomized placebo-controlled study to assess the stupidness of the patients New English journal of Moron

Mar 2, 2021 · 4 likes · 8,255 followers View post →
DLowey
@DLowey1 · X

RT @DrMitchLow: Knee osteoarthritis pain? Try Andrographis paniculata. A new double‐blind, randomised, placebo‐controlled study has assesse…

Apr 18, 2019 · 1 share · 6 followers View post →
Dr Mitchell low
@DrMitchLow · X

Knee osteoarthritis pain? Try Andrographis paniculata. A new double‐blind, randomised, placebo‐controlled study has assessed the efficacy of Andrographis paniculata extract on pain reduction in subjects with #knee #osteoarthritis. # inflammation https://t.co/zL4lOPQyXV

Apr 16, 2019 · 1 like · 1 share · 101 followers View post →