August 2019 PMID 31109263

Association Between Antipsychotic Polypharmacy and Outcomes for People With Serious Mental Illness in England.

Panagiotis Kasteridis, Jemimah Ride, Nils Gutacker, Lauren Aylott, Ceri Dare, Tim Doran, Simon Gilbody, Maria Goddard, Hugh Gravelle, Tony Kendrick, Anne Mason, Nigel Rice, Najma Siddiqi, Rachael Williams, Rowena Jacobs

Mentions

7
Peak: 2 in Jul 2020
across 2 sources since May 2019

Extended reach

75,825
potential audience

Total likes

233

Video views

47,355

Mentions per month

May 2019 – Feb 2021

Where it's discussed

  • X / Twitter5 posts
  • YouTube2 videos

AI synopsis

What people are saying

Several discussions mention that the study supports current guidelines favoring monotherapy, with phrases like 'aligns with recommendations' and 'guidelines suggest,' indicating agreement and interest. The tone suggests a moderate level of engagement, as posters reference the study and contemplate its implications for practice, emphasizing the importance of evidence-based treatment approaches.

AgreementModerate agreement

Most discussions seem to accept the findings, highlighting that polypharmacy does not significantly increase risks and aligns with current guidelines.

InterestModerate interest

Participants show moderate curiosity about the study’s implications, with some posting about the latest research and guidelines.

EngagementModerate engagement

Posts include mentions of the article and some questions about clinical practice, indicating a moderate level of thoughtful engagement.

ImpactModerate impact

The discussion reflects recognition of the research’s relevance for mental health treatment strategies and policy, suggesting a meaningful impact.

Abstract in brief

  • The study examined whether using multiple antipsychotic drugs (polypharmacy) versus a single drug (monotherapy) impacts healthcare use and mortality among adults with serious mental illness in England from 2000 to 2014.
  • The results showed that antipsychotic polypharmacy did not increase the risk of hospital admissions, emergency visits, or death compared to monotherapy, and both approaches were safe in terms of these outcomes.
  • Overall, the findings support current guidelines recommending monotherapy, but also indicate that when polypharmacy is necessary, it does not negatively affect healthcare utilization or survival rates.

Top posts

Most liked on X and Bluesky
James C.Coyne
@CoyneoftheRealm · X

Association Between Antipsychotic Polypharmacy and Outcomes for People With Serious Mental Illness in England. https://t.co/qRlagrJKXj

Jul 7, 2020 · 3 likes · 1 share · 9,548 followers View post →
The Centre for Health Economics
@CHEyork · X

Association between antipsychotic polypharmacy and outcomes for people with serious mental illness in England https://t.co/34Hui8XG2i

Jun 5, 2019 · 2 likes · 5,997 followers View post →
Dr. Daniel J. Winarick
@DrWinarick · X

RT @CoyneoftheRealm: Association Between Antipsychotic Polypharmacy and Outcomes for People With Serious Mental Illness in England. https:…

Jul 7, 2020 · 1 share · 11,168 followers View post →
Europe PMC articles
@EuropePMC · X

New from #OfficialNIHR https://t.co/um61pjmap1 Association between antipsychotic polypharmacy and outcomes for people with serious mental illness in England

Feb 5, 2020 · 1,549 followers View post →

All mentions

Dr. Daniel J. Winarick
@DrWinarick · X

RT @CoyneoftheRealm: Association Between Antipsychotic Polypharmacy and Outcomes for People With Serious Mental Illness in England. https:…

Jul 7, 2020 · 1 share · 11,168 followers View post →
James C.Coyne
@CoyneoftheRealm · X

Association Between Antipsychotic Polypharmacy and Outcomes for People With Serious Mental Illness in England. https://t.co/qRlagrJKXj

Jul 7, 2020 · 3 likes · 1 share · 9,548 followers View post →
Europe PMC articles
@EuropePMC · X

New from #OfficialNIHR https://t.co/um61pjmap1 Association between antipsychotic polypharmacy and outcomes for people with serious mental illness in England

Feb 5, 2020 · 1,549 followers View post →
The Centre for Health Economics
@CHEyork · X

Association between antipsychotic polypharmacy and outcomes for people with serious mental illness in England https://t.co/34Hui8XG2i

Jun 5, 2019 · 2 likes · 5,997 followers View post →
EMR Research papers
@EMR_research · X

Association Between Antipsychotic Polypharmacy and Outcomes for People With Serious Mental Illness in England. https://t.co/3ckT2mz4Lv

May 22, 2019 · 204 followers View post →