PubHawk
Schmerz October 2019 PMID 31073761

Efficacy, tolerability and safety of cannabis-based medicines for cancer pain : A systematic review with meta-analysis of randomised controlled trials.

Winfried Häuser, Patrick Welsch, Petra Klose, Lukas Radbruch, Mary-Ann Fitzcharles

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Mentions

43
Peak: 20 in May 2019
across 4 sources since May 2019

Extended reach

121,327
potential audience

Total likes

790

Video views

11,807

Mentions per month

May 2019 – Oct 2025

Where it's discussed

  • X / Twitter35 posts
  • News4 articles
  • YouTube2 videos
  • Facebook2 posts

AI synopsis

What people are saying

Discussions around the publication often include critical comments about the low quality of evidence, with phrases like 'very low quality evidence suggests' and 'no effect on pain,' illustrating skepticism and highlighting the inconclusive nature of the research. The tone varies from cautious curiosity to dismissiveness, reflecting mixed perceptions of the article’s significance and the current state of evidence in this field.

AgreementLow agreement

Most posts highlight that evidence for cannabis-based medicines in cancer pain management is limited or shows no significant benefits, reflecting skepticism or disagreement with claims of efficacy.

InterestModerate interest

Several discussions express curiosity about the research findings, referencing phrases like 'new on' or 'results of a study,' indicating moderate interest in the topic.

EngagementModerate engagement

A few posts critically analyze study quality or mention bias and methodology, demonstrating some deeper engagement, but overall comments are surface-level.

ImpactLow impact

Many posts suggest the findings have minimal impact on treatment practices yet emphasize the importance of ongoing research, indicating a perception of limited immediate influence.

Abstract in brief

  • This review evaluates the effectiveness and safety of cannabis-based medicines like nabiximols and THC for managing cancer pain, especially for patients who don't get enough relief from opioids.
  • The analysis included five high-quality RCTs with around 1,534 participants, but found that these medicines did not significantly outperform placebo in reducing pain, improving sleep, or decreasing opioid use, and evidence quality was very low.
  • While more patients reported feeling much improved with these treatments, there was no significant difference in adverse effects or serious side effects compared to placebo, but overall, the evidence is limited, meaning more research is needed to fully understand their benefits and risks.]
Read the full abstract

Top posts

Most liked on X and Bluesky
Bertha madras
@madras_bertha · X

Efficacy, tolerability and safety of cannabis-based medicines for cancer pain : A systematic review with meta-analysis of randomised controlled trial... - PubMed - NCBI. No efficacy https://t.co/MWfM26tL5J

May 15, 2019 · 3 likes · 5 shares · 2,834 followers View post →
Bertha madras
@madras_bertha · X

Efficacy, tolerability and safety of cannabis-based medicines for cancer pain : A systematic review with meta-analysis of randomised controlled trial... - PubMed - NCBI https://t.co/MWfM26LlXh

Sep 20, 2019 · 3 likes · 4 shares · 2,834 followers View post →
MLP Oncología
@MLPOncoData · X

Efficacy, tolerability and safety of cannabis-based medicines for cancer pain: oromucosal nabiximols and THC have no effect on pain, sleep problems and opioid consumption in patients with cancer pain with insufficient pain relief from opioids. https://t.co/OvycSLFyiR

Oct 11, 2019 · 1 like · 709 followers View post →
Cannabis Risk Alliance
@MythsCannabis · X

Efficacy, tolerability and safety of cannabis-based medicines for cancer pain : A systematic review with meta-analysis of randomised controlled tri... - PubMed - NCBI Evidence shows little benefit for cancer pain use https://t.co/FatFeFdwyV

May 19, 2019 · 1 like · 3 shares · 519 followers View post →
Margaret “Meg” Chisolm, MD
@whole_patients · X

RT @madras_bertha: Efficacy, tolerability and safety of cannabis-based medicines for cancer pain : A systematic review with meta-analysis o…

Sep 21, 2019 · 4 shares · 8,254 followers View post →
Ray Walley
@WalleyRay · X

RT @madras_bertha: Efficacy, tolerability and safety of cannabis-based medicines for cancer pain : A systematic review with meta-analysis o…

