スタチンの延命効果 Postponement of Death by Statin Use: a Systematic Review and Meta-analysis of Randomized Clinical Trials. - PubMed - NCBI https://t.co/zZ8zQTJ6ep
Postponement of Death by Statin Use: a Systematic Review and Meta-analysis of Randomized Clinical Trials.
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May 2019 – Oct 2025Where it's discussed
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X / Twitter27 posts
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YouTube2 videos
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What people are saying
The overall tone reflects serious analysis of the article's findings, with examples like mentions of '13 days' or '10 days' in life expectancy gains, and debates over their significance. Words like 'negligible,' 'small,' and 'paradox' reveal a tone of skepticism but also curiosity about how such data affects clinical decisions, illustrating moderate engagement with the implications of the research.
Most discussions are skeptical or neutral about the significance of the findings, emphasizing small gains rather than outright disagreement.
The discussions focus on the small but measurable effects of statins, indicating high curiosity and concern about medical impact.
Posts reference various studies, numbers, and interpretations, showing moderate to thoughtful discussion rather than superficial remarks.
While highlighting small effect sizes, some posts suggest that even modest survival gains are meaningful, implying moderate influence on perspectives.
Abstract in brief
- The average postponement of health outcomes due to preventive medications, particularly statins, may be a more intuitive measure than traditional metrics like number needed to treat.
- A new meta-analysis of statin trials indicated an average outcome postponement for all-cause mortality of 12.6 days, with variations based on the type of trial: 10.2 days for primary prevention, 17.4 days for secondary prevention, and 8.5 days for mixed prevention.
- This approach highlights the potential benefits of preventive treatments in a way that is more accessible for patients and communicates the small increase in survival time effectively.
Top posts
Most liked on X and BlueskyDon't be fooled by the lies "For primary, secondary, and mixed prevention trials, respectively, outcome postponements were 10.2 days (PI, 4.0–16.3), 17.4 days (PI, 6.0–28.8), and 8.5 days (PI, 1.9–15.0)" https://t.co/IqdRhBV9yG https://t.co/H1VRGVhJph
This meta-analysis of 16 trials and 103,680 patients demonstrates that taking statins result in an overall gain in life expectancy of 13 days on average, over 5 years of trial duration. @mortenrhansen https://t.co/5O0HtJPkKw https://t.co/eu9rpEfV0w
@nicknorwitz Save lives takes on a different meaning when you out numbers to it: 10.2 and 17.4 days for primary and secondary prevention, respectively, once normalized to a 5-year period https://t.co/O5xBqi1cj8
Outcome postponement -a new way to measure impact of a preventive medication. Review of previous trials => #Statins postpone primary outcome by <20 days! @JournalGIM https://t.co/bDFbmZbPZn
@holmanm @HototDwarf @steveroedde @LDLSkeptic @MaryanneDemasi @pbyrne82 @drjohnm @susanmsmith @FatEmperor @DiscoStew66 @KenDBerryMD @IMWHorvitz @ifixhearts @Mangan150 @dramerling @markeatsmeat what do you think of this Marion? https://t.co/IqdRhBV9yG "The median modeled outcome postponement was 10.0 days (interquartile range, 2.9–19.5 days)"
All mentions
Evaluating the Actual Life Extension from Statin Use
Is it true statins only delay your death by 3 DAYS? This video reviews current research indicating that, on average, statins may postpone death by around 12.6 days, emphasizing a nuanced understanding of their benefits…
Evaluating the Actual Benefits of Cholesterol and Statin Prevention
This video discusses the controversy surrounding cholesterol, its health risks, and benefits. It reviews scientific studies, the impact of factors like LDL subclasses, and the effectiveness of statins, highlighting how…
@nicknorwitz Save lives takes on a different meaning when you out numbers to it: 10.2 and 17.4 days for primary and secondary prevention, respectively, once normalized to a 5-year period https://t.co/O5xBqi1cj8
RT @raphaels7: Don't be fooled by the lies "For primary, secondary, and mixed prevention trials, respectively, outcome postponements were…
Don't be fooled by the lies "For primary, secondary, and mixed prevention trials, respectively, outcome postponements were 10.2 days (PI, 4.0–16.3), 17.4 days (PI, 6.0–28.8), and 8.5 days (PI, 1.9–15.0)" https://t.co/IqdRhBV9yG https://t.co/H1VRGVhJph
