April 2019 PMID 30975196

Safety and efficacy of curcumin versus diclofenac in knee osteoarthritis: a randomized open-label parallel-arm study.

Dhaneshwar Shep, Chitra Khanwelkar, Prakashchandra Gade, Satyanand Karad

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Mentions

92
Peak: 15 in Jun 2019
across 7 sources since Jun 2019

Extended reach

3,599,666
potential audience

Total likes

57,193

Video views

3,171,579

Mentions per month

Jun 2019 – Nov 2025

Where it's discussed

  • X / Twitter54 posts
  • Instagram16 posts
  • Facebook7 posts
  • TikTok6 posts
  • News5 articles
  • YouTube2 videos
  • Reddit2 posts

AI synopsis

What people are saying

The overall tone emphasizes the significance of the study’s results, with many posts praising the comparable efficacy of curcumin to diclofenac and highlighting its fewer adverse effects, such as weight loss and gastrointestinal issues. Words like 'game changer', 'valuable information', and 'help millions' underscore the perceived high impact of these findings on both individual health choices and broader treatment approaches.

AgreementModerate agreement

Most discussions support the study’s conclusion that curcumin is as effective as diclofenac with fewer side effects, indicated by positive terms like 'matches', 'similar', and 'better tolerance'.

InterestHigh interest

Posts demonstrate high interest, with many referencing the health benefits, study details, and implications for arthritis treatment, suggesting active engagement.

EngagementHigh engagement

Numerous comments delve into study specifics, compare options, and reference potential applications, showing deep analysis and interest in the research findings.

ImpactHigh impact

Multiple discussions highlight the potential for curcumin to influence arthritis management practices and even public health messaging, indicating high practical significance.

Abstract in brief

  • This study compared the effects of curcumin and diclofenac in treating knee osteoarthritis and found that both treatments provided similar pain relief and improvement in knee function.
  • Curcumin was associated with fewer side effects, such as less flatulence, weight loss, and stomach ulcers, and fewer adverse events overall.
  • The results suggest that curcumin could be a safer alternative to diclofenac for managing knee osteoarthritis, offering comparable benefits with better tolerance.]

Top posts

Most liked on X and Bluesky
Krzysztof Kukliński, obrońca praw człowieka
@pamiechomeblog · X

#kurkumina tak samo dobra, a bez skutków ubocznych. Dodatkowy efekt uboczny spadek wagi. Bezpieczeństwo i skuteczność kurkuminy w porównaniu z diklofenakiem w chorobie zwyrodnieniowej stawu kolanowego: randomizowane, otw. badanie równoległe z ramieniem https://t.co/x7ctHCmLIB

Sep 27, 2022 · 5 likes · 3 shares · 3,464 followers View post →
TheLiverDoc™
@theliverdr · X

3/ Now this study you shared - Safety and efficacy of curcumin versus diclofenac in knee osteoarthritis: a randomized open-label parallel-arm study Note the study design (C pic) Best evidence for safety and efficacy - randomized double blind controlled trial which this study isnt https://t.co/SHBjlQeRRj

Feb 16, 2021 · 4 likes · 318,982 followers View post →
Dr Pooja Garg
@poojagarg1111 · X

https://t.co/17yuaQT9BO

Feb 29, 2024 · 3 likes · 28,332 followers View post →
Lina
@Linaguasca · X

CÚRCUMA ESTUDI Seguretat i eficàcia de la curcumina versus diclofenac en l'artrosi de genoll https://t.co/IHQQ5oZNUN

Aug 20, 2024 · 3 likes · 1 share · 7,267 followers View post →
Robby Bowers DO, PhD
@TheDrROBO · X

Published earlier this year...shows similar efficacy between curcumin and diclofenac but better tolerance with curcumin in knee OA patients. #knee #osteoarthritis #kneeosteoarthritis #nsaids #orthopedics #kneepain #curcumin https://t.co/VXRRkv2FYG https://t.co/5pmKcWi14g

