J Gen Intern Med August 2019 PMID 31073857

Postponement of Death by Statin Use: a Systematic Review and Meta-analysis of Randomized Clinical Trials.

Morten Rix Hansen, Asbjørn Hróbjartsson, Anton Pottegård, Per Damkier, Kasper Søltoft Larsen, Kenneth Grønkjær Madsen, René dePont Christensen, Malene Elisa Lopez Kristensen, Palle Mark Christensen, Jesper Hallas

Mentions

31
Peak: 10 in May 2019
across 3 sources since May 2019

Extended reach

172,661
potential audience

Total likes

2,526

Video views

51,906

Mentions per month

May 2019 – Oct 2025

Where it's discussed

  • X / Twitter27 posts
  • YouTube2 videos
  • Blogs2 articles

AI synopsis

What people are saying

The overall tone reflects serious analysis of the article's findings, with examples like mentions of '13 days' or '10 days' in life expectancy gains, and debates over their significance. Words like 'negligible,' 'small,' and 'paradox' reveal a tone of skepticism but also curiosity about how such data affects clinical decisions, illustrating moderate engagement with the implications of the research.

AgreementNeither agree nor disagree

Most discussions are skeptical or neutral about the significance of the findings, emphasizing small gains rather than outright disagreement.

InterestHigh interest

The discussions focus on the small but measurable effects of statins, indicating high curiosity and concern about medical impact.

EngagementModerate engagement

Posts reference various studies, numbers, and interpretations, showing moderate to thoughtful discussion rather than superficial remarks.

ImpactModerate impact

While highlighting small effect sizes, some posts suggest that even modest survival gains are meaningful, implying moderate influence on perspectives.

Abstract in brief

  • The average postponement of health outcomes due to preventive medications, particularly statins, may be a more intuitive measure than traditional metrics like number needed to treat.
  • A new meta-analysis of statin trials indicated an average outcome postponement for all-cause mortality of 12.6 days, with variations based on the type of trial: 10.2 days for primary prevention, 17.4 days for secondary prevention, and 8.5 days for mixed prevention.
  • This approach highlights the potential benefits of preventive treatments in a way that is more accessible for patients and communicates the small increase in survival time effectively.

Top posts

Most liked on X and Bluesky
青島周一@【書籍】「生成AIと学ぶ医学論文の読み方・考え方」発売中!
@syuichiao89 · X

スタチンの延命効果 Postponement of Death by Statin Use: a Systematic Review and Meta-analysis of Randomized Clinical Trials. - PubMed - NCBI https://t.co/zZ8zQTJ6ep

Oct 3, 2019 · 9 likes · 1 share · 8,611 followers View post →
Raphael Sirtoli
@raphaels7 · X

Don't be fooled by the lies "For primary, secondary, and mixed prevention trials, respectively, outcome postponements were 10.2 days (PI, 4.0–16.3), 17.4 days (PI, 6.0–28.8), and 8.5 days (PI, 1.9–15.0)" https://t.co/IqdRhBV9yG https://t.co/H1VRGVhJph

Apr 29, 2024 · 6 likes · 1 share · 8,596 followers View post →
JGIM Journal of General Internal Medicine
@JournalGIM · X

This meta-analysis of 16 trials and 103,680 patients demonstrates that taking statins result in an overall gain in life expectancy of 13 days on average, over 5 years of trial duration. @mortenrhansen https://t.co/5O0HtJPkKw https://t.co/eu9rpEfV0w

May 21, 2019 · 3 likes · 3 shares · 8,747 followers View post →
Raphael Sirtoli
@raphaels7 · X

@nicknorwitz Save lives takes on a different meaning when you out numbers to it: 10.2 and 17.4 days for primary and secondary prevention, respectively, once normalized to a 5-year period https://t.co/O5xBqi1cj8

Oct 3, 2025 · 3 likes · 8,596 followers View post →
Neil
@Neil_Mehta · X

Outcome postponement -a new way to measure impact of a preventive medication. Review of previous trials => #Statins postpone primary outcome by <20 days! ⁦@JournalGIM⁩ https://t.co/bDFbmZbPZn

May 12, 2019 · 3 likes · 5,689 followers View post →
Raphael Sirtoli
@raphaels7 · X

@holmanm @HototDwarf @steveroedde @LDLSkeptic @MaryanneDemasi @pbyrne82 @drjohnm @susanmsmith @FatEmperor @DiscoStew66 @KenDBerryMD @IMWHorvitz @ifixhearts @Mangan150 @dramerling @markeatsmeat what do you think of this Marion? https://t.co/IqdRhBV9yG "The median modeled outcome postponement was 10.0 days (interquartile range, 2.9–19.5 days)"