May 26, 2019 · 5 shares · 7,497 followers View post →

All mentions

roque furtado
@errefurtado · X

>>>|DESESTIGMATIZE A MACONHA... https://t.co/7os4LrYGE0

May 23, 2025 · 761 followers View post →
KFinn, MD
@CoDoc442 · X

@melrod42 Very low quality evidence suggests that oromucosal nabiximols and THC have no effect on pain, sleep problems and opioid consumption in patients with cancer pain with insufficient pain relief from opioids. https://t.co/U1OVwjSMX5

Nov 23, 2021 · 1,331 followers View post →
Hannes Carlsson
@haecarlsson · X

@AmirEnglund @sweportia @Bulletin_Nu Kritik mot hur de hanterade bias i kommentar till artikeln. Och tyvärr inte bättre läge för cancersmärta https://t.co/6VHyz7WNbg

Mar 20, 2021 · 54 followers View post →
serotonin_nin
@serotonin_nin · X

Results of a Double-Blind, Randomized, Placebo-Controlled Study of Nabiximols Oromucosal Spray as an Adjunctive Therapy in Advanced Cancer https://t.co/fw1HibWgVW Efficacy, tolerability and safety of cannabis-based medicines for cancer pain https://t.co/4BnfIGkdL2

Feb 23, 2020 · 2,373 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @Info4Practice: New on https://t.co/8pxKdRDxAR | Efficacy, tolerability and safety of cannabis-based medicines for cancer pain : A syste…

Oct 25, 2019 · 1 share · 6,704 followers View post →
MLP Oncología
@MLPOncoData · X

Efficacy, tolerability and safety of cannabis-based medicines for cancer pain: oromucosal nabiximols and THC have no effect on pain, sleep problems and opioid consumption in patients with cancer pain with insufficient pain relief from opioids. https://t.co/OvycSLFyiR

Oct 11, 2019 · 1 like · 709 followers View post →
Cancer Library VCC
@VCCLibrary · X

RT @palliativewise: Efficacy, tolerability and safety of cannabis-based medicines for cancer pain : A systematic review with meta-analysis…

Oct 8, 2019 · 2 shares · 1,273 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @palliativewise: Efficacy, tolerability and safety of cannabis-based medicines for cancer pain : A systematic review with meta-analysis…

Oct 8, 2019 · 2 shares · 6,704 followers View post →
palliativewise
@palliativewise · X

Efficacy, tolerability and safety of cannabis-based medicines for cancer pain : A systematic review with meta-analysis of randomised controlled trials. https://t.co/PErWAj9oKF

Oct 8, 2019 · 2 shares · 380 followers View post →
painmanwise
@painmanwise · X

Efficacy, tolerability and safety of cannabis-based medicines for cancer pain : A systematic review with meta-analysis of randomised controlled trials. https://t.co/Ol2Fg50dHv

Oct 8, 2019 · 225 followers View post →
Katja Pihlainen
@KatjaPihlainen · X

RT @madras_bertha: Efficacy, tolerability and safety of cannabis-based medicines for cancer pain : A systematic review with meta-analysis o…

Sep 22, 2019 · 4 shares · 230 followers View post →
Margaret “Meg” Chisolm, MD
@whole_patients · X

RT @madras_bertha: Efficacy, tolerability and safety of cannabis-based medicines for cancer pain : A systematic review with meta-analysis o…

Sep 21, 2019 · 4 shares · 8,254 followers View post →
Ray Walley
@WalleyRay · X

RT @madras_bertha: Efficacy, tolerability and safety of cannabis-based medicines for cancer pain : A systematic review with meta-analysis o…

Sep 20, 2019 · 4 shares · 7,497 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @madras_bertha: Efficacy, tolerability and safety of cannabis-based medicines for cancer pain : A systematic review with meta-analysis o…

Sep 20, 2019 · 4 shares · 6,704 followers View post →
Bertha madras
@madras_bertha · X

Efficacy, tolerability and safety of cannabis-based medicines for cancer pain : A systematic review with meta-analysis of randomised controlled trial... - PubMed - NCBI https://t.co/MWfM26LlXh

Sep 20, 2019 · 3 likes · 4 shares · 2,834 followers View post →
Ray Walley
@WalleyRay · X

RT @madras_bertha: Efficacy, tolerability and safety of cannabis-based medicines for cancer pain : A systematic review with meta-analysis o…

May 26, 2019 · 5 shares · 7,497 followers View post →
TANAMAHASAMA
@t_patima · X

RT @MythsCannabis: Efficacy, tolerability and safety of cannabis-based medicines for cancer pain : A systematic review with meta-analysis o…