Aug 23, 2019 · 2 likes · 1 share · 2,524 followers View post →
Suphil Philipose
@Suphee33 · X

This latest research is a solution to help millions suffering silently from arthritis, who are intolerant to the side effects of non-steroidal anti-inflammatory drugs. https://t.co/LQ8lrFu51r @KailashChandOBE @DrAseemMalhotra

Jun 15, 2019 · 2 likes · 458 followers View post →

All mentions

Bart Landuyt
@RealBartLanduyt · X

@vrtnws Ca. 100 jaar geleden sponsorde Rockefeller nieuwe geneeskunde boeken. Daarin werden natuurlijke, goed werkende geneesmiddelen geweerd. Verschillende generaties artsen missen essentiële kennis. Mooi voorbeeld: curcuma is beter dan diclofenac voor reuma. https://t.co/qKQEXtcklB

Nov 2, 2025 · 399 followers View post →
DrCPainMD
@drc_painmd · X

Curcumin (500 mg, 3x/day) matches diclofenac for pain relief in knee osteoarthritis, with fewer side effects! Study: “Safety and efficacy of curcumin versus diclofenac in knee osteoarthritis” (PMID: 30975196). #Curcumin #PainRelief #Osteoarthritis

Jun 12, 2025 · 4 followers View post →
Manu_K_talà ✌️
@Manu_K_tala · X

RT @Linaguasca: CÚRCUMA ESTUDI Seguretat i eficàcia de la curcumina versus diclofenac en l'artrosi de genoll https://t.co/IHQQ5oZNUN

Aug 21, 2024 · 1 share · 5,354 followers View post →
Lina
@Linaguasca · X

CÚRCUMA ESTUDI Seguretat i eficàcia de la curcumina versus diclofenac en l'artrosi de genoll https://t.co/IHQQ5oZNUN

Aug 20, 2024 · 3 likes · 1 share · 7,267 followers View post →
Bart Landuyt
@RealBartLanduyt · X

@HoeyberghsJeff Een mooi voorbeeld is de studie hieronder die diclofenac vergelijkt met curcumine. Het natuurproduct werkt even goed, maar met minder neveneffecten voor de behandeling van osteoarthritis. https://t.co/qKQEXtcklB

Jun 15, 2024 · 1 like · 399 followers View post →
Catrin Williams
@jazzbluecat · X

Looking for recommendations for high quality turmeric supplements following a paper that says this is just as effective as Diclofenac for pain relief https://t.co/X8VUDlKy43

May 14, 2024 · 2 likes · 264 followers View post →
LifetimeHip
@LifetimeHip · X

Knee OA Curcumin (tumeric) vs diclofenac (n=139) 500mg x3/d v 50mg x2/d ⬇ in Pain + KOOS similar at 14d+28d ⬇flatulence (p <0.01) at 7d ⬇weight + ⬇ulcer (p <0.01) at 28d 0 v 19 needed H2 blockers 13% v 38% adverse effects @BioMedCentral via https://t.co/8m1iBGPASU https://t.co/TyEiBLlT0l

May 12, 2024 · 393 followers View post →
Dr Pooja Garg
@poojagarg1111 · X

https://t.co/17yuaQT9BO

Feb 29, 2024 · 3 likes · 28,332 followers View post →
Rheuma Doc
@LastManStand85 · X

The Paper https://t.co/l7XEsIamUV

Feb 2, 2024 · 4,344 followers View post →
Carolina Pharma
@CarolinaPharma · X

Reference: https://t.co/VJObwZI6Nm Unlock the full potential of turmeric! Join us as we delve into the remarkable health benefits of curcumin, turmeric's active ingredient, in managing arthritis pain.