Oct 18, 2023 · 2 likes · 8,596 followers View post →

All mentions

Raphael Sirtoli
@raphaels7 · X

@nicknorwitz Save lives takes on a different meaning when you out numbers to it: 10.2 and 17.4 days for primary and secondary prevention, respectively, once normalized to a 5-year period https://t.co/O5xBqi1cj8

Oct 3, 2025 · 3 likes · 8,596 followers View post →
Tony Scott
@DIY_Tardis · X

RT @raphaels7: Don't be fooled by the lies "For primary, secondary, and mixed prevention trials, respectively, outcome postponements were…

Apr 29, 2024 · 1 share · 1,723 followers View post →
Raphael Sirtoli
@raphaels7 · X

Don't be fooled by the lies "For primary, secondary, and mixed prevention trials, respectively, outcome postponements were 10.2 days (PI, 4.0–16.3), 17.4 days (PI, 6.0–28.8), and 8.5 days (PI, 1.9–15.0)" https://t.co/IqdRhBV9yG https://t.co/H1VRGVhJph

Apr 29, 2024 · 6 likes · 1 share · 8,596 followers View post →
Martin Phosphorus
@Tetrahydropyran · X

@JohnTho55144371 @MichelleZeh1968 @OhNoDano @Mand2101 @ProfDuckDuckGo @IMudlet @Veeteejay1 @PenOfAPisces @JimeeLiberty @DocDeezWhat @nopoisonjabs @CarlSmytheCells @DoubleDumas @1984rebooted @SapoVerdeSalsa @ThomMohr @ImAtSeaAgain @JesperKitos @dirk_fasshauer @cnv_cnvl @LummHandy @TakethatCt @ticklemepfizer1 @Hops_Mead @ScooterScience @JRJHealey @JSanders174 @DdkDav @SabinehazanMD @0IiI______oO @DiscernHeal @HamHead5813 @djchicus @L__instigateur @DR_WRATHBERG @DavidLMayhew @paramaniac9 @ValZimmer2 @hauxton @ZeroPointV1 @catsequalneko @dan_gadd @pjholloway @PamelaE83716920 @SynthIge @BoyScou84038220 @OB1_Benobie @ONS You can't really argue with a reduction in all cause mortality with that argument https://t.co/elm5JnpXVO https://t.co/LepoEDcigj https://t.co/o9tSK5K9NC

Nov 18, 2023 · 118 followers View post →
Raphael Sirtoli
@raphaels7 · X

@holmanm @HototDwarf @steveroedde @LDLSkeptic @MaryanneDemasi @pbyrne82 @drjohnm @susanmsmith @FatEmperor @DiscoStew66 @KenDBerryMD @IMWHorvitz @ifixhearts @Mangan150 @dramerling @markeatsmeat what do you think of this Marion? https://t.co/IqdRhBV9yG "The median modeled outcome postponement was 10.0 days (interquartile range, 2.9–19.5 days)"

Oct 18, 2023 · 2 likes · 8,596 followers View post →
Eric Cowger
@eolecow3 · X

@Meda78263550 @Mangan150 https://t.co/tLJZU7ENW5

Jun 25, 2023 · 1 like · 143 followers View post →
mr. pink
@lcmail2 · X

@raphaels7 @Lpa_Doc How do you read that? I can't believe the difference can be measured in days. Though it seems pretty common: https://t.co/lKufrN45Xa https://t.co/KkUeC1vaLv

Jan 10, 2023 · 158 followers View post →
Raj Mehta
@raj_mehta · X

8/ In some situations, large event reduction matches large survival gains. But in others, especially in the elderly, event reduction may translate to more modest survival gains. https://t.co/SY3SUyJtkv

Jun 14, 2022 · 2,132 followers View post →
Afraz Zaman
@Afrazzaman · X

12.6 day increase in longevity with Statins https://t.co/8rAojmZqPm

Apr 24, 2021 · 209 followers View post →
Stavros Saripanidis, MD
@DrSaripanidis · X

A systematic review and meta-analysis of randomized clinical trials involving patients prescribed statins for many years concluded that their survival was increased by only 10 days! https://t.co/HEaxS3sCEn

Feb 25, 2021 · 689 followers View post →
Stavros Saripanidis, MD
@DrSaripanidis · X

@adamcifu Perhaps your patients were excellently informed on long term statin benefits of only a few days. https://t.co/6suQHYaNqK https://t.co/HEaxS3sCEn https://t.co/ngDVihw4WD

