#VisualAbstract: In this trial involving women with vaginal bleeding in early pregnancy, treatment with progesterone during the first trimester did not result in a significantly higher incidence of live births than placebo. Full abstract: https://t.co/MbFFfuC809
A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy.
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May 2019 – Jul 2025Where it's discussed
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X / Twitter114 posts
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News20 articles
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Facebook18 posts
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Blogs5 articles
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YouTube2 videos
AI synopsis
What people are saying
The discussions reflect a blend of skepticism and interest, with some users highlighting that 'progesterone is placebo' and recognizing the study as 'well-designed' but failing to show a significant benefit in live births. Phrases like 'not a proven treatment' and 'these studies should not change everything you do' suggest a cautious approach among healthcare professionals, underscoring a collective realization of the complexity of treating early pregnancy complications.
Several posts express skepticism about the efficacy of progesterone, indicating disagreement with the findings on its benefits.
Many users showed high interest, discussing the implications of the trial and its methodology.
The discussions include references to various studies and individual experiences, suggesting moderate engagement.
Overall, users perceive the study's results as having limited impact on clinical practice, despite some expressing a need for change.
Abstract in brief
- The study investigates the effects of progesterone on pregnancy outcomes in women with vaginal bleeding during early pregnancy, aiming to determine if it improves the likelihood of live births after 34 weeks of gestation.
- A total of 4153 women participated, with 2079 receiving progesterone and 2074 receiving a placebo; results indicated no significant difference in live birth rates between the two groups (75% for progesterone vs. 72% for placebo).
- The findings suggest that progesterone therapy, when given in the first trimester, does not significantly enhance pregnancy outcomes for women experiencing early pregnancy bleeding.
Top posts
Most liked on X and BlueskyMiscarriage affects 1 in 5 pregnancies. Miscarriage can cause excessive bleeding, infection, and complications associated with surgical treatment, as well as substantial psychological harm, including anxiety, depression, and PTSD. Learn more: https://t.co/MbFFfuTIRH
Progesterone given for bleeding in early pregnancy does not increase chance of live birth The New England Journal of Medicine https://t.co/0SwHTwlKZC
Original Article: A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy https://t.co/MbFFfuC809 Editorial: Progesterone for Threatened Abortion https://t.co/5JqXxAh2ST https://t.co/EssFdD65GZ
A Randomized Trial of Progesterone in Women with Bleeding in Early Pregn... https://t.co/yMwrgLzim3 via @YouTube
https://t.co/HYaJ0LYn7Y
All mentions
Impact of Progesterone on Miscarriage Prevention: Insights from PRISM Trial
The PRISM trial is the largest randomised trial in miscarriage prevention, involving over 4000 women. The study evaluated progesterone's effects on early pregnancy bleeding, showing a significant increase in live birth…
Examining Abortion Reversal: Risks and Realities
The video uncovers the controversy surrounding the clandestine handover of a dangerous medication to a supposed pregnant woman. We clarify the facts about abortion reversal and explore its implications based on recent…
@secularprolife Supplemental Pr doesn't improve overall outcomes re miscarriage, only for certain patients https://t.co/p5cqbulRw3 https://t.co/coPfWTtbzD And hypothetical mechanism (competition) is different for APR vs miscarriage... APR is unproven. What should we call that?