Jul 7, 2023 · 2 followers View post →
Sebastian Castillo
@castillobuiles · X

@JulioBasulto_DN Sin embargo puede ser efectivo antiinflamatorio para pacientes con poca tolerancia al diclofenaco: https://t.co/OhOH3HVH7p

Jun 20, 2023 · 517 followers View post →
Sebastian Castillo
@castillobuiles · X

@ElNutriDice @JulioBasulto_DN Sin embargo si tuvo efecto anti inflamatorio similar al diclofenaco: https://t.co/OhOH3HVH7p

Jun 20, 2023 · 517 followers View post →
protopss
@protopss · X

@drdavidliew @joannamarco @RheumNow RCT #2: "Safety and efficacy of curcumin versus diclofenac in knee osteoarthritis: a randomized open-label parallel-arm study" https://t.co/NXIUYeudLL.

Nov 15, 2022 · 12 followers View post →
protopss
@protopss · X

@MrMuscletov @REV_Insulin_Res @KenDBerryMD What is your take on these RCTs? A: Safety and efficacy of curcumin versus diclofenac in knee osteoarthritis: a randomized open-label parallel-arm study https://t.co/Zfdgutv0sT

Oct 9, 2022 · 12 followers View post →
Izabela Galczak
@Igazalka · X

RT @pamiechomeblog: #kurkumina tak samo dobra, a bez skutków ubocznych. Dodatkowy efekt uboczny spadek wagi. Bezpieczeństwo i skuteczność…

Sep 27, 2022 · 3 shares · 17 followers View post →
Meggy
@Meggy73336095 · X

RT @pamiechomeblog: #kurkumina tak samo dobra, a bez skutków ubocznych. Dodatkowy efekt uboczny spadek wagi. Bezpieczeństwo i skuteczność…

Sep 27, 2022 · 3 shares · 184 followers View post →
Brajan
@Darek41273854 · X

RT @pamiechomeblog: #kurkumina tak samo dobra, a bez skutków ubocznych. Dodatkowy efekt uboczny spadek wagi. Bezpieczeństwo i skuteczność…

Sep 27, 2022 · 3 shares · 299 followers View post →
Krzysztof Kukliński, obrońca praw człowieka
@pamiechomeblog · X

#kurkumina tak samo dobra, a bez skutków ubocznych. Dodatkowy efekt uboczny spadek wagi. Bezpieczeństwo i skuteczność kurkuminy w porównaniu z diklofenakiem w chorobie zwyrodnieniowej stawu kolanowego: randomizowane, otw. badanie równoległe z ramieniem https://t.co/x7ctHCmLIB

Sep 27, 2022 · 5 likes · 3 shares · 3,464 followers View post →
number_309
@number_309 · X

https://t.co/huqKrrjpnJ

Sep 13, 2022 · 56 followers View post →
Recovering Vegan
@VeganRecovering · X

@SteakAndIron @SuperNutrition_ @Onnit @CuraminNZ What's interesting is that in trials with curcumin vs NSAIDS, the people who took the curcumin also lost weight! https://t.co/p4h8Mi2KfE

Jun 30, 2022 · 1 like · 22,182 followers View post →
protopss
@protopss · X

@MunchPhd Another RCT: "...139 patients with knee OA were randomly assigned to receive either a curcumin 500-mg (BCM-95®) capsule three times daily or a diclofenac 50-mg tablet two times daily for 28 days." https://t.co/ZfdgutM3uT

Jun 19, 2022 · 12 followers View post →
Cardiotabs
@Cardiotabs · X

Did you know? Curcumin can help with knee pain and joint mobility. A recent study compared curcumin to an NSAID like Advil to see which would help more with knee pain relief. https://t.co/JfBZrpNJsk https://t.co/HCjJ4ZtArx

Mar 15, 2022 · 2,169 followers View post →
protopss
@protopss · X

@jmicrobe9 @Astraea_Muse @DragonNexus @BadMedicalTakes Another RCt on Curcumin: Safety and efficacy of curcumin versus diclofenac in knee osteoarthritis: a randomized open-label parallel-arm study https://t.co/X0mp6thv6V

Aug 15, 2021 · 12 followers View post →
protopss
@protopss · X

@CakeNutrition This study might interest you: "Safety and efficacy of curcumin versus diclofenac in knee osteoarthritis: a randomized open-label parallel-arm study" https://t.co/X0mp6thv6V

