MDMA-assisted psychotherapy for treatment of PTSD: study design and rationale for phase 3 trials based on pooled analysis of six phase 2 randomized controlled trials.
Participants broadly agree that the article presents promising evidence supporting MDMA-assisted psychotherapy as an effective treatment for PTSD, with phrases like 'groundbreaking' and 'hope for the future' indicating strong positive sentiment. The tone is optimistic and analytical, often referencing FDA approval and large-scale trial results, which demonstrate a high degree of interest and engagement.
AgreementModerate agreement
Most discussions support the positive findings and potential of MDMA-assisted psychotherapy, emphasizing its efficacy and progress toward phase 3 trials.
InterestHigh interest
Participants display high curiosity and enthusiasm, often highlighting the breakthrough nature and clinical significance of the research.
EngagementHigh engagement
Several discussions reference the methodology, regulatory progress, and potential implications, showing deep involvement in understanding the study’s impact.
ImpactHigh impact
The conversations recognize the research’s high potential to transform PTSD treatment, with mentions of FDA approvals and promising results.
Abstract in brief
The pooled analysis of six phase 2 trials shows that MDMA-assisted psychotherapy significantly reduces PTSD symptoms, with the active group experiencing greater improvements than the placebo group.
The studies involved administering MDMA (75-125 mg) during therapy sessions spaced out a month apart, with additional preparatory and follow-up sessions, and found MDMA to be well tolerated.
These findings support designing phase 3 trials to further evaluate MDMA-assisted psychotherapy as an effective treatment for PTSD, given its large effect size and safety profile.]
17)באזור 2007-8 התחיל המחקר הקליני בטיפול משולב MDMA, ולפני ארבע שנים, כשהסתיים שלב 2 אחרון (בוצעו 6 ניסויים של שלב 2 בטיפול), הוא עלה לתודעה הציבורית, כי התוצאות הסטטיסטיות היו די חזקות ליעילות של הטיפול.
https://t.co/QXypx5ry3p
May 20, 2021 · 40 likes · 1,766 followersView post →
BD
Brian D. Earp, Ph.D.
@briandavidearp · X
MDMA-assisted psychotherapy for treatment of PTSD: study design and rationale for phase 3 trials based on pooled analysis of six phase 2 randomized controlled trials | SpringerLink https://t.co/PFQMN7aZuj
Jun 1, 2019 · 16 likes · 4 shares · 26,108 followersView post →
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Todd Harrison
@todd_harrison · X
A study found that "MDMA-assisted psychotherapy was efficacious and well tolerated in a large sample of adults with PTSD." h/t @tomangell
https://t.co/aIoJBt3nIG
May 8, 2019 · 13 likes · 2 shares · 69,417 followersView post →
SC
scott cunningham
@causalinf · X
MDMA + psychotherapy assisted treatment for PTSD RCTs just out. Large reductions in PTSD symptoms in treatment group. https://t.co/vY7ZZMCuBN https://t.co/LZOCSONmV4
May 7, 2019 · 10 likes · 1 share · 52,395 followersView post →
PT
Psychedelics Today
@PsydelicsToday · X
MDMA-assisted psychotherapy for treatment of PTSD : study design and rationale for phase 3 trials based on pooled analysis of six phase 2 randomized controlled trials https://t.co/uFcn4jPLWi
May 8, 2019 · 9 likes · 3 shares · 41,622 followersView post →
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BryanRoth
@zenbrainest · X
MDMA treats PTSD
https://t.co/jtzUy9lnLF
May 30, 2019 · 9 likes · 2 shares · 17,146 followersView post →
Research indicates MDMA-assisted psychotherapy significantly reduces PTSD symptoms, showing safety and effectiveness in phase 2 trials, supporting further study in phase 3 trials for this innovative treatment approach.