May 19, 2019 · 3 shares · 55 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @MythsCannabis: Efficacy, tolerability and safety of cannabis-based medicines for cancer pain : A systematic review with meta-analysis o…

May 19, 2019 · 3 shares · 6,704 followers View post →
Gordon MRM
@gordon_mrm · X

RT @MythsCannabis: Efficacy, tolerability and safety of cannabis-based medicines for cancer pain : A systematic review with meta-analysis o…

May 19, 2019 · 3 shares · 1,522 followers View post →
Cannabis Risk Alliance
@MythsCannabis · X

Efficacy, tolerability and safety of cannabis-based medicines for cancer pain : A systematic review with meta-analysis of randomised controlled tri... - PubMed - NCBI Evidence shows little benefit for cancer pain use https://t.co/FatFeFdwyV

May 19, 2019 · 1 like · 3 shares · 519 followers View post →
CARLOS TABARES
@carlostabarespa · X

Efficacy, tolerability and safety of cannabis-based medicines for cancer pain: https://t.co/QcrXyu4fVz

May 17, 2019 · 383 followers View post →
C
@SocialJustice4A · X

RT @madras_bertha: Efficacy, tolerability and safety of cannabis-based medicines for cancer pain : A systematic review with meta-analysis o…

May 16, 2019 · 5 shares · 950 followers View post →
AALM
@SupportAALM · X

RT @madras_bertha: Efficacy, tolerability and safety of cannabis-based medicines for cancer pain : A systematic review with meta-analysis o…

May 15, 2019 · 5 shares · 482 followers View post →
Ali Farhoudian
@farhoudian · X

RT @madras_bertha: Efficacy, tolerability and safety of cannabis-based medicines for cancer pain : A systematic review with meta-analysis o…

May 15, 2019 · 5 shares · 673 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @madras_bertha: Efficacy, tolerability and safety of cannabis-based medicines for cancer pain : A systematic review with meta-analysis o…

May 15, 2019 · 5 shares · 6,704 followers View post →
Bertha madras
@madras_bertha · X

Efficacy, tolerability and safety of cannabis-based medicines for cancer pain : A systematic review with meta-analysis of randomised controlled trial... - PubMed - NCBI. No efficacy https://t.co/MWfM26tL5J

May 15, 2019 · 3 likes · 5 shares · 2,834 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @ZeBepsMD: "Efficacy, tolerability and safety of #cannabis-based medicines for #cancer #pain: a systematic review with meta-analysis of…

May 12, 2019 · 1 share · 6,704 followers View post →
♫ Ze Beps, MD ♫
@ZeBepsMD · X

"Efficacy, tolerability and safety of #cannabis-based medicines for #cancer #pain: a systematic review with meta-analysis of randomised controlled trials" #hpm #palliativecare https://t.co/w3hfUg7FH9 https://t.co/tdGypyvNAd

May 12, 2019 · 1 share · 412 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @Ingentium_Inc: Efficacy, tolerability and safety of cannabis-based medicines for #cancer pain : A systematic review with meta-analysis…

May 11, 2019 · 1 share · 6,704 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @NNTonthefly: New NNT→Efficacy, tolerability and safety of cannabis-based medicines for cancer pain : A systematic review with meta-anal…

May 11, 2019 · 1 share · 6,704 followers View post →
NNTonthefly
@NNTonthefly · X

New NNT→Efficacy, tolerability and safety of cannabis-based medicines for cancer pain : A systematic review with meta-analysis of randomised controlled trials. https://t.co/JLv7jm6JMC

May 11, 2019 · 1 share · 472 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @palliativewise: Efficacy, tolerability and safety of cannabis-based medicines for cancer pain : A systematic review with meta-analysis…

May 11, 2019 · 1 share · 6,704 followers View post →
palliativewise
@palliativewise · X

Efficacy, tolerability and safety of cannabis-based medicines for cancer pain : A systematic review with meta-analysis of randomised controlled trials. https://t.co/PErWAj9oKF

May 11, 2019 · 1 share · 380 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @painmanwise: Efficacy, tolerability and safety of cannabis-based medicines for cancer pain : A systematic review with meta-analysis of…

May 11, 2019 · 1 share · 6,704 followers View post →
painmanwise
@painmanwise · X

Efficacy, tolerability and safety of cannabis-based medicines for cancer pain : A systematic review with meta-analysis of randomised controlled trials. https://t.co/ixo5PqypZx

May 11, 2019 · 1 share · 225 followers View post →