Aug 15, 2021 · 2 likes · 12 followers View post →
Active Atoms
@ActiveAtoms · X

@NightVoyagers It's definitely not for everyone. But one study found that people who took turmeric extract instead of a prescription anti-inflammatory had the similar levels of relief from osteoarthritis and less negative side effects. You can check out the article here https://t.co/B5AqmzmNQe

Apr 29, 2021 · 12 followers View post →
TheLiverDoc™
@theliverdr · X

3/ Now this study you shared - Safety and efficacy of curcumin versus diclofenac in knee osteoarthritis: a randomized open-label parallel-arm study Note the study design (C pic) Best evidence for safety and efficacy - randomized double blind controlled trial which this study isnt https://t.co/SHBjlQeRRj

Feb 16, 2021 · 4 likes · 318,982 followers View post →
Ghofran Sulaimani
@G_Sulaimani · X

RT @SBPM_Riyadh: Activity day topics : "Premarital Screening" By: Dr Gufran Sulaimani R2 @G_Sulaimani " Safety and efficacy of Curcumin…

Jan 21, 2021 · 2 shares · 432 followers View post →
برنامج الوبائيات الحقلي
@Saudi_FETP · X

RT @SBPM_Riyadh: Activity day topics : "Premarital Screening" By: Dr Gufran Sulaimani R2 @G_Sulaimani " Safety and efficacy of Curcumin…

Jan 21, 2021 · 2 shares · 4,505 followers View post →
Saudi Board of Preventive Medicine , Riyadh
@SBPM_Riyadh · X

Activity day topics : "Premarital Screening" By: Dr Gufran Sulaimani R2 @G_Sulaimani " Safety and efficacy of Curcumin versus Diclofenac in Knee Osteoarthritis" By: Dr Mishari Alrashidi R2 https://t.co/W9S2ZMfnsq

Jan 21, 2021 · 2 shares · 1,290 followers View post →
PedsAnesthesia.Net
@PedsAnesNet · X

@garyschwartzmd @ShaliniShahMD @dr_rajgupta @jeffgadsden @NarouzeMD @ASRA_Society @EMARIANOMD @KohanLynn @AmyPearsonMD @andreanicolmd @Ropivacaine @ESchwenkMD Easier with the link... https://t.co/EIfM4bhf6U

Nov 22, 2020 · 5,164 followers View post →
Alzheimer's Prevention
@AlzheimersPrev2 · X

@Suphee33 @AyoksAJ @NICEComms @MHRAgovuk @Arthritis_ACTN If you can treat Arthritis with Curcumin, it doesn't take a genius to realize that it can also prevent Arthritis. These folks are on the payroll of the industry and as everyone knows, big pharma is spends more money in lobbying than the oil industry. https://t.co/zoIJebLsVU

May 17, 2020 · 407 followers View post →
OrthoTweets
@TweetsOrtho · X

RT @TheDrROBO: Published earlier this year...shows similar efficacy between curcumin and diclofenac but better tolerance with curcumin in k…

Aug 24, 2019 · 1 share · 6,438 followers View post →
Robby Bowers DO, PhD
@TheDrROBO · X

Published earlier this year...shows similar efficacy between curcumin and diclofenac but better tolerance with curcumin in knee OA patients. #knee #osteoarthritis #kneeosteoarthritis #nsaids #orthopedics #kneepain #curcumin https://t.co/VXRRkv2FYG https://t.co/5pmKcWi14g

Aug 23, 2019 · 2 likes · 1 share · 2,524 followers View post →
Columbia Pain
@ColumbiaPain · X

https://t.co/Ry37QUiasN

Aug 23, 2019 · 404 followers View post →
‏Amer Alreshidi
@pharmacist_ksa · X

Curcumin for osteoporosis https://t.co/6AucUOUFCL

Aug 22, 2019 · 392 followers View post →
Suphil Philipose
@Suphee33 · X

@ArthritisDigest Safety and efficacy of curcumin versus diclofenac in knee osteoarthritis: https://t.co/LQ8lrFctCR