This video explains how MDMA interacts with brain serotonin transporters, leading to increased monoamine release. It covers molecular interactions, TAAR1 signaling, and the role of MDMA in PTSD treatment through…
@D__Nickles @RickDoblin I understand your criticisms, but apparently the FDA thought this pooled analysis was sufficient to move to phase 3? https://t.co/l3xpX2vaQV
#MDMA assisted psychotherapy for treating #PTSD has begun FDA-approved phase 3 trials. Check out the full article discussing the six phase 2 randomized controlled trials which showed how effective this #psychedelictherapy can be:
https://t.co/QRzbJ9DIxB
17)באזור 2007-8 התחיל המחקר הקליני בטיפול משולב MDMA, ולפני ארבע שנים, כשהסתיים שלב 2 אחרון (בוצעו 6 ניסויים של שלב 2 בטיפול), הוא עלה לתודעה הציבורית, כי התוצאות הסטטיסטיות היו די חזקות ליעילות של הטיפול.
https://t.co/QXypx5ry3p
May 20, 2021 · 40 likes · 1,766 followersView post →
KD
Kristleifur Daðason
@kristleifur · X
@sveinbjornp Þetta mun vera ritrýnda fræðigreinin sem tekur saman Phase 2 rannsóknirnar.
Þær eru mjög svipaðar og Phase 3. 3. stig er betur fjármagnað. Hægt að fylgja þáttakendum betur eftir og herða upp í rannsóknaraðferðum sem gerir niðurstöður enn skýrari.
https://t.co/fQAkHmGgwN
@Gorman_JG @RichardJGrant They’re already doing this work
MDMA-assisted psychotherapy for PTSD: https://t.co/4H5eJDxOaz
Ketamine for depression: https://t.co/mg7G3Mm5aa
Psilocybin for depression and anxiety: https://t.co/biiPy4Ajr0
Etc
Johns Hopkins leads a lot of this kind of work
Read about the FIRST GROUNDBREAKING TREATMENT for PTSD in 17 YEARS!
NAI Member Institute Medical University of South Carolina and its partners published the results of a study with a CURE RATE of 68%!
https://t.co/iGvKhkBjXo
#ptsd #ScientistsHealingTheWorld
MDMA-assisted psychotherapy for treatment of PTSD: study design and rationale for phase 3 trials based on pooled analysis of six phase 2 randomized controlled trials | SpringerLink
https://t.co/Sg81KpmTyT
Posttraumatic stress disorder is a prevalent mental health condition with substantial impact on daily functioning that lacks sufficient treatment options.
https://t.co/eiUwnC7aoq
MDMA + psychotherapy found to be effective and well-received as a treatment for adults suffering from PTSD. Recent paper evaluates multiple phase 2 clinical trials https://t.co/EL8RtetvK4
Jun 28, 2019 · 3 likes · 4,798 followersView post →
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Sean Wilkes, M.D.
@DrSeanWilkes · X
“#MDMA-assisted #psychotherapy was efficacious and well tolerated in a large sample of adults with #PTSD. These studies supported expansion into phase 3 trials and led to #FDA granting Breakthrough Therapy designation for this promising treatment.” https://t.co/QZmfnxu7nC
RT briandavidearp: RT briandavidearp: MDMA-assisted psychotherapy for treatment of PTSD: study design and rationale for phase 3 trials based on pooled analysis of six phase 2 randomized controlled trials | SpringerLink https://t.co/KcjQKIQsrg
RT @briandavidearp: MDMA-assisted psychotherapy for treatment of PTSD: study design and rationale for phase 3 trials based on pooled analys…
Jun 1, 2019 · 4 shares · 6,353 followersView post →
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Sebastian Hendricks (he/him)
@Hearing4Kids · X
RT briandavidearp: MDMA-assisted psychotherapy for treatment of PTSD: study design and rationale for phase 3 trials based on pooled analysis of six phase 2 randomized controlled trials | SpringerLink https://t.co/KcjQKIQsrg
MDMA-assisted psychotherapy for treatment of PTSD: study design and rationale for phase 3 trials based on pooled analysis of six phase 2 randomized controlled trials | SpringerLink https://t.co/PFQMN7aZuj
Jun 1, 2019 · 16 likes · 4 shares · 26,108 followersView post →