@AndreSenteDores @the_mindstone_ @7_kingdoms @titiasuspensa @shanegraybr Sinto mto acabar com sua ilusão. Progesterona é placebo. https://t.co/KT6x15DbDv
No, supplemental progesterone is not a proven treatment for preventing miscarriage in most cases. Available evidence shows a benefit in those with ≥3 miscarriages. https://t.co/p5cqbuljGv There are also some potential risks https://t.co/19PuQSILyb
Dr Chu also looked at the subject of progesterone. There is a signal that low progesterone levels might have a role. But the PRISM study suggested progesterone may help those who have experienced miscarriage already. #PETmiscarriage https://t.co/qqdaw0nAoS
A Randomized Trial of Progesterone in Women with Bleeding in Early Pregn... https://t.co/yMwrgLzim3 via @YouTube
【妊娠初期の出血に対するプロゲステロン投与 】 3%でも変わるなら、プロゲステロン剤投与して欲しいですが
Topic A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy https://t.co/i6z9fQnjfp
A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy https://t.co/FcW6ColsE1 https://t.co/C3GceFbVUY
RT @arricoomarasamy: 1/ PRISM Trial out in the NEJM! 54 extra babies with progesterone, 3% difference in live birth, borderline statistical…
RT @arricoomarasamy: 1/ PRISM Trial out in the NEJM! 54 extra babies with progesterone, 3% difference in live birth, borderline statistical…
Current Issue: Progesterone for Threatened Abortion (a Commentary on a Randomized Trial of Progesterone in Women With Bleeding in Early Pregnancy https://t.co/B2bUb4L7d4
Current Issue: A Randomized Trial of Progesterone in Women With Bleeding in Early Pregnancy https://t.co/TnEUpzaeTq
https://t.co/HYaJ0LYn7Y
RT @arricoomarasamy: 1/ PRISM Trial out in the NEJM! 54 extra babies with progesterone, 3% difference in live birth, borderline statistical…
Current Issue: A Randomized Trial of Progesterone in Women With Bleeding in Early Pregnancy https://t.co/brezX0eor5
RT @arricoomarasamy: 1/ PRISM Trial out in the NEJM! 54 extra babies with progesterone, 3% difference in live birth, borderline statistical…
RT @arricoomarasamy: 1/ PRISM Trial out in the NEJM! 54 extra babies with progesterone, 3% difference in live birth, borderline statistical…
RT @draredondoania: https://t.co/lHoNIbxbDv
RT @NEJM: #VisualAbstract: Progesterone in Women with Bleeding in Early Pregnancy https://t.co/MbFFfuC809 #OBGYN https://t.co/s07odqq5Wt
RT @arricoomarasamy: 1/ PRISM Trial out in the NEJM! 54 extra babies with progesterone, 3% difference in live birth, borderline statistical…
@jd_wilko I downloaded it from NEJM website? chrome-extension://oemmndcbldboiebfnladdacbdfmadadm/https://t.co/KwjTpq2yvf
@mikejohansenmd @raj_mehta @Info_Mastery @ProfHayward https://t.co/ICkaI5AhyD https://t.co/goHkcLpLqi https://t.co/BBjwC1tGH3 https://t.co/raGcSDQqay Not all of these are worth an hour or should change everything you do, but they add up to something.
RT @DrSsebo: A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy | NEJM https://t.co/hGfWMuyaqY
A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy | NEJM https://t.co/hGfWMuyaqY
妊娠初期の出血に対するプロゲステロン投与は、妊娠予後を改善しない https://t.co/2fcBDpw1PV
RT @ConryJeanne: Well designed study in NEJM for bleeding in early pregnancy: progesterone therapy did not result in higher live births tha…
Well designed study in NEJM for bleeding in early pregnancy: progesterone therapy did not result in higher live births than placebo. https://t.co/nBvotA93Sw
نشرت مجله NEJM الطبيه بحث يثبت ان إعطاء مثبت في حال وجود نزيف في الشهور الأولى من الحمل لا فائده له . #فضفضة_طبيب https://t.co/T2SDOMYT4j
RT @arricoomarasamy: 1/ PRISM Trial out in the NEJM! 54 extra babies with progesterone, 3% difference in live birth, borderline statistical…
https://t.co/lHoNIbxbDv
RT @MySMFM: Progesterone given for bleeding in early pregnancy does not increase chance of live birth The New England Journal of Medicine…
RT @NEJM: Original Article: A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy https://t.co/MbFFfuC809 Editorial…
RT @MySMFM: Progesterone given for bleeding in early pregnancy does not increase chance of live birth The New England Journal of Medicine…
RT @MySMFM: Progesterone given for bleeding in early pregnancy does not increase chance of live birth The New England Journal of Medicine…
RT @MySMFM: Progesterone given for bleeding in early pregnancy does not increase chance of live birth The New England Journal of Medicine…
RT @MySMFM: Progesterone given for bleeding in early pregnancy does not increase chance of live birth The New England Journal of Medicine…
RT @MySMFM: Progesterone given for bleeding in early pregnancy does not increase chance of live birth The New England Journal of Medicine…
Progesterone given for bleeding in early pregnancy does not increase chance of live birth The New England Journal of Medicine https://t.co/0SwHTwlKZC
A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy https://t.co/pxhkRaD39X
RT @NEJM: Miscarriage affects 1 in 5 pregnancies. Miscarriage can cause excessive bleeding, infection, and complications associated with su…
A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy https://t.co/Nn5oL76bXQ