Jul 23, 2019 · 458 followers View post →
Alzheimer's Prevention
@AlzheimersPrev2 · X

In this randomized, open-label, parallel, active controlled clinical study, 139 patients with knee OA were randomly assigned to receive either a curcumin 500-mg (BCM-95®) capsule three times daily or a diclofenac 50-mg tablet two times daily for 28 days.  https://t.co/zoIJebLsVU

Jul 19, 2019 · 407 followers View post →
Suphil Philipose
@Suphee33 · X

@DelthiaRicks @docmmiller What if we a have natural painkiller with side benefits instead of the nasty side effects associated with pharmaceutical drugs. https://t.co/LQ8lrFu51r

Jul 10, 2019 · 458 followers View post →
Nuala Woulfe
@Nuala_Woulfe · X

Safety and efficacy of curcumin versus diclofenac in knee osteoarthritis: a randomised open-label parallel-arm study | Trials | Full Text #tumeric #osteoarthritis #health #study #glasthule https://t.co/h6ai6Raa8U

Jul 8, 2019 · 1,792 followers View post →
Suphil Philipose
@Suphee33 · X

@GoogleAds @GoodTimePrint Hi Google, we have a published research on our product that has evidenced to help more than 10 million people in the UK who suffer from Arthritis. We are looking to roll out a campaign that will help the messaging. How can google help.? https://t.co/LQ8lrFu51r

Jun 18, 2019 · 458 followers View post →
Alzheimer's Prevention
@AlzheimersPrev2 · X

@usainbolt 10 Million people in the UK suffer from Arthritis. This is a game changer.. https://t.co/zoIJebLsVU

Jun 16, 2019 · 407 followers View post →
Suphil Philipose
@Suphee33 · X

@natifernandezb @Rheum_Matters @astridpaats Game changer.. https://t.co/LQ8lrFu51r

Jun 16, 2019 · 458 followers View post →
Rua Wetters
@Rua_2 · X

Curcumin Tumeric https://t.co/kChJ4Pxwuc

Jun 15, 2019 · 73 followers View post →
Suphil Philipose
@Suphee33 · X

This latest research is a solution to help millions suffering silently from arthritis, who are intolerant to the side effects of non-steroidal anti-inflammatory drugs. https://t.co/LQ8lrFu51r @KailashChandOBE @DrAseemMalhotra

Jun 15, 2019 · 2 likes · 458 followers View post →
Alzheimer's Prevention
@AlzheimersPrev2 · X

@Arthritisie Keep up with the fantastic work. I hope this latest research will be beneficial Millions of people suffering from Arthritis .. https://t.co/zoIJebLsVU

Jun 13, 2019 · 407 followers View post →
Alzheimer's Prevention
@AlzheimersPrev2 · X

@LillyRheumEU Keep up with the fantastic work. I hope this latest research helps Millions of people suffering from Arthritis .. https://t.co/zoIJebLsVU

Jun 13, 2019 · 407 followers View post →
Alzheimer's Prevention
@AlzheimersPrev2 · X

You could help Millions of people get some relief just by publishing this latest research.. https://t.co/zoIJebLsVU @karinab

Jun 13, 2019 · 407 followers View post →
Peter Dingle (PhD)
@drdingle · X

curcumin supplement is as good the drug diclofenac in knee osteoarthritis: a randomized open-label parallel-arm study https://t.co/2cXRbiGv52 #trialsjournal

Jun 12, 2019 · 2,281 followers View post →
Alzheimer's Prevention
@AlzheimersPrev2 · X

@on_found @MEFISTO_H2020 Free valuable information.. https://t.co/zoIJebLsVU

Jun 12, 2019 · 407 followers View post →
Alzheimer's Prevention
@AlzheimersPrev2 · X

@ottobockuk Valuable free information.. https://t.co/zoIJebLsVU

Jun 12, 2019 · 407 followers View post →
Alzheimer's Prevention
@AlzheimersPrev2 · X

