The social discussions reflect a strong interest and concern about the variability in MDMA content and dissolution rates, with phrases like 'worrying MDMA facts' and mentions of the unpredictability of effects, which underscores the potential health risks and need for regulation. The tone and choice of words convey a sense of urgency and importance, aligning with the higher scores in interest and impact.
AgreementModerate agreement
Most discussions acknowledge the study’s findings about MDMA variability and agree on the potential health risks posed to users, indicated by phrases like 'worrying MDMA facts' and discussions of public health concerns.
InterestHigh interest
The social discussions demonstrate high interest, with reactions highlighting the significance of the findings and raising questions about regulation and safety, reflecting curiosity and concern.
EngagementHigh engagement
Multiple posts delve into details such as variability within batches, effects on users, and implications for regulation, showing deep engagement with the research and its implications.
ImpactHigh impact
The discussions emphasize the practical health and safety impacts, suggesting that the findings could influence drug regulation policies and harm reduction strategies, indicating high perceived impact.
Abstract in brief
The study analyzed MDMA tablets collected in the UK between 2001 and 2018 and found that recent samples, especially from 2016-2018, tend to have higher MDMA content, with some exceeding 100mg per tablet, and showed significant variability both between and within batches.
Dissolution tests revealed no clear link between tablet characteristics and how quickly the drug is released, meaning users cannot predict if a tablet will be fast or slow-releasing based on appearance or other factors.
The variability in both MDMA content and dissolution rates poses health risks, as high or delayed release tablets can lead to toxic effects or prolonged intoxication, increasing the danger of redosing and negative health consequences.]
The high demand for ecstasy tablets, professional drug checking services, & other quality control measures have resulted in high-content tablets produced/sold in EU countries. Varying content & dissolution profiles put PWUD at risk, regulation could help! https://t.co/NBGyfTGuOC
May 2, 2019 · 10 likes · 5 shares · 2,755 followersView post →
CV
Claudio Vidal
@claudiovidalg · X
This study addresses an important question I have thinking of a lot. Ecstasy tablets from a same batch could not contain the same amount of MDMA because the illicit nature of their production (lack of quality control). https://t.co/LoNp55mMGv https://t.co/1oBTnPWigQ
New drug-testing paper: a lot of variability in dosage and release time within single batches of MDMA/ecstasy. Therefore, doses from the same batch may have different effects
https://t.co/rzPvu0Ba9I https://t.co/ktZ3og2HgV
May 3, 2019 · 5 likes · 1,260 followersView post →
PH
Prison_Health
@Prison_Health · X
Variability in content and dissolution profiles of #MDMA tablets collected in the UK between 2001 and 2018 - A potential risk to users? [a] https://t.co/3NfxI9DFJa HT Pharmaceutical Sciences Clinical Academic Group @kingscollegelon #SUD #PWUD #Ecstasy https://t.co/Un6Hesi4np
Variability in content and dissolution profiles of #MDMA tablets collected in the UK between 2001 and 2018 - A potential risk to users? [a] https://t.co/3NfxI9DFJa HT Pharmaceutical Sciences Clinical Academic Group @kingscollegelon #SUD #PWUD #Ecstasy https://t.co/P82KpvIrtQ
Ecstasy is known as a recreational drug that can cause feelings of happiness and love. However, in some cases, overdose from MDMA can lead to life-threatening conditions, especially due to high doses or contaminated…
Ecstasy is often seen as a feel-good drug, but overdose can cause severe, life-threatening conditions. Analyses show many pills contain high and variable doses of active substances, increasing overdose risk and…
This study compares UK data with other countries to address public health authorities' concerns over the prevalence of 3,4-Methylenedioxymethamphetamine (MDMA, Ecstasy) tablets.
Variability in content and dissolution profiles of #MDMA tablets collected in the UK between 2001 and 2018 - A potential risk to users? [a] https://t.co/3NfxI9DFJa HT Pharmaceutical Sciences Clinical Academic Group @kingscollegelon #SUD #PWUD #Ecstasy https://t.co/Un6Hesi4np
Variability in content and dissolution profiles of #MDMA tablets collected in the UK between 2001 and 2018 - A potential risk to users? [a] https://t.co/3NfxI9DFJa HT Pharmaceutical Sciences Clinical Academic Group @kingscollegelon #SUD #PWUD #Ecstasy https://t.co/P82KpvIrtQ
ASI's pioneering research flags worrying MDMA facts:-
1 Concentration of MDMA in tablets is going up.
2 Tablets from the same batch can vary in MDMA content by up to 250%.
3 Tablets from the same batch can release MDMA at significantly varying rates.
See https://t.co/xGyGlLD30i
RT @maier_larissa: The high demand for ecstasy tablets, professional drug checking services, & other quality control measures have resulted…
May 3, 2019 · 5 shares · 13,486 followersView post →
JP
Joseph Palamar
@JosephPalamar · X
New drug-testing paper: a lot of variability in dosage and release time within single batches of MDMA/ecstasy. Therefore, doses from the same batch may have different effects
https://t.co/rzPvu0Ba9I https://t.co/ktZ3og2HgV
May 3, 2019 · 5 likes · 1,260 followersView post →
LB
Leo Beletsky
@LeoBeletsky · X
RT @maier_larissa: The high demand for ecstasy tablets, professional drug checking services, & other quality control measures have resulted…
May 3, 2019 · 5 shares · 17,385 followersView post →
S
Spellyr
@Sp3llyr · X
RT @maier_larissa: The high demand for ecstasy tablets, professional drug checking services, & other quality control measures have resulted…
Variability in content and dissolution profiles of MDMA tablets collected in the UK between 2001 and 2018 – a potential risk to users? - Couchman - - Drug Testing and Analysis - Wiley Online Library https://t.co/qWXlHhyaNo
RT @maier_larissa: The high demand for ecstasy tablets, professional drug checking services, & other quality control measures have resulted…
May 2, 2019 · 5 shares · 2,717 followersView post →
LP
Larissa J. Maier, PhD
@LarissaJMaier · X
The high demand for ecstasy tablets, professional drug checking services, & other quality control measures have resulted in high-content tablets produced/sold in EU countries. Varying content & dissolution profiles put PWUD at risk, regulation could help! https://t.co/NBGyfTGuOC
May 2, 2019 · 10 likes · 5 shares · 2,755 followersView post →
JH
Jeff Hackett
@Jeff04091958 · X
New MDMA paper from LTG members: https://t.co/KGA21pD3Rd
This study addresses an important question I have thinking of a lot. Ecstasy tablets from a same batch could not contain the same amount of MDMA because the illicit nature of their production (lack of quality control). https://t.co/LoNp55mMGv https://t.co/1oBTnPWigQ
From the paper: "For MDMA users, our data suggest that analysis of a single tablet from a batch cannot guarantee that all others in the same batch are of the same content." https://t.co/htFvGr7vVt
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