RT @NEJM: Miscarriage affects 1 in 5 pregnancies. Miscarriage can cause excessive bleeding, infection, and complications associated with su…
RT @NEJM: Miscarriage affects 1 in 5 pregnancies. Miscarriage can cause excessive bleeding, infection, and complications associated with su…
RT @NEJM: Miscarriage affects 1 in 5 pregnancies. Miscarriage can cause excessive bleeding, infection, and complications associated with su…
RT @NEJM: Miscarriage affects 1 in 5 pregnancies. Miscarriage can cause excessive bleeding, infection, and complications associated with su…
RT @NEJM: Miscarriage affects 1 in 5 pregnancies. Miscarriage can cause excessive bleeding, infection, and complications associated with su…
RT @NEJM: Miscarriage affects 1 in 5 pregnancies. Miscarriage can cause excessive bleeding, infection, and complications associated with su…
RT @NEJM: Miscarriage affects 1 in 5 pregnancies. Miscarriage can cause excessive bleeding, infection, and complications associated with su…
RT @NEJM: Miscarriage affects 1 in 5 pregnancies. Miscarriage can cause excessive bleeding, infection, and complications associated with su…
RT @NEJM: Miscarriage affects 1 in 5 pregnancies. Miscarriage can cause excessive bleeding, infection, and complications associated with su…
RT @NEJM: Miscarriage affects 1 in 5 pregnancies. Miscarriage can cause excessive bleeding, infection, and complications associated with su…
RT @NEJM: Miscarriage affects 1 in 5 pregnancies. Miscarriage can cause excessive bleeding, infection, and complications associated with su…
RT @NEJM: Miscarriage affects 1 in 5 pregnancies. Miscarriage can cause excessive bleeding, infection, and complications associated with su…
RT @NEJM: Miscarriage affects 1 in 5 pregnancies. Miscarriage can cause excessive bleeding, infection, and complications associated with su…
RT @NEJM: Miscarriage affects 1 in 5 pregnancies. Miscarriage can cause excessive bleeding, infection, and complications associated with su…
RT @NEJM: Miscarriage affects 1 in 5 pregnancies. Miscarriage can cause excessive bleeding, infection, and complications associated with su…
Miscarriage affects 1 in 5 pregnancies. Miscarriage can cause excessive bleeding, infection, and complications associated with surgical treatment, as well as substantial psychological harm, including anxiety, depression, and PTSD. Learn more: https://t.co/MbFFfuTIRH
Progesterone supplementation in early pregnancy bleeding: the disappearing role of progesterone. @ANZSREI https://t.co/IFypJu7uSq
RT @2minmed: #VisualAbstract: A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy https://t.co/by2EHRzFSJ #StudyGr…
#VisualAbstract: A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy https://t.co/by2EHRzFSJ #StudyGraphics #bleedingduringpregnancy https://t.co/ncKochZjb1
RT @NEJM: Original Article: A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy https://t.co/MbFFfuC809 Editorial…
RT @arricoomarasamy: 1/ PRISM Trial out in the NEJM! 54 extra babies with progesterone, 3% difference in live birth, borderline statistical…
RT @arricoomarasamy: 1/ PRISM Trial out in the NEJM! 54 extra babies with progesterone, 3% difference in live birth, borderline statistical…
https://t.co/pIuB1F23sL
RT @NEJM: Original Article: A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy https://t.co/MbFFfuC809 Editorial…
RT @NEJM: Original Article: A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy https://t.co/MbFFfuC809 Editorial…
RT @NEJM: Original Article: A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy https://t.co/MbFFfuC809 Editorial…
RT @NEJM: #VisualAbstract: In this trial involving women with vaginal bleeding in early pregnancy, treatment with progesterone during the f…
RT @NEJM: Original Article: A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy https://t.co/MbFFfuC809 Editorial…
RT @NEJM: Original Article: A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy https://t.co/MbFFfuC809 Editorial…
RT @NEJM: Original Article: A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy https://t.co/MbFFfuC809 Editorial…
Original Article: A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy https://t.co/MbFFfuC809 Editorial: Progesterone for Threatened Abortion https://t.co/5JqXxAh2ST https://t.co/EssFdD65GZ
RT @NEJM: #VisualAbstract: In this trial involving women with vaginal bleeding in early pregnancy, treatment with progesterone during the f…
RT @NEJM: #VisualAbstract: In this trial involving women with vaginal bleeding in early pregnancy, treatment with progesterone during the f…
RT @arricoomarasamy: 1/ PRISM Trial out in the NEJM! 54 extra babies with progesterone, 3% difference in live birth, borderline statistical…
Sehr große und gut designte Studie zur Behandlung von Blutungen in der frühen Schwangerschaft. Progesteron hilft nur manchen. A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy https://t.co/Hz9h8T9WeU
RT @CMCPNEONATO: Progesterone in Women with Bleeding in Early Pregnancy https://t.co/G8FDFCvG69
Progesterone in Women with Bleeding in Early Pregnancy https://t.co/G8FDFCvG69