@JohnTho55144371 @MichelleZeh1968 @OhNoDano @Mand2101 @ProfDuckDuckGo @IMudlet @Veeteejay1 @PenOfAPisces @JimeeLiberty @DocDeezWhat @nopoisonjabs @CarlSmytheCells @DoubleDumas @1984rebooted @SapoVerdeSalsa @ThomMohr @ImAtSeaAgain @JesperKitos @dirk_fasshauer @cnv_cnvl @LummHandy @TakethatCt @ticklemepfizer1 @Hops_Mead @ScooterScience @JRJHealey @JSanders174 @DdkDav @SabinehazanMD @0IiI______oO @DiscernHeal @HamHead5813 @djchicus @L__instigateur @DR_WRATHBERG @DavidLMayhew @paramaniac9 @ValZimmer2 @hauxton @ZeroPointV1 @catsequalneko @dan_gadd @pjholloway @PamelaE83716920 @SynthIge @BoyScou84038220 @OB1_Benobie @ONS You can't really argue with a reduction in all cause mortality with that argument https://t.co/elm5JnpXVO https://t.co/LepoEDcigj https://t.co/o9tSK5K9NC
@holmanm @HototDwarf @steveroedde @LDLSkeptic @MaryanneDemasi @pbyrne82 @drjohnm @susanmsmith @FatEmperor @DiscoStew66 @KenDBerryMD @IMWHorvitz @ifixhearts @Mangan150 @dramerling @markeatsmeat what do you think of this Marion? https://t.co/IqdRhBV9yG "The median modeled outcome postponement was 10.0 days (interquartile range, 2.9–19.5 days)"
@Meda78263550 @Mangan150 https://t.co/tLJZU7ENW5
@raphaels7 @Lpa_Doc How do you read that? I can't believe the difference can be measured in days. Though it seems pretty common: https://t.co/lKufrN45Xa https://t.co/KkUeC1vaLv
8/ In some situations, large event reduction matches large survival gains. But in others, especially in the elderly, event reduction may translate to more modest survival gains. https://t.co/SY3SUyJtkv
12.6 day increase in longevity with Statins https://t.co/8rAojmZqPm
A systematic review and meta-analysis of randomized clinical trials involving patients prescribed statins for many years concluded that their survival was increased by only 10 days! https://t.co/HEaxS3sCEn
@adamcifu Perhaps your patients were excellently informed on long term statin benefits of only a few days. https://t.co/6suQHYaNqK https://t.co/HEaxS3sCEn https://t.co/ngDVihw4WD
RT @NNTonthefly: New NNT→Postponement of Death by Statin Use: a Systematic Review and Meta-analysis of Randomized Clinical Trials. https://…
New NNT→Postponement of Death by Statin Use: a Systematic Review and Meta-analysis of Randomized Clinical Trials. https://t.co/QzreUpNLLw
“The median modeled outcome postponement was 10.0 days” https://t.co/06HTSHZYQR
@HL327 @ProfHayward @stephensenn @f2harrell @hmkyale @mgtmccartney @medmyths @raymoynihan Here is a neat example of looking at survival gains rather than event reduction. It's an odd paradox that as we get older, events are more common but gains of preventing them diminish. https://t.co/bKbJxE06nf
RT @syuichiao89: スタチンの延命効果 Postponement of Death by Statin Use: a Systematic Review and Meta-analysis of Randomized Clinical Trials. - Pub…
スタチンの延命効果 Postponement of Death by Statin Use: a Systematic Review and Meta-analysis of Randomized Clinical Trials. - PubMed - NCBI https://t.co/zZ8zQTJ6ep
RT @ggimenezendocri: Meta-analysis of 16 trials and 103,680 patients demonstrates that taking statins result in an overall gain in life exp…
RT @ggimenezendocri: Meta-analysis of 16 trials and 103,680 patients demonstrates that taking statins result in an overall gain in life exp…
Meta-analysis of 16 trials and 103,680 patients demonstrates that taking statins result in an overall gain in life expectancy of 13 days on average, over 5 years of trial duration. https://t.co/M9waf9l82q
RT @JournalGIM: This meta-analysis of 16 trials and 103,680 patients demonstrates that taking statins result in an overall gain in life exp…
RT @JournalGIM: This meta-analysis of 16 trials and 103,680 patients demonstrates that taking statins result in an overall gain in life exp…
This meta-analysis of 16 trials and 103,680 patients demonstrates that taking statins result in an overall gain in life expectancy of 13 days on average, over 5 years of trial duration. @mortenrhansen https://t.co/5O0HtJPkKw https://t.co/eu9rpEfV0w
Outcome postponement -a new way to measure impact of a preventive medication. Review of previous trials => #Statins postpone primary outcome by <20 days! @JournalGIM https://t.co/bDFbmZbPZn
RT @JournalGIM: Postponement of Death by Statin Use: a Systematic Review and Meta-analysis of Randomized Clinical Trials https://t.co/rfSfu…
RT @JournalGIM: Postponement of Death by Statin Use: a Systematic Review and Meta-analysis of Randomized Clinical Trials https://t.co/rfSfu…
Postponement of Death by Statin Use: a Systematic Review and Meta-analysis of Randomized Clinical Trials https://t.co/rfSfurKsQP
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