May 30, 2019 · 2 shares · 173 followersView post →
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BryanRoth
@zenbrainest · X
MDMA treats PTSD
https://t.co/jtzUy9lnLF
May 30, 2019 · 9 likes · 2 shares · 17,146 followersView post →
SC
scott cunningham
@causalinf · X
As I wait for IPUMS to put my data together, I thought I'd post a new publication in PSYCHOPHARMACOLOGY. It's a study pooling six RCTs evaluating the causal effect of MDMA on PTSD symptoms. At the moment, you can download it freely. https://t.co/vY7ZZMCuBN
May 21, 2019 · 1 like · 52,395 followersView post →
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Mark Fallu
@brisvegas1 · X
If you are feeling like I am this morning - MDMA shows promise in treatment of PTSD... just saying https://t.co/JrJSoOWDUg
May 18, 2019 · 2 likes · 1,149 followersView post →
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Roni
@RainerFake · X
Video // Hashem Al-Ghaili: Ecstasy shows promising results in treating PTSD https://t.co/aWlXxxWmk2
MDMA-assisted psychotherapy for treatment of PTSD: study design and rationale for phase 3 trials based on pooled analysis of six phase 2 randomized controlled trials https://t.co/c1jqP20Zub
MDMA-assisted psychotherapy for treatment of PTSD: study design and rationale for phase 3 trials based on pooled analysis of six phase 2 randomized controlled trials
https://t.co/wkvcmfGcHg https://t.co/3iOqEiNclD
RT briandavidearp: RT briandavidearp: MDMA-assisted psychotherapy for treatment of PTSD: study design and rationale for phase 3 trials based on pooled analysis of six phase 2 randomized controlled trials | SpringerLink https://t.co/KcjQKIQsrg
MDMA-assisted psychotherapy for treatment of PTSD : study design and rationale for phase 3 trials based on pooled analysis of six phase 2 randomized controlled trials https://t.co/uFcn4jPLWi
May 8, 2019 · 9 likes · 3 shares · 41,622 followersView post →
DH
Dr Seb Henagulph
@drhenagulph · X
Promising results for MDMA in PTSD treatment. If Phase 3 goes as well @MAPS expects FDA approval by 2021...watch this space.
https://t.co/Xb6CMFh3UQ
A study found that "MDMA-assisted psychotherapy was efficacious and well tolerated in a large sample of adults with PTSD." h/t @tomangell
https://t.co/aIoJBt3nIG
May 8, 2019 · 13 likes · 2 shares · 69,417 followersView post →
ML
Matina Liosi
@MatinaLiosi · X
RT @briandavidearp: MDMA-assisted psychotherapy for treatment of PTSD: study design and rationale for phase 3 trials based on pooled analys…
May 8, 2019 · 4 shares · 1,123 followersView post →
TU
The Exponential Growth Understander
@intensivemargin · X
RT @causalinf: MDMA + psychotherapy assisted treatment for PTSD RCTs just out. Large reductions in PTSD symptoms in treatment group. https:…
RT briandavidearp: MDMA-assisted psychotherapy for treatment of PTSD: study design and rationale for phase 3 trials based on pooled analysis of six phase 2 randomized controlled trials | SpringerLink https://t.co/KcjQKIQsrg
MDMA-assisted psychotherapy for treatment of PTSD: study design and rationale for phase 3 trials based on pooled analysis of six phase 2 randomized controlled trials | SpringerLink https://t.co/PFQMN7aZuj
May 7, 2019 · 7 likes · 4 shares · 26,108 followersView post →
A
Arnþór
@arnthorjon · X
#MDMA-assisted #psychotherapy for treatment of #PTSD: study design and rationale for phase 3 trials based on pooled analysis of six phase 2 randomized controlled trials
https://t.co/JCCquKI2Ti
May 7, 2019 · 4 likes · 1,396 followersView post →
SC
scott cunningham
@causalinf · X
MDMA + psychotherapy assisted treatment for PTSD RCTs just out. Large reductions in PTSD symptoms in treatment group. https://t.co/vY7ZZMCuBN https://t.co/LZOCSONmV4
May 7, 2019 · 10 likes · 1 share · 52,395 followersView post →
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