RT @arricoomarasamy: 1/ PRISM Trial out in the NEJM! 54 extra babies with progesterone, 3% difference in live birth, borderline statistical…
RT @NEJM: #VisualAbstract: In this trial involving women with vaginal bleeding in early pregnancy, treatment with progesterone during the f…
RT @arricoomarasamy: 1/ PRISM Trial out in the NEJM! 54 extra babies with progesterone, 3% difference in live birth, borderline statistical…
RT @NEJM: #VisualAbstract: In this trial involving women with vaginal bleeding in early pregnancy, treatment with progesterone during the f…
RT @arricoomarasamy: 1/ PRISM Trial out in the NEJM! 54 extra babies with progesterone, 3% difference in live birth, borderline statistical…
RT @NEJM: #VisualAbstract: In this trial involving women with vaginal bleeding in early pregnancy, treatment with progesterone during the f…
RT @NEJM: #VisualAbstract: In this trial involving women with vaginal bleeding in early pregnancy, treatment with progesterone during the f…
RT @NEJM: #VisualAbstract: In this trial involving women with vaginal bleeding in early pregnancy, treatment with progesterone during the f…
RT @NEJM: #VisualAbstract: In this trial involving women with vaginal bleeding in early pregnancy, treatment with progesterone during the f…
RT @NEJM: #VisualAbstract: In this trial involving women with vaginal bleeding in early pregnancy, treatment with progesterone during the f…
RT @NEJM: #VisualAbstract: In this trial involving women with vaginal bleeding in early pregnancy, treatment with progesterone during the f…
RT @NEJM: #VisualAbstract: In this trial involving women with vaginal bleeding in early pregnancy, treatment with progesterone during the f…
RT @NEJM: #VisualAbstract: In this trial involving women with vaginal bleeding in early pregnancy, treatment with progesterone during the f…
RT @NEJM: #VisualAbstract: In this trial involving women with vaginal bleeding in early pregnancy, treatment with progesterone during the f…
RT @NEJM: #VisualAbstract: In this trial involving women with vaginal bleeding in early pregnancy, treatment with progesterone during the f…
RT @NEJM: #VisualAbstract: In this trial involving women with vaginal bleeding in early pregnancy, treatment with progesterone during the f…
RT @NEJM: #VisualAbstract: In this trial involving women with vaginal bleeding in early pregnancy, treatment with progesterone during the f…
RT @NEJM: #VisualAbstract: In this trial involving women with vaginal bleeding in early pregnancy, treatment with progesterone during the f…
RT @NEJM: #VisualAbstract: In this trial involving women with vaginal bleeding in early pregnancy, treatment with progesterone during the f…
RT @NEJM: #VisualAbstract: In this trial involving women with vaginal bleeding in early pregnancy, treatment with progesterone during the f…
RT @NEJM: #VisualAbstract: In this trial involving women with vaginal bleeding in early pregnancy, treatment with progesterone during the f…
RT @NEJM: #VisualAbstract: In this trial involving women with vaginal bleeding in early pregnancy, treatment with progesterone during the f…
RT @NEJM: #VisualAbstract: In this trial involving women with vaginal bleeding in early pregnancy, treatment with progesterone during the f…
RT @NEJM: #VisualAbstract: In this trial involving women with vaginal bleeding in early pregnancy, treatment with progesterone during the f…
RT @NEJM: #VisualAbstract: In this trial involving women with vaginal bleeding in early pregnancy, treatment with progesterone during the f…
RT @NEJM: #VisualAbstract: In this trial involving women with vaginal bleeding in early pregnancy, treatment with progesterone during the f…
#VisualAbstract: In this trial involving women with vaginal bleeding in early pregnancy, treatment with progesterone during the first trimester did not result in a significantly higher incidence of live births than placebo. Full abstract: https://t.co/MbFFfuC809
Everyone is doing this even without a significant benefit... Just like what I am doing everyday... https://t.co/hPyhjJj9sb
RT @francescakinse3: Bravo @adam_devall and co- a great team effort!..... A Randomized Trial of Progesterone in Women with Bleeding in Ea…
A randomized trial of progesterone in women with bleeding in early pregnancy https://t.co/tb3JGotzPk #pharmacists #pharmacy #healthcare #health #profession
A randomized trial of progesterone in women with bleeding in early pregnancy https://t.co/dpQy5Ng0Ir #pharmacists #pharmacy #health #healthcare
Bravo @adam_devall and co- a great team effort!..... A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy | NEJM.... @UoB_MDSRKTO @Tommys_baby @bablakeformerp1 https://t.co/Z6vc0eNl2B
A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy. https://t.co/Xg8j5A5l5B
A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy | NEJM https://t.co/2bzutH2von
A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy | NEJM https://t.co/dY4BUG36W5
A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy | NEJM https://t.co/Gk0TqpWVnV
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