@UoAEpi @DanielWhibley @umichmedicine Valuable information.. https://t.co/zoIJebLsVU

Jun 12, 2019 · 407 followers View post →
Alzheimer's Prevention
@AlzheimersPrev2 · X

@DrAmirKhanGP I hope you find this information valuable. https://t.co/zoIJebLsVU

Jun 12, 2019 · 407 followers View post →
Alzheimer's Prevention
@AlzheimersPrev2 · X

@ndosie Information is valuable. https://t.co/zoIJebLsVU

Jun 12, 2019 · 407 followers View post →
Alzheimer's Prevention
@AlzheimersPrev2 · X

@DrJamesPrior @PCSciences @VersusArthritis @NIHRSPCR @KeeleUniversity Free information.. https://t.co/zoIJebLsVU

Jun 12, 2019 · 407 followers View post →
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2019 Apr 11;20(1):214. doi: 10.1186/s13063-019-3327-2. PMID: 30975196; PMCID: PMC6460672. - Haroyan A, Mukuchyan V, Mkrtchyan N, Minasyan N ...

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өвдөгний үенд PRP эмчилгээ хэр үр дүнтэй юм бол оо
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com/articles/10.1186/s13063-019-3327-2 https://www.health.harvard. edu/blog/curcumin-for-arthritis-does-it- really-work-2019111218290 · No ...

Feb 12, 2024 View →
Beneficios del Ayuno Intermitente en Enfermedades Autoinmunes ...
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doi: 10.1186/s13063-019-3327-2. PMID: 30975196; PMCID: PMC6460672. - Haroyan A, Mukuchyan V, Mkrtchyan N, Minasyan N, Gasparyan S, Sargsyan ...

Feb 1, 2024 View →
En nuestro último video, "Café: ¿Amigo o Enemigo de Tu Artritis ...
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doi: 10.1186/s13063-019-3327-2. PMID: 30975196; PMCID: PMC6460672. - Haroyan A, Mukuchyan V, Mkrtchyan N, Minasyan N, Gasparyan S, Sargsyan ...

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com/articles/10.1186/s13063-019-3327-2 https://www.health.harvard.edu/blog/curcumin- for-arthritis-does-it-really-work-2019111218290.

Dec 9, 2023 View →
What Are Dietary Supplements?
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https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-019-3327-2; Vitamin D. (2024). https://www.cdc.gov/infant-toddler-nutrition ...

Nov 13, 2023 View →
5 Benefits of Turmeric That Are Backed by Science
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... 10.1186/s13063-019-3327-2; Source: https://pubmed.ncbi.nlm.nih.gov/26592847/; Source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476912/#B3 ...

Mar 28, 2023 View →
Cúrcuma e ibuprofeno : r/Supplements
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... 10.1186/s13063-019-3327-2. Un estudio ha demostrado que la** curcumina actúa como un potente compuesto antiúlcera para proteger contra la ...

Dec 21, 2022 View →
Turmeric and ibuprofen : r/Supplements
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... 10.1186/s13063-019-3327-2. A study has shown that curcumin acts as a potent anti-ulcer compound to protect indomethacin (NSAID)-induced ...

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GURKEMEJE ELLER GIGTMEDICIN? Har du ledsmerter, slidgigt ...
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GURKEMEJE ELLER GIGTMEDICIN? Har du ledsmerter, slidgigt eller leddegigt? Hvis ja, bør du spise gurkemeje med sort peber hver dag.

Jun 18, 2022 View →
O Grassfed da Pura Vida, é um Whey Protein concentrado e integral ...
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Referência: DOI: 10.1186/s13063-019-3327-2. more. View all 23 comments. November 6 · bioexatasuplementos's profile picture. bioexatasuplementos.

Apr 26, 2022 View →
Love Ya Guts - Bentonite clay Mask recipe ...
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jep.2004.11.004 Curcumin: DOI: 10.1186/s13063-019-3327-2 Garlic: DOI: 10.1515/hmbci-2024-0019 Green tea: ...

Nov 8, 2020 View →