Feb 25, 2021 · 2 likes · 689 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @NNTonthefly: New NNT→Postponement of Death by Statin Use: a Systematic Review and Meta-analysis of Randomized Clinical Trials. https://…

Nov 5, 2020 · 1 share · 6,704 followers View post →
NNTonthefly
@NNTonthefly · X

New NNT→Postponement of Death by Statin Use: a Systematic Review and Meta-analysis of Randomized Clinical Trials. https://t.co/QzreUpNLLw

Nov 5, 2020 · 1 share · 472 followers View post →
DiscoStew
@DiscoStew66 · X

“The median modeled outcome postponement was 10.0 days” https://t.co/06HTSHZYQR

Sep 11, 2020 · 1 like · 1 share · 10,790 followers View post →
Raj Mehta
@raj_mehta · X

@HL327 @ProfHayward @stephensenn @f2harrell @hmkyale @mgtmccartney @medmyths @raymoynihan Here is a neat example of looking at survival gains rather than event reduction. It's an odd paradox that as we get older, events are more common but gains of preventing them diminish. https://t.co/bKbJxE06nf

Aug 14, 2020 · 1 like · 2,132 followers View post →
☫кептагоп™Я☫
@kentaron1971 · X

RT @syuichiao89: スタチンの延命効果 Postponement of Death by Statin Use: a Systematic Review and Meta-analysis of Randomized Clinical Trials. - Pub…

Oct 3, 2019 · 1 share · 12,475 followers View post →
青島周一@【書籍】「生成AIと学ぶ医学論文の読み方・考え方」発売中!
@syuichiao89 · X

スタチンの延命効果 Postponement of Death by Statin Use: a Systematic Review and Meta-analysis of Randomized Clinical Trials. - PubMed - NCBI https://t.co/zZ8zQTJ6ep

Oct 3, 2019 · 9 likes · 1 share · 8,611 followers View post →
Andreu Nubiola
@Anubiolac · X

RT @ggimenezendocri: Meta-analysis of 16 trials and 103,680 patients demonstrates that taking statins result in an overall gain in life exp…

May 22, 2019 · 2 shares · 450 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @ggimenezendocri: Meta-analysis of 16 trials and 103,680 patients demonstrates that taking statins result in an overall gain in life exp…

May 22, 2019 · 2 shares · 6,704 followers View post →
Gabriel Gimenez MD
@ggimenezendocri · X

Meta-analysis of 16 trials and 103,680 patients demonstrates that taking statins result in an overall gain in life expectancy of 13 days on average, over 5 years of trial duration. https://t.co/M9waf9l82q

May 22, 2019 · 2 likes · 2 shares · 523 followers View post →
Gabriel Gimenez MD
@ggimenezendocri · X

RT @JournalGIM: This meta-analysis of 16 trials and 103,680 patients demonstrates that taking statins result in an overall gain in life exp…

May 21, 2019 · 3 shares · 523 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @JournalGIM: This meta-analysis of 16 trials and 103,680 patients demonstrates that taking statins result in an overall gain in life exp…

May 21, 2019 · 3 shares · 6,704 followers View post →
JGIM Journal of General Internal Medicine
@JournalGIM · X

This meta-analysis of 16 trials and 103,680 patients demonstrates that taking statins result in an overall gain in life expectancy of 13 days on average, over 5 years of trial duration. @mortenrhansen https://t.co/5O0HtJPkKw https://t.co/eu9rpEfV0w

May 21, 2019 · 3 likes · 3 shares · 8,747 followers View post →
Neil
@Neil_Mehta · X

Outcome postponement -a new way to measure impact of a preventive medication. Review of previous trials => #Statins postpone primary outcome by <20 days! ⁦@JournalGIM⁩ https://t.co/bDFbmZbPZn

May 12, 2019 · 3 likes · 5,689 followers View post →
Springer Medicine
@ClinMedJournals · X

RT @JournalGIM: Postponement of Death by Statin Use: a Systematic Review and Meta-analysis of Randomized Clinical Trials https://t.co/rfSfu…

May 10, 2019 · 3 shares · 9,085 followers View post →
Stavros Saripanidis, MD
@DrSaripanidis · X

RT @JournalGIM: Postponement of Death by Statin Use: a Systematic Review and Meta-analysis of Randomized Clinical Trials https://t.co/rfSfu…

May 10, 2019 · 3 shares · 689 followers View post →
JGIM Journal of General Internal Medicine
@JournalGIM · X

Postponement of Death by Statin Use: a Systematic Review and Meta-analysis of Randomized Clinical Trials https://t.co/rfSfurKsQP

May 9, 2019 · 1 like · 3 shares · 8,747